Natural killer cell development is blocked in the context of aberrant T lymphocyte ontogeny

International Immunology

Volumn 8, Issue 6, 1996, Pages 939-949

  Wang, Baoping ^a   Holländer, Georg A ^b   Nichogiannopoulou, Aliki ^c   Simpson, Stephen J ^a   Orange, Jordan S ^d   Gutierrez Ramos, Jose Carlos ^c   Burakoff, Steven J ^b   Biron, Christine A ^d   Terhorst, Cox ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BROWN UNIVERSITY   (United States)

Author keywords

Bone marrow transplantation; tg 26 mice; Thymus; Tumor necrosis factor

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL MATURATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; ONTOGENY; PRIORITY JOURNAL; T LYMPHOCYTE; THYMOCYTE; THYMOMA;

ANIMALS; B-LYMPHOCYTES; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; KILLER CELLS, NATURAL; MICE; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTE SUBSETS; THYMUS GLAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030011050     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.6.939     Document Type: Article

References (62)

1. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187.
2. Haller, O., Kiessling, R., Orn, A. and Wigzell, H. 1977. Generation of natural killer cells: an autonomous function of the bone marrow. J. Exp. Med. 145:1411
3. Kumar, V., Ben-Ezra, J., Bennett, M. and Sonnenfeld, G. 1979. Natural killer cells in mice treated with strontium-89: normal target-binding cell numbers but inability to kill even after Interferon administration. J. Immunol. 123:1832.
4. Seaman, W. E., Blackman, M. A., Gindhart, T., Roubinian, J. R., Loeb, M. and Talal, N. 1978. β-Estradiol reduces natural killer cells in mice. J. Immunol. 121:2193.
5. Seaman, W. E., Gindhart, T. D., Greenspan, J. S., Blackman, M. A. and Talal, N. 1979. Natural killer cells, bone, and the bone marrow: studies in estrogen-treated mice and in congenitally osteopetrotic (mi/mi) mice. J. Immunol. 122:2541
6. Hackett, J., Jr, Bosma, G. C., Bosma, M. J., Bennett, M. and Kumar, V. 1986. Transplantable progenitors of natural killer cells are distinct from those of T and B lymphocytes. Proc. Natl Acad. Sci. USA 83:3427.
7. Dorshkind, K., Pollack, S. B., Bosma, M. J. and Phillips, R. A. 1985. Natural killer (NK) cells are present in mice with severe combined immunodeficiency (seid). J. Immunol. 134:3798.
8. Kiessling, R., Klein, E., Pross, H. and Wigzell, H. 1975. 'Natural' killer cells in the mouse. II. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Characteristics of the killer cell. Eur. J. Immunol. 5:17.
9. Habu, S., Shimamura, K., Tamaoki, N., Kumagai, Y. and Okumura, K. 1986. Two natural killer cell populations which belong to T cell lineage in nude mice. Eur. J. Immunol. 16:1453.
10. Mombaerts, P., Iacomini, J., Johnson, R. S., Herrup, K., Tonegawa, S. and Papaioannou, V. E. 1992. Rag-1-deficient mice have no mature B and T lymphocytes. Cell 68:869.
11. Shinkai, Y., Rathbun, G., Lam, K.-P., Oltz, E. M., Stewart, V., Mendelsohn, M., Charron, J., Datta, M., Young, F., Stall, A. M. and Alt, F. W. 1992. Rag-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68:855.
12. Matsuzaki, Y., Gyotoku, J., Ogawa, M., Nishikawa, S., Katsura, Y., Gachelln, G. and Nakauchi, H. 1993. Characterization of c-kit positive intrathymic stem cells that restricted to lymphoid differentiation. J. Exp. Med. 178:1283.
13. - cells in human thymic organ culture. J. Exp. Med. 180:123.
14. Rodewald, H.-R., Moingeon, P., Lucich, J. L., Dosiou, C., Lopez, P. and Reinherz, E. L. 1992. A population of early fetal thymocytes expressing FcγRII/III contains precusors of T lymphocytes and natural killer cells. Cell 69:1.
15. Sanchez, M.-J., Muench, M. O., Roncarolo, M.-G., Lanier, L. L. and Phillips, J. H. 1994. Identification of a common T/natural killer cell progenitor in human fetal thymus. J. Exp. Med. 180:569.
16. Wang, B., Levelt., C. N., Salto, M., Zheng, D., Sancho, J., Liu, C.-P., She, J., Huang, M., Higgins, K., Sunshine, M.-J., Eichmann, K., Lacy, L., Lonberg, N. and Terhorst, C. 1995. Over-expression of Cd3ε transgenes blocks T lymphocyte development. Int. Immunol. 7:435.
17. Wang, B., Biron, C. A., She, J., Higgins, K., Sunshine, M.-J., Lacy, L., Lonberg, N. and Terhorst, C. 1994. A block in both early T lymphocyte and natural killer cell development in transgenic mice with high copy numbers of the CD3ε gene. Proc. Natl Acad. Sci. USA 91:9402.
18. Sihvola, M. and Hurme, M. 1984. The development of NK cell activity in thyrnectomized bone marrow chimeras. Immunology 53:17.
19. Kaminsky, S. G., Milisauskas, V., Chen, P. B. and Nakamura, I. 1987 Defective differentiation of natural killer cells in SJL mice: role of the thymus. J. Immunol. 138:1020.
20. Holländer, G., Wang, B., Nichogiannopoulou, A., Burakoff, S. J., van Ewijk, W., Gutierrez-Ramos, J.-C. and Terhorst, C. 1995. A developmental control point in the induction of the thymic cortex regulated by a subpopulation of prothymocytes. Nature 373:350.
21. Holländer, G., Simpson, S. J., Mizoguchi, E., Nichogiannopoulou, A., She, J., Gutierrez-Ramos, J.-C., Bhan, A. K., Burakoff, S. J., Wang, B. and Terhorst, C. 1995. Severe colitis resulting from aberrant thymic selection. Immunity 3:27.
22. Orange, J. S., Salazar-Mather, T. P., Opal, S. M., Spencer, R. L., Miller, A. H., McEwen, B. S. and Biron, C. A. 1995. Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids. J. Exp. Med. 181:901.
23. Orange, J. S., Wang, B., Terhorst, C. and Biron, C. A. 1995. Requirement for natural killer (NK) cell produced interferon-γ in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration. J. Exp. Med. 182:1045.
24. Roder, J. and Duwe, A. 1979. The beige mutation in the mouse selectively impairs natural killer cell function. Nature 278:451.
25. Bartlett, S. P. and Burton, R. C. 1982. Studies on natural killer (NK) cells: heterogenity of NK cells in Beige mutant mice. Aust. J. Exp. Biol. Med. Sci. 60:571
26. Welsh, R. M. J. and Kiessling, R. W. 1980. Natural killer cell response to lymphocytic choriomeningitis virus in Beige mice. Scand J. Immunol. 11:363.
27. + stem cells: acquisition by NK cells in vivo of the homing receptor MEL-14 and the integrin Mac-1. Immunobiology 190:385.
28. Yankelevich, B., Knobloch, C., Nowicki, M. and Dennert, G. 1989. A novel cell type responsible for marrow graft rejection in mice. T cells with NK phenotype cause acute rejection of marrow grafts. J. Immunol. 142:3423.
29. Sykes, M. 1990. Unusual T cell populations in adult bone marrow J. Immunol. 145:3209-3215.
30. + subset. J. Immunol. 145:1039.
31. + thymocytes selected by MHC class I molecules. Science 263:1774.
32. + cells: new clues to their origin, specificity, and function. J. Exp. Med. 182:633.
33. Shau, H., Roth, M. D. and Golub, S. H. 1993. Regulation of natural killer function by nonlymphoid cells. Nat. Immun. 12:235.
34. Zoller, M. and Wigzell, H. 1982. Normally occurring inhibitory cells for natural killer cell activity. II. Characterization of the inhibitory cell. Cell. Immunol. 74:27.
35. Brunda, M. J., Taramelli, D., Holden, H. T. and Varesio, L. 1983. Suppression of in vitro maintenance and interferon-mediated augmentation of natural killer cell activity by adherent peritoneal cells from normal mice. J. Immunol. 130:1974.
36. Koo, G. C., Manyak, C. L., Dasch, J., Ellingsworth, L. and Shultz, L. D. 1991. Suppressive effects of monocytic cells and transforming growth factor-β on natural killer cell differentiation in autoimmune viable motheaten mutant mice. J. Immunol. 147:1194.
37. Koyasu, S., D'Adamio, L., Arulanandam, A. R. N., Abraham, S., Clayton, L. K. and Reinherz, E. L. 1992. T cell receptor complexes containing FcεRlγ homodimers in lieu of 003ζ and 003η components: a novel isoform expressed on large granular lymphocytes. J. Exp. Med. 175:203
38. - cells. J. Exp. Med. 179:1957.
39. Moore, T., Bennett, M. and Kumar, V. 1995. Transplantable NK cell progenitors in murine bone marrow. J. Immunol. 154:1653.
40. Hurme, M. and Sihvola, M. 1985. Development of natural killer cells: comparison of maturation rates in different lymphoid compartments. Scand. J. Immunol. 21:159.
41. Hurme, M. and Sihvola, M. 1984. High expression of the Thy-1 antigene on natural killer cells recently derived from bone marrow. Cell. Immunol. 84:276.
42. Mombaerts, P., Clarke, A. R., Rudnicki, M. A., Iacomini, J., Itohara, S., Lafaille, J. J., Wang, L., Ichikawa, Y., Jaenisch, R., Hooper, M. L. and Tonegawa, S. 1992. Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages. Nature 360:225.
43. Kitamura, D., Roes, J., Kuhn, R and Rajewsky, K. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 350:423.
44. Philpott, K., Viney, J. L., Kay, G., Rastan, S., Gardiner, E. M., Chae, S., Hayday, A. C. and Owen, M. J. 1992. Lymphoid development in mice congenitally lacking T cell receptor αβ-expressing cells. Science 256:1448.
45. Pollack, S. B. 1993. Production and differentiation of NK ineage cells in bone marrow. Nat. Immun. 12:177
46. Riccardi, C., Migliorati, G., Cannarile, L., F., D., Frati, L. and Herberman, R. B. 1990. In vivo effects of cytokines on development of natural killer cells and antitumor activity in lethally irradiated bone marrow transplanted recipients. J. Biol. Respons. Mod. 9:15.
47. Reiter, Z. 1993. Interferon-a major regulator of natural killer cell-mediated cytotoxicity. J. Interferon Res. 13:247.
48. Bonavida, B., Lebow, L. T. and Jewett, A. 1993. Natural killer cell-subsets: maturation, differentiation and regulation. Nat. Immun. 12:194.
49. Lanier, L. L., Spits, H. and Phillips, J. H. 1992. Developmental relationship of natural killer and T lymphocytes. Immunol. Today 13:392.
50. Spits, H., Lanier, L. L. and Phillips, J. H. 1995. Development of human T and natural killer cells. Blood 85:2654.
51. Fischer, M., MacNeil, I., Suda, T., Cupp, J. E., Shortman, K. and Zlotnik, A. 1991. Cytokine production by mature and immature thymocytes. J. Immunol. 146:3452.
52. - T cells produce IL-4. J. Immunol. 149:1211.
53. - thymocytes with specific lymphokine secretion. Eur. J. Immunol. 23:307.
54. + cells. Proc. Natl Acad. Sci. USA 91:11948.
55. Hughes, D. P. M., Hayday, A., Craft, J. E., Owen, M. J. and Crispe, I. N. 1995. T cells with γ/δ T cell receptors (TCR) of intestinal type are preferentially expanded in TCRα-deficient Ipr mice. J. Exp. Med. 182:233.
56. Su, H. C., Ishikawa, R. and Biron, C. A. 1993. Transforming growth factor-β expression and natural killer cell response during virus infection of normal, nude, and SCID mice. J. Immunol, 151:4874.
57. Su, H. C., Orange, J. S., Fast, L. D., Chan, A. T., Simpson, S. J., Terhorst, C. and Biron, C. A. 1994. IL-2-dependent NK cell responses discovered in virus infected β2-microglobulin-deficient mice, J Immunol. 153:5674.
58. Delfino, D., D'Adamio, F., Migliorati, G. and Riccardi, C. 1991. Growth of murine natural killer cells from bone marrow in vitro: role of TNFα and IFNγ. Int. J. Immunopharmacol. 13:943.
59. Migliorati, G., Cannarile, L., Herberman, R. B. and Riccardi, C. 1989. Effects of various cytokines and growth factors on the interleukin-2-dependent in vitro differentiation of natural killer cells from bone marrow. Nat. Immun. Cell Growth Regul. 8:48.
60. Δ5/Delta;5 mutant mice. Proc. Natl Acad. Sci. USA 92:7545.
61. Malissen, M., Gillet, A., Ardouin, L., Bouvier, G., Trucy, J., Ferrier, P., Vivier, E. and Malissen, B. 1995. Altered T cell development in mice with a targeted mutation of the CD3-ε gene. EMBO J. 14:4641.
62. Takeda, K. and Dennert, G. 1993. The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms. J. Exp. Med. 177:155.