Effect of mechanical set point of bone cells on mechanical control of trabecular bone architecture

Bone

Volumn 22, Issue 2, 1998, Pages 125-131

  Mullender, M ^a   Van Rietbergen, B ^a   Ruegsegger P ^b   Huiskes, R ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Bone architecture; Bone remodeling; Mechanical adaptation; Mechanical set point; Osteoporosis; Trabecular bone

Indexed keywords

ADULT; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE CELL; BONE REMODELING; BONE STRUCTURE; CASE REPORT; COMPUTER SIMULATION; CONTROLLED STUDY; HUMAN; MALE; MATHEMATICAL ANALYSIS; OSTEOCYTE; OSTEOPOROSIS; RISK FACTOR; TRABECULAR BONE;

ADULT; AUTOPSY; BIOMECHANICS; BONE REMODELING; COMPUTER SIMULATION; HUMANS; LUMBAR VERTEBRAE; MALE; MODELS, BIOLOGICAL; OSTEOCYTES; OSTEOPOROSIS; TOMOGRAPHY, X-RAY COMPUTED; WEIGHT-BEARING;

EID: 0031984377     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(97)00251-2     Document Type: Article

References (47)

1. Aarden E. M., Nijweide P. J., van der Plas A., Albas M. J., Mackie E. J., Horton M. A., Helfrich M. H. Adhesive properties of isolated chick osteocytes in vitro. Bone. 18:1996;305-313.
2. Biewener A. A., Fazzalari N. L., Konieczynski D. D., Baudinette R. V. Adaptive changes in trabecular architecture in relation to functional strain patterns and disuse. Bone. 19:1996;1-8.
3. Carvalho R. S., Scott J. E., Suga D. M., Yen E. H. Stimulation of signal transduction pathways in osteoblasts by mechanical strain potentiated by parathyroid hormone. J Bone Miner Res. 9:1994;999-1011.
4. Cheng M. Z., Zaman G., Lanyon L. E. Estrogen enhances the stimulation of bone collagen synthesis by loading and exogenous prostacyclin, but not prostaglandin E2, in organ cultures of rat ulnae. J Bone Miner Res. 9:1994;805-816.
5. Cheng M. Z., Zaman G., Rawlinson S. C. F., Suswillo R. F. L., Lanyon L. E. Oestrogen amplifies bone's osteogenic responses to load-bearing in female rat ulna in vitro. Calcif Tissue Int. 56:1995;428.
6. Cowin S. C., Moss-Salentijn L., Moss M. L. Candidates for the mechanosensory system in bone. J Biomech Eng. 113:1991;191-197.
7. Currey J. D. The effect of porosity and mineral content on the Young's modulus of elasticity of compact bone. J Biomech. 21:1988;131-139.
8. Frost H. M. The Laws of Bone Structure. 1964;Thomas, Springfield, IL.
9. Frost H. M. The mechanostat A proposed pathogenetic mechanism of osteoporosis and the bone mass effects of mechanical and nonmechanical agents . Bone. 2:1987;73-85.
10. Frost H. M. The role of changes in mechanical usage set points in the pathogenesis of osteoporosis. J Bone Miner Res. 7:1992;253-261.
11. Huiskes R. Simulation of self-organization and functional adaptation in bone. Schneider E. Hefte zu "Der Unfallchirurg," Heft 261. Biomechanik des menschlichen Bewegungsapparates. 1997;299-320 Springer, Berlin.
12. Jaworski Z. F., Uhthoff H. K. Reversibility of nontraumatic disuse osteoporosis during its active phase. Bone. 7:1986;431-439.
13. Kannus P., Jarvinen T. L., Sievanen H., Kvist M., Rauhaniemi J., Maunu V. M., Hurme T., Jozsa L., Jarvinen M. Effects of immobilization, three forms of remobilization, and subsequent deconditioning on bone mineral content and density in rat femora. J Bone Miner Res. 11:1996;1339-1346.
14. Kimmel D. B. A paradigm for skeletal strength homeostasis. J Bone Miner Res. 8:(Suppl. 2):1993;S515-S522.
15. Kleerekoper M., Villanueva A. R., Stanciu J., Rao D. S., Parfitt A. M. The role of three-dimensional trabecular microstructure in the pathogenesis of vertebral compression fractures. Calcif Tissue Int. 37:1985;594-597.
16. Klein-Nulend J., Van der Plas A., Semeins C. M., Ajubi N. E., Frangos J. A., Nijweide P. J., Burger E. H. Sensitivity of osteocytes to biomechanical stress in vitro. Fed Eur Biochem J. 9:1995;441-445.
17. Krolner B., Toft B. Vertebral bone loss An unheeded side effect of therapeutic bed rest . Clin Sci. 64:1983;537-540.
18. Lanyon L. E. The success and failure of the adaptive response to functional load-bearing in averting bone fracture. Bone. 13:(Suppl. 2):1992;S17-S21.
19. Lanyon L. E. Osteocytes, strain detection, bone modeling and remodeling. Calcif Tissue Int. 53:(Suppl. 1):1993;S102-S106.
20. Lean J. M., Mackay A. G., Chow J. W., Chambers T. J. Osteocytic expression of mRNA for c-fos and IGF-I An immediate early gene response to an osteogenic stimulus . Am J Physiol. 270:1996;E937-E945.
21. Li X. J., Jee W. S., Chow S. Y., Woodbury D. M. Adaptation of cancellous bone to aging and immobilization in the rat A single photon absorptiometry and histomorphometry study . Anat Rec. 227:1990;12-24.
22. Marotti G., Cané V., Palazzini S., Palumbo C. Structure-function relationships in the osteocyte. Ital J Miner Electrolyte Metab. 4:1990;93-106.
23. McDonald F., Yettram A. L. Loading of cells and a possible upper limit of load response with respect to strain energy density. J Biomed Mater Res. 29:1995;1577-1585.
24. Moore R. J., Durbridge T. C., McNeil P. J., Parkinson I. H., Need A. G., Vernon-Roberts B. Trabecular spacing in post-menopausal Australian women with and without vertebral fractures. Aust NZ J Med. 22:1992;269-273.
25. Mosekilde L. Consequences of the remodelling process for vertebral trabecular bone structure A scanning electron microscopy study (uncoupling of unloaded structures) . Bone Miner. 10:1990;13-35.
26. Mullender M. G., Huiskes R. A proposal for the regulatory mechanism of Wolff's law. J Orthop Res. 13:1995;503-512.
27. Mullender M. G., Huiskes R., Weinans H. A physiological approach to the simulation of bone remodeling as a self-organizational control process [technical note]. J Biomech. 27:1994;1389-1394.
28. Mullender M. G., Van der Meer D. D., Huiskes R., Lips P. Osteocyte density changes in aging and osteoporosis. Bone. 18:1996;109-113.
29. Palle S., Vico L., Bourrin S., Alexandre C. Bone tissue response to four-month antiorthostatic bedrest A bone histomorphometric study . Calcif Tissue Int. 51:1992;189-194.
30. Parfitt A. M. Age-related structural changes in trabecular and cortical bone Cellular mechanisms and biomechanical consequences . Calcif Tissue Int. 36:(Suppl. 1):1984;S123-S128.
31. Parfitt A. M. Skeletal heterogeneity and the purposes of bone remodeling. Marcus R., Feldman D., Kelsey J. Osteoporosis. 1996;315-329 Academic, San Diego.
32. Parfitt A. M., Mathews C. H. E., Villanueva A. R., Kleerekoper M. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and osteoporosis. J Clin Invest. 72:1983;1396-1409.
33. Pead M. J., Suswillo R., Skerry T. M., Vedi S., Lanyon L. E. Increased 3H-uridine levels in osteocytes following a single short period of dynamic bone loading in vivo. Calcif Tissue Int. 43:1988;92-96.
34. Recker R. R., Kimmel D. B., Parfitt A. M., Davies M., Keshawarz N., Hinders S. Static and tetracycline-based bone histomorphometric data from 34 normal post-menopausal females. J Bone Miner Res. 3:1988;133-144.
35. Rho J. Y., Ashman R. B., Turner C. H. Young's modulus of trabecular and cortical bone material Ultrasonic and microtensile measurements . J Biomech. 26:1992;111-119.
36. Rodan G. A. Coupling of bone resorption and formation during bone remodeling. Marcus R., Feldman D., Kelsey J. Osteoporosis. 1996;289-299 Academic, San Diego.
37. Rüegsegger P., Koller B., Muller R. A microtomographic system for the nondestructive evaluation of bone architecture. Calcif Tissue Int. 58:1996;24-29.
38. Schaffler M. B., Pan H. Q. Alterations of trabecular microarchitecture during immobilization-induced bone loss. Trans Orthop Res Soc. 17:1992;239.
39. Skerry T. M., Bitensky L., Chayen J., Lanyon L. E. Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo. J Bone Miner Res. 4:1989;783-788.
40. Steiniche T., Christiansen P., Vesterby A., Hasling C., Ullerup R., Mosekilde L., Melsen F. Marked changes in iliac crest bone structure in postmenopausal osteoporotic patients without any signs of disturbed bone remodeling or balance. Bone. 15:1994;73-79.
41. Thomas T., Skerry T. M., Vico L., Caulin F., Lanyon L. E., Alexandre C. Ineffectiveness of calcitonin on a local-disuse osteoporosis in the sheep A histomorphometric study . Calcif Tissue Int. 57:1995;224-228.
42. Thomas T., Vico L., Skerry T. M., Caulin F., Lanyon L. E., Alexandre C., Lafage M. H. Architectural modifications and cellular response during disuse-related bone loss in calcaneus of the sheep. J Appl Physiol. 80:1996;198-202.
43. Van Rietbergen B., Mullender M. G., Huiskes R. A three dimensional model for the osteocyte-regulated remodeling simulation at the tissue level. Middleton J. Computer Methods in Biomechanics and Biomedical Engineering. 1996;73-83 Books & Journals, Swansea, UK.
44. Van Rietbergen B., Odgaard A., Kabel J., Huiskes R. Direct mechanics assessment of mechanical symmetries and properties of trabecular bone architecture. J Biomech. 29:1996;1653-1657.
45. Van Rietbergen B., Weinans H., Huiskes R., Odgaard A. A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models. J Biomech. 28:1995;69-81.
46. Van Rietbergen B., Weinans H., Polman B. J. W., Huiskes R. Computational strategies for iterative solutions of large FEM applications employing voxel data. Int J Numer Meth Eng. 39:1996;2743-2767.
47. Weinans H., Prendergast P. J. Tissue adaptation as a dynamical process far from equilibrium. Bone. 19:1996;143-149.