Human intestinal M cells exhibit enterocyte-like intermediate filaments

Gut

Volumn 42, Issue 1, 1998, Pages 54-62

  Kucharzik, T ^a   Lugering N ^a   Schmid, K W ^a   Schmidt, M A ^a   Stoll, R ^a   Domschke, W ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Appendix; Cytokeratin; Follicle associated epithelium; Human intestinal M cells; Intermediate filaments

Indexed keywords

CYTOKERATIN; DESMIN; VIMENTIN;

ADULT; AGED; APPENDIX; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT; INTESTINE CELL; M CELL; MALE; PRIORITY JOURNAL;

EID: 0031982098     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.42.1.54     Document Type: Article

References (43)

1. Owen RL, Jones AL. Epithelial cell specialization within human Peyer's patches: an ultrastructural study of intestinal lymphoid follicles. Gastroenterology 1974;66:189-203.
2. Bockman DE, Cooper MD. Early lymphoepithelial relationships in human appendix. A combined light- and electronmicroscopic study. Gastroenterology 1975;68:1160-8.
3. Neutra MR, Phillips TL, Mayer EL, Fishkind DJ. Transport of membrane-bound macromolecules by M-cells in follicle associated epithelium of rabbit Peyer's patch. Cell Tissue Res 1987;247:537-46.
4. Wolf JL, Bye WA. The membraneous epithelial (M) cell and the mucosal immune system. Annu Rev Med 1984;35:95-112.
5. Bockman DE, Stevens W. Gut associated lymphoepithelial tissue: bidirectional transport of tracer by specialized epithelial cells associated with lymphoid follicles. J Reticuloendothel Soc 1977;21:245-54.
6. Jepson MA, Simmons KL, Savidge TC, James PS, Hirst BH. Selective binding and transcytosis of latex microspheres by rabbit intestinal m cells. Cell Tissue Res 1993;271:399-405.
7. Trier JS. Structure and function of M cells. Gastroenterol Clin North Am 1991;20:531-47.
8. Owen RL. And now pathophysiology of M-cells - good news and bad news from Peyer's patches. Gastroenterology 1983;85:468-70.
9. Wolf JL, Kauffman RS, Finberg R, Dambrauskas R, Fields BN, Trier JS. Determinants of reovirus interaction with the intestinal M cells and absorptive cells of murine intestine. Gastroenterology 1983;85:291-300.
10. Pappo J, Steger H, Owen R. Differential adherence of epithelium overlying gut-associated lymphoid tissue. Lab Invest 1988;58:692-7.
11. Jones BD, Ghori N, Falkow S. Salmonella typhimurium initiates murine infection by penetration and destroying the specialized epithelial M cells of the Peyer's patches. J Exp Med 1994;180:15-23.
12. Sass W, Dreyer HP, Seifert J. Rapid insorption of small particles in the gut. Am J Gastroenterol 1990;85:255-60.
13. Owen RL, Nemanic P. Antigen processing structures of the mammalian intestinal tract: an SEM study of lymphoepithelial organs. In: Becker RP, Johari O, eds. Scanning electron microscopy. 1978;11:367-78.
14. Owen RL, Bhalla DK. Cytochemical analysis of alkaline phosphatase and esterase activities and of lectin-binding and anionic sites in rat and mouse Peyer's patch M cells. Am J Anat 1983;168:199-212.
15. Gebert A, Rothkötter HJ, Pabst R. Cytokeratin 18 is an M-cell marker in porcine Peyer's patches. Cell Tissue Res 1994;276:213-21.
16. Gebert A, Hach G, Bartels H. Co-localization of vimentin and cytokeratins in M-cells of rabbit gut-associated lymphoid tissue (GALT). Cell Tissue Res 1992;269:331-40.
17. Rautenberg K, Cichon C, Heyer G, Demel M, Schmidt MA. Immunocytochemical characterization of the follicle-associated epithelium of Peyer's patches: anticytokeratin-8 antibody (clone 4.1.18) as a molecular marker for rat M cells. Eur J Cell Biol 1996;71:363-70.
18. Moll R, Franke WW, Schiller D. The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 1982;31:11-24.
19. Roth J. The protein A-gold (pAg) technique: a qualitative and quantitative approach for antigen localization on thin sections. In: Bullock GR, Petrusz, eds. Techniques in immunocytochemistry. Vol 1. New York: Academic Press, 1982:108-33.
20. Moll R, Löwe A, Laufer J, Franke WW. Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol 1992;140:427-47.
21. Lazarides E. Intermediate filaments as mechanical integrators of cellular space. Nature 1980;283:249-56.
22. Steinert PM, Parry DAD. Intermediate filaments: conformity and diversity of expression and structure. Annu Rev Cell Biol 1990;1:41-65.
23. Jepson MA, Mason CM, Benett MK, Simmons XL, Hirst BH. Co-expression of vimentin and cytokeratins in M cells of rabbit intestinal lymphoid follicle-associated epithelium. Histochem J 1992;24:33-9.
24. Franke WW, Schmidt E, Osborn M, Weber K. Different intermediate sized filaments distinguished by immunofluorescence microscopy. Proc Natl Acad Sci USA 1978;75: 5034-8.
25. Mooseker MS. Organization, chemistry, and assembly of the cytoskeletal apparatus of the intestinal brush border. Annu Rev Cell Biol 1985;1:209-41.
26. Kerneis S, Bogdanova, Colucci-Guyon E, Kraehenbuhl, Pringault E. Cytosolic distribution of villin in M cells from mouse Peyer's patches with the absence of a brush border. Gastroenterology 1996;110:515-21.
27. Stewart M. Intermediate filaments: structure, assembly and molecular interactions. Curr Opin Cell Biol 1990;2:91-100.
28. Steinert PM, Roop DR. Molecular and cellular biology of intermediate filaments. Annu Rev Biochem 1988;57:593-625.
29. Bhalla DK, Owen RL. Cell renewal and migration in lymphoid follicles of Peyer's patches and cecum - an autoradiographic study in mice. Gastroenterology 1982;82:232-42.
30. Smith MW, Peacock MA. Lymphocyte induced formation of antigen transporting "M" cell distribution in follicle associated epithelium of mouse Peyer's patch. Am J Anat 1980;159:167-75.
31. Smith MW, Peacock MA. Microvillus growth and M-cell formation in mouse Peyer's patch follicle-associated epithelial tissue. Exp Physiol 1992;77:389-92.
32. Bockman DE. Functional histology of appendix. Arch Histol Jpn 1983;46:271-92.
33. Sicinsky P, Rowinsky J, Warchol JB, Bem W. Morphometric evidence against lymphocyte-induced differentiation of M cells from absorptive cells in mouse Peyer's patches. Gastroenterology 1986;90:609-16.
34. Bye WA, Allan CH, Trier JS. Structure, distribution, and origin of M cells in Peyer's patches of mouse ileum. Gastroenterology 1984;86:789-801.
35. Kernéis S, Bogdanova A, Kraehenbuhl JP, et al. Conversion by Peyer's patch lymphocytes of human enterocytes into M cells that transport bacteria. Science 1997;277:949-52.
36. Giannasca PJ, Giannasca KT, Falk P, Gordon JI, Neutra MR. Regional differences in glycoconjugates of intestinal M cells in mice: potential targets for mucosal vaccines. Am J Physiol 1994;267:G1108-21.
37. Neutra MR, Phillips TL, Mayer HL, Fishkind DJ. Transport of membrane-bound macromolecules by M cells in follicle-associated epithelium of rabbit Peyer's patch. Cell Tissue Res 1987;247:537-46.
38. Gebert A, Hach G. Differential binding of lectins to M cells and enterocytes in the rabbit cecum. Gastroenterology 1993; 105:1350-61.
39. Neutra MR, Frey A, Kraehenbuhl J-P. Epithelial M cells: gateways for mucosal infection and immunization. Cell 1996;86:345-8.
40. Wolf JL, Rubin DH, Finberg R, Kauffman RS, Sharpe AH, Trier JS, Fields N. Intestinal M cells: a pathway for entry of reovirus into the host. Science 1981;212:71-2.
41. Inman LR, Cantey JR. Specific adherence of Escherichia coli (strain RDEC-1) to membranous (M) cells of the Peyer's patch in Escherichia coli diarrhea in the rabbit. J Clin Invest 1983;71:1-8.
42. Neutra MR, Pringault E, Kraehenbuhl JP. Antigen-sampling across epithelial barriers and induction of mucosal immune responses. Annu Rev Immunol 1996;14: 275-300.
43. Savidge TC, Smith MW. Evidence that membranous cell genesis is immunoregulated. In: Mestecky J, ed. Advances in musosal immunology. New York: Plenum Press, 1995:239-41.