Molecular control of the LDL receptor gene ln leukemic cells

Leukemia Research

Volumn 22, Issue 1, 1998, Pages 89-92

  Goel, Rajeev ^a   Kaul, D ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; DNA; DNA BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN RECEPTOR; TRANSCRIPTION FACTOR;

CHOLESTEROL METABOLISM; LEUKEMIA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; RECEPTOR GENE; SHORT SURVEY; TRANSCRIPTION REGULATION;

GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKEMIA; LIPOPROTEINS, LDL; RECEPTORS, LDL;

EID: 0031980922     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(97)00088-X     Document Type: Short Survey

References (47)

1. 1. Siperstein, M. D., Role of cholesterogenesis and isoprenoid synthesis in DNA replication and cell growth. Journal of Lipid Research, 1984, 25, 1462.
2. 2. Vitols, S., Gahrton, G., Ost, A. and Peterson, C., Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation. Blood, 1984, 63, 1186.
3. 3. Siperstein, M. D., Regulation of cholesterol biosynthesis in normal and malignant tissues. Current Topics in Cellular Regulation, 1970, 2, 65.
4. 4. Polsky, F. I., Brown, M. S. and Siperstein, M. D., Feedback control of cholesterol synthesis in circulating granulocytes and deletion of feedback control in a granulocytic leukemia. Journal of Clinical Investigation, 52, 1973, 65(a) (Abstract No. 240).
5. 5. Inbar, M. and Shinilzky, M., Cholesterol as a bioregulator in the development and inhibition of leukemia. Proceedings of the National Academv of Science of the USA, 1974, 71, 4229.
6. 6. Muller, C. P., Wagner, A. U., Maucher, C. and Steinke, B., Hypocholesterolemia, an unfavourable feature of prognostic value in chronic myeloid leukemia. European Journal of Haematology, 1989, 43, 235.
7. 7. Buchwald, H., Cholesterol inhibition, cancer and chemotherapy. Lancet, 1992, 339, 1154.
8. 8. Vitols, S., Gahrton, G., Bjorkholm, M. and Peterson, G., Hypocholesterolemia in malignancy due to elevated low density lipoprotein receptor activity in tumor cells: evidence from studies in patients with leukemia. Lancet, 1985, ii, 1150.
9. 9. Peterson, C., Vitols, S., Rudling, M., Blomgren, H., Edsmyr, F. and Skoog, L., Hypocholesterolemia in cancer patients may be caused by elevated LDL receptor activities in malignant cells. Medical Oncology & Tumor Pharmacotherapy, 1985, 2, 143.
10. 10. Sainte, M. J., Vidal, M., Philippot, J. R. and Bienvenue, A., Characterization of low density lipoprotein receptors in freshly isolated leukemic guinea pig lymphocytes (L2C). Journal of Receptor Research, 1985, 5, 171.
11. 11. Vitols, S., Uptake of low density lipoprotein by malignant cells possible therapeutic applications. Cancer Cells, 1991, 3, 488.
12. 12. Bricker, L. A., Morris, H. P. and Siperstein, M. D., Loss of cholesterol feedback system in the intact hepatoma bearing rat. Journal of Clinical Investigation, 1972, 51, 206.
13. 13. Ho, Y. K., Smith, R. G., Brown, M. S. and Goldstein, J. L., Low density lipoprotein receptor activity in human acute myelogenous leukemia. Blood, 1978, 52, 1099.
14. 14. Gilbert, H. S. and Ginsberg, H., Hyocholesterolemia as a manifestation of disease activity in chronic myelogenous leukemia. Cancer, 1983, 51, 1428.
15. 15. Gilbert, H. S., Ginsberg, H., Fagerstrom, R. and Brown, W. V., Characterization of hypocholesterolemia in myeloproliferative disease. Relation to disease manifestations and activity. American Journal of Medicine, 1981, 71, 595.
16. k" deficiency initiates leukemia? Cancer Letters, 1997, 112, 199.
17. 17. Goldstein, J. L. and Brown, M. S., Regulation of the mevalonate pathway. Nature, 1990, 343, 425.
18. 18. Smith, J. R., Osborne, T. F., Goldstein, J. L. and Brown, M. S., Identification of nucleotides responsible for enhancer activity of sterol regulatory element in LDL receptor gene. Journal of Biological Chemistry, 1990, 265, 2306.
19. 19. Smith, J. R., Osborne, T. F., Goldstein, J. L. and Gil, G., Multiple sterol regulatory elements in promoter for hamster 3-hydroxy-3-methylglutarylcoenzyme A synthase. Journal of Biological Chemistry, 1988, 263, 18480.
20. 20. Metherall, J. E., Goldstein, J. L., Luskey, K. L. and Brown, M. S., Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells. Journal of Biological Chemistry, 1989, 264, 15634.
21. 21. Rajavashisth, T. B., Taylor, A. K., Andalibi, A., Svenson, K. L. and Lusis, A. J., Identification of a zinc finger protein that binds to sterol regulatory element. Science, 1989. 245, 640.
22. 22. Sudhof, T. C., Russel, D. W., Brown, M. S. and Goldstein, J. L., 42 bp element from LDL receptor gene confers endproduct repression by sterols when inserted into the viral TK promoter. Cell, 1987, 48, 1061.
23. 23. Dawson, P. A., Hofmann, S. L., Van der Westhuyzen, D. R., Sudhof, T. C., Brown, M. S. and Goldstein, J. L., Sterol dependent repression of low density lipoprotein receptor promoter mediated by 16 base pair sequence adjacent to binding site for transcription factor Spl. Journal of Biological Chemistry. 1988, 263, 3372.
24. 24. Sudhof, T. C., Vander Westhuyzen, D. R., Goldstein, J. L., Brown, M. S. and Russell, D. W., Three direct repeats and a TATA like sequence are required for regulated expression of the human low density lipoprotein receptor gene. Journal of Biological Chemistry, 1987, 262, 10773.
25. 25. Stark, H. C., Weinberger, O. and Weinberger, J., Common double and single stranded DNA binding factor for a sterol regulating element. Proceeding of the National Academy of Science of the USA, 1992, 89, 2180.
26. 26. Goel, R. and Kaul, D., Isolation and nature of a protein factor having affinity for the SRE sequence in the promotor of LDL receptor gene. International Journal in Progress in Cardiovascular Science, 1996, 3, 88.
27. 27. Goel, R., Kaul, D. and Varma, S., Lymphocytes from CML patients lack a 47 kDa factor having affinity for genomic sterol regulatory sequence. Leukemia Research, 1996, 20, 877.
28. 28. Goel, R., Varma, S. and Kaul, D., Sterol dependent LDL receptor gene transcription in lymphocytes from normal and CML patients. Cancer Letters, 1996, 103, 193.
29. 29. Briggs, M. R., Yokoyama, C., Wang, X., Brown, M. S. and Goldstein, J. L., Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I: Identification of the protein and delineation of its target nucleotide sequence. Journal of Biological Chemistry, 1993, 268, 14490.
30. 30. Wang, X., Briggs, M. R., Hua, X., Yokoyama, C., Goldstein, J. L. and Brown, M. S., Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter: Purification and Characterization. Journal of Biological Chemistry, 1993, 268, 14497.
31. 31. Wang, X., Sato, R., Brown, M. S., Hua, X. and Goldstein, J. L., SREBP1 a membrane bound transcription factor released by sterol regulated proteolysis. Cell, 1994, 77, 53.
32. 32. Sheng, Z., Otani, H., Brown, M. S. and Goldstein, J. L., Independent regulation of sterol regulatory element binding proteins 1 and 2 in hamster liver. Proceedings of the National Academy of Science of the USA, 1995, 92, 935.
33. 33. Osborne, T. F., Cholesterol homeostasis: Clipping out a slippery regulator. Current Biology, 1997, 7, R172.
34. 34. Wang, X., Pai, J. T., Wiedenfeld, E. A., Medina, J. C., Slaughter, C. A., Goldstein, J. L. and Brown, M. S., Purification of interleukin 1β converting enzyme related cysteine protease that cleaves sterol regularoty element binding proteins between the leucine zippers and transmembrane domains. Journal of Biological Chemistry, 1995, 270, 18044.
35. 35. Hua, X., Nohturfft, A., Goldstein, J. L. and Brown, M. S., Sterol resistance in CHO cells tranced to point mutation in SREBP cleavage activating protein. Cell, 1996, 87, 415.
36. 36. Hua, X., Sakai, J., Ho, Y. K., Goldstein, J. L. and Brown, M. S., Regulated cleavage of sterol regulatory element binding proteins (SREBPs) requires sequences on both sides of endoplasmic reticulum membrane. Journal of Biological Chemistry, 1996, 271, 10379.
37. 37. Sakai, J., Duncan, E. A., Rawson, R. B., Hua, X., Brown, M. S. and Goldstein, J. L., Sterol regulated release from the membranes required two sequential cleavage. One within a transmembrane segment. Cell, 1996, 85, 1037.
38. 38. Gil, G., Faust, J. R., Chin, D. J., Goldstein, J. L. and Brown, M. S., Membrane bound domain of HMG CoA reductase is required for sterol enhanced degradation of the enzyme. Cell, 1985, 41, 249.
39. 39. Kochhar, N. and Kaul, D., Molecular link between membrane cholesterol and cyclic nucleotides in human platelets. Blood Coagulation and Fibrinolysis, 1992, 3, 215.
40. 2 in platelets upon cholesterol incorporation. FEBS, 1992, 314, 17.
41. + exchange within human platelets. FEBS, 1992, 299, 19.
42. 42. Kaul, D., Do human platelets possess LDL-receptor specific for apoprotein B or cholesterol? Current Science, 1993, 65, 883.
43. K" activationresponse coupling in human platelets. Platelets, 1995, 6, 306.
44. 44. Kaul, D. and Singh, J., Exogenous cholesterol initiated transmembrane signalling pathway regulates cholesterogenesis in human platelets. Cellular Signalling, 1994, 6, 141.
45. K"-dependent signalling in human platelets. Molecular and Cellular Biochemistry, 1995, 151, 173.
46. 46. Kaul, D., Dhawan, V. and Kaur, M., Nature and evidence of novel thiol oxidase in human platelets. Molecular and Cellular Biochemistry, 1996, 159, 81.
47. K" dependent signalling regulates the LDL-Receptor gene transcription. Molecular and Cellular Biochemistry, 1997, 169, 79.