The low cycling status of mobilized peripheral blood CD34+ cells is not restricted to the more primitive subfraction

Leukemia

Volumn 12, Issue 4, 1998, Pages 571-577

  Croockewit, A J ^a   Raymakers, R A P ^a   Smeets, M E P ^a   Vd Bosch, G ^a   Pennings, A H M ^a   De Witte, T J M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cell cycle; Hematopoietic stem cells; Immunophenotyping; Rhodamine

Indexed keywords

CD33 ANTIGEN; CD34 ANTIGEN; MICROSOMAL AMINOPEPTIDASE;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STEM CELL;

EID: 0031979846     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2400981     Document Type: Article

References (14)

1. Beyer J, Schwella N, Zingsem J, Strohscheer I, Schwaner I, Oettle H, Serke S, Huhn D, Stieger W. Hematopoietic rescue after high-dose chemotherapy using autologous peripheral-blood progenitor cells or bone marrow: a randomized comparison. J Clin Oncol 1995; 13: 1328-1335.
2. Schmitz N, Linch DC, Dreger P, Goldstone AH, Boogaerts MA, Ferrant A, Demuynck HM, Link H, Zander A, Barge A, Borkett K. Randomised trial of filgrastim-mobilized peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients. Lancet 1996; 347: 353-357.
3. Lévesque J, Leavesley DI, Niutta S, Vadas M, Simmons PJ. Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins. J Exp Med 1995; 181: 1805-1815.
4. Papayannopoulou T, Nakamoto B. Peripheralization of hematopoietic progenitors in primates treated with anti-VLA4 integrin. Proc Natl Acad Sci USA 1993; 90: 9374-9378.
5. +cells. Blood 1994; 84: 2930-2939.
6. Roberts AW, Metcalf D. Non cycling state of peripheral blood progenitor cells mobilized by granulocyte colony-stimulating factor and other cytokines. Blood 1995; 86: 1600-1605.
7. Siegert W, Serke S. Cytokine mobilized blood CD34-expressing cells are not cycling (letter). Bone Marrow Transplant 1996; 17: 467-470.
8. +cells in Thy-1 expression and cell cycle status in non human primates mobilized or not mobilized with granulocyte colony-stimulating factor and/or stem cell factor. Blood 1996; 87: 1644-1653.
9. + cells in cord blood and in cytokine-mobilized blood. Br J Haematol 1996; 92: 255-262.
10. Rutella S, Rumi C, Teofili L, Benedic E, Ortu ALA, Barvera E, Leone G. RhG-CSF mobilized peripheral blood haemopoietic progenitors reside in G0/G1 phase of cell cycle independently of the expression of myeloid antigens. Br J Haematol 1996; 93: 737-741.
11. Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood 1993; 81: 2844-2853.
12. Ploemacher RE, Brons NHC. Cells with marrow and spleen repopulating ability and forming spleen colonies on day 16, 12 and 8 are sequentially ordered on the basis of increasing rhodamine 123 retention. J Cell Physiol 1988; 136: 531-536.
13. Mulder AH, Visser JWM. Separation and functional analysis of bone marrow cells separated by Rhodamine 123 fluorescence. Exp Hematol 1987; 15: 99-104.
14. Bertoncello I, Hodgson CS, Bradley TR. Multiparameter analysis of transplantable hemopoietic stem cells. I. The separation and enrichment of stem cells homing to the marrow and spleen on the basis of Rhodamine 123 fluorescence. Exp Hematol 1985; 13: 999-1006.