Lack of DNA synthesis among CD34+ cells in cord blood and in cytokine-mobilized blood

British Journal of Haematology

Volumn 92, Issue 2, 1996, Pages 255-262

  Leitner, Agnes ^a   Strobl, Herbert ^b   Fischmeister, Gustav ^a   Kurz, Martin ^b   Romanakis, Kostas ^c   Haas, Oskar A ^a   Printz, Dieter ^a   Buchinger, Petra ^a   Bauer, Silvia ^a   Gadner, Helmut ^a   Fritsch, Gerhard ^a  

^a ST ANNA CHILDREN S HOSPITAL   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c University of Koblenz Landau   (Germany)

Author keywords

Blood; Bone marrow; CD34; Cord blood; DNA analysis; Flow cytometry

Indexed keywords

CD34 ANTIGEN; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; STEEL FACTOR;

ARTICLE; BLOOD; BONE MARROW; CELL CYCLE; CELL MIGRATION; CELL PROLIFERATION; DNA SYNTHESIS; FLOW CYTOMETRY; HEMATOPOIESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PRIORITY JOURNAL;

EID: 9044239677     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.d01-1473.x     Document Type: Article

References (40)

1. Aglietta, M., Piacibello, W., Sanavio, F., Stacchini, A., Apra, F., Schena, M., Mossetti, C., Carnino, F., Caligaris-Cappio, F. & Gavosto, F. (1989) Kinetics of human hemopoietic cells after in vivo administration of granulocyte-macrophage colony-stimulating factor. Journal of Clinical Investigation, 83, 551-557.
2. Brons, P.P.T., Pennings, A.H.M., Haanen, C., Wessels, H.M.C. & Boezeman, J.B.M. (1990) Simultaneous measurement of DNA content and cell-surface immunolluorescence of human bone marrow cells using a single laser flow cytometer. Cytometry, 11, 837-844.
3. Broxmeyer, H.E., Benninger, L., Patel, S.R., Benjamin, R.S. & Vadhan-Raj, S. (1994) Kinetic response of human marrow myeloid progenitor cells to in vivo treatment of patients with granulocyte colony-stimulating factor is different from the response to treatment with granulocyte-macrophage colony-stimulating factor. Experimental Hematology, 22, 100-102.
4. Broxmeyer, H.E., Cooper, S. & Vadhan-Raj, S. (1989) Cell cycle status of erythroid (BFU-E) progenitor cells from bone marrows of patients on a clinical trial with purified recombinant human granulocyte-macrophage colony-stimulating factor. Experimental Hematology, 17, 455-459.
5. Broxmeyer, H.E., Cooper, S., Williams, D.E., Hangoc, G., Gutterman, J.U. & Vadhan-Raj, S. (1988) Growth characteristics of marrow haematopoietic progenitor/precursor cells from patients on a phase I clinical trial with purified recombinant human granulocyte-macrophage colony-stimulating factor. Experimental Hematology, 16, 594-602.
6. Carow, C.E., Hangoc, G. & Broxmeyer, H.E. (1993) Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: an effect enhanced by cord blood plasma. Blond, 81, 942-949.
7. Darzynkiewicz, Z. (1990) Differential staining of DNA and RNA in intact cells and isolated cell nuclei with acridine orange. Methods in Cell Biology (ed. by Z. Darzynkiewicz and H. A. Crissman), p. 285. Academic Press, San Diego.
8. Dreger, P., Haferlach, T., Eckstein, V., Jacobs, S., Suttorp, M., Löffler, H., Müller-Ruchholz, W. & Schmitz, N. (1994) G-CSF-mobilized peripheral blood progenitor cells for allogeneic transplantation: safety, kinetics of mobilization, and composition of the graft. British Journal of Haematalogy, 87, 609-613.
9. Ellas, A.D., Ayash, L., Anderson, K.C., Hunt, M., Wheeler, C., Schwartz, G., Tepler, I., Mazanet, R., Lynch, C., Pap, S., Palaez, J., Reich, E., Critchlow, J., Demetri, G., Bibbo, J., Schnipper, L., Griffin, J.D., Frei, E. & Antmann, K.H. (1992) Mobilization of peripheral blood progenitor cells by chemotherapy and granulocyte-macrophage colony-stimulating factor for hematologic support after high-dose intensification for breast cancer. Blood, 79, 3036-3044.
10. Fritsch, G., Buchinger, P. & Printz, D. (1993a) Use of flow cytometric CD34 analysis to quantify hematopoietic progenitor cells. Leukemia and Lymphoma, 10, 443-451.
11. Fritsch, G., Buchinger, P., Printz, D., Dworzak, M.D., Strunk, D., Agis, H., Sliutz, G., Wilfing, A., Schulz, U. & Gadner, H. (1994a) Is CD33 a differentiation marker? Progress in Clinical and Biological Research, 389, 377-382.
12. + myeloid progenitors using CD45-RA analysis. Blood, 81, 2301-2309.
13. Fritsch, G., Fischmeister, G., Haas, O.A., Peters, C., Gadner, H., Strobl, H., Hoecker, P. & Kurz, M. (1994b) Peripheral blood hemopoietic progenitor cells of cytokine-stimulated healthy donors as an alternative for allogeneic transplantation. (Letter). Blood, 83, 3420-3421.
14. Fritsch, G., Fischmeister, G., Kurz, M., Strobl, H., Leitner, A., Haas, O.A., Buchinger, P., Printz, D., Ströbel, T., Scheinecker, C., Knapp, W. & Gadner, H. (1994c) In vivo comparison of G-CSF and GM-CSF: clinical study in healthy adults. (Abstract). Bone Marrow Transplantation, 14, (Suppl. 1), S11.
15. Hengstschläger, M., Knöfler, M., Müllner, E.W., Ogris, W., Wintersberger, E. & Wawra, E. (1994) Different regulation of thymidine kinase during the cell cycle of normal versus DNA tumor virus-transformed cells. Journal of Biological Chemistry, 269, 13836-13842.
16. Hollander, Z. & Loken, M.R. (1988) Simultaneous analysis of DNA content and surface antigens in human bone marrow. Cytometry, 9, 485-490.
17. Hollander, Z., Shah, V.O., Civin, C.I. & Loken, M.R. (1988) Assessment of proliferation during maturation of the B lymphoid lineage in normal human bone marrow. Blood. 71, 528-531.
18. Kanz, L., Brugger, W. & Mertelsmann, R. (1993) Haematopoietic growth factors and peripheral blood stem cells as supportive agents in dose intensification. European Journal of Cancer, 29A, S23-S26.
19. Kerst, J.M., de Haas, M., van der Schoot, C.E., Slaper-Cortenbach, I.C.M., Kleijer, M., von dem Borne, A.E.G.K. & van Oers, R.H.J. (1993) Recombinant granulocyte colony-stimulating factor administration to healthy volunteers: induction of immunophenotypically and functionally altered neutrophils via an effect on myeloid progenitor cells. Blood, 82, 3265-3272.
20. Kreissig, C., Kirsch, A. & Serke, S. (1994) Characterization and measurement of CD34-expressing hematopoietic cells. Journal of Hematotherapy, 3, 263-289.
21. + bone marrow cells in relation to their colony formation. Blood, 81, 3211-3216.
22. Laver, J., Duncan, E., Abboud, M., Gasparetto, C., Sahdev, I., Warren, D., Bussel, J., Auld, P., O'Reilly, R.J. & Moore, M.A.S. (1990) High levels of granulocyte and granulocyte-macrophage colony-stimulating factors in cord blood of normal full-term neonates. Journal of Pediatrics, 116, 627-632.
23. Lieschke, G.J. & Burgess, A.W. (1992) Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor. New England Journal of Medicine, 327, 99-106.
24. Matsunaga, T., Sakamaki, S., Kohgo, Y., Ohi, S., Hirayama, Y. & Niitsu, Y. (1993) Recombinant human granulocyte colony-stimulating factor can mobilize sufficient amounts of peripheral blood stem cells in healthy volunteers for allogeneic transplantation. Bone Marrow Transplantation, 11, 103-108.
25. 3H-thymidine incorporation are related to position of thymidine residues in oligodeoxy-nucleotides. Experimental Hematology, 22, 384-387.
26. Nimer, S.D. (1992) The use of colony-stimulating factors in primary hematologic disorders. Cancer, 70, 921-927.
27. Otto, F.J. (1990) Preparation and staining of cells for high-resolution DNA analysis. Methods in Cell Biology (ed. by Z. Darzynkiewicz and H. A. Crissman), p. 105. Academic Press, San Diego.
28. Pollack, A. & Ciancio, G. (1990) Cell cycle phase-specific analysis of cell viability using Hoechst 33342 and propidium iodide after ethanol preservation. Methods in Cell Biology (ed. by Z. Darzynkiewicz and H. A. Crissman), p. 19. Academic Press, San Diego.
29. Rice, A., Boiron, J.M., Barbot, C., Dupouy, M., Dubsoc-Marchenay, N., Dumain, P., Lacombe, F. & Reiffers, J. (1994) Cytokine-mediated expansion of 5-FU resistant peripheral blood stem cells and bone marrow: self-renewal and commitment capacity. Journal of Hematotherapy, 3, 135-139.
30. Russell, N.H., Hunter, A., Rogers, A., Hanley, J. & Anderson, D. (1993) Peripheral blood stem cells as an alternative to marrow for allogeneic transplantation. Lancet, 341, 1482.
31. Schwinger, W., Mache, C., Urban, C., Beaufort, F. & Töglhofer, W. (1993) Single dose of filgrastim (rhG-CSF) increases the number of hematopoietic progenitors in the peripheral blood of adult volunteers. Bone Marrow Transplantation, 11, 489-492.
32. Sheridan, W.P., Begley, C.G., Juttner, C.A., Szer, J., To, L.B., Maher, D., McGrath, K.M., Morstyn, G. & Fox, R.M. (1992) Effect of peripheral-blood progenitor cells mobilized by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet, 339, 640-644.
33. Singer, J.W. (1992) Role of colony-stimulating factors in bone marrow transplantation. Seminars in Oncology, 19, 27-31.
34. + marrow cells. Experimental Hematology, 19, 734-741.
35. + normal human hematopoietic cells. Blood, 82, 2069-2078.
36. + cells. Blood, 84, 2930-2939.
37. To, L.B., Roberts, M., Haylock, D.M., Dyson, P.G., Branford, A.L., Thorp, D., Ho, J.Q.K., Dart, G.W., Hovarth, N., Davy, M.L.J., Olweny, C.L.M., Abdi, E. & Juttner, C.A. (1992) Comparison of haematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants. Bone Marrow Transplantation, 9, 277-284.
38. + cells an enhanced ex vivo expansion potential. Experimental Hematology, 22, 1264-1272.
39. Vadhan-Raj, S., Broxmeyer, H.E., Hittelman, W.N., Papadopulos, N.E., Chawla, S.P., Feneglio, C., Cooper, S., Buescher, E.S., Frenck, R.W., Holian, A., Perkins, R.C., Scheule, R.K., Gutterman, J.U., Salem, P. & Benjamin, R.S. (1992) Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: protection at the progenitor cell level. Journal of Clinical Oncology, 10, 1266-1277.
40. + subsets in growth factor mobilized apheresis products from normal subjects. (Abstract). Annals of Hematology, 68, A39.