Activity of voriconazole, a new triazole, combined with neutrophils or monocytes against Candida albicans: Effect of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 4, 1998, Pages 907-910

  Vora, Shefali ^a   Purimetla, Nayanatara ^a   Brummer, Elmer ^a,b,c   Stevens, David A ^a,b  

^a CALIFORNIA INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SANTA CLARA VALLEY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; FLUCONAZOLE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; TRIAZOLE DERIVATIVE; VORICONAZOLE;

ARTICLE; CANDIDA ALBICANS; CANDIDIASIS; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG POTENTIATION; FUNGICIDAL ACTIVITY; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL;

EID: 0031979179     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.4.907     Document Type: Article

References (12)

1. Ansari, A. M., I. M. Gould, and J. G. Douglas. 1990. High dose oral fluconazole for oropharyngeal candidiasis in AIDS. J. Antimicrob. Chemother. 25:720-721.
2. Barry, A. L., and S. D. Brown. 1996. In vitro studies of two triazole antifungal agents (voriconazole [UK-109,496] and fluconazole) against Candida species. Antimicrob. Agents Chemother. 40:1948-1949.
3. Bodey, G. P. 1966. Fungal infections complicating acute leukemia. J. Chronic Dis. 19:667-687.
4. Brummer, E., and D. A. Stevens. 1996. Synergy of human neutrophils with fluconazole in killing Candida species. Mycopathologia 134:115-120.
5. Garcha, U. K., E. Brummer, and D. A. Stevens. 1995. Synergy of fluconazole with human monocytes or monocyte-derived macrophages for killing Candida species. J. Infect. Dis. 172:1620-1623.
6. Gujral, S., E. Brummer, and D. A. Stevens. 1996. Role of extended culture time on synergy of fluconazole and human monocyte-derived macrophages in clearing Candida albicans. J. Infect. Dis. 174:888-889.
7. Klein, R. S., C. A. Harris, C. B. Small, B. Moll, M. Lesser, and G. H. Friedland. 1984. Oral candidiasis in high risk patients as the initial manifestations of the acquired immune deficiency syndrome. N. Engl. J. Med. 311: 354-356.
8. Natarajan, U., E. Brummer, and D. A. Stevens. 1997. Effect of granulocyte colony-stimulating factor on the candidacidal activity of polymorphonuclear neutrophils and their collaboration with fluconazole. Antimicrob. Agents Chemother. 41:1575-1578.
9. Natarajan, U., N. Randhawa, E. Brummer, and D. A. Stevens. Effect of granulocyte macrophage-colony stimulating factor on candidacidal activity of neutrophils, monocytes or monocyte-derived macrophages and synergy with fluconazole. J. Med. Microbiol., in press.
10. Sanguineti, A., K. Carmichael, and K. Campbell. 1993. Fluconazole resistant Candida albicans after long term suppressive therapy. Arch. Intern. Med. 153:1122-1124.
11. Schroter, G. P. J., M. Hoelscher, C. W. Putman, K. A. Porter, and T. E. Starzl. 1977. Fungus infections after liver transplantation. Ann. Surg. 186: 115-122.
12. Winston, D. J., R. P. Gale, D. V. Meyer, and L. S. Young. 1979. Infectious complications in human marrow transplantation. Medicine 58:1-31.