Synergy of human neutrophils with fluconazole in killing Candida species

Mycopathologia

Volumn 134, Issue 3, 1996, Pages 115-120

  Brummer, Elmer ^a   Stevens, David A ^b  

^a SANTA CLARA VALLEY MEDICAL CENTER   (United States)

^b NONE

Author keywords

candidacidal; fluconazole; neutrophils; synergy

Indexed keywords

EID: 0030443864     PISSN: 0301486X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00436717     Document Type: Article

References (17)

1. Bodey GP. Fungal infections complicating acute leukemia. J Chron Dis 1966; 19: 667-687.
2. Winston DJ, Gale RP, Meyer DV, Young LS. Infectious complications of human marrow transplantation. Medicine 1979; 58: 1-31.
3. Schroter GPJ, Hoelscher M, Putman CW, Porter KA, Starzl TE. Fungus infections after liver transplantation. Ann Surg 1977; 186: 115-122.
4. Klein RS, Harris CA, Small CB, Moll B, Lesser M, Friedland GH. Oral candidiasis in high risk patients as the initial manifestation of the acquired immunodeficiency syndrome. N Eng J Med 1984; 311: 354-356.
5. Ellis M, Gupta S, Galant S, Hakin S, VandeVen C, Toy C, Cairo MS. Impaired neutrophil function in patients with AIDS or AIDS-related complex: a comprehensive evaluation. J Infect Dis 1988; 158: 1268-1276.
6. Ansari AM, Gould IM, Douglas JG. High dose oral fluconazole for oropharyngeal candidiasis in AIDS. J Antimicrobial Chemother 1990; 25: 720-721.
7. Rogers TE, Galgiani JN. Activity of fluconazole (UK 49858) and ketoconazole against Candida albicans in vitro and in vivo. Antimicrob Agents Chemother 1986; 30: 418-422.
8. Lehrer RI. Measurement of candidacidal activity of specific leukocyte types in mixed cell populations. I. Normal, myeloperoxidase-deficient, and chronic granulomatous disease neutrophils. Infect Immun 1970; 2: 42-47.
9. Sohnle PG, Collins-Lech C. Comparison of candidacidal and candidastatic activities of human neutrophils. Infect Immun 1990; 58: 2696-2698.
10. Fromtling RA, Galgiani JN, Pfaller MA, Espinel-Ingroff A, Bartizal KF, Bartlett MS, Body BA, Frey C, Hall G, Roberts GD, Nolte FB, Odds FC, Rinaldi MG, Sugar AM, Villareal K. Multicenter evaluation of broth macrodilution antifungal susceptibility test for yeasts. Antimicrob Agents Chemother 1993; 37: 39-45.
11. Brummer E, Stevens DA. Opposite effects of human monocytes, macrophages, and polymorphonuclear neutrophils on replication of Blastomyces dermatitidis in vitro. Infect Immun 1982; 36: 297-303.
12. Glanz SA, Slinker BK (eds.). Primer of Applied Regression and Analysis of Variance. 1st edn. New York: McGraw-Hill, 1990.
13. Georgopapadakou NH, Walsh TJ. Human mycoses: drugs and targets for emerging pathogens. Science 1994; 264: 371-372.
14. Wildfeuer A, Laufen H, Haferkamp O. Interaction of fluconazole and human phagocytic cells. Arzneimittel-Forsch Drug Res 1990; 40: 1044-1047.
15. Sugar AM, Tjia J. Effect of fluconazole on the interactions between human neutrophils and Candida albicans, Int J Antimicrob Agents 1993; 3: 171-173.
16. Roilides E, Walsh TJ, Rubin M, Venzon D, Pizzo PA. Effects of antifungal agents on the function of human neutrophils in vitro. Antimicrob Agents Chemother 1990; 34: 196-201.
17. Odds FC, Webster CE. Effects of azole antifungals in vitro on host/parasite interactions relevant to Candida infections. J Antimicrob Chemother 1988; 22: 473-481.