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Volumn 62, Issue 5, 1998, Pages 364-370

Myocardial uptake of iodine-125-labeled 15-(P-Iodophenyl)-3-(R,S)- methyl pentadecanoic acid is decreased in chronic diabetic rats with changes in subcellular distribution

Author keywords

Diabetes mellitus; Fatty acid metabolism; Iodine 125 1abeled 15 (p iodophenyl) 3 (R,S) methyl pentadecanoic acid (125I BMIPP); Mitochondria; Myocardium

Indexed keywords

15 (4 IODOPHENYL)PENTADECANOIC ACID; IODINE 125;

EID: 0031978911     PISSN: 00471828     EISSN: None     Source Type: Journal    
DOI: 10.1253/jcj.62.364     Document Type: Article
Times cited : (2)

References (47)
  • 1
    • 0003082107 scopus 로고
    • Fuels. Carbohydrates and lipitis
    • Opie LH, editor. New York: Raven Press
    • Opie LH: Fuels. Carbohydrates and lipitis. In: Opie LH, editor. The heart. Physiology and metabolism, 2nd edn. New York: Raven Press, 1991: 208-246
    • (1991) The Heart. Physiology and Metabolism, 2nd Edn. , pp. 208-246
    • Opie, L.H.1
  • 3
    • 0023032822 scopus 로고
    • Iodine-123-phenylpentadecanoic acid myocardial scintigraphy usefulness in the identification of myocardial ischemia
    • Kennedy PL, Corbett JR, Kulkarni PV, Wolfe CL, Jansen DE, Hansen CL, et al: Iodine-123-phenylpentadecanoic acid myocardial scintigraphy usefulness in the identification of myocardial ischemia. Circulation 1986; 74: 1007-1015
    • (1986) Circulation , vol.74 , pp. 1007-1015
    • Kennedy, P.L.1    Corbett, J.R.2    Kulkarni, P.V.3    Wolfe, C.L.4    Jansen, D.E.5    Hansen, C.L.6
  • 4
    • 0025202230 scopus 로고
    • Radioiodinated fatty acid scintigraphy of the normal human myocardium during exercise testing: A new interpretation
    • Visser FC, Van Eenige MJ, Duwel CMB, Van Lingen A, Roos JP: Radioiodinated fatty acid scintigraphy of the normal human myocardium during exercise testing: a new interpretation. NucCompact 1990; 21: 236-240
    • (1990) NucCompact , vol.21 , pp. 236-240
    • Visser, F.C.1    Van Eenige, M.J.2    Duwel, C.M.B.3    Van Lingen, A.4    Roos, J.P.5
  • 5
    • 0025818166 scopus 로고
    • Demonstration of disturbed free fatty acid metabolism of myocardium in patients with non-insulin-dependent diabetes mellitus as measured with iodine-123-heptadecanoic acid
    • Kuikka JT, Mustonen JN, Uusitupa MIJ, Rautio P, Vanninen E, Laakso E, et al: Demonstration of disturbed free fatty acid metabolism of myocardium in patients with non-insulin-dependent diabetes mellitus as measured with iodine-123-heptadecanoic acid. Eur J Nucl Med 1991; 18: 475-481
    • (1991) Eur J Nucl Med , vol.18 , pp. 475-481
    • Kuikka, J.T.1    Mustonen, J.N.2    Uusitupa, M.I.J.3    Rautio, P.4    Vanninen, E.5    Laakso, E.6
  • 6
    • 0026648266 scopus 로고
    • Regional metabolic abnormality in relation to perfusion and wall motion in patients with myocardial infarction: Assessment with emission tomography using an iodinated branched fatty acid analog
    • Tamaki N, Kawamoto M, Yonekura Y, Fujibayashi Y, Takahashi N, Konishi J, et al: Regional metabolic abnormality in relation to perfusion and wall motion in patients with myocardial infarction: assessment with emission tomography using an iodinated branched fatty acid analog. J Nacl Med 1992; 33: 659-667
    • (1992) J Nacl Med , vol.33 , pp. 659-667
    • Tamaki, N.1    Kawamoto, M.2    Yonekura, Y.3    Fujibayashi, Y.4    Takahashi, N.5    Konishi, J.6
  • 7
    • 0029041654 scopus 로고
    • Cardiac SPECT with iodine123-labeled fatty acids: Evaluation of myocardial viability with BMIPP
    • Knapp Jr. FR, Franken P, Kropp J: Cardiac SPECT with iodine123-labeled fatty acids: evaluation of myocardial viability with BMIPP. J Nucl Med 1995; 36: 1022-1030
    • (1995) J Nucl Med , vol.36 , pp. 1022-1030
    • Knapp Jr., F.R.1    Franken, P.2    Kropp, J.3
  • 8
    • 0026557282 scopus 로고
    • Myocardial emission computed tomography with iodine-123-labeled beta-methyl-branched fatty acid in patients with hypertrophic cardiomyopathy
    • Kurata C, Tawarahara K, Taguchi T, Aoshima S, Kobayashi A, Yamazaki N, et al: Myocardial emission computed tomography with iodine-123-labeled beta-methyl-branched fatty acid in patients with hypertrophic cardiomyopathy. J Nucl Med 1992; 33: 6-13
    • (1992) J Nucl Med , vol.33 , pp. 6-13
    • Kurata, C.1    Tawarahara, K.2    Taguchi, T.3    Aoshima, S.4    Kobayashi, A.5    Yamazaki, N.6
  • 9
    • 0028990752 scopus 로고
    • 123I-beta-methyl-iodophenyl-pentadecanoic acid myocardial scintigraphy in diabetic patients without overt ischemic heart disease
    • 123I-beta-methyl-iodophenyl-pentadecanoic acid myocardial scintigraphy in diabetic patients without overt ischemic heart disease (in Japanese, abstract in English). J Cardiol 1995; 26: 23-32
    • (1995) J Cardiol , vol.26 , pp. 23-32
    • Shinmura, K.1    Tani, M.2    Suganuma, Y.3    Hasegawa, H.4    Kawamura, M.5    Nakamura, Y.6
  • 10
    • 0028327412 scopus 로고
    • Simultaneous dual myocardial imaging with iodine-123-beta-methyl iodophenyl-pentadecanoic acid (BMIPP) and thallium-201 in patients with coronary heart disease
    • Tawarahara K, Kurata C, Taguchi T, Aoshima S, Okayama K, Kobayashi A, et al: Simultaneous dual myocardial imaging with iodine-123-beta-methyl iodophenyl-pentadecanoic acid (BMIPP) and thallium-201 in patients with coronary heart disease. Jpn Circ J 1994; 58: 107-115
    • (1994) Jpn Circ J , vol.58 , pp. 107-115
    • Tawarahara, K.1    Kurata, C.2    Taguchi, T.3    Aoshima, S.4    Okayama, K.5    Kobayashi, A.6
  • 11
    • 0023018835 scopus 로고
    • New radioiodinated methyl-branched fatty acid for cardiac studies
    • Knapp Jr. FF, Ambrose KR, Goodman MM: New radioiodinated methyl-branched fatty acid for cardiac studies. Eur J Nucl Med 1986; 12: S39-S44
    • (1986) Eur J Nucl Med , vol.12
    • Knapp Jr., F.F.1    Ambrose, K.R.2    Goodman, M.M.3
  • 12
    • 0023102470 scopus 로고
    • Evaluation of the metabolism in rat hearts of two new radioiodinated 3-methyl-branched fatty acid myocardial imaging agents
    • Ambrose KR, Owen BA, Goodman MM, Knapp Jr FK: Evaluation of the metabolism in rat hearts of two new radioiodinated 3-methyl-branched fatty acid myocardial imaging agents. Eur J Nucl Med 1987; 12: 486-491
    • (1987) Eur J Nucl Med , vol.12 , pp. 486-491
    • Ambrose, K.R.1    Owen, B.A.2    Goodman, M.M.3    Knapp Jr., F.K.4
  • 13
    • 0028871488 scopus 로고
    • Planar myocardial imaging in the baboon model with iodine-123-15-(iodophenyl) pentadenanoic acid (IPPA) and iodine-123-15-(p-iodophenyl)-3-R,S-methylpentadenanoic acid (BMIPP), using time - Activity curves for evaluation of metabolism
    • Dormehl IC, Hugo N, Rossouw D, White A, Feinendegen LE: Planar myocardial imaging in the baboon model with iodine-123-15-(iodophenyl) pentadenanoic acid (IPPA) and iodine-123-15-(p-iodophenyl)-3-R,S-methylpentadenanoic acid (BMIPP), using time - activity curves for evaluation of metabolism. Nucl Med Biol 1995; 22: 837-847
    • (1995) Nucl Med Biol , vol.22 , pp. 837-847
    • Dormehl, I.C.1    Hugo, N.2    Rossouw, D.3    White, A.4    Feinendegen, L.E.5
  • 16
    • 0023909525 scopus 로고
    • Myocardial fuel and energy balance, acute ischemia and diabetes
    • McDaniel HG, Jenkins RL, Digerness SB: Myocardial fuel and energy balance, acute ischemia and diabetes. Am J Med Sci 1988: 295: 207-211
    • (1988) Am J Med Sci , vol.295 , pp. 207-211
    • McDaniel, H.G.1    Jenkins, R.L.2    Digerness, S.B.3
  • 17
    • 0026486495 scopus 로고
    • Paradoxical role of lipid metabolism in heart function and dysfunction
    • Dhalla NS, Elimban V, Rupp H: Paradoxical role of lipid metabolism in heart function and dysfunction. Mol Cell Biochem 1992; 116: 3-9
    • (1992) Mol Cell Biochem , vol.116 , pp. 3-9
    • Dhalla, N.S.1    Elimban, V.2    Rupp, H.3
  • 18
    • 0028949410 scopus 로고
    • Myocardial substrate metabolism: Implications for diabetic cardiomyopathy
    • Rodrigues B, Cam MC, McNeill JH: Myocardial substrate metabolism: implications for diabetic cardiomyopathy. J Mal Cell Cardiol 1995; 27: 169-179
    • (1995) J Mal Cell Cardiol , vol.27 , pp. 169-179
    • Rodrigues, B.1    Cam, M.C.2    McNeill, J.H.3
  • 19
    • 0024325441 scopus 로고
    • Diabetic cardiomyopathy
    • Zarich SW, Nesto RW: Diabetic cardiomyopathy. Am Heart J 1989; 118: 1000-1012
    • (1989) Am Heart J , vol.118 , pp. 1000-1012
    • Zarich, S.W.1    Nesto, R.W.2
  • 20
    • 0029060453 scopus 로고
    • Diabetic cardiomyopathy: A unique entity or a complication of coronary artery disease?
    • Bell DSH: Diabetic cardiomyopathy: a unique entity or a complication of coronary artery disease? Diabetes Care 1995; 18: 708-714
    • (1995) Diabetes Care , vol.18 , pp. 708-714
    • Bell, D.S.H.1
  • 21
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J, Lees M, Stanley GHS: A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 1957; 226: 497-509
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Stanley, G.H.S.3
  • 22
    • 0028819065 scopus 로고
    • Cardiac glucose and fatty acid oxidation in the streptozotocin-induced diabetic spontaneously hypertensive rat
    • Christe ME, Rodgers RL: Cardiac glucose and fatty acid oxidation in the streptozotocin-induced diabetic spontaneously hypertensive rat. Hypertension 1995; 25: 235-241
    • (1995) Hypertension , vol.25 , pp. 235-241
    • Christe, M.E.1    Rodgers, R.L.2
  • 23
    • 3042895173 scopus 로고
    • Altered uptake and kinetics of radioiodinated 15-p-(I-125)-iodophenyl-3-methylpentadecanoic acid in diabetic myocardium
    • Van der Wall EE, Barrett E, Straus HW, Lange R, Elmaleh D, Zaret BL, et al: Altered uptake and kinetics of radioiodinated 15-p-(I-125)-iodophenyl-3-methylpentadecanoic acid in diabetic myocardium (abstract). Circulation 1985; 72: III-424
    • (1985) Circulation , vol.72
    • Van Der Wall, E.E.1    Barrett, E.2    Straus, H.W.3    Lange, R.4    Elmaleh, D.5    Zaret, B.L.6
  • 24
    • 0023473474 scopus 로고
    • Metabolism of palmitate in isolated working hearts from spontaneously diabetic "BB" wistar rats
    • Lopaschuk GD, Tsang H: Metabolism of palmitate in isolated working hearts from spontaneously diabetic "BB" wistar rats. Circ Res 1987; 61: 853-858
    • (1987) Circ Res , vol.61 , pp. 853-858
    • Lopaschuk, G.D.1    Tsang, H.2
  • 25
    • 0001670650 scopus 로고
    • The role of altered lipid metabolism in the cardiac dysfunction associated with diabetes
    • Nagano M, Dhalla NS, editors. New York: Raven Press
    • Paulson DJ, Shug AL, Jurak R, Schmidt: The role of altered lipid metabolism in the cardiac dysfunction associated with diabetes. In: Nagano M, Dhalla NS, editors. The diabetic heart. New York: Raven Press, 1991: 395-407
    • (1991) The Diabetic Heart , pp. 395-407
    • Paulson, D.J.1    Shug, A.L.2    Jurak, R.3    Schmidt4
  • 26
    • 3043003472 scopus 로고
    • Glucose and palmitate oxidation during reperfusion of ischemic hearts from diabetic rats
    • Nagano M, Dhalla NS, editors. New York: Raven Press
    • Lopaschuk GD, Spafford MA: Glucose and palmitate oxidation during reperfusion of ischemic hearts from diabetic rats. In: Nagano M, Dhalla NS, editors. The diabetic heart. New York: Raven Press, 1991: 451-464
    • (1991) The Diabetic Heart , pp. 451-464
    • Lopaschuk, G.D.1    Spafford, M.A.2
  • 28
    • 0026085762 scopus 로고
    • Beta-oxidation of fatty acids
    • Schulz H: Beta-oxidation of fatty acids. Biochim Biophys Acta 1991; 1081: 109-120
    • (1991) Biochim Biophys Acta , vol.1081 , pp. 109-120
    • Schulz, H.1
  • 30
    • 3042964909 scopus 로고
    • Lipoprotein lipase activity in isolated perfused hearts of streptozotocin-induced diabetic rats
    • Nagano M, Dhalla NS, editors. New York: Raven Press
    • Murase T, Mochizuki S, Yamaoka H, Nagano M: Lipoprotein lipase activity in isolated perfused hearts of streptozotocin-induced diabetic rats. In: Nagano M, Dhalla NS, editors. The diabetic heart. New York: Raven Press, 1991: 409-413
    • (1991) The Diabetic Heart , pp. 409-413
    • Murase, T.1    Mochizuki, S.2    Yamaoka, H.3    Nagano, M.4
  • 31
    • 0024477852 scopus 로고
    • 125I-BMIPP in rats treated with adriamycin
    • 125I-BMIPP in rats treated with adriamycin (in Japanese, Abstract in English). Jpn J Nucl Med 1989; 26: 69-76
    • (1989) Jpn J Nucl Med , vol.26 , pp. 69-76
    • Ogata, M.1
  • 32
    • 85047678466 scopus 로고
    • Mitochondrial dysfunction observed in situ in cardiomyocytes of rats in experimental diabetes
    • Tanaka Y, Konno N, Kako KJ: Mitochondrial dysfunction observed in situ in cardiomyocytes of rats in experimental diabetes. Cardiovasc Res 1992; 26: 409-414
    • (1992) Cardiovasc Res , vol.26 , pp. 409-414
    • Tanaka, Y.1    Konno, N.2    Kako, K.J.3
  • 33
    • 0021968297 scopus 로고
    • Mitochondrial abnormalities in diabetic cardiomyopathy
    • Pierce GN, Dhalla NS: Mitochondrial abnormalities in diabetic cardiomyopathy. Can J Cardiol 1985; 1: 48 -55
    • (1985) Can J Cardiol , vol.1 , pp. 48-55
    • Pierce, G.N.1    Dhalla, N.S.2
  • 34
    • 0021921144 scopus 로고
    • Oxidative metabolism of Polytron vs Nagarse mitochondria in hearts of genetically diabetic mice
    • Kuo TH, Giacomelli F, Wiener J: Oxidative metabolism of Polytron vs Nagarse mitochondria in hearts of genetically diabetic mice. Biochim Biophys Acta 1985; 806: 9-15
    • (1985) Biochim Biophys Acta , vol.806 , pp. 9-15
    • Kuo, T.H.1    Giacomelli, F.2    Wiener, J.3
  • 35
    • 0023279695 scopus 로고
    • Competition between fatty acids and carbohydrate or ketone bodies as metabolic fuels for the isolated perfused heart
    • Forsey RG, Reid K, Brosnan JT: Competition between fatty acids and carbohydrate or ketone bodies as metabolic fuels for the isolated perfused heart. Can J Physiol Pharmacol 1987; 65: 401-406
    • (1987) Can J Physiol Pharmacol , vol.65 , pp. 401-406
    • Forsey, R.G.1    Reid, K.2    Brosnan, J.T.3
  • 36
    • 0020146576 scopus 로고
    • Endogenous triacylglycerol metabolism in diabetic heart
    • Paulson DJ, Crass MF III: Endogenous triacylglycerol metabolism in diabetic heart. Am J Physiol 1982; 142: H1084-H1094
    • (1982) Am J Physiol , vol.142
    • Paulson, D.J.1    Crass III, M.F.2
  • 37
    • 3043003473 scopus 로고
    • Effect of ischemia and reperfusion on lipid metabolism and glycogenolysis in hearts from normal and diabetic rats
    • Nagano M, Dhalla NS, editors. New York: Raven Press
    • Griffiths EJ, Lloyd AJ, Brunt RV: Effect of ischemia and reperfusion on lipid metabolism and glycogenolysis in hearts from normal and diabetic rats. In: Nagano M, Dhalla NS, editors. The diabetic heart. New York: Raven Press, 1991: 441 -449
    • (1991) The Diabetic Heart , pp. 441-449
    • Griffiths, E.J.1    Lloyd, A.J.2    Brunt, R.V.3
  • 38
    • 0025153028 scopus 로고
    • Myocardial accumulation of iodinated beta-methyl-branched fatty acid analogue, iodine-125-15-(p-iodophenyl)-3-(R,S) methylpentadecanoic acid (BMIPP), in relation to ATP concentration
    • Fujibayashi Y, Yonekura Y, Takemura Y, Wada K, Matsumoto K, Tamaki N, et al: Myocardial accumulation of iodinated beta-methyl-branched fatty acid analogue, iodine-125-15-(p-iodophenyl)-3-(R,S) methylpentadecanoic acid (BMIPP), in relation to ATP concentration. J Nucl Med 1990; 31: 1818-1822
    • (1990) J Nucl Med , vol.31 , pp. 1818-1822
    • Fujibayashi, Y.1    Yonekura, Y.2    Takemura, Y.3    Wada, K.4    Matsumoto, K.5    Tamaki, N.6
  • 39
    • 0027486343 scopus 로고
    • Malonyl-CoA metabolism in cardiac myocyte and its relevance to the control of fatty acid oxidation
    • Awan MM, Saggerson ED: Malonyl-CoA metabolism in cardiac myocyte and its relevance to the control of fatty acid oxidation. Biochem J 1993; 295: 61 -66
    • (1993) Biochem J , vol.295 , pp. 61-66
    • Awan, M.M.1    Saggerson, E.D.2
  • 40
    • 0028522881 scopus 로고
    • Acetyl-CoA carboxylase. An important regulator of fatty acid oxidation in the heart
    • Lopaschuk GD, Gamble J: Acetyl-CoA carboxylase. An important regulator of fatty acid oxidation in the heart. Can J Physiol Pharmacol 1994; 72: 1101-1109
    • (1994) Can J Physiol Pharmacol , vol.72 , pp. 1101-1109
    • Lopaschuk, G.D.1    Gamble, J.2
  • 41
    • 0018575357 scopus 로고
    • Effect of streptozotocin on carnitine and carnitine acyl transferase in rat heart, liver, kidney
    • Fogle PJ, Beiber LL: Effect of streptozotocin on carnitine and carnitine acyl transferase in rat heart, liver, kidney. Biochem Med 1979; 22: 119-126
    • (1979) Biochem Med , vol.22 , pp. 119-126
    • Fogle, P.J.1    Beiber, L.L.2
  • 42
    • 0027724861 scopus 로고
    • Changes in the subcellular distribution of free carnitine and its acyl derivatives in diabetic rat hearts following treatment with L-carnitine
    • Aoshima S, Fujisawa S, Kobayashi A: Changes in the subcellular distribution of free carnitine and its acyl derivatives in diabetic rat hearts following treatment with L-carnitine. Jpn Heart J 1993; 34: 763-772
    • (1993) Jpn Heart J , vol.34 , pp. 763-772
    • Aoshima, S.1    Fujisawa, S.2    Kobayashi, A.3
  • 43
    • 0020170579 scopus 로고
    • A mechanism of reduced myocardiai carnitine levels in diabetic animals
    • Vary TC, Neely JR: A mechanism of reduced myocardiai carnitine levels in diabetic animals. Am J Physiol 1982; 243: H154-H158
    • (1982) Am J Physiol , vol.243
    • Vary, T.C.1    Neely, J.R.2
  • 45
    • 0028985792 scopus 로고
    • Fundamental limitations of (18F)2-deoxy-2-fluoro-D-glucose for assessing myocardiai glucose uptake
    • Hariharan R, Bray M, Ganim R, Doenst T, Goodwin GW, Taegtmeyer H: Fundamental limitations of (18F)2-deoxy-2-fluoro-D-glucose for assessing myocardiai glucose uptake. Circulation 1995; 91: 2435-2444
    • (1995) Circulation , vol.91 , pp. 2435-2444
    • Hariharan, R.1    Bray, M.2    Ganim, R.3    Doenst, T.4    Goodwin, G.W.5    Taegtmeyer, H.6
  • 46
    • 0028350243 scopus 로고
    • Quantitative analysis of myocardiai structure in insulin-dependent diabetes mellitus: Effects of immediate and delayed insulin replacement
    • Thompson EW: Quantitative analysis of myocardiai structure in insulin-dependent diabetes mellitus: effects of immediate and delayed insulin replacement. Proc Soe Exp Biol Med 1994; 205: 294-305
    • (1994) Proc Soe Exp Biol Med , vol.205 , pp. 294-305
    • Thompson, E.W.1
  • 47
    • 0023801526 scopus 로고
    • Fatty acid analogue accumulation: A marker of myocyte viability in ischemic-reperfused myocardium
    • Miller DD, Gill JB, Livni E, Elmaleh DR, Aretz T, Boucher CA, et al: Fatty acid analogue accumulation: a marker of myocyte viability in ischemic-reperfused myocardium. Circ Res 1988; 63: 681-692
    • (1988) Circ Res , vol.63 , pp. 681-692
    • Miller, D.D.1    Gill, J.B.2    Livni, E.3    Elmaleh, D.R.4    Aretz, T.5    Boucher, C.A.6


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