Apathy and hypersomnia are common features of myotonic dystrophy

Journal of Neurology Neurosurgery and Psychiatry

Volumn 64, Issue 4, 1998, Pages 510-515

  Rubinsztein, J S ^a   Rubinsztein, D C ^b   Goodburn, S ^b   Holland, A J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Apathy; Hypersomnia; Major depression; Myotonic dystrophy

Indexed keywords

ADULT; AGED; APATHY; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; FEMALE; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HYPERSOMNIA; MALE; MENTAL DISEASE; MUSCLE WEAKNESS; MYOTONIA; MYOTONIC DYSTROPHY; PRIORITY JOURNAL; QUALITY OF LIFE; SYMPTOM;

EID: 0031977854     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.64.4.510     Document Type: Article

References (45)

1. Wieringa B. Commentary: myotonic dystrophy reviewed: back to the future? Hum Mol Genet 1994;3:1-7.
2. Hunter A, Tsilfidis C, Mettler G, et al. The correlation of age of onset with CTG trinucleotide repeat amplification in myotonic dystrophy. J Med Genet 1992;29:774-9.
3. Harper PS. Myotonic dystrophy. London: WB Saunders, 1979.
4. Rosman NP, Kakulas BA. Mental deficiency associated with myotonic dystrophy: a neuropathological study. Brain 1966;89:769-87.
5. Culebras A, Feldman RG, Meak FB. Cytoplasmic inclusion bodies within neurones of the thalamus in myotonic dystrophy. A light and electron microsopic study. J Neurol Sci 1973;19:319-29.
6. Wisniewski HM, Berry K, Spiro AJ. Ultrastructure of the thalamic neuronal inclusions in myotonic dystrophy. J Neurol Sci 1975;24:321-9.
7. Ono S, Inoue K, Mannen T, et al. Neuropathological changes in the brain in myotonic dystrophy: some new observations. J Neurol Sci 1987;81:301-20.
8. Oyanagi K, Ogawa H, Nakajima T. Rod-like intracytoplasmic inclusions in large neurons of the caudate nucleus in frequent appearance in myotonic dystrophy. Clin Neuropathol 1994;13:134-8.
9. Avrahami E, Katz A, Bornstein N, et al. Computed tomographic findings of brain and skull in myotonic dystrophy J Neurol Neurosurg Psychiatry 1987;50:435-8.
10. Glantz RH, Wright RB, Hackman MS, et al. Central nervous system magnetic imaging findings in myotonic dystrophy. Arch Neurol 1988;45:36-8.
11. Abe K, Fujimura H, Toyooka K, et al. Involvement of the central nervous system in myotonic dystrophy. J Neurol Sci 1994;127:179-85.
12. Huber SJ, Kissel JT, Shuttleworth EC, et al. Magnetic resonance imaging and clinical correlates of intellectual impairment in myotonic dystrophy. Arch Neurol 1989;46:536-40.
13. Chang L, Anderon T, Migneco OA, et al. Cerebral abnormalities in myotonic dystrophy: cerebral blood flow, magnetic imaging and neuropsychological tests. Arch Neurol 1993;50:917-23.
14. Fiorelli M, Duboc D, Mazoyer BM, et al. Decreased cerebral glucose utilisation in myotonic dystrophy. Neurology 1992;42:91-4.
15. Harper PS. Congenital myotonic dystrophy in Britain. Arch Dis Child 1975;50:505-13.
16. Turnpenny P, Clark C, Kelly K. Intelligence quotient profile in myotonic dystrophy, intergenerational deficit and correlations with CTG amplifications. J Med Genet 1994;31:300-5.
17. Rubinsztein JS, Rubinsztein DC, McKenna PJ, et al. Mild myotonic dystrophy is associated with memory impairment in the context of normal general intelligence. J Med Genet 1997;3:229-33.
18. Bird TD, Follett C, Griep E. Cognitive and personality function in myotonic dystrophy. J Neurol Neurosurg Psychiatry 1983;46:971-80.
19. Ambrosini PJ, Nurnberg HG. Psychopathology: a primary feature of myotonic dystrophy. Psychosomatics 1979;20: 393-9.
20. Palmer BW, Boone KB, Chang L, et al. Cognitive deficits in personality patterns in maternally versus paternally inherited myotonic dystrophy. J Clin Exp Neuropsychol 1994;16: 784-95.
21. Brumback RA, Carlson KM. Psychiatric disorder in myotonia [letter]. Biol Psychol 1983;18:603.
22. Caughey JE, Myrianthopoulos NC. Dystrophia myotonica and related disorders. Springfield Ill: Charles C Thomas, 1963.
23. Marin RS. Apathy: a neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci 1991;3:243-54.
24. Van der Meche FGA, Bogaard JM, van der Sluys RJ, et al. Daytime sleep in myotonic dystrophy is not caused by sleep apnoea. J Neurol Neurosurg Psychiatry 1994;57:626-8.
25. Brumback RA, Carlson KM, Wilson H, et al. Med Hypotheses 1981;7:1059-6.
26. Raeymackers P, Timmerman V, Nelis E, et al. Duplication in chromosome 17p 11.2 in Charcot Marie Tooth neuropathy type 1a (CMT 1a). Neuromuscul Disord 1991;1:93-7.
27. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 1991;14:540-5.
28. Marin RS, Biedrzycki RC, Firinciogullari S. Reliability and validity of the apathy evaluation scale. Psychiatry Res 1991 38:143-62.
29. Wessely S, Powell R. Fatigue syndromes: a comparison of chronic "postviral" fatigue with neuromuscular and affective disorders. J Neurol Neurosurg Psychiatry 1989;52:940-8.
30. Endicott J, Spitzer RL. A diagnostic interview - the schedule for affective disorders and schizophrenia. Arch Gen Psychology 1978;35:837-44.
31. Nelson HE. The national adult reading test (NART). Windsor: NFER- Nelson, 1982.
32. Medical Research Council of the UK. Aids to the examination of the peripheral nervous system. Palo Alto: Pendragon House, 1978.
33. Harley HG, Rundle SA, MacMillan JC, et al. Size of the unstable CTG repeat sequence in relation to phenotype and parental transmission in myotonic dystrophy. Am J Hum Genet 1993;52:1164-74.
34. Thorpy MJ. International classification of sleep disorders. Diagnostic and coding manual. Diagnostic Classification Steering Committee. Rochester, MN: American Sleep Disorders Association, 1990.
35. Weissman MM, Myers JK. Affective disorders in a US urban community. Arch Gen Psychiatry 1978;35:1304-11.
36. Parkes JD. Sleep and its disorders. Philadelphia: WB Saunders, 1985.
37. Guilleminault C. Disorders of excessive sleepiness. Annals of Clinical Research 1985;17:209-219.
38. Woodward JB, Heaton RK, Simon DB, et al. J Clin Neuropsychology 1982;4:335-42.
39. Censori B, Danni M, DelPesce M, et al. Neuropsychological profile in myotonic dystrophy. J Neurol 1990;237:251-6.
40. Malloy P, Mishra SK, Adler SH. Neuropsychological deficits in myotonic dystrophy. J Neurol Neurosurg Psychiatry 1990;53:1011-3.
41. Nelson HE. A modified card sorting test to frontal defects. Cortex 1976;12:313-24
42. Shallice T, Evans ME. The involvement of the frontal lobes in cognitive estimation. Cortex 1978;14:294-303.
43. Starkstein SE, Mayberg HS, Preziosi TJ, et al. Reliability, validity and clinical correlates of apathy in Parkinson's disease. J Neuropsychialry Clin Neurosci 1992;4:134-9.
44. Starkstein SE, Federoff JP, Price TR, et al. Apathy following cerebrovascular lesions. Stroke 1993;24:1625-30.
45. Rolls ET. Connections, functions and dysfunctions of limbic structures, the prefrontal cortex and hypothalamus. In: M Swash, C Kennard eds. Scientific basis of neurology. Edinburgh: Churchill Livingstone, 1985:201-13.