Mild myotonic dystrophy is associated with memory impairment in the context of normal general intelligence

Journal of Medical Genetics

Volumn 34, Issue 3, 1997, Pages 229-233

  Rubinsztein, J S ^a   Rubinsztein, D C ^b   McKenna, P J ^c   Goodburn, S ^b   Holland, A J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

^c FULBOURN HOSPITAL   (United Kingdom)

Author keywords

Intelligence; Memory and executive function; Myotonic dystrophy; Trinucleotide repeat

Indexed keywords

REPETITIVE DNA;

AMNESIA; ARTICLE; CLINICAL ARTICLE; COGNITION; DISEASE SEVERITY; HUMAN; INTELLIGENCE; MYOTONIC DYSTROPHY; PRIORITY JOURNAL; TRINUCLEOTIDE REPEAT;

EID: 0031029789     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.34.3.229     Document Type: Article

References (17)

1. Wieringa B. Commentary. Myotonic dystrophy is reviewed: back to the future? Hum Mol Genet 1994;3:1-7.
2. Hunter A, Tsilfidas C, Mettler G, et al. The correlation of age of onset with CTG trinucleotide repeat amplification in myotonic dystrophy. J Med Genet 1992;29:774-9.
3. Harley HG, Rundle SA, MacMillan JC, et al. Size of the unstable CTG repeat sequence in relation to phenotype and parental transmission in myotonic dystrophy. Am J Hum Genet 1993;52:1164-74.
4. Harper PS. Congenital myotonic dystrophy in Britain. Arch Dis Child 1975;50:505-15.
5. Woodward JB, Heaton RK, Simon DB, Ringel SP. Neuropsychological findings in myotonic dystrophy. J Clin Neuropsychol 1982;4:335-42.
6. Portwood MM, Wicks JJ, Lieberman JAS, Duveneck MJ. Intellectual and cognitive function in adults with myotonic muscular dystrophy. Arch Phys Med Rehabil 1986;67:299-303.
7. Chang L, Anderson T, Migneco OA, et al. Cerebral abnormalities in myotonic dystrophy. Arch Neurol 1993;50:917-23.
8. Medical Research Council of the UK. Aids to the examination of the peripheral nervous system. Palo Alto: Pendragon House, 1978.
9. Nelson HE. The national adult reading test (NART). Windsor: NFER-Nelson, 1982.
10. Raven JC. Guide to the standard progressive matrices. London: Lewis and Co, 1960.
11. Folstein MF, Folstein SE, McHugh PR. "Mini-Mental State". A practical method for grading the cognitive state of patients for the clinician. J Psychol Res 1975;12:189-98.
12. Wilson BC J, Baddeley A, Hiorns R. The development and validation of a test battery for detecting and monitoring everyday memory problems. J Clin Exp Neuropsychol 1989; 11:855-70.
13. Shallice T, Burgess PW, Frith CD. Can the neuropsychological case study approach be applied to schizophrenia. Psychol Med 1991;21:661-73.
14. Nelson HE. A modified card sorting test to frontal lobe defects. Cortex 1976;12:313-24.
15. Shallice T, Evans ME. The involvement of the frontal lobes in cognitive estimation. Cortex 1978;14:294-303.
16. Lezak MD. Neuropsychological assessment. 2nd ed. Oxford: Oxford University Press, 1983.
17. Bird TD, Follett C, Griep E. Cognitive and personality function in myotonic muscular dystrophy. J Neurol Neurosurg Psychiatry 1983;46:971-80.