Activated pulmonary macrophages are insufficient for resistance against Pneumocystis carinii

Infection and Immunity

Volumn 66, Issue 1, 1998, Pages 305-314

  Hanano, Ralph ^a,b   Reifenberg, Kurt ^a,b   Kaufmann, Stefan H E ^b  

^a Department of Immunology ^*

^b UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANNOSE RECEPTOR; MESSENGER RNA; NITRIC OXIDE; SUPEROXIDE; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HOST RESISTANCE; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; MOUSE MUTANT; NONHUMAN; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL;

EID: 0031975958     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.1.305-314.1998     Document Type: Article

References (53)

1. Abe, E., Y. Ishimi, H. Tanaka, C. Miyaura, H. Nagasawa, T. Harashi, and T. Suda. 1986. The relationship between fusion and proliferation in mouse alveolar macrophages. Endocrinology 121:271-277.
2. Beck, J. M., H. D. Liggitt, E. N. Bninnette, H. J. Fuchs, J. E. Shcllito, and R. J. Debs. 1991. Reduction in intensity of Pneumocyslis carinii pneumonia in mice by aerosol administration of gamma interferon. Infect. Immun. 59:3859-3862.
3. Bendelac, A., M. N. Rivera, S.-H. Park, and J. H. Roark. 1997. Mouse CD1-specific NK cells: development, specificity, function. Annu. Rev. Immunol. 15:535-562.
4. Celada, A., and C. Nathan. 1994. Macrophage activation revisited. Immunol. Today 15:100-102.
5. Chen, W., E. A. Havell, and A. G. Harmsen. 1992. Importance of endogenous tumor necrosis factor alpha and gamma interferon in host resistance against Pneumocystu carinii infection. Infect. Immun. 60:1279-1284.
6. Chen, W., E. A. Havell, L. L. Moldawer, K. W. McIntyre, R. A. Chizzonite, and A. G. Harmsen. 1992. Interleukin 1: an important mediator of host resistance against Pneumocyslis carinii. J. Exp. Med. 176:713-718.
7. Cosgrove, D., D. Gray, A. Dierich, J. Kaufman, L. Lemeur, C. Benoist, and D. Mathis. 1991. Mice lacking MHC class II molecules. Cell 66:1051-1066.
8. Cushion, M. T., J. R. Stringer, and P. D. Walzer. 1991. Cellular and molecular biology of Pneumocystis carinii. Int. Rev. Cytol. 131:59-107.
9. Daugelat, S., and S. H. E. Kaufmann. 1996. Role of Th1 and Th2 cells in bacterial infections. Chem. Immunol. 63:66-97.
10. Dinarello, C. A. 1992. Role of interleukin-1 in infectious diseases. Immunol. Rev. 127:119-146.
11. Ezekowitz, R. A. B., D. J. Williams, H. Koziel, M. Y. K. Armstrong, F. F. Richards, and R. M. Rose. 1993. Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor. Nature 351:155-158.
12. Flesch, I. E. A., J. H. Hess, and S. H. E. Kaufmann. 1994. NADPH diaphorase staining suggests a transient and localized contribution of nitric oxide to host defence against an intracellular pathogen in situ. Int. Immunol. 6:1751-1757.
13. Flyun, J. L., M. M. Goldstein, J. Chan, K. J. Triebold, K. Pfeffer, C. J. Lowenstein, R. Schreiber, T. W. Mak, and B. R. Bloom. 1995. Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 2:561-572.
14. Gany, B., R. A. B. Ezekowitz, and A. G. Harmsen. 1997. Role of gamma interferon in the host immune and inflammatory responses to Pneumocystis carinii infection. Infect. Immun. 65:373-379.
15. Gigliotti, F., B. Gany, and A. G. Harmsen. 1996. Antibody-mediated shift in the profile of glycoprotein A phenotypes observed in a mouse model of Pneumocystis carinii pneumonia. Infect. Immun. 64:1892-1899.
16. Gigliotti, F., and W. T. Hughes. 1988. Passive immunoprophylaxis with specific mAb confers partial protection against Pneumocystis carinii pneumonia in animal models. J. Clin. Invest. 81:1666-1668.
17. 15N nitrate in biological fluids. Anal. Biochem. 126:131-138.
18. Hanano, R., and S. H. E. Kaufmann. 1995. Nitric oxide production and mycobacterial growth inhibition by murine alveolar macrophages: the sequence of rIFN-γ stimulation and Mycobacterium bovis BCG infection determines macrophage activation. Immunol. Lett. 45:23-27.
19. Hanano, R., K. Reifenberg, and S. H. E. Kaufmann. 1996. T- and B-Iymphocyte-independent formation of alveolar macrophage-derived multinucleated giant cells in murine Pneumocystis carinii pneumonia. Infect. Immun. 64:2821-2823.
20. Hanano, R., K. Reifenberg, and S. H. E. Kaufmann. 1996. Naturally acquired Pneumocystis carinii pneumonia in gene disruption mutant mice: role of distinct T-cell populations in infection. Infect. Immun. 64:3201-3209.
21. Harmsen, A. G., W. Chen, and F. Gigliotti. 1995. Active immunity to Pneumocystis carinii reinfection in T-cell-depleted mice. Infect. Immun. 63:2391-2395.
22. + T cells in resistance to Pneumocystis carinii pneumonia in mice. J. Exp. Med. 172:937-945.
23. Hogg, N., V. M. Darley-Usmar, M. T. Wilson, and S. Moncada. 1992. Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide. Biochem. J. 281:419-424.
24. Huang, S., W. Hendriks, A. Althage, S. Hemmi, H. Bluethmann, R. Kamijo, J. Vilcek, R. M. Zinkernagel, and M. Aguet. 1993. Immune responses in mice that lack the interferon-γ receptor. Science 259:1742-1745.
25. Koziel, H., D. O'Riordan, A. Warner, and R. M. Rose. 1994. Alveolar macrophage interaction with Pneumocystis carinii, p. 417-436. In B. S. Zwilling and T. K. Eisenstein (ed.), Macrophage-pathogen interactions-1994. Marcel Dekker Inc., New York, N.Y.
26. Krakauer, T., and J. J. Oppenheim. 1993. IL-1 and tumor necrosis factor each upregulate both the expression of IFN-γ receptors and enhance IFN-γ-induced HLA-DR expression on human monocytes and a human monocytic cell line (THP-1). J. Immunol. 150:1205-1211.
27. Krieger, M., and J. Herz. 1994. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptorrelated protein (LRP). Annu. Rev. Biochem. 63:601-637.
28. Lament, A. G., and L. Adorini. 1996. IL-12: a key cytokine in immune regulation. Immunol. Today 17:214-217.
29. Lipton, S. A., Y.-B. Choi, Z.-H. Pan, S. Z. Lei, H.-S. V. Chen, N. J. Sucher, J. Loscalzo, D. J. Singel, and J. S. Stamler. 1993. A redox-based mechanism for neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 364:626-632.
30. MacMicking, J., Q.-W. Xie, and C. Nathan. 1997. Nitric oxide and macrophage function. Annu. Rev. Immunol. 15:323-350.
31. Mazer, M. A., J. A. Kovacs, J. C. Swan, J. E. Parrillo, and H. Masur. 1987. Histoenzymological study of selected dehydrogenase enzymes in Pneumocystis carinii. Infect. Immun. 55:727-730.
32. Mombaerts, P., A. R. Clarke, M. L. Hooper, and S. Tonegawa. 1991. Creation of a large genomic deletion at the T-cell antigen receptor β-subunit locus in mouse embryonic stem cells by gene targeting. Proc. Natl. Acad. Sci. USA 88:3084-3087.
33. Mombaerts, P., J. lacomini, R. S. Johnson, S. Tonegawa, and V. E. Papa-ioannou. 1992. RAG-1 deficient mice have no mature T and B lymphocytes. Cell 68:869-877.
34. Murray, II. W., B. Y. Rubin, H. Masur, and R. B. Roberts. 1984. Impaired production and lymphokines of immune (gamma) intcrferon in the acquired immunodeficiency syndrome. N. Engl. J. Med. 310:883-889.
35. Murray, J. F., S. M. Garay, P. C. Hopewell, J. Mills, G. L. Snider, and D. E. Stover. 1987. NHBLI Workshop summary. Complications of the acquired immunodeficiency syndrome: an update. Am. Rev. Respir. Dis. 135:504-509.
36. Naito, M., T. Kodama, A. Matsumoto, T. Doi, and K. Takahashi. 1991. Tissue distribution, intracellular localization, and in vitro expression of bovine macrophage scavenger receptors. Am. J. Pathol. 139:1411-1423.
37. O'Riordan, D. M., J. E. Standing, and A. H. Limper. 1995. Pneumocystis carinii glycoprotein A binds macrophage mannosc receptors. Infect. Immun. 63:779-784.
38. O'Riordan, D. M., J. E. Standing, K.-Y. Kwon, D. Chang, E. C. Crouch, and A. II. Limper. 1995. Surfactant protein D interacts with Pneumocystis carinii and mediates organism adherence to alveolar macrophages. J. Clin. Invest. 95:2699-2710.
39. Pearson, A. M. 1996. Scavenger receptors in innate immunity. Curr. Opin. Immunol. 8:20-28.
40. Persson, A., D. Chang, K. Rust, M. Moxley, W. Longmore, and E. Crouch. Purification and biochemical characterization of CP4 (SP-D): a collagenous surfactant-associated protein. Biochemistry 27:6361-6367.
41. Phair, J., A. Munoz, R. Betels, R. Kaslow, C. Rinaldo, A. Saah, and the Multicentre AIDS Cohort Study Group. 1990. The risk of Pneumocystis carinii pneumonia among men infected with human immunodeficiency virus typ I. N. Engl. J. Med. 322:161-165.
42. Rothc, J., W. Lesslauer, H. Lutscher, Y. Lang, P. Kocbel, F. Königen, A. Althage, R. Zinkcrnagel, M. Steinmetz, and II. Bluethmann. 1993. Mice lacking the tumor necrosis factor receptor 1 are resistant to TNF-mcdiatcd toxicity but highly susceptible to infection by Lisicria monocylogenes. Nature 364:798-802.
43. + T cells into severe combined immunodeficiency mice. J. Clin. Invest. 90:673-678.
44. Roths, J. B., and C. L. Sidman. 1993. Single and combined humoral and cell-mediated immunotherapy of Pneumocysiis carinii pneumonia in immunodeficient seid mice. Infect. Immun. 61:1641-1649.
45. Shear, H. L., G. Valladares, and M. A. Narachi. 1990. Enhanced treatment of Pneumocysiis carinii pneumonia in rats with interferon-γ and reduced doses of trimethoprim/sulphamethoxazole. J. Acquired Immun. Defie. Syndr. 3:943-948.
46. Shellito, J., V. V. Suzura, W. Blumenfeld, J. M. Beck, H. J. Steger, and T. H. Ermak. 1990. A new model of Pneumocysiis carinii infection in mice selectively depleted of helper T lymphocytes. J. Clin. Invest. 85:1686-1693.
47. Shellito, J. E., J. K. Kolls, R. Olariu, and J. M. Beck. 1996. Nitric oxide and host defense against Pneumocysiis carinii infection in a mouse model. J. Infect. Dis. 173:432-439.
48. Sherman, M. P., M. L. Loro, V. Z. Wong, and D. P. Tashkin. 1991. Cytokineand Pneumocysiis carinii-induced L-arginine oxidation by murine and human pulmonary alveolar macrophages. J. Protozool. 38:2345-2365.
49. Sherman, M. P., II. A. Hidalgo, E. E. Aeberhard, V. Z. Wong, M. B. Gilliam, and R. J. Helmke. 1992. Pneumocysiis carinii and interferon gamma induce rat alveolar macrophages to produce nitric oxide. Am. Rev. Rcspir. Dis. 145:A246.
50. Trinchicri, G. 1995. Interleukin-12: a proinfiammatory cytokine with immunorcgulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annu. Rev. Immunol. 13:251-276.
51. Voorhout, W. F. T., T. Veenendaal, Y. Kuroki, Y. Ogasawara, L. M. van Golde, and H. J. Geuze. 1992. Immunohistochemical localization of surfactant protein D (SP-D) in type II cells, Clara cells, and alveolar macrophages or rat lung. J. Histochem. Cytochem. 40:1589-1597.
52. Wakefield, A. E., F. J. Pixlcy, S. Banerji, K. Sinclair, R. F. Miller, E. R. Moxon, and J. M. Hopkin. 1990. Detection of Pneiimocystis carinii with DNA amplification. Lancet 336:451-453.
53. Walzer, P. D. 1991. Immunopathogcnisis of Pneiimocystis carinii infection. J. Lab. Clin. Med. 118:206-216.