메뉴 건너뛰기




Volumn 70, Issue 5, 1998, Pages 1964-1972

RGS7 attenuates signal transduction through the G(αq) family of heterotrimeric G proteins in mammalian cells

Author keywords

GTPase activating protein; Heterotrimeric G protein; RGS protein; Serotonin receptors

Indexed keywords

COMPLEMENTARY DNA; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; RECOMBINANT PROTEIN;

EID: 0031969802     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70051964.x     Document Type: Article
Times cited : (55)

References (25)
  • 1
    • 0024412926 scopus 로고
    • Beta-adrenergic receptor kinase: Primary structure delineates a multigene family
    • Benovic J. L., DeBlasi A., Stone W. C., Caron M. G., and Lefkowitz R. J. (1989) Beta-adrenergic receptor kinase: primary structure delineates a multigene family. Science 246, 235-240.
    • (1989) Science , vol.246 , pp. 235-240
    • Benovic, J.L.1    DeBlasi, A.2    Stone, W.C.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 2
    • 0030576518 scopus 로고    scopus 로고
    • GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits
    • Berman D. M., Wilkie T. M., and Gilman A. G. (1996a) GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits. Cell 86, 445-452.
    • (1996) Cell , vol.86 , pp. 445-452
    • Berman, D.M.1    Wilkie, T.M.2    Gilman, A.G.3
  • 3
    • 0029861417 scopus 로고    scopus 로고
    • The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis
    • Berman D. M., Kozasa T., and Gilman A. G. (1996b) The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis. J. Biol. Chem. 271, 27209-27212.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27209-27212
    • Berman, D.M.1    Kozasa, T.2    Gilman, A.G.3
  • 4
    • 0030931829 scopus 로고    scopus 로고
    • Simultaneous expression of multi-subunit proteins in mammalian cells using a convenient set of mammalian cell expression vectors
    • Cockett M. I., Ochalski R., Benwell K., Franco R., and Wardwell-Swanson J. (1997) Simultaneous expression of multi-subunit proteins in mammalian cells using a convenient set of mammalian cell expression vectors. Biotechniques 23, 402-405.
    • (1997) Biotechniques , vol.23 , pp. 402-405
    • Cockett, M.I.1    Ochalski, R.2    Benwell, K.3    Franco, R.4    Wardwell-Swanson, J.5
  • 5
    • 0029559788 scopus 로고
    • GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits
    • De Vries L., Mousli M., Wurmser A., and Farquhar M. G. (1995) GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits. Proc. Natl. Acad. Sci. USA 92, 11916-11920.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11916-11920
    • De Vries, L.1    Mousli, M.2    Wurmser, A.3    Farquhar, M.G.4
  • 6
    • 0029767982 scopus 로고    scopus 로고
    • Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: Expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit)
    • Dohlman H. G., Song J., Ma D., Courchesne W. E., and Thorner J. (1996) Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Mol. Cell. Biol. 16, 5194-5209.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5194-5209
    • Dohlman, H.G.1    Song, J.2    Ma, D.3    Courchesne, W.E.4    Thorner, J.5
  • 7
    • 0030029727 scopus 로고    scopus 로고
    • Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family
    • Druey K. M., Blumer K. J., Kang V. H., and Kehrl J. H. (1996) Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family. Nature 379, 742-746.
    • (1996) Nature , vol.379 , pp. 742-746
    • Druey, K.M.1    Blumer, K.J.2    Kang, V.H.3    Kehrl, J.H.4
  • 8
    • 0029761351 scopus 로고    scopus 로고
    • Pharmacological characterization of a Chinese hamster ovary cell line transfected with the human CCK-B receptor gene
    • Dunlop J., Brammer N., and Ennis C. (1996) Pharmacological characterization of a Chinese hamster ovary cell line transfected with the human CCK-B receptor gene. Neuropeptides 30, 359-363.
    • (1996) Neuropeptides , vol.30 , pp. 359-363
    • Dunlop, J.1    Brammer, N.2    Ennis, C.3
  • 9
    • 0024432232 scopus 로고
    • Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400
    • Furuichi T., Yoshikawa S., Miyawaki A., Wada K., Maeda N., and Mikoshiba K. (1989) Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400. Nature 342, 32-38.
    • (1989) Nature , vol.342 , pp. 32-38
    • Furuichi, T.1    Yoshikawa, S.2    Miyawaki, A.3    Wada, K.4    Maeda, N.5    Mikoshiba, K.6
  • 10
    • 0029670065 scopus 로고    scopus 로고
    • Characterization of a 5-HT1B receptor on CHO cells: Functional responses in the absence of radioligand binding
    • Giles H., Lansdell S. J., Bolofo M.-L., Wilson H. L., and Martin G. R. (1996) Characterization of a 5-HT1B receptor on CHO cells: functional responses in the absence of radioligand binding. Br. J. Pharmacol. 117, 1119-1126.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 1119-1126
    • Giles, H.1    Lansdell, S.J.2    Bolofo, M.-L.3    Wilson, H.L.4    Martin, G.R.5
  • 11
    • 0030764226 scopus 로고    scopus 로고
    • Regulator of G protein signaling (RGS) proteins: Region-specific expression of nine subtypes in rat brain
    • Gold S. J., Yan Y. G., Dohlman H. G., and Nestler E. J. (1997) Regulator of G protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain. J. Neurosci. 17, 8024-8037.
    • (1997) J. Neurosci. , vol.17 , pp. 8024-8037
    • Gold, S.J.1    Yan, Y.G.2    Dohlman, H.G.3    Nestler, E.J.4
  • 13
    • 0031017573 scopus 로고    scopus 로고
    • RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha
    • Hepler J. R., Berman D. M., Gilman A. G., and Kozasa T. (1997) RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha. Proc. Natl. Acad. Sci. USA 94, 428-432.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 428-432
    • Hepler, J.R.1    Berman, D.M.2    Gilman, A.G.3    Kozasa, T.4
  • 14
    • 0030610240 scopus 로고    scopus 로고
    • Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells
    • Huang C., Hepler J. R., Gilman A. G., and Mumby S. (1997) Attenuation of Gi- and Gq-mediated signaling by expression of RGS4 or GAIP in mammalian cells. Proc. Natl. Acad. Sci. USA 94, 6159-6163.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6159-6163
    • Huang, C.1    Hepler, J.R.2    Gilman, A.G.3    Mumby, S.4
  • 15
    • 0029830014 scopus 로고    scopus 로고
    • RGS10 is a selective activator of G alpha i GTPase activity
    • Hunt T. W., Fields T. A., Casey P. J., and Peralta E. G. (1996) RGS10 is a selective activator of G alpha i GTPase activity. Nature 383, 175-177.
    • (1996) Nature , vol.383 , pp. 175-177
    • Hunt, T.W.1    Fields, T.A.2    Casey, P.J.3    Peralta, E.G.4
  • 16
    • 0028260220 scopus 로고
    • Functionally active targeting domain of the beta-adrenergic receptor kinase: An inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase
    • Inglese J., Luttrell L. M., Iniguez-Lluhi J. A., Touhara K., Koch W. J., and Lefkowitz R. J. (1994) Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase. Proc. Natl. Acad. Sci. USA 91, 3637-3641.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3637-3641
    • Inglese, J.1    Luttrell, L.M.2    Iniguez-Lluhi, J.A.3    Touhara, K.4    Koch, W.J.5    Lefkowitz, R.J.6
  • 17
    • 0030032001 scopus 로고    scopus 로고
    • EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins
    • Koelle M. R. and Horvitz H. R. (1996) EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Cell 84, 115-125.
    • (1996) Cell , vol.84 , pp. 115-125
    • Koelle, M.R.1    Horvitz, H.R.2
  • 18
    • 0031053536 scopus 로고    scopus 로고
    • Potential role for a regulator of G protein signaling (RGS3) in gonadotropin-releasing hormone (GnRH) stimulated desensitization
    • Neill J. D., Duck L. W., Sellers J. C., Musgrove L. C., Scheschonka A., Druey K. M., and Kehrl J. H. (1997) Potential role for a regulator of G protein signaling (RGS3) in gonadotropin-releasing hormone (GnRH) stimulated desensitization. Endocrinology 138, 843-846.
    • (1997) Endocrinology , vol.138 , pp. 843-846
    • Neill, J.D.1    Duck, L.W.2    Sellers, J.C.3    Musgrove, L.C.4    Scheschonka, A.5    Druey, K.M.6    Kehrl, J.H.7
  • 19
    • 0028920668 scopus 로고
    • Protein kinases that phosphorylate activated G protein-coupled receptors
    • Premont R. T., Inglese J., and Lefkowitz R. J. (1995) Protein kinases that phosphorylate activated G protein-coupled receptors. FASEB J. 9, 175-182.
    • (1995) FASEB J. , vol.9 , pp. 175-182
    • Premont, R.T.1    Inglese, J.2    Lefkowitz, R.J.3
  • 21
    • 0023276837 scopus 로고
    • Primary structure of the human beta-adrenergic receptor gene
    • Schofield P. R., Rhee L. M., and Peralta E. G. (1987) Primary structure of the human beta-adrenergic receptor gene. Nucleic Acids Res. 15, 3636.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 3636
    • Schofield, P.R.1    Rhee, L.M.2    Peralta, E.G.3
  • 22
    • 0030982264 scopus 로고    scopus 로고
    • Structure of RGS4 bound to AlF4-activated G(i alpha 1): Stabilization of the transition state for GTP hydrolysis
    • Tesmer J. J. G., Berman D. M., Gilman A. G., and Sprang S. R. (1997) Structure of RGS4 bound to AlF4-activated G(i alpha 1): stabilization of the transition state for GTP hydrolysis. Cell 89, 251-261.
    • (1997) Cell , vol.89 , pp. 251-261
    • Tesmer, J.J.G.1    Berman, D.M.2    Gilman, A.G.3    Sprang, S.R.4
  • 23
    • 0027995423 scopus 로고
    • Hypothalamic paraventricular, but not supraoptic neurons, mediate the serotonergic stimulation of oxytocin secretion
    • Van de Kar L. D., Rittenhouse P. A., Li Q., Levy A. D., and Brownfield M. S. (1995) Hypothalamic paraventricular, but not supraoptic neurons, mediate the serotonergic stimulation of oxytocin secretion. Brain Res. Bull. 36, 45-50.
    • (1995) Brain Res. Bull. , vol.36 , pp. 45-50
    • Van De Kar, L.D.1    Rittenhouse, P.A.2    Li, Q.3    Levy, A.D.4    Brownfield, M.S.5
  • 24
    • 0029808079 scopus 로고    scopus 로고
    • RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits
    • Watson N., Linder M. E., Druey K. M., Kehrl J. H., and Blumer K. J. (1996) RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits. Nature 383, 172-175.
    • (1996) Nature , vol.383 , pp. 172-175
    • Watson, N.1    Linder, M.E.2    Druey, K.M.3    Kehrl, J.H.4    Blumer, K.J.5
  • 25
    • 0029790622 scopus 로고    scopus 로고
    • The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development
    • Yu J.-H., Wieser J., and Adams T. H. (1996) The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow development. EMBO J. 15, 5184-5190.
    • (1996) EMBO J. , vol.15 , pp. 5184-5190
    • Yu, J.-H.1    Wieser, J.2    Adams, T.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.