Image analysis of the morphology of filamentous micro-organisms

Microbiology

Volumn 144, Issue 4, 1998, Pages 817-827

  Cox, P W ^a   Paul, G C ^a   Thomas, C R ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Actinomycetes; Differentiation; Fungi; Image analysis; Morphology

Indexed keywords

ACTINOMYCES; CELL STRUCTURE; FUNGUS SPORE; IMAGE ANALYSIS; MYCELIUM; NONHUMAN; PRIORITY JOURNAL; REVIEW; YEAST;

ACTINOBACTERIA (CLASS); ACTINOMYCES; FUNGI;

EID: 0031967694     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-144-4-817     Document Type: Review

References (68)

1. Adams, H. L. & Thomas, C. R. (1988). The use of image analysis for morphological measurements on filamentous microorganisms. Biotechnol Bioeng 32, 707-712.
2. Agger, T., Spohr, A. B., Carlsen, M. & Nielsen, J. (1998). Growth and product formation of Aspergillus oryzae during submerged cultivations: verification of a morphologically structured model using fluorescent probes. Biotechnol Bioeng 57, 321-329.
3. Belmar-Beiny, M. T. & Thomas, C. R. (1991). Morphology and clavulanic acid production of Streptomyces clavuligerus: effect of stirrer speed in batch fermentations. Biotechnol Bioeng 37, 456-462.
4. Clarke, D. S. (1962). Submerged citric acid fermentation of ferro-cyanide treated beet molasses: morphology of pellets of Aspergillus niger. Can J Microbiol 8, 133-136.
5. Cox, P. W. & Thomas, C. R. (1992). Classification and measurement of fungal pellets by automated image analysis. Biotechnol Bioeng 39, 945-952.
6. Czymmek, K. J., Whallon, J. H. & Klomparens, K. L. (1994). Confocal microscopy in mycological research. Exp Mycol 18, 275-293.
7. Donnelly, D. P. & Boddy, L. (1997). Development of mycelial systems of Stroplaria caerulea and Phanerochaete velutina on soil: effect of temperature and water potential. Mycol Res 101, 705-713.
8. Donnelly, D. P., Wilkins, M. F. & Boddy, L. (1995). An integrated image analysis approach for determining biomass, radial extent and box-count fractal dimension of macroscopic mycelial systems. Binary 7, 19-28.
9. Drouin, J. F., Louvel, L., Vanhoutte, B., Vivier, H., Pons, M. N. & Germain, P. (1997). Quantitative characterisation of cellular differentiation of Streptomyces ambofaciens in submerged culture by image analysis. Biotechnol Tech 11, 819-824.
10. Durant, G., Crawly, G. & Formysyn, P. (1994a). A simple staining procedure for characterisation of basidiomycete pellets by image analysis. Biotechnol Tech 8, 395-400.
11. Durant, G., Cox, P. W., Formysyn, P. & Thomas, C. R. (1994b). Improved image analysis algorithm for the characterisation of mycelial aggregates after staining. Biotechnol Tech 8, 759-764.
12. Gow, N. A. R. (1994). Tip growth and polarity. In The Growing Fungus, pp. 227-300. Edited by N. A. R. Gow & G. M. Gadd. London: Chapman & Hall.
13. Green, D. C., Vilariño, A., Newsam, R., Jeffries, P. & Dodd, J. C. (1994). Quantification of mycelial development of arbuscular mycorrhizal fungi using image analysis. Mycorrhiza 5, 105-113.
14. Gull, K. & Trinci, A. P. J. (1974). Detection of areas of wall differentiation in fungi using fluorescent staining. Arch Microbiol 96, 53-57.
15. Jeenes, D. J., MacKenzie, D. A., Roberts, I. N. & Archer, D. B. (1991). Heterologous protein production by filamentous fungi. Biotechnol Genet Rev 9, 327-367.
16. Jones, C. L., Lonergan, G. T. & Mainwaring, D. E. (1995). Acid phosphatase positional correlations in solid surface fungal cultivation: a fractal interpretation of biochemical differentiation. Biochem Biophys Res Commun 208, 1159-1165.
17. Jüsten, P., Paul, G. C. & Thomas, C. R. (1994). Fixation technique to preserve the vacuolation of Penicillium chrysogenum hyphae. Biotechnol Tech 8, 853-858.
18. Jüsten, P., Paul, G. C., Nienow, A. W. & Thomas, C. R. (1996). Dependence of mycelial morphology on impeller type and agitation intensity. Biotechnol Bioeng 52, 672-684.
19. Kron, S. J., Styles, C. A. & Fink, G. R. (1994). Symmetrical cell division in pseudohyphae of the yeast Saccharomyces cerevisiae. Mol Biol Cell 5, 1003-1022.
20. Lendenfeld, T., Ghali, D., Wolschek, M., Kubiceckpranz, E. M. & Kubicek, C. P. (1993). Subcellular compartmentalization of penicillin biosynthesis in Penicillium chrysogenum: the amino acid precursors are derived from the vacuole. J Biol Chem 268, 665-671.
21. Li, S., Spear, R. H. & Andrews, J. H. (1997). Quantitative fluorescence in situ hybridization of Aureobasidium pullulans on microscope slides and leaf surfaces. Appl Environ Microbiol 63, 3260-3267.
22. MacKenzie, D. A., Jeenes, D. J., Belshaw, H. J. & Archer, D. B. (1993). Regulation of secreted protein production by filamentous fungi: recent developments and perspectives. J Gen Microbiol 139, 2295-2307.
23. McNeil, B., Berry, D. R., Harvey, L. M., Grant, A. & White, S. (1998). Measurement of autolysis in submerged batch cultures of Penicillium chrysogenum. Biotechnol Bioeng 57, 297-305.
24. Martin, S. M. & Bushell, M. E. (1996). Effect of hyphal micromorphology on bioreactor performance of antibiotic-producing Saccharopolyspora erythraea cultures. Microbiology 142, 1783-1788.
25. Mauss, P., Drouin, J. F., Pons, M. N., Vivier, H., Germain, P., Louvel, L. & Vanhoutte, B. (1997). Localisation of respiratory activity in filamentous bacteria by image analysis. Biotechnol Tech 11, 813-817.
26. Megee, R. D., Kinishita, S., Fredrickson, A. G. & Tsuchiya, H. M. (1970). Differentiation and product formation in molds. Biotechnol Bioeng 12, 771-801.
27. Merson-Davies, L. A. & Odds, F. C. (1992). Expansion of the Candida albicans cell envelope in different morphological forms of the fungus. J Gen Microbiol 138, 461-466.
28. Metz, B. (1976). From pulp to pellets: an engineering study of the morphology of moulds. PhD thesis, Delft Technical University.
29. Müller, W. H., Bovenberg, R. A. L., Groothuis, M. H., Kattevilder, F., Smaal, E. B., Vandervoot, L. H. M. & Verkeij, A. J. (1992). Involvement of microbodies in penicillin biosynthesis. Biochim Biophys Acta 116, 210-213.
30. Nestaas, E. & Wang, D. I. C. (1983). Computer control of penicillin fermentation using filtration probe in conjunction with a structured process model. Biotechnol Bioeng 25, 781-796.
31. Nielsen, J. & Krabben, P. (1995). Hyphal growth and fragmentation of Penicillium chrysogenum in submerged cultures. Biotechnol Bioeng 46, 588-598.
32. Nielsen, J., Johansen, C. L., Jacobsen, M., Krabben, P. & Villadsen, J. (1995). Pellet formation and fragmentation in submerged cultures of Penicillium chrysogenum and its relation to penicillin production. Biotechnol Prog 11, 93-98.
33. Oh, K. B., Chen, Y. L., Mutsuoka, H., Yamamoto, A. & Kurata, H. (1996). Morphological recognition of fungal spore germination by computer aided image analysis and its application to antifungal activity evaluation. J Biotechnol 45, 71-79.
34. Olsson, S. (1994). Uptake of glucose and phosphorus by growing colonies of Fusarium oxysporum as quantified by image analysis. Exp Mycol 18, 33-47.
35. Olsvik, E., Tucker, K. G., Thomas, C. R. & Kristiansen, B. (1993). Correlation of Aspergillus niger broth rheological properties with biomass concentration and shape. Biotechnol Bioeng 42, 1046-1052.
36. O'Shea, D. G. & Walsh, P. K. (1996). Morphological characterisation of the dimorphic yeast Kluyveromyces marxianus var marxianus NRRL Y2415 by semi-automatic image analysis. Biotechnol Bioeng 51, 679-690.
37. Packer, H. L. & Thomas, C. R. (1990). Morphological measurement on filamentous microorganisms by fully automatic image analysis. Biotechnol Bioeng 35, 870-881.
38. Paul, G. C. & Thomas, C. R. (1996). A structured model for hyphal differentiation and penicillin production using Penicillium chrysogenum. Biotechnol Bioeng 51, 558-572.
39. Paul, G. C. & Thomas, C. R. (1998). Characterisation of mycelial morphology using image analysis. Adv Biochem Eng Biotechnol 60, 1-59.
40. Paul, G. C., Kent, C. A. & Thomas, C. R. (1992). Quantitative characterization of vacuolization in Penicillium chrysogenum using automatic image analysis. Trans IChemE (part C) 70, 13-20.
41. Paul, G. C., Kent, C. A. & Thomas, C. R. (1993). Viability testing and characterisation of germination of fungal spores by automatic image analysis. Biotechnol Bioeng 42, 11-23.
42. Paul, G. C., Kent, C. A. & Thomas, C. R. (1994a). Hyphal vacuolation and fragmentation in Penicillium chrysogenum. Biotechnol Bioeng 44, 655-660.
43. Paul, G. C., Kent, C. A. & Thomas, C. R. (1994b). Image analysis for characterising differentiation of Penicillium chrysogenum. Trans IChemE (part C) 72, 95-105.
44. Peberdy, J. F. (1994). Protein secretion in filamentous fungi -trying to understand a highly productive black box. Trends Biotechnol 12, 50-57.
45. Pichon, D., Vivier, H. & Pons, M. N. (1993). Growth monitoring of filamentous microorganisms by image analysis. In Modelling and Control of Biotechnological Processes 1992, pp. 307-309. Edited by N. M. Karim & G. Stephanopoulos. Oxford: Pergamon.
46. Pons, M. N., Vivier, H., Remy, J. F. & Dodds, J. A. (1993). Morphological characterisation of yeast by image analysis. Biotechnol Bioeng 42, 1352-1359.
47. Pons, M. N., Vivier, H., Pichon, D. & Dronin, J. F. (1997). Morphological characterization of fermentation broths. In Abstracts of the 8th European Congress on Biotechnology, abstract MO173. Budapest: Magyar Biokémiai Egyesület.
48. Regnaga-Peña, C. G., Gierz, G. & Bartnicki-Garcia, S. (1997). Analysis of the role of the Spitzenkörper in fungal morphogenesis by computer simulation of apical branching in Aspergillus niger. Proc Natl Acad Sci USA 94, 9096-9101.
49. Reichl, U., Bushult, T. K. & Gilles, E. D. (1990). Study of the early growth and branching of Streptomyces tendae by means of an image processing system. J Microsc 158, 55-62.
50. Reichl, U., King, R. & Gilles, E. D. (1992). Characterisation of pellet morphology during submerged growth of Streptomyces tendae by image analysis. Biotechnol Bioeng 39, 164-170.
51. Schönholzer, O. P. F. & Zeyer, J. (1995). Quantification of fungal hyphae in leaves of deciduous trees by automated image analysis. Appl Environ Microbiol 61, 3910-3918.
52. Smith, C. M. & Calam, C. T. (1980). Variations in inocula and their influence on the productivity of antibiotic fermentations. Biotechnol Lett 2, 261-266.
53. Suelmann, R., Sievers, N. & Fischer, R. (1997). Nuclear traffic in fungal hyphae: in vivo study of nuclear migration and positioning in Aspergillus nidulans. Mol Microbiol 25, 757-769.
54. Suhr, H., Wehnert, G., Schneider, K., Bittner, C., Scholz, T., Geissler, P., Jahne, B. & Scheper, T. (1995). In situ microscopy for on line characterisation of cell populations in bioreactors, including cell concentration measurements by depth from focus. Biotechnol Bioeng 47, 106-116.
55. Thomas, C. R. (1992). Image analysis: putting filamentous micro-organisms in the picture. Trends Biotechnol 10, 343-348.
56. Thomas, C. R. & Paul, G. C. (1996). Applications of image analysis in cell technology. Curr Opin Biotechnol 7, 35-45.
57. Trinci, A. P. J. (1971). Exponential growth of the germ tubes of fungal spores. J Gen Microbiol 67, 345-348.
58. Trinci, A. P. J. (1974). A study of kinetics of hyphal extension and branch initiation of fungal mycelia. J Gen Microbiol 81, 225-236.
59. Tucker, K. G. & Thomas, C. R. (1993). Effect of biomass concentration and morphology on the rheological parameters of Penicillium chrysogenum fermentation broth. Trans IChemE (part C) 71, 111-117.
60. Tucker, K. G. & Thomas, C. R. (1994). Inoculum effect on fungal morphology: shake flasks vs agitated bioreactors. Biotechnol Tech 8, 153-156.
61. Tucker, K. G., Kelly, T., Delgrazia, P. & Thomas, C. R. (1992). Fully automatic measurement of mycelial morphology by image analysis. Biotechnol Prog 8, 353-359.
62. Turian, G. (1976). Reducing power of hyphal tips and vegetative apical dominance in fungi. Experientia 32, 989-991.
63. Vanhoutte, B., Pons, M. N., Thomas, C. R., Louvel, L. & Vivier, H. (1995). Characterisation of Penicillium chrysogenum in submerged cultures by color and monochrome image analysis. Biotechnol Bioeng 48, 1-11.
64. Van Suijdam, J. C. & Metz, B. (1981). Influence of engineering variables upon the morphology of filamentous moulds. Biotechnol Bioeng 23, 111-148.
65. Wessels, J. G. H. (1993). Wall growth, protein excretion and morphogenesis in fungi. New Phytol 123, 397-413.
66. Wiebe, M. G. & Trinci, A. P. J. (1991). Dilution rate as a determinant of mycelial morphology in continuous culture. Biotechnol Bioeng 38, 75-81.
67. Yang, H., Reichl, U., King, R. & Gilles, E. D. (1992). Measurement and simulation of the morphological development of filamentous micro-organisms. Biotechnol Bioeng 39, 44-48.
68. Yang, Y. K., Morikawa, M., Shimizu, H., Shioya, S., Suga, K., Nihira, T. & Yamada, Y. (1996). Image analysis of mycelial morphology in virginimycin production by batch culture of Streptomyces virginiae. J Ferment Bioeng 81, 7-12.