Inhibition of human and duck hepatitis B virus by 2',3'-dideoxy-3'-fluoroguanosine in vitro

Antiviral Research

Volumn 37, Issue 1, 1998, Pages 57-66

  Schröder, Ingrid ^a   Holmgren, Birgitta ^a   Öberg, Monica ^a   Löfgren, Bengt ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Antiviral treatment; Duck hepatitis B virus; Hepatitis B virus; Nucleoside analog; Quantitiative PCR

Indexed keywords

FOSCARNET; NUCLEOSIDE ANALOG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; GEL ELECTROPHORESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ASSAY;

ANIMALS; ANTIVIRAL AGENTS; CARCINOMA, HEPATOCELLULAR; CELLS, CULTURED; DIDEOXYNUCLEOSIDES; DNA-DIRECTED DNA POLYMERASE; DUCKS; ELECTROPHORESIS, AGAR GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATITIS B VIRUS; HEPATITIS B VIRUS, DUCK; HUMANS; LIVER; POLYMERASE CHAIN REACTION; TRANSFECTION; TUMOR CELLS, CULTURED; VIRUS REPLICATION;

ANAS SP.; ANIMALIA; DUCK HEPATITIS B VIRUS; HEPATITIS B VIRUS;

EID: 0031964879     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(97)00057-0     Document Type: Article

References (27)

1. Beasley, R.P., Hwang, L.-Y., Lin, C.-C., Chien, C.-S., 1981. Hepatocellular carcinoma and hepatitis B virus. Lancet 2, 1129-1133.
2. Civitico, G., Wang, Y.Y., Luscombe, C., Bishop, N., Tachedjian, G., Gust, I., Locarnini, S., 1990. Antiviral strategies in chronic hepatitis B virus infection: II. Inhibition of duck hepatitis B virus in vitro using conventional antiviral agents and supercoiled-DNA active compounds. J. Med. Virol. 31, 90-97.
3. Eron, J.J., Gorczyca, P., Kaplan, J.C., D'Aquila, R.T., 1992. Susceptibility testing by polymerase chain reaction DNA quantitation: A method to measure drug resistance of human immunodeficiency virus type 1 isolates. Proc. Natl. Acad. Sci. U.S.A. 89, 3241-3245.
4. Fourel, I., Hantz, O., Watanabe, K.A., Jacquet, C., Chomel, B., Fox, J.J., Trepo, C., 1990. Inhibitory effects of 2′-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks. Antimicrob. Agents Chemother. 34, 473-475.
5. Galle, P.R., Schlicht, H.J., Fischer, M., Schaller, H., 1988. Production of infectious duck hepatitis B virus in a human hepatoma cell line. J. Virol. 62, 1736-1740.
6. Hafkemeyer, P., Keppler-Hafkemeyer, A., Abo al Haya, M., von Janta-Lipinski, M., Matthes, E., Lehmann, C., Offensperger, W.-B., Offensperger, S., Gerok, W., Blum, H.E., 1996. Inhibition of duck hepatitis B virus replication by 2′, 3′-dideoxy-3′-fluoroguanosine in vitro and in vivo. Antimicrob. Agents Chemother. 40, 792-794.
7. Hartmann, H., Vogt, M.W., Durno, A.G., Hirsch, M.S., Hunsmann, G., Eckstein, F., 1988. Enhanced in vitro inhibition of HIV-1 replication by 3′-fluoro-3′-deoxythymidine compared to several other nucleoside analogs. AIDS Res. Hum. Retroviruses 4, 457-466.
8. Holodniy, M., Katzenstein, D.A., Sengupta, S., Wang, A.M., Casipit, C., Schwartz, D.H., Konrad, M., Groves, E., Merigan, T.C., 1991. Detection and Quantification of human immunodeficiency virus RNA in patient serum by use of polymerase chain reaction. J. Infect. Dis. 163, 862-866.
9. Kaneko, S., Miller, R.H., Feinstone, S.M., Unuora, M., Kobayashi, K., Hattori, N., Purcell, R.H., 1989. Detection of serum hepatitis B virus DNA in patients with chronic hepatitis using the polymerase chain reaction assay. Proc. Natl. Acad. Sci. U.S.A. 86, 312-316.
10. Korba, B.E., Gerin, J.L., 1992. Use of a standardized cell culture assay to assess activities of nucleoside analogs against hepatitis B virus replication. Antiviral Res. 19, 55-70.
11. Korba, B.E., Milman, G., 1991. A cell culture assay for compounds which inhibit hepatitis B virus replication. Antiviral Res. 15, 217-228.
12. Löfgren, B., Nordenfelt, E., Öberg, B., 1989. Inhibition of RNA-and DNA-dependent duck hepatitis B virus DNA polymerase activity by nucleoside and pyrophosphate analogs. Antiviral Res. 12, 301-310.
13. Löfgren, B., Vickery, K., Zhang, Y.Y., Nordenfelt, E., 1996. 2′,3′-dideoxy-3′-fluoroguanosine inhibits duck hepatitis B virus in vivo. J. Viral Hepatitis 3, 61-65.
14. Matthes, E., Reimer, K., von Janta-Lipinski, M., Meisel, H., Lehmann, C., 1991. Comparative inhibition of hepatitis B virus DNA polymerase and cellular DNA polymerases by triphosphates of sugar-modifies 5-methyldeoxycytidines and of other nucleoside analogs. Antimicrob. Agents Chemother. 35, 1254-1257.
15. Matthes, E., von Janta-Lipinski, M., Will, H., Schröder, H.C., Merz, H., Steffen, R., Müller, W.E., 1992. Inhibition of hepatitis B virus production by modified 2′, 3′-dideoxy-thymidine and 2′,3′-dideoxy-5-methylcytidine derivatives: In vitro and in vivo studies. Biochem. Pharmacol. 43, 1571-1577.
16. McMillan, J.S., Shaw, T., Angus, P.W., Locarnini, S.A., 1995. Effect of immunosuppressive and antiviral agents on hepatitis B virus replication in vitro. Hepatol. 22, 36-43.
17. Offensperger, W.-B., Offensperger, S., Walter, E., Blum, H.E., Gerok, W., 1991. Inhibition of duck hepatitis B virus infection by lysosomotropic agents. Virology 183, 415-418.
18. Pugh, J.C., Summers, J.W., 1989. Infection and uptake of duck hepatitis B virus by duck hepatocytes maintained in the presence of dimethyl sulfoxide. Virology 172, 564-572.
19. Raney, A.K., McLachlan, A., 1991. The biology of hepatitis B virus. In: McLachlan, A. (Ed.), Molecular Biology of the Hepatitis B Virus. CRC Press, Boca Raton, FL, pp. 1-37.
20. Sells, M.A., Chen, M.-L., Acs, G., 1987. Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA. Proc. Natl. Acad. Sci. U.S.A. 84, 1005-1009.
21. Shaw, T., Amor, P., Civitico, G., Boyd, M., Locarnini, S., 1994. In vitro antiviral activity of penciclovir, a novel purine nucleoside, against duck hepatitis B virus. Antimicrob. Agents Chemother. 38, 719-723.
22. Sommadossi, J.-P., 1994. Treatment of hepatitis B by nucleoside analogs: still a reality. Curr. Opin. Infect. Dis. 7, 678-682.
23. Sprengel, R., Kuhn, C., Manso, C., Will, H., 1984. Cloned duck hepatitis B virus DNA is infectious in pekin ducks. J. Virol. 52, 932-937.
24. Sprengel, R., Kuhn, C., Will, H., Schaller, H., 1985. Comparative sequence analysis of duck and human hepatitis B virus genomes. J. Med. Virol. 15, 323-333.
25. Staschke, K.A., Colacino, J.M., Mabry, T.E., Jones, C.D., 1994. The in vitro anti-hepatitis B virus activity of FIAU [1-(2′-deoxy-2′-fluoro-1-β-D-arabinofuranosyl-5-iodo)uracil] is selective, reversible, and determined, at least in part, by the host cell. Antiviral Res. 23, 45-61.
26. Tuttleman, J.S., Pugh, J.C., Summers, J.W., 1986. In vitro experimental infection of primary duck hepatocyte cultures with duck hepatitis B virus. J. Virol. 58, 17-25.
27. Wong, D.K.H., Cheung, A.M., O'Rourke, K., Naylor, C.D., Detsky, A.S., Heathcote, J., 1993. Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann. Intern. Med. 119, 312-323.