2′,3′-Dideoxy-3′-fluoroguanosine inhibits duck hepatitis B virus in vivo

Journal of Viral Hepatitis

Volumn 3, Issue 2, 1996, Pages 61-65

  Lofgren B ^a   Vickery, K ^b   Zhang, Y Y ^a   Nordenfelt, E ^c  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF SYDNEY   (Australia)

^c SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

Author keywords

Anti viral treatment; Duck hepatitis B virus; Hepatitis B virus; Nucleoside analogues

Indexed keywords

2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; ANTIVIRUS AGENT; FLUORINE; VIRUS DNA;

ANIMAL; ANIMAL DISEASE; ARTICLE; BIOSYNTHESIS; BIRD DISEASE; DUCK; GENETICS; HEPATITIS B; HEPATITIS B VIRUS; ISOLATION AND PURIFICATION;

ANIMALS; ANTIVIRAL AGENTS; BIRD DISEASES; DIDEOXYNUCLEOSIDES; DNA, VIRAL; DUCKS; FLUORINE; HEPATITIS B; HEPATITIS B VIRUS;

EID: 0030094065     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2893.1996.tb00082.x     Document Type: Article

References (20)

1. Wong DKH, Cheung AM, O'Rourke K, Naylor CD, Detsky AS, Heathcote J. Effect of α-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A meta-analysis. Ann Intern Med 1993; 119: 312-323.
2. Hayashi Y, Koike K. Interferon inhibits hepatitis B virus replication in a stable expression system of transfected viral DNA. J Virol 1989; 63: 2936-2940.
3. Davis MG, Jansen RW. Inhibition of hepatitis B virus in tissue culture by alpha interferon. Antimicrob Agents Chemother 1994; 38: 2921-2924.
4. Jacyna MR, Thomas HC. Antiviral therapy: hepatitis B. Brit Med Bull 1990; 46: 368-382.
5. Sommadossi J-P. Treatment of hepatitis B by nucleoside analogs: still a reality. Curr Opin Infect Dis 1994; 7: 678-682.
6. Sherker AH, Hirota K, Omata M, Okuda K. Effects of foscarnet on serum and liver viral DNA in chronic duck hepatitis B virus infection. In: Zuckerman AJ, ed. Viral Hepatitis and Liver Disease. New York: Alan R Liss, Inc., 1988: 532-534.
7. Lee B, Luo WX, Suzuki S, Robins MJ, Tyrell DL. In vitro and in vivo comparison of the abilities of purine and pyrimidine 2′,3′-dideoxynucleosides to inhibit duck hepadnavirus. Antimicrob Agents Chemother 1989; 33: 336-339.
8. Bazin H, Chattopadhyaya J, Datema R et al. An analysis of the inhibition of replication of HIV and MULV by some 3′-blocked pyrimidine analogues. Biochem Pharmacol 1989; 38: 109-119.
9. Löfgren B, Habteyesus A, Nordenfelt E, Eriksson S, Öberg B. Inefficient phosphorylation of 3′-fluoro-2′,3′-dideoxythymidine in liver cells may explain its lack of inhibition of duck hepatitis B virus replication in vivo. Antiviral Res 1990; 12: 301-310.
10. Wang Y, Bowden S, Shaw T et al. Inhibition of duck hepatitis B virus replication in vivo by the nucleoside analogue ganciclovir (9-(2-hydroxy-1-(hydroxymethyl)-ethoxymethyl)guanine). Antivir Chem Chemother 1991; 2: 107-114.
11. Löfgren B. Antiviral Compounds Against Hepadnaviruses. Experimental Studies. PhD thesis. Lund University, Lund, Sweden, 1993.
12. Tsiquaye KN, Slomka MJ, Maung M. Oral famciclovir against duck hepatitis B virus replication in hepatic and nonhepatic tissues of ducklings infected in ovo. J Med Virol 1994; 42: 306-310.
13. Sullivan V, Talarico CL, Stanat SC, Davis M, Coen DM, Biron KK. A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells. Nature 1992; 358: 162-164.
14. Heijtink RA, De Wilde GA, Kruining J et al. Inhibitory effect of 9-(2-phosphonylmethoxy-ethyl)adenine (PMEA) on human and duck hepatitis B virus infection. Antiviral Res 1993; 21: 141-153.
15. Locarnini SA, Guo K, Lucas CR, Gust ID. Inhibition of HBV DNA replication by ganciclovir in patients with AIDS. Lancet 1989; ii: 1225-1226.
16. Niu J, Wang Y, Dixon R et al. The use of ampligen alone and in combination with ganciclovir and coumermycin A1 for the treatment of ducks congenitally-infected with duck hepatitis B virus. Antiviral Res 1993; 21: 155-171.
17. Wang Y, Luscombe C, Bowden S, Shaw T, Locarnini S. Inhibition of duck hepatitis B virus DNA replication by antiviral chemotherapy with ganciclovir-nalidixic acid. Antimicrob Agents Chemother 1995; 39: 556-558.
18. Offensperger WB, Offensperger S, Walter E, Teubner K. In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides. EMBO J 1993; 12: 1257-1262.
19. Tyrell DLJ, Mitchell MC, De Man RA et al. Phase II trial of Lamivudine for chronic hepatitis B. (Abstract). Hepatology 1994; 18: 112A.
20. Thomas HC. Treatment of hepatitis B viral infection. In: Zuckerman AJ, ed. Viral Hepatitis and Liver Disease. New York: Alan R Liss. Inc., 1988: 817-822.