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Volumn 24, Issue 2, 1998, Pages 332-340

Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury

Author keywords

Oxidative damage; Spin label; Superoxide; Transition metals; Traumatic brain injury

Indexed keywords

ANTIOXIDANT; DEFEROXAMINE; HYDROXYLAMINE; NITROXIDE; REACTIVE OXYGEN METABOLITE;

EID: 0031963829     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00267-0     Document Type: Article
Times cited : (57)

References (43)
  • 2
    • 0026540898 scopus 로고
    • Pharmacological strategies in CNS trauma
    • -35
    • Faden A. I., Salzman S. Pharmacological strategies in CNS trauma. Trends Pharmacol. Sci. 13:1992;29-35.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 29
    • Faden, A.I.1    Salzman, S.2
  • 3
    • 0022133358 scopus 로고
    • Brown memorial lecture. Oxygen radicals in cerebral vascular injury
    • -516
    • Kontos H. A., George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury. Circ. Res. 57:1985;508-516.
    • (1985) Circ. Res. , vol.57 , pp. 508
    • Kontos, H.A.1    George, E.2
  • 4
    • 0025285843 scopus 로고
    • The molecular basis of brain injury and brain edema: The role of oxygen free radicals
    • -11
    • Ikeda Y., Long D. M. The molecular basis of brain injury and brain edema: The role of oxygen free radicals. Neurosurgery. 27:1990;1-11.
    • (1990) Neurosurgery , vol.27 , pp. 1
    • Ikeda, Y.1    Long, D.M.2
  • 5
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • -1623
    • Halliwell B. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1992;1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609
    • Halliwell, B.1
  • 6
    • 0028803753 scopus 로고
    • U83836E reduces secondary brain injury in a rabbit model of cryogenic trauma
    • -477
    • Wilson J. T., Gross C. E., Bednar M. M., Shackford S. R. U83836E reduces secondary brain injury in a rabbit model of cryogenic trauma. J. Trauma. 39:1995;473-477.
    • (1995) J. Trauma , vol.39 , pp. 473
    • Wilson, J.T.1    Gross, C.E.2    Bednar, M.M.3    Shackford, S.R.4
  • 7
    • 0029130550 scopus 로고
    • Glutamate release and free radical production following brain injury: Effects of posttraumatic hypothermia
    • -1711
    • Globus M. Y., Alonso O., Dietrich W. D., Busto R., Ginsberg M. D. Glutamate release and free radical production following brain injury: Effects of posttraumatic hypothermia. J. Neurochem. 65:1995;1704-1711.
    • (1995) J. Neurochem. , vol.65 , pp. 1704
    • Globus, M.Y.1    Alonso, O.2    Dietrich, W.D.3    Busto, R.4    Ginsberg, M.D.5
  • 8
    • 0029848165 scopus 로고    scopus 로고
    • Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice
    • -891
    • Mikawa S., Kinouchi H., Kamii H., Gobbel G. T., Chen S. F., Carlson E., Epstein C. J., Chan P. H. Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice. J. Neurosurg. 85:1996;885-891.
    • (1996) J. Neurosurg. , vol.85 , pp. 885
    • Mikawa, S.1    Kinouchi, H.2    Kamii, H.3    Gobbel, G.T.4    Chen, S.F.5    Carlson, E.6    Epstein, C.J.7    Chan, P.H.8
  • 9
    • 0024474034 scopus 로고
    • Brain phospholipase A2 is activated after experimental closed head injury in the rat
    • -1546
    • Shohami E., Shapira Y., Yadid G., Reisfeld N., Yedgar S. Brain phospholipase A2 is activated after experimental closed head injury in the rat. J. Neurochem. 53:1989;1541-1546.
    • (1989) J. Neurochem. , vol.53 , pp. 1541
    • Shohami, E.1    Shapira, Y.2    Yadid, G.3    Reisfeld, N.4    Yedgar, S.5
  • 10
    • 0024410982 scopus 로고
    • Comparative study of different iron-chelating agents in cold-induced brain edema
    • -824
    • Ikeda Y., Ikeda K., Long D. M. Comparative study of different iron-chelating agents in cold-induced brain edema. Neurosurgery. 24:1989;820-824.
    • (1989) Neurosurgery , vol.24 , pp. 820
    • Ikeda, Y.1    Ikeda, K.2    Long, D.M.3
  • 11
    • 0027164318 scopus 로고
    • Brain injury and repair mechanisms: The potential for pharmacologic therapy in closed-head trauma
    • -979
    • White B. C., Krause G. S. Brain injury and repair mechanisms: The potential for pharmacologic therapy in closed-head trauma. Ann. Emerg. Med. 22:1993;970-979.
    • (1993) Ann. Emerg. Med. , vol.22 , pp. 970
    • White, B.C.1    Krause, G.S.2
  • 13
    • 0028218770 scopus 로고
    • Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy
    • -33
    • Mattson M. P., Scheff S. W. Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy. J. Neurotrauma. 11:1994;3-33.
    • (1994) J. Neurotrauma , vol.11 , pp. 3
    • Mattson, M.P.1    Scheff, S.W.2
  • 14
    • 0028800428 scopus 로고
    • Protective effects of lazaroid U74389F (16-desmethyl tirilazad) on endrin-induced lipid peroxidation and DNA damage in brain and liver and regional distribution of catalase activity in rat brain
    • -872
    • Bagchi M., Ghosh S., Bagchi D., Hassoun E., Stohs S. J. Protective effects of lazaroid U74389F (16-desmethyl tirilazad) on endrin-induced lipid peroxidation and DNA damage in brain and liver and regional distribution of catalase activity in rat brain. Free Radic. Biol. Med. 19:1995;867-872.
    • (1995) Free Radic. Biol. Med. , vol.19 , pp. 867
    • Bagchi, M.1    Ghosh, S.2    Bagchi, D.3    Hassoun, E.4    Stohs, S.J.5
  • 15
    • 0030027456 scopus 로고    scopus 로고
    • Mild pre- And posttraumatic hypothermia attenuates blood-brain barrier damage following controlled cortical impact injury in the rat
    • -9
    • Smith S. L., Hall E. D. Mild pre- and posttraumatic hypothermia attenuates blood-brain barrier damage following controlled cortical impact injury in the rat. J. Neurotrauma. 13:1996;1-9.
    • (1996) J. Neurotrauma , vol.13 , pp. 1
    • Smith, S.L.1    Hall, E.D.2
  • 16
    • 0028298805 scopus 로고
    • Alpha-Phenyl-tert-butyl-nitrone inhibits free radical release in brain concussion
    • -691
    • Sen S., Goldman H., Morehead M., Murphy S., Phillis J. W. alpha-Phenyl-tert-butyl-nitrone inhibits free radical release in brain concussion. Free Radic. Biol. Med. 16:1994;685-691.
    • (1994) Free Radic. Biol. Med. , vol.16 , pp. 685
    • Sen, S.1    Goldman, H.2    Morehead, M.3    Murphy, S.4    Phillis, J.W.5
  • 17
    • 0028822051 scopus 로고
    • Prevention of ischemia/reperfusion-induced alterations in synaptosomal membrane-associated proteins and lipids by N-tert-butyl-alpha-phenylnitrone and difluoromethylornithine
    • -600
    • Hall N. C., Carney J. M., Cheng M., Butterfield D. A. Prevention of ischemia/reperfusion-induced alterations in synaptosomal membrane-associated proteins and lipids by N-tert-butyl-alpha-phenylnitrone and difluoromethylornithine. Neuroscience. 69:1995;591-600.
    • (1995) Neuroscience , vol.69 , pp. 591
    • Hall, N.C.1    Carney, J.M.2    Cheng, M.3    Butterfield, D.A.4
  • 18
    • 0031029393 scopus 로고    scopus 로고
    • Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone
    • -678
    • Butterfield D. A., Howard B. J., Yatin S., Allen K. L., Carney J. M. Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone. Proc. Natl. Acad. Sci. USA. 94:1997;674-678.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 674
    • Butterfield, D.A.1    Howard, B.J.2    Yatin, S.3    Allen, K.L.4    Carney, J.M.5
  • 19
    • 0022628380 scopus 로고
    • Superoxide production in experimental brain injury
    • -807
    • Kontos H. A., Wei E. P. Superoxide production in experimental brain injury. J. Neurosurg. 64:1986;803-807.
    • (1986) J. Neurosurg. , vol.64 , pp. 803
    • Kontos, H.A.1    Wei, E.P.2
  • 20
    • 0023255806 scopus 로고
    • Protective effects of liposome-entrapped superoxide dismutase on posttraumatic brain edema
    • -547
    • Chan P. H., Longar S., Fishman R. A. Protective effects of liposome-entrapped superoxide dismutase on posttraumatic brain edema. Ann. Neurol. 21:1987;540-547.
    • (1987) Ann. Neurol. , vol.21 , pp. 540
    • Chan, P.H.1    Longar, S.2    Fishman, R.A.3
  • 21
    • 0024505857 scopus 로고
    • Oxygen free radicals in the genesis of traumatic and peritumoral brain edema
    • -685
    • Ikeda Y., Anderson J. H., Long D. M. Oxygen free radicals in the genesis of traumatic and peritumoral brain edema. Neurosurgery. 24:1989;679-685.
    • (1989) Neurosurgery , vol.24 , pp. 679
    • Ikeda, Y.1    Anderson, J.H.2    Long, D.M.3
  • 24
    • 0028111408 scopus 로고
    • A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats
    • -1188
    • Rachmilewitz D., Karmeli F., Okon E., Samuni A. A novel antiulcerogenic stable radical prevents gastric mucosal lesions in rats. Gut. 35:1994;1181-1188.
    • (1994) Gut , vol.35 , pp. 1181
    • Rachmilewitz, D.1    Karmeli, F.2    Okon, E.3    Samuni, A.4
  • 25
    • 0029933628 scopus 로고    scopus 로고
    • Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat
    • -28
    • Beit-Yannai E., Zhang R., Trembovler V., Samuni A., Shohami E. Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat. Brain Res. 717:1996;22-28.
    • (1996) Brain Res. , vol.717 , pp. 22
    • Beit-Yannai, E.1    Zhang, R.2    Trembovler, V.3    Samuni, A.4    Shohami, E.5
  • 26
    • 0029826118 scopus 로고    scopus 로고
    • Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated proteins by N-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (Tempol)
    • -2050
    • Howard B. J., Yatin S., Hensley K., Allen K. L., Kelly J. P., Carney J., Butterfield D. A. Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated proteins by N-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (Tempol). J. Neurochem. 67:1996;2045-2050.
    • (1996) J. Neurochem. , vol.67 , pp. 2045
    • Howard, B.J.1    Yatin, S.2    Hensley, K.3    Allen, K.L.4    Kelly, J.P.5    Carney, J.6    Butterfield, D.A.7
  • 28
    • 0029957646 scopus 로고    scopus 로고
    • Stimulation by nitroxides of catalase-like activity of hemeproteins. Kinetics and mechanism
    • -26025
    • Krishna M. C., Samuni A., Taira J., Goldstein S., Mitchell J. B., Russo A. Stimulation by nitroxides of catalase-like activity of hemeproteins. Kinetics and mechanism. J. Biol. Chem. 271:1996;26018-26025.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26018
    • Krishna, M.C.1    Samuni, A.2    Taira, J.3    Goldstein, S.4    Mitchell, J.B.5    Russo, A.6
  • 29
    • 0023930960 scopus 로고
    • Experimental closed head injury in rats: Mechanical, pathophysiologic, and neurologic properties
    • -265
    • Shapira Y., Shohami E., Sidi A., Soffer D., Freeman S., Cotev S. Experimental closed head injury in rats: Mechanical, pathophysiologic, and neurologic properties. Crit. Care Med. 16:1988;258-265.
    • (1988) Crit. Care Med. , vol.16 , pp. 258
    • Shapira, Y.1    Shohami, E.2    Sidi, A.3    Soffer, D.4    Freeman, S.5    Cotev, S.6
  • 30
    • 0014046826 scopus 로고
    • Neuropathological aspects of brain edema
    • -14
    • Klatzo I. Neuropathological aspects of brain edema. J. Neuropathol. Exp. Neurol. 26:1967;1-14.
    • (1967) J. Neuropathol. Exp. Neurol. , vol.26 , pp. 1
    • Klatzo, I.1
  • 31
    • 0023856405 scopus 로고
    • Quantitative evaluation of vascular permeability in the gerbil brain after transient ischemia using Evans blue fluorescence
    • -284
    • Uyama O., Okamura N., Yanase M., Narita M., Kawabata K., Sugita M. Quantitative evaluation of vascular permeability in the gerbil brain after transient ischemia using Evans blue fluorescence. J. Cereb. Blood Flow Metab. 8:1988;282-284.
    • (1988) J. Cereb. Blood Flow Metab. , vol.8 , pp. 282
    • Uyama, O.1    Okamura, N.2    Yanase, M.3    Narita, M.4    Kawabata, K.5    Sugita, M.6
  • 32
    • 0027213179 scopus 로고
    • Blood-brain barrier permeability, cerebral edema, and neurologic function after closed head injury in rats
    • -148
    • Shapira Y., Setton D., Artru A. A., Shohami E. Blood-brain barrier permeability, cerebral edema, and neurologic function after closed head injury in rats. Anesth. Analg. 77:1993;141-148.
    • (1993) Anesth. Analg. , vol.77 , pp. 141
    • Shapira, Y.1    Setton, D.2    Artru, A.A.3    Shohami, E.4
  • 33
    • 0028920429 scopus 로고
    • Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat
    • -62
    • Shohami E., Novikov M., Bass R. Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat. Brain Res. 674:1995;55-62.
    • (1995) Brain Res. , vol.674 , pp. 55
    • Shohami, E.1    Novikov, M.2    Bass, R.3
  • 35
    • 84996120592 scopus 로고
    • Oxidants and the central nervous system: Some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke?
    • -33
    • Halliwell B. Oxidants and the central nervous system: Some fundamental questions. Is oxidant damage relevant to Parkinson's disease, Alzheimer's disease, traumatic injury or stroke? Acta Neurol. Scand. Suppl. 126:1989;23-33.
    • (1989) Acta Neurol. Scand. Suppl. , vol.126 , pp. 23
    • Halliwell, B.1
  • 36
    • 0026026674 scopus 로고
    • Iron-induced lipid peroxidation and brain injury responses
    • -180
    • Willmore L. J., Triggs W. J. Iron-induced lipid peroxidation and brain injury responses. Int. J. Dev. Neurosci. 9:1991;175-180.
    • (1991) Int. J. Dev. Neurosci. , vol.9 , pp. 175
    • Willmore, L.J.1    Triggs, W.J.2
  • 37
  • 38
    • 0025163204 scopus 로고
    • Principles of the metabolism of nitroxides and their implications for spin trapping
    • -405
    • Swartz H. M. Principles of the metabolism of nitroxides and their implications for spin trapping. Free Radic. Res. Commun. 9:1990;399-405.
    • (1990) Free Radic. Res. Commun. , vol.9 , pp. 399
    • Swartz, H.M.1
  • 40
    • 0026522028 scopus 로고
    • Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurons
    • -197
    • Yue T. L., Gu J. L., Lysko P. G., Cheng H. Y., Barone F. C., Feuerstein G. Neuroprotective effects of phenyl-t-butyl-nitrone in gerbil global brain ischemia and in cultured rat cerebellar neurons. Brain Res. 574:1992;193-197.
    • (1992) Brain Res. , vol.574 , pp. 193
    • Yue, T.L.1    Gu, J.L.2    Lysko, P.G.3    Cheng, H.Y.4    Barone, F.C.5    Feuerstein, G.6
  • 41
    • 0029067088 scopus 로고
    • N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia
    • -5061
    • Folbergrova J., Zhao Q., Katsura K., Siesjo B. K. N-tert-butyl-alpha-phenylnitrone improves recovery of brain energy state in rats following transient focal ischemia. Proc. Natl. Acad. Sci. USA. 92:1995;5057-5061.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5057
    • Folbergrova, J.1    Zhao, Q.2    Katsura, K.3    Siesjo, B.K.4
  • 43
    • 0030934316 scopus 로고    scopus 로고
    • Stable nitroxide radicals protect lipid acyl chains from radiation damage
    • -1174
    • Samuni A. M., Barenholz Y. Stable nitroxide radicals protect lipid acyl chains from radiation damage. Free Radic. Biol. Med. 22:1997;1165-1174.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 1165
    • Samuni, A.M.1    Barenholz, Y.2


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