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Volumn 49, Issue 1, 1998, Pages 24-30

Improved L-lysine yield with Corynebacterium glutamicum: Use of dapA resulting in increased flux combined with growth limitation

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE; SYNTHETASE;

EID: 0031963010     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530051132     Document Type: Article
Times cited : (68)

References (36)
  • 1
    • 0030201057 scopus 로고    scopus 로고
    • Improving production of aromatic compounds in Escherichia coli by metabolic engineering
    • Berry A (1996) Improving production of aromatic compounds in Escherichia coli by metabolic engineering. Trends Biotechnol 14: 250-256
    • (1996) Trends Biotechnol , vol.14 , pp. 250-256
    • Berry, A.1
  • 2
    • 0002314438 scopus 로고
    • Homoserine dehydrogenase
    • Black S, Wright NG (1955) Homoserine dehydrogenase. J Biol Chem 213: 51-60
    • (1955) J Biol Chem , vol.213 , pp. 51-60
    • Black, S.1    Wright, N.G.2
  • 3
    • 0027465765 scopus 로고
    • Strains of Corynebacterium glutamicum with different lysine productivities may have different lysine excretion systems
    • Bröer S, Eggeling L, Krämer R (1993) Strains of Corynebacterium glutamicum with different lysine productivities may have different lysine excretion systems. Appl Environ Microbiol 59: 16-321
    • (1993) Appl Environ Microbiol , vol.59 , pp. 16-321
    • Bröer, S.1    Eggeling, L.2    Krämer, R.3
  • 4
    • 0024145176 scopus 로고
    • Regulation of enzymes of lysine biosynthesis in Corynebacterium glutamicum
    • Cremer J, Treptow C, Eggeling L, Sahm H (1988) Regulation of enzymes of lysine biosynthesis in Corynebacterium glutamicum. J Gen Microbiol 134: 3221-3229
    • (1988) J Gen Microbiol , vol.134 , pp. 3221-3229
    • Cremer, J.1    Treptow, C.2    Eggeling, L.3    Sahm, H.4
  • 5
    • 0025052104 scopus 로고
    • Cloning the dapA dapB cluster of the lysine-secreting bacterium Corynebacterium glutamicum
    • Cremer J, Eggeling L, Sahm H (1990) Cloning the dapA dapB cluster of the lysine-secreting bacterium Corynebacterium glutamicum. Mol Gen Genet 220: 478-480
    • (1990) Mol Gen Genet , vol.220 , pp. 478-480
    • Cremer, J.1    Eggeling, L.2    Sahm, H.3
  • 6
    • 0025755467 scopus 로고
    • Control of the lysine biosynthetic sequence in Corynebacterium glutamicum as analyzed by overexpression of the individual corresponding genes
    • Cremer J, Eggeling L, Sahm H (1991) Control of the lysine biosynthetic sequence in Corynebacterium glutamicum as analyzed by overexpression of the individual corresponding genes. Appl Environ Microbiol 57: 1746-1752
    • (1991) Appl Environ Microbiol , vol.57 , pp. 1746-1752
    • Cremer, J.1    Eggeling, L.2    Sahm, H.3
  • 7
    • 0027772102 scopus 로고
    • Identification and removal of impediments to biocatalytic synthesis of aromatics from D-glucose: Rate-limiting enzymes in the common pathway of aromatic amino acid biosynthesis
    • Dell KA, Frost JW (1993) Identification and removal of impediments to biocatalytic synthesis of aromatics from D-glucose: rate-limiting enzymes in the common pathway of aromatic amino acid biosynthesis. J Am Chem Soc 115: 11581-11589
    • (1993) J Am Chem Soc , vol.115 , pp. 11581-11589
    • Dell, K.A.1    Frost, J.W.2
  • 8
    • 0028340817 scopus 로고
    • Biology of L-lysine overproduction by Corynebacterium glutamicum
    • Eggeling L (1994) Biology of L-lysine overproduction by Corynebacterium glutamicum. Amino Acids 6: 261-272
    • (1994) Amino Acids , vol.6 , pp. 261-272
    • Eggeling, L.1
  • 9
    • 0002188159 scopus 로고    scopus 로고
    • Quantifying and directing metabolite flux: Application to amino acid overproduction
    • Eggeling L, De Graaf AA, Sahm H (1996) Quantifying and directing metabolite flux: application to amino acid overproduction. Adv Biochem Eng 54: 2-30
    • (1996) Adv Biochem Eng , vol.54 , pp. 2-30
    • Eggeling, L.1    De Graaf, A.A.2    Sahm, H.3
  • 10
    • 0023705150 scopus 로고
    • Organization and regulation of the Corynebacterium glutamicum hom-thrB and thrC loci
    • Follettie MT, Shin HK, Sinskey AJ (1988) Organization and regulation of the Corynebacterium glutamicum hom-thrB and thrC loci. Mol Microbiol 2: 53-62
    • (1988) Mol Microbiol , vol.2 , pp. 53-62
    • Follettie, M.T.1    Shin, H.K.2    Sinskey, A.J.3
  • 11
    • 14744300708 scopus 로고
    • Bulk amino-acid fermentation: Technology and commodity trading
    • Hodgson J (1994) Bulk amino-acid fermentation: technology and commodity trading. Biotechnology 12: 152-155
    • (1994) Biotechnology , vol.12 , pp. 152-155
    • Hodgson, J.1
  • 12
    • 0019869334 scopus 로고
    • The molecular basis of dominance
    • Kacser H, Burns JA (1981) The molecular basis of dominance. Genetics 97: 639-666
    • (1981) Genetics , vol.97 , pp. 639-666
    • Kacser, H.1    Burns, J.A.2
  • 13
  • 14
    • 0027164654 scopus 로고
    • Isoleucine synthesis in Corynebacterium glutamicum: Molecular analysis of the ilvB-ilvN-ilvC operon
    • Keilhauer C, Eggeling L, Sahm H (1993) Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operon. J Bacteriol 175: 5595-5603
    • (1993) J Bacteriol , vol.175 , pp. 5595-5603
    • Keilhauer, C.1    Eggeling, L.2    Sahm, H.3
  • 15
    • 0026257214 scopus 로고
    • Metabolic activity control of the L-lysine fermentation by restrained growth fed-batch strategies
    • Kiss RD. Stephanopoulos G (1991) Metabolic activity control of the L-lysine fermentation by restrained growth fed-batch strategies. Biotechnol Prog 7: 501-509
    • (1991) Biotechnol Prog , vol.7 , pp. 501-509
    • Kiss, R.D.1    Stephanopoulos, G.2
  • 16
    • 0001443366 scopus 로고
    • Means of terminating reactions
    • Klingenberg M, Pfaff E (1977) Means of terminating reactions. Methods Enzymol 10: 680-684
    • (1977) Methods Enzymol , vol.10 , pp. 680-684
    • Klingenberg, M.1    Pfaff, E.2
  • 17
    • 0025860534 scopus 로고
    • Physiologically motivated strategies for control of the fed-batch cultivation of recombinant Escherichia coli for phenylalanine production
    • Konstantinov KB, Nishio N, Seki T, Yoshida T (1991) Physiologically motivated strategies for control of the fed-batch cultivation of recombinant Escherichia coli for phenylalanine production. J Ferment Bioeng 71: 350-355
    • (1991) J Ferment Bioeng , vol.71 , pp. 350-355
    • Konstantinov, K.B.1    Nishio, N.2    Seki, T.3    Yoshida, T.4
  • 18
    • 0028944577 scopus 로고
    • Structure of the gluABCD cluster encoding the glutamate uptake system of Corynebacterium glutamicum
    • Kronemeyer W, Peekhaus N, Krämer R, Sahm H, Eggeling L (1995) Structure of the gluABCD cluster encoding the glutamate uptake system of Corynebacterium glutamicum. J Bacteriol 177: 1152-1158
    • (1995) J Bacteriol , vol.177 , pp. 1152-1158
    • Kronemeyer, W.1    Peekhaus, N.2    Krämer, R.3    Sahm, H.4    Eggeling, L.5
  • 19
    • 0001595180 scopus 로고    scopus 로고
    • Amino acids technical production and use. Products of primary metabolism
    • Leuchtenberger W (1996) Amino acids technical production and use. Products of primary metabolism. Biotechnology 6: 455-502.
    • (1996) Biotechnology , vol.6 , pp. 455-502
    • Leuchtenberger, W.1
  • 20
    • 0030050268 scopus 로고    scopus 로고
    • Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing
    • Marx A, Graaf AA de, Wiechert W, Eggeling L, Sahm H (1996) Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing. Biotechnol Bioeng 49: 111-129
    • (1996) Biotechnol Bioeng , vol.49 , pp. 111-129
    • Marx, A.1    De Graaf, A.A.2    Wiechert, W.3    Eggeling, L.4    Sahm, H.5
  • 21
    • 0343886785 scopus 로고
    • Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. Repression of the enzymes in threonine biosynthesis
    • Miyajima R, Shiio (1971) Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. Repression of the enzymes in threonine biosynthesis. Agr Biol Chem 35: 424-430
    • (1971) Agr Biol Chem , vol.35 , pp. 424-430
    • Miyajima, R.1    Shiio2
  • 22
    • 0014247152 scopus 로고
    • Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. Inhibition by amino acids of the enzymes in threonine biosynthesis
    • Tokyo
    • Miyajima R, Otsuka, Shiio I (1968) Regulation of aspartate family amino acid biosynthesis in Brevibacterium flavum. Inhibition by amino acids of the enzymes in threonine biosynthesis. J Biochem (Tokyo) 63: 139-148
    • (1968) J Biochem , vol.63 , pp. 139-148
    • Miyajima, R.1    Otsuka2    Shiio, I.3
  • 23
    • 0028791418 scopus 로고
    • Use of feedback-resistant threonine dehydratases of Corynebacterium glutamicum to increase carbon flux towards L-isoleucine
    • Morbach S, Sahm H, Eggeling L (1995) Use of feedback-resistant threonine dehydratases of Corynebacterium glutamicum to increase carbon flux towards L-isoleucine. Appl Environ Microbiol 61: 4315-4320
    • (1995) Appl Environ Microbiol , vol.61 , pp. 4315-4320
    • Morbach, S.1    Sahm, H.2    Eggeling, L.3
  • 24
    • 0029884122 scopus 로고    scopus 로고
    • Engineering the homoserine dehydrogenase and threonine dehydratase control points to analyse flux towards L-isoleucine in Corynebacterium glutamicum
    • Morbach S, Kelle R, Winkels S, Sahm H, Eggeling L (1996a) Engineering the homoserine dehydrogenase and threonine dehydratase control points to analyse flux towards L-isoleucine in Corynebacterium glutamicum. Appl Microbiol Biotechnol 45: 612-620
    • (1996) Appl Microbiol Biotechnol , vol.45 , pp. 612-620
    • Morbach, S.1    Kelle, R.2    Winkels, S.3    Sahm, H.4    Eggeling, L.5
  • 25
    • 0029860181 scopus 로고    scopus 로고
    • L-isoleucine production with Corynebacterium glutamicum: Further flux increase and limitation of export
    • Morbach S, Sahm H, Eggeling L (1996b) L-isoleucine production with Corynebacterium glutamicum: further flux increase and limitation of export. Appl Environ Microbiol 62: 4345-4351
    • (1996) Appl Environ Microbiol , vol.62 , pp. 4345-4351
    • Morbach, S.1    Sahm, H.2    Eggeling, L.3
  • 26
    • 0028121787 scopus 로고
    • Stable expression of hom-I-thrB in Corynebacterium glutamicum and its effect on the carbon flux to threonine and related amino acids
    • Reinscheid DJ, Kronemeyer W, Eggeling L, Eikmanns BJ, Sahm H (1994) Stable expression of hom-I-thrB in Corynebacterium glutamicum and its effect on the carbon flux to threonine and related amino acids. Appl Environ Microbiol 60: 126-132
    • (1994) Appl Environ Microbiol , vol.60 , pp. 126-132
    • Reinscheid, D.J.1    Kronemeyer, W.2    Eggeling, L.3    Eikmanns, B.J.4    Sahm, H.5
  • 27
    • 0022538731 scopus 로고
    • Chromosomal location and nucleotide sequence of the Escherichia coli dapA gene
    • Richaud F, Richaud C, Rate, P, Patte J-C (1986) Chromosomal location and nucleotide sequence of the Escherichia coli dapA gene. J Bacteriol 166: 297-300
    • (1986) J Bacteriol , vol.166 , pp. 297-300
    • Richaud, F.1    Richaud, C.2    Rate, P.3    Patte, J.-C.4
  • 28
    • 0018337795 scopus 로고
    • The measurement of membrane potential and pH in cells, organelles and vesicle
    • Rottenberg H (1979) The measurement of membrane potential and pH in cells, organelles and vesicle. Methods Enzymol 7: 547-569
    • (1979) Methods Enzymol , vol.7 , pp. 547-569
    • Rottenberg, H.1
  • 30
    • 0025239615 scopus 로고
    • High-frequency conjugal plasmid transfer from gram-negative Escherichia coli to various gram-positive coryneform bacteria
    • Schäfer A, Kalinowski J, Simon R, Seep-Feldhaus A, Pühler A (1990) High-frequency conjugal plasmid transfer from gram-negative Escherichia coli to various gram-positive coryneform bacteria. J Bacteriol 172: 1663-1666
    • (1990) J Bacteriol , vol.172 , pp. 1663-1666
    • Schäfer, A.1    Kalinowski, J.2    Simon, R.3    Seep-Feldhaus, A.4    Pühler, A.5
  • 32
    • 0026761151 scopus 로고
    • Isolation and prominent characteristics of an L-lysine-hyperproducing strain of Corynebacterium glutamicum
    • Schrumpf B, Eggeling L, Sahm H (1992) Isolation and prominent characteristics of an L-lysine-hyperproducing strain of Corynebacterium glutamicum. Appl Microbiol Biotechnol 37: 566-571
    • (1992) Appl Microbiol Biotechnol , vol.37 , pp. 566-571
    • Schrumpf, B.1    Eggeling, L.2    Sahm, H.3
  • 34
    • 0027572102 scopus 로고
    • Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction
    • Vallino JJ, Stephanopoulos G (1993) Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction. Biotechnol Bioeng 41: 633-646
    • (1993) Biotechnol Bioeng , vol.41 , pp. 633-646
    • Vallino, J.J.1    Stephanopoulos, G.2
  • 35
    • 0028981722 scopus 로고
    • Disbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion defective mutants
    • Vrljic M, Kronemeyer W, Sahm H, Eggeling L (1995) Disbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion defective mutants. J Bacteriol 177: 4021-4027
    • (1995) J Bacteriol , vol.177 , pp. 4021-4027
    • Vrljic, M.1    Kronemeyer, W.2    Sahm, H.3    Eggeling, L.4
  • 36
    • 0029818343 scopus 로고    scopus 로고
    • A new type of transporter with a new type of cellular function: L-lysine export in Corynebacterium glutamicum
    • Vrljic M, Sahm H, Eggeling L (1996) A new type of transporter with a new type of cellular function: L-lysine export in Corynebacterium glutamicum. Mol Microbiol 22: 815-826
    • (1996) Mol Microbiol , vol.22 , pp. 815-826
    • Vrljic, M.1    Sahm, H.2    Eggeling, L.3


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