Rejection of wild-type and genetically engineered major histocompatibility complex-deficient glial cell xenografts in the central nervous system results in bystander demyelination and wallerian degeneration

Neuroscience

Volumn 85, Issue 1, 1998, Pages 269-280

  O'Leary, M T ^a   Bujdoso, R ^a   Blakemore, W F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Axon degeneration; Bystander damage; CNS; Glia; MHC knockout; Multiple sclerosis

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; DEMYELINATION; FEMALE; GLIA CELL; GRAFT REJECTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MULTIPLE SCLEROSIS; NERVE FIBER DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; AXONS; DEMYELINATING DISEASES; FEMALE; GENETIC ENGINEERING; GLIAL FIBRILLARY ACIDIC PROTEIN; GRAFT REJECTION; GRAFT SURVIVAL; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; NEUROGLIA; RATS; SPINAL CORD; TRANSPLANTATION, HETEROLOGOUS; WALLERIAN DEGENERATION;

EID: 0031960921     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(97)00582-4     Document Type: Article

References (60)

1. Auchincloss H. Jr. Xenogeneic transplantation: a review. Transplantation. 46:1988;1-20.
2. Auchincloss H. Jr., Sultan H. Antigen processing and presentation in transplantation. Transplantation. 8:1996;681-687.
3. Benichou G., Takizawa P. A., Olson C. A., McMillan M., Sercarz E. Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J. exp. Med. 175:1992;305-308.
4. Bishop C. E., Boursot O., Baron B., Bonhonn F., Hatat D. Most classical Mus Musculus domesticus laboratory mouse strains carry a Mus Musculus musculus Y chromosome. Nature. 315:1985;70-73.
5. Blakemore W. F., Crang A. J. The relationship between type-1 astrocytes, Schwann cells and oligodendrocytes following transplantation of glial cell cultures into demyelinating lesions in the adult rat spinal cord. J. Neurocytol. 18:1989;519-528.
6. Bontrop R. E., Elferink D. G., Otting N., Jonker M., de Vries R. R. P. Major histocompatibility complex class II-restricted antigen presentation across a species barrier: conservation of restriction determinants in evolution. J. exp. Med. 172:1990;53-59.
7. Burdick J. F. Strong cellular immune responses induced in vivo against minor antigens in the mouse. Immunology. 58:1986;615-620.
8. Campos L., Naji A., Deli B. C., Kern J. H., Kim J. I., Barker C. F., Markmann J. F. Survival of MHC-deficient mouse heterotopic cardiac allografts. Transplantation. 59:1995;187-191.
9. Cardell S., Merkenschlager M., Bodmer H., Chan S., Cosgrove D., Benoist C., Mathis D. The immune system of mice lacking conventional MHC class II molecules. Adv. Immun. 55:1994;423-440.
10. Chen W., Murphy B., Waaga A. M., Willett T. A., Russell M. E., Khoury S. J., Sayegh M. H. Mechanisms of indirect allorecognition in graft rejection. Transplantation. 62:1996;705-710.
11. Cosgrove D., Gray D., Dierich A., Kaufman J., Lemeur M., Benoist C., Mathis D. Mice lacking MHC class-II molecules. Cell. 66:1991;1051-1066.
12. Daar A. S., Fuggle S. V., Fabre J. W., Ting A., Morris P. J. The detailed distribution of HLA-A, B, C antigens in normal human organs. Transplantation. 38:1984;287-292.
13. Daar A. S., Fuggle S. V., Fabre J. W., Ting A., Morris P. J. The detailed distribution of MHC class II antigens in normal human organs. Transplantation. 38:1984;293-298.
14. Doody D. P., Stenter K. S., Winn H. J. Immunologically nonspecific mechanisms of tissue destruction in the rejection of skin grafts. J. exp. Med. 179:1994;1645-1652.
15. Essers J., DeStoppelaar J. M., Hoebee B. A new rat repetitive DNA family shows preferential localization on chromosome-3, chromosome-12 and chromosome Y after fluorescence in situ hybridization and contains a subfamily which is Y-chromosome specific. Cytogen. Cell Gen. 69:1995;246-252.
16. Fangmann J., Dalchau R., Sawyer G. J., Priestley C. A., Fabre J. W. T cell recognition of donor major histocompatibility complex class I peptides during allograft rejection. Eur. J. Immun. 22:1992;1525-1529.
17. Ferguson B., Matyszak M. K., Esiri M. M., Perry V. H. Axonal damage in acute multiple sclerosis lesions. Brain. 120:1997;393-399.
18. Finsen B., Poulsen P. H., Zimmer J. Xenografting of fetal mouse hippocampal tissue to the brain of adult rats: effects of Cyclosporin A treatment. Expl Brain Res. 70:1988;117-133.
19. Finsen B., Oteruelo F., Zimmer J. Immunocytochemical characterization of the cellular immune response to intracerebral xenografts of brain tissue. Prog. Brain Res. 78:1988;261-270.
20. Finsen B. R., Pederson E. B., Sorensen T., Hokland M., Zimmer J. Immune reactions against intracerebral murine xenografts of fetal hippocampal tissue and cultured cortical astrocytes in the adult rat. Prog. Brain Res. 82:1990;111-128.
21. Finsen B. R., Sorensen T., Gonzalez B., Castellano B., Zimmer J. Immunological reactions to neural grafts in the central nervous system. Rest. Neurol. Neurosci. 2:1991;271-282.
22. Franklin R. J. M., Crang A. J., Blakemore W. F. Type 1 astrocytes fail to inhibit Schwann cell remyelination of CNS axons in the absence of cells of the O-2A lineage. Devl Neurosci. 14:1992;85-92.
23. Gill R. G., Coulombe M. Rejection of pancreatic islet xenograafts does not require CD8+ T-lymphocytes. Transplant. Proc. 24:1992;2877-2878.
24. Gill R. G., Wolf L., Daniel D., Coulombe M. CD4+ T cells are both necessary and sufficient for islet xenograft rejection. Transplant. Proc. 26:1994;1203.
25. Gill R. G., Wolf L. Immunobiology of cellular transplantation. Cell Transplant. 4:1995;361-370.
26. Grusby M. J., Johnson R. S., Papaioannou V. E., Glimcher L. H. Depletion of CD4+ T-cells in major histocompatibility complex class-II deficient mice. Science. 253:1991;1417-1420.
27. Grusby M. J., Glimcher L. H. Immune responses in MHC class II-deficient mice. A. Rev. Immun. 13:1995;417-435.
28. Hart D. N. J., Fabre J. W. Demonstration and characterization of Ia-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, but not brain. J. exp. Med. 154:1981;347-361.
29. Heath W. R., Hurd M. E., Carbone F. R., Sherman L. A. Peptide dependent recognition of H-2b by alloreactive cytotoxic T lymphocytes. Nature. 341:1989;749-752.
30. Irintchev A., Zweyer M., Wernig A. Cellular and molecular reactions in mouse muscles after myoblast implantation. J. Neurocytol. 24:1995;319-331.
31. Kaufman C. L., Gaines B. A., Ildstad S. Xenotransplantation. A. Rev. Immun. 13:1995;339-367.
32. Kievits F., Wijffels J., Lokhorst W., Ivanyi P. Recognition of xeno-(HLA, SLA) major histocompatibility complex antigens by mouse cytotoxic T cells is not H-2 restricted: a study with transgenic mice. Proc. natn. Acad. Sci. U.S.A. 86:1989;617-620.
33. Koller B. H., Smithies O. Inactivating the beta-2-microglobulin locus in mouse embryonic stem-cells by homologous recombination. Proc. natn. Acad. Sci. U.S.A. 86:1989;8932-8935.
34. Kontgen F., Suss G., Steward C., Steinmetz M., Bluethmann H. Targetted disruption of the MHC Class-II AA gene in C57Bl/6 mice. Int. Immun. 5:1993;957-964.
35. Lechler R. I., Batchelor J. R. Restoration of immungenicity to passenger cell-depleted kidney allografts by the additon of donor strain dendritic cells. J. exp. Med. 155:1982;31-41.
36. Lechler R. I., Bal V., Rothbard J. B., Germain R. N., Sekaly R., Long E. O., Lamb J. Structural and functional studies of HLA-DR restricted antigen recognition by human helper T lymphocyte clones by using transfected murine cell lines. J. Immun. 1413:1988;3003-3009.
37. Li X. P., Faustman D. Use of donor beta-2-microglobulin-deficient transgenic mouse liver cells for isografts, allografts, and xenografts. Transplantation. 55:1993;940-946.
38. Litchfield T. M., Whiteley S. J. O., Yee K. T., Tyers P., Usherwook E. J., Nash A. A., Lund R. D. Characterisation of the immune response in a neural xenograft rejection paradigm. J. Neuroimmunol. 73:1997;135-144.
39. Liu Z., Braunstein N. S., Suciu-Foca N. T cell recognition of allopeptides in context of syngeneic MHC. J. Immun. 148:1992;35-40.
40. Lombardi G., Sidhu S., Baatchelor J. R., Lechler R. I. Allorecognition of DR1 by T cells from a DR4/DRw13 responder mimics self-restricted recognition of endogenous peptides recombination. Proc. natn. Acad. Sci. U.S.A. 86:1989;4190-4194.
41. Markmann J. F., Bassiri H., Desai N. M., Odorico J. S., Kim J. I., Koller B. H., Smithies O., Barker C. F. Indefinite survival of MHC class I-deficient murine pancreatic-islet allografts. Transplantation. 54:1992;1085-1089.
42. Markmann J. F., Campos L., Bhandoola A., Kim J. I., Desai N. M., Bassiri H., Claytor B. R., Barker C. F. Genetically engineered grafts to study xenoimmunity: a role for indirect antigen presentation in the destruction of major histocompatibility complex antigen deficient xenografts. Surgery. 116:1994;242-249.
43. Mason D. W., Charlton H. M., Jones A. J., Lavy C. B. D., Puklavec M., Simmonds S. J. The fate of allogeneic and xenogeneic neuronal tissue transplanted into the third ventricle of rodents. Neuroscience. 19:1986;685-694.
44. Matyszak M. K., Perry V. H. Demyelination in the central nervous system following a delayed-type hypersensitivity response to Bacillus Calmette-Guerin. Neuroscience. 64:1995;967-977.
45. Matzinger P. Tolerance, danger, and the extended family. A. Rev. Immun. 12:1994;991-1045.
46. O'Leary M. T., Blakemore W. F. Oligodendrocyte precursors survive poorly and do not migrate following transplantation into the normal adult central nervous system. J. Neurosci. Res. 48:1997;159-167.
47. O'Leary M. T., Blakemore W. F. Use of a rat Y chromosome probe to determine the long-term survival of glial cells transplanted into areas of CNS demyelination. J. Neurocytol. 26:1997;191-206.
48. Pierres M., Marchetto S., Naquet P. M., Landais D., Peccoud J., Benoit C., Mathis D. I-Aa polymorphic residues that determine alloreactive T cell recognition. J. exp. Med. 169:1989;1655-1668.
49. Pierson R. N. III, Winn H. J., Russell P. S., Auchincloss H. Jr. Xenogeneic skin graft rejection is especially dependent on CD4+ T cells. J. exp. Med. 170:1989;991-996.
50. Raulet D. H. MHC Class I-deficient mice. Adv. Immun. 55:1994;381-421.
51. Sloan D. J., Baker B. J., Puklavec M., Charlton H. M. The effect of site of transplantation and histocompatibility differences on the survival of neural tissue transplanted to the CNS of defined inbred rat strains. Prog. Brain Res. 82:1990;141-152.
52. Takei K., Nakano Y., Shinozaki T., Toya S., Tsukada Y., Kohsaka S. Immunological rejection of grafted tissue in xenogeneic neural transplantation. Prog. Brain Res. 82:1990;103-109.
53. Vass K., Lassmann H. Intrathecal application of interferon gamma: progressive appearance of MHC antigens within the rat nervous system. Am. J. Path. 137:1990;789-800.
54. Wecker H., Winn H., Auchincloss H. J. CD4+ T cells, without CD8+ or B lymphocytes, can reject xenogeneic skin grafts. Xenotransplantation. 1:1994;8-16.
55. Wernig A., Irintchev A. "Bystander" damage of host muscle caused by implantation of MHC-compatible myogenic cells. J. neurol. Sci. 130:1995;190-196.
56. 2-microglobulin in frozen and formaldehyde-fixed central nervous tissues: comparison of tissue behind the blood-brain barrier and tissue in a barrier-free region. J. Immun. 137:1986;2561-2566.
57. Wong G. H. W., Bartlett P. F., Clark-Lewis I., McKimm-Breschkin J. L., Schrader J. W. Interferon-G induces the expression of H-2 and Ia antigens on brain cells. J. Neuroimmunol. 7:1985;255-278.
58. Wood M. J. A., Sloan D. J., Wood K. J., Charlton H. M. Indefinite survival of neural xenografts induced with anti-CD4 monoclonal antibodies. Neuroscience. 70:1996;589-775.
59. Zijlstra M., Li E., Sajjadi F., Subramani S., Jaenisch R. Germ-line transmission of a disrupted beta-2-microglobulin gene produced by homologous recombination in embryonic stem-cells. Nature. 342:1989;435-438.
60. Zijlstra M., Auchincloss H. J., Loring J. M., Chase C. M., Russell P. S., Jaenisch R. Skin-graft rejection by beta-2-microglobulin-deficient mice. J. exp. Med. 175:1992;885-893.