Selection of novel ligands from phage display libraries: An alternative approach to drug and vaccine discovery?

Parasitology Today

Volumn 14, Issue 5, 1998, Pages 202-206

  Jefferies, D ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; BACTERIOPHAGE; DNA LIBRARY; HOST PARASITE INTERACTION; NONHUMAN; PHAGE DISPLAY; PROTEIN DOMAIN; REVIEW; TECHNIQUE; VACCINE PRODUCTION;

EID: 0031959363     PISSN: 01694758     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-4758(98)01221-6     Document Type: Article

References (42)

1. Parmley S.F., Smith G.P. Antibody-selectable filamentous fd phage vectors: affinity purification of target genes. Gene. 73:1988;305-318.
2. Cwirla S.E.et al. Peptides on phage: A vast library of peptides for identifying ligands. Proc. Natl. Acad. Sci. U. S. A. 87:1990;6378-6382.
3. Scott J.K., Smith G.P. Searching for peptide ligands with an epitope library. Science. 245:1990;386-390.
4. Devlin J.J.et al. Random peptide libraries: a source of specific protein binding molecules. Science. 249:1990;404-406.
5. Winter J. Bacteriophage display: peptide libraries and drug discovery. Drug Dev. Res. 33:1994;71-89.
6. Gram H.et al. Phage display as a rapid gene expression system: production of bioactive cytokine-phage and generation of neutralizing monoclonal antibodies. J. Immunol. Methods. 161:1993;169-176.
7. Winter G.et al. Making antibodies by phage display technology. Annu. Rev. Immunol. 12:1994;433-455.
8. Griffiths A.D.et al. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13:1994;3245-3260.
9. Crameri R., Blaser K. Cloning Aspergillus fumigatus allergens by the pJuFo filamentous phage display system. Int. Arch. Allergy Immunol. 110:1996;41-45.
10. Jespers L.S.et al. Surface expression and ligand-based selection of cDNAs fused to filamentous phage gene VI. Bio/Technology. 13:1995;378-382.
11. de la Cruz V.F.et al. Immunogenicity and epitope mapping of foreign sequences via genetically engineered filamentous phage. J. Biol. Chem. 263:1988;4318-4322.
12. Clackson T.et al. Making antibody fragments using phage display libraries. Nature. 352:1991;624-628.
13. Matthews D.J., Wells J.A. Substrate phage: selection of protease substrates by monovalent phage display. Science. 260:1993;1113-1117.
14. O'Neil K.T.et al. Identification of recognition sequences of adhesion molecules using phage display technology. Methods Enzymol. 245:1994;370-386.
15. Choo Y.et al. In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence. Nature. 372:1994;642-645.
16. Jacobsson K., Frykberg J. Phage display shot-gun cloning of ligand-binding domains of prokaryotic receptors approaches 100% correct clones. BioTechniques. 20:1996;1070-1081.
17. O'Neil K.T., Hoess R.H. Phage display: protein engineering by directed evolution. Curr. Opin. Struct. Biol. 5:1995;443-449.
18. Scott J.K. Discovering peptide ligands using epitope libraries. Trends Biochem. Sci. 17:1992;241-245.
19. Houghten R.A. Peptide libraries: criteria and trends. Trends Genet. 9:1993;235-239.
20. Gold L.et al. Diversity of oligonucleotide functions. Annu. Rev. Biochem. 64:1995;763-797.
21. Service R.F. Combinatorial chemistry hits the drug market. Science. 272:1996;1266-1268.
22. Abelson, J.N., ed. (1996) Methods in Enzymology. Vol. 267. Combinatorial Chemistry, Academic Press.
23. Kay, B.K. et al., eds (1996) Phage Display of Peptides and Proteins, Academic Press.
24. Felici F.et al. Selection of antibody ligands from a large library of oligopeptides expressed on a multivalent exposition vector. J. Mol. Biol. 222:1991;301-310.
25. Makowski L. Phage display: structure, assembly and engineering of filamentous bacteriophage M13. Curr. Opin. Struct. Biol. 4:1994;225-230.
26. Smith G.P. Surface presentation of protein epitopes using bacteriophage expression systems. Curr. Opin. Biotechnol. 2:1991;668-672.
27. McConnell S.J.et al. Constrained peptide libraries as a tool for finding mimotopes. Gene. 151:1994;115-118.
28. Sternberg N., Hoess R.H. Display of peptides and proteins on the surface of bacteriophage λ Proc. Natl. Acad. Sci. U. S. A. 92:1995;1609-1613.
29. Greenwood J.et al. Multiple display of foreign peptides on a filamentous bacteriophage - peptides from Plasmodium falciparum circumsporozoite protein as antigens. J. Mol. Biol. 220:1991;821-827.
30. Willis A.E.et al. Immunological properties of foreign peptides in multiple display on a filamentous bacteriophage. Gene. 128:1993;79-83.
31. Barbas C.F. IIIet al. High-affinity self-reactive human antibodies by design and selection: Targeting the integrin ligand binding site. Proc. Natl. Acad. Sci. U. S. A. 90:1993;10003-10007.
32. Deng S.J.et al. Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries. Proc. Natl. Acad. Sci. U. S. A. 92:1995;4992-4996.
33. Scott J.K.et al. A family of concanavalin A-binding peptides from a hexapeptide epitope library. Proc. Natl. Acad. Sci. U. S. A. 89:1992;5398-5402.
34. Oldenburg K.R.et al. Peptide ligands for a sugar-binding protein isolated from a random peptide library. Proc. Natl. Acad. Sci. U. S. A. 89:1992;5393-5397.
35. Harris S.L.et al. Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. Proc. Natl. Acad. Sci. U. S. A. 94:1997;2454-2459.
36. Schenkman S.et al. A novel cell surface trans-sialidase of Trypanosoma cruzi generates a stage-specific epitope required for invasion of mammalian cells. Cell. 65:1991;1117-1125.
37. Welburn S.C.et al. Mid-gut lectin activity and sugar specificity in teneral and fed tsetse. Med. Vet. Entomol. 8:1994;81-87.
38. Folgori A.et al. A general strategy to identify mimotopes of pathological antigens using only random peptide libraries and human sera. EMBO J. 13:1994;2236-2243.
39. Goodson R.J.et al. High-affinity urokinase receptor antagonists identified with bacteriophage peptide display. Biochemistry. 91:1994;7129-7133.
40. Fong S.et al. Scanning whole cells with phage-display libraries: identification of peptide ligands that modulate cell function. Drug Dev. Res. 33:1994;64-70.
41. Pasqualini R., Ruosiahti E. Organ targeting in vivo using phage display peptide libraries. Nature. 380:1996;364-366.
42. Laird-Offringa I.A., Belasco J.G. In vitro genetic analysis of RNA-binding proteins using phage display libraries. Methods Enzymol. 267:1996;149-168.