Heterogeneity of p53 mutational status in esophageal squamous cell carcinoma

Japanese Journal of Cancer Research

Volumn 89, Issue 4, 1998, Pages 405-410

  Kuwabara, Shirou ^a,b   Ajioka, Yoichi ^a   Watanabe, Hidenobu ^a   Hitomi, Jiro ^a   Nishikura, Ken ^a   Hatakeyama, Katsuyoshi ^a  

^a NIIGATA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

Author keywords

Esophageal cancer; Hererogeneity; p53

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; ESOPHAGUS CARCINOMA; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC HETEROGENEITY; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

EID: 0031959257     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1998.tb00578.x     Document Type: Article

References (40)

1. Wainscoat, J. S. and Fey, M. F. Assessment of clonality in human tumors: a review. Cancer Res., 50, 1355-1360 (1990).
2. Nigro, J. M., Baker, S. J., Preisinger, A. C., Jessup, J. M., Hostetter, R., Cleary. K., Bigner, S. H., Davidson, N., Baylin, S., Devilee, P., Glover, T., Collins, F. S., Weston, A., Modali, R., Harris, C. C. and Vogelstein, B. Mutations in the p53 gene occur in diverse human tumour types. Nature, 342, 705-708 (1989).
3. Hollstein, M., Sidransky, D., Vogelstein, B. and Harris, C. C. p53 mutations in human cancers. Science, 253, 49-53 (1991).
4. Baker, S. J., Fearon, E. R., Nigro, J. M., Hamilton, S. R., Preisinger, A. C., Jessup, J. M., van Tuinen, P., Ledbetter, D. H., Barker, D. F., Nakamura, Y., White, R, and Vogelstein, B. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science, 244, 217-221 (1989).
5. Harris, C. C. and Hollstein, M. Clinical implications of the p53 tumor-suppressor gene. N. Engl. J. Med., 329, 1318-1327 (1993).
6. Vogelstein, B. and Kinzler, K. W. p53 function and dysfunction. Cell, 70, 523-526 (1992).
7. Fearon, E. R. and Vogelstein, B. A genetic model for colorectal tumorigenesis. Cell, 61, 759-767 (1990).
8. Shirasawa, S., Urabe, K., Yanagawa, Y., Toshitani, K., Iwama, T. and Sasuzuki, T. p53 gene mutations in colorectal tumors from patients with familial polyposis coli. Cancer Res., 51, 2874-2878 (1991).
9. Ohue, M., Tomita, N., Monden, T., Fujita, M., Fukunaga, M., Takami, K., Yana, I., Ohnishi, T., Enomoto, T., Inoue, M., Shimano, T. and Mori, T. A frequent alteration of p53 gene in carcinoma in adenoma of colon. Cancer Res., 54, 4798-4804 (1994).
10. Ito, T., Seyama, T., Mizuno, T., Tsuyama, N., Hayashi, T., Hayashi, Y., Dohi, K., Nakamura, N. and Akiyama, M. Unique association of p53 mutations with undifferentiated but not with differentiated carcinomas of the thyroid gland. Cancer Res., 52, 1369-1371 (1992).
11. Mazars, R., Pujol, P., Maudelonde, T., Jeanteur, P. and Theillet, C. p53 mutations in ovarian cancer: a late event? Oncogene, 6, 1685-1690 (1991).
12. Murakami, Y., Hayashi, K., Hirohashi, S. and Sekiya, T. Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. Cancer Res., 51, 5520-5525 (1991).
13. Ohgaki, H., Eibl, R. H., Schwab, M., Reichel, M. B., Mariani, L., Gehring, M., Petersen, I., Holl, T., Wiestler, O. D. and Kleihues, P. Mutations of the p53 tumor suppressor gene in neoplasms of the human nervous system. Mol. Carcinog., 8, 74-80 (1993).
14. Ohgaki, H., Kleihues, P. and Heitz, P. U. p53 mutations in sporadic adrenocortical tumors. Int. J. Cancer, 54, 408-410 (1993).
15. Davidoff, A. M., Kerns, B. J., Iglehart, J. D. and Marks, J. R. Maintenance of p53 alterations throughout breast cancer progression. Cancer Res., 51, 2605-2610 (1991).
16. Imazeki, F., Omata, M., Nose, H., Ohto, M. and Isono, K. p53 gene mutations in gastric and esophageal cancers. Gastroenterology, 103, 892-896 (1992).
17. Wagata, T., Shibagaki, I., Imamura, M., Shimada, Y., Toguchida, J., Yandell, D. W., Ikenaga, M., Tobe, T. and Ishizaki, K. Loss of 17p, mutation of the p53 gene, and overexpression of p53 protein in esophageal squamous cell carcinomas. Cancer Res., 53, 846-850 (1993).
18. Wang, L. D., Zhou, Q., Hong, J. Y., Qiu, S. L. and Yang, C. S. p53 protein accumulation and gene mutations in multifocal esophageal precancerous lesions from symptom free subjects in a high incidence area for esophageal carcinoma in Henan, China. Cancer, 77, 1244-1249 (1996).
19. Bennett, W. P., Hollstein, M. C., Metcalf, R. A., Welsh, J. A., He, A., Zhu, S. M., Kusters, I., Resau, J. H., Trump, B. F., Lane, D. P. and Harris, C. C. p53 mutation and protein accumulation during multistage human esophageal carcinogenesis. Cancer Res., 52, 6092-6097 (1992).
20. Gao, H., Wang, L.-D., Zhou, Q., Hong, J.-Y., Huang, T.-Y. and Yang, C. S. p53 tumor suppressor gene mutation in early esophageal precancerous lesions and carcinoma among high-risk populations in Henan, China. Cancer Res., 54, 4342-4346 (1994).
21. Parenti, A. R., Rugge, M., Frizzera, E., Ruol, A., Noventa, F., Ancona, E. and Ninfo, V. p53 overexpression in the multistep process of esophageal carcinogenesis. Am. J. Surg. Pathol., 19, 1418-1422 (1995).
22. Japanese Society for Esophageal Diseases. "Guide Line for the Clinical and Pathologic Studies on Carcinoma of the Esophagus," 8th Ed. (1992). Kanehara Co., Tokyo.
23. Oohashi, Y., Watanabe, H., Ajioka, Y. and Hatakeyama, K. p53 immunostaining distinguishes malignant from benign lesions of the gallbladder. Pathol. Intern., 45, 58-65 (1995).
24. Watanabe, H., Nakagawa, S., Endo, Y., Nishikura, K. and Ajioka, Y. Histological diagnosis of carcinoma in situ and dysplasia of esophageal squamous cell carcimoma. Stomach Intest., 30, 407-416 (1995)(in Japanese).
25. Nakagawa, S., Watanabe, H., Ajioka, Y., Nishikura, K., Hitomi, J. and Hatakeyama, K. Archival analysis of p53 protein overexpression and genetic mutation in esophageal squamous cell carcimona. Acta Med. Biol., 44, 63-69 (1996).
26. Watson, J. D., Witkowski, J., Gilman, M. and Zoller, M. "Recombinant DNA," 2nd Ed., p. 92 (1992). W. H. Freeman and Co., New York.
27. Sanger, F., Nicklen, S. and Coulson, A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA, 74, 5463-5467 (1977).
28. Nagel, S., Borisch, B., Thein, S. L., Oestreicher, M., Nothiger, F., Birrer, S., Tobler, A. and Fey, M. F. Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intratumor heterogeneity in gastrointestinal cancers. Cancer Res., 55, 2866-2870 (1995).
29. Hori, H., Miyake, S., Akiyama, Y., Endo, M. and Yuasa, Y. Clonal heterogeneity in human esophageal squamous cell carcinomas on DNA analysis. Jpn. J. Cancer. Res., 87, 923-929 (1996).
30. Mayama, T., Mori, T., Abe, K., Sasano, H., Nishihira, T., Satomi, S. and Horii, A. Analysis of the p53 gene mutations in patients with multiple primary cancers of the oesophagus. Eur. J. Surg. Oncol., 23, 298-303 (1997).
31. Slaughter, D. P., Southwick, H. W. and Smejkal, W. "Field cancerization" in oral stratified squamous epithelium. Cancer, 6, 693-698 (1953).
32. Nees, M., Homann, N., Discher, H., Andl, T., Enders, C., Herold-Mende, C., Schuhmann, A. and Bosch, F. X. Expression of mutated p53 occurs in tumor-distant epithelia of head and neck cancer patients: a possible molecular basis for the development of multiple tumors. Cancer Res., 53, 4189-4196 (1993).
33. Chung, K. Y., Mukhopadhyay, T., Kim, J., Casson, A., Ro, J. Y., Goepfert, H., Hong, W. K. and Roth, J. A. Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract. Cancer Res., 53, 1676-1683 (1993).
34. Califano, J., van der Riet, P., Westra, W., Nawroz, H., Clayman, G., Piantadosi, S., Corio, R., Lee, D., Greenberg, B., Koch, W. and Sidransky, D. Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res., 56, 2493-2496 (1996).
35. Sozzi, G., Miozzo, M., Donghi, R., Pilotti, S., Cariani, C. T., Pastorino, U., Porta, G. D. and Pierotti, M. A. Deletions of 17p and p53 mutations in preneoplastic lesions of the lung. Cancer Res., 52, 6079-6082 (1992).
36. Li, Z.-H., Zheng, J., Weiss, L. M. and Shibata, D. c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung. Am. J. Pathol. 144, 303-309 (1994).
37. Reichel, M. B., Ohgaki, H., Petersen, I. and Kleihues, P. p53 mutations in primary human lung tumors and their metastases. Mol. Carcinog., 9, 105-109 (1994).
38. Shibata, D., Schaeffer, J., Li, Z. H., Capella, G. and Perucho, M. Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas. J. Natl. Cancer Inst., 85, 1058-1063 (1993).
39. Baker, S. J., Markowitz, S., Fearon, E. R., Willson, J. K. and Vogelstein, B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science, 249, 912-915 (1990).
40. Roth, J. A., Nguyen, D., Lawrence, D. D., Kemp, B. L., Carrasco, C. H., Ferson, D. Z., Hong, W. K., Komaki, R., Lee, J. J., Nesbitt, J. C., Pisters, K. M., Putnam, J. B., Schea, R., Shin, D. M., Walsh, G. L., Dolormente, M. M., Han, C. I., Martin, F. D., Yen, N., Xu, K., Stephens, L. C., McDonnell, T. J., Mukhopadhyay, T. and Cai, D. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Nat. Med., 2, 985-991 (1996).