Application of tumbling melt granulation method to prepare controlled- release beads by coating with mixture of functional non-meltable and meltable materials

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 3, 1998, Pages 531-533

  Maejima, Toru ^a   Osawa, Takashi ^a   Nakajima, Kingo ^a   Kobayashi, Masao ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Beads; Centrifugal fluidizing granulator; Controlled release; Functional powder; Tumbling melt granulation; Wax

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE ACETATE SUCCINATE; MAGNESIUM STEARATE; NICOTINAMIDE; POLYMER; TALC; WETTING AGENT;

ARTICLE; CONTROLLED RELEASE FORMULATION; DRUG COATING; DRUG GRANULATION; DRUG SOLUBILITY; DRUG STABILITY; GEL; HEATING; TECHNIQUE; THERMOSTABILITY;

EID: 0031957906     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.531     Document Type: Article

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