Protein kinase C-ε is implicated in neurite outgrowth in differentiating human neuroblastoma cells

Cell Growth and Differentiation

Volumn 7, Issue 6, 1996, Pages 775-785

  Fagerström, Sofia ^a,b   Påhlman, Sven ^a,b   Gestblom, Carolina ^a,b   Nånberg, Eewa ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH ASSOCIATED PROTEIN; GROWTH FACTOR; NEUROPEPTIDE Y; PROTEIN KINASE C;

ARTICLE; CELL DIFFERENTIATION; ENZYME ACTIVITY; GENE EXPRESSION; GROWTH CONE; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; NEUROBLASTOMA CELL; PRIORITY JOURNAL;

CELL DIFFERENTIATION; DOWN-REGULATION; ENZYME INHIBITORS; GROWTH SUBSTANCES; HUMANS; INDOLES; ISOENZYMES; MALEIMIDES; NEURITES; NEUROBLASTOMA; NEURONS; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-EPSILON; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC;

EID: 0029834397     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Påhlman, S., Odelstad, L., Larsson, E., Grotte, G., and Nilsson, K. Phenotypic changes of human neuroblastoma cells in culture induced by 12-tetradecanoyl-phorbol-13-acetate. Int. J. Cancer, 28: 583-589, 1981.
2. Påhlman, S., Ruusala, A-I., Abrahamsson, L., Odelstad, L., and Nilsson, K. Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells. Cell Differ., 12: 165-170, 1983.
3. Lavenius, E., Parrow, V., Nånberg, E., and Påhlman, S. Basic FGF and IGF-1 promote differentiation of human SH-SY5Y neuroblastoma cells in culture. Growth Factors, 10: 29-39, 1994.
4. Påhlman, S., Meyerson, G., Lindgren, E., Schalling, M., and Johansson, I. Insulin-like growth factor-1 shifts from promoting cell division to potentiating maturation during neuronal differentiation. Proc. Natl. Acad. Sci. USA, 88: 9994-9998, 1991.
5. Påhlman, S., Johansson, I., Westermark, B., and Nistér, M. Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells. Cell Growth & Differ., 3: 783-790, 1992.
6. Lavenius, E., Gestblom, C., Johansson, I., Nånberg, E., and Påhlman, S. Transfection of TRK-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor. Cell Growth & Differ., 6: 727-736, 1995.
7. Poluha, W., Poluha, D. K., and Ross, A. H. TrkA neurogenic receptor regulates differentiation of neuroblastoma cells. Oncogene, 10: 185-189, 1995.
8. c-srcN and a 38-kDa protein is highly enriched in growth cones from differentiated SH-SY5Y human neuroblastoma cells. J. Cell Sci., 103: 233-243, 1992.
9. c-srcN. FEBS Lett., 332: 27-30, 1993.
10. Nakamura, S., and Nishizuka, Y. Lipid mediators and protein kinase C activation for the intracellular signaling network. J. Biochem. (Tokyo), 115: 1029-1034, 1994.
11. Nishizuka, Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science (Washington DC), 258: 607-614, 1992.
12. Stabel, S., and Parker, P. J. Protein kinase C. Pharmacol. & Ther., 51: 71-95, 1991.
13. Ha, K-S., and Exton, J. H. Differential translocation of protein kinase C isozymes by thrombin and platelet-derived growth factor. J. Biol. Chem., 263: 10534-10539, 1993.
14. Dekker, L. V., and Parker, P. J. Protein kinase C: a question of specificity. Trends Biochem. Sci., 19: 73-77, 1994.
15. Parrow, V., Fagerström, S., Meyerson, G., Nånberg, E., and Påhlman, S. Protein kinase C-α and -ε are enriched in growth cones of differentiating SH-SY5Y human neuroblastoma cells. J. Neurosci. Res., 41: 782-791, 1995.
16. Parrow, V., Nånberg, E., Heikkilä, J., Hammerting, U., and Påhlman, S. Protein kinase C remains functionally active during TPA induced neuronal differentiation of SH-SY5Y human neuroblastoma cells. J. Cell. Physiol., 152: 536-544, 1992.
17. Toullec, D., Pianetti, P., Coste, H., Bellevergue, P., Grand-Perret, T., Ajakane, M., Baudet, V., Boissin, P., Boursier, E., Loriolle, F., Duhamel, L., Charon, D., and Kirilovsky, J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem., 266: 15771-15781, 1991.
18. Leli, U., Parker, P. J., and Shea, T. B. Intracellular delivery of protein kinase C-α or -ε isoform-specific antibodies promotes acquisition of a morphologically differentiated phenotype in neuroblastoma cells. FEBS Lett., 297: 91-94, 1992.
19. Shea, T. B., Beermann, M. L., Leli, U., and Nixon, R. A. Opposing influences of protein kinase activities on neurite outgrowth in human neuroblastoma cells: initiation by kinase A and restriction by kinase C. J. Neurosci. Res., 33: 398-407, 1992.
20. Heikkilä, J., Jalava, A., and Eriksson, K. The selective protein kinase C inhibitor GF 109203X inhibits phorbol ester-induced morphological and functional differentiation of SH-SY5Y human neuroblastoma cells. Biochem. Biophys. Res. Commun., 197: 1185-1193, 1993.
21. Smith, S. J. Neuronal cytomechanics: the actin-based motility of growth cones. Science (Washington DC), 242: 708-715, 1988.
22. Apgar, J. R. Regulation of the antigen-induced F-actin response in rat basophilic leukemia cells by protein kinase C. J. Cell Biol., 112: 1157-1163, 1991.
23. Downey, G. P., Chan, C. K., Lea, P., Takai, A., and Grinstein, S. Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C. J. Biol. Chem., 116: 695-706, 1992.
24. Trachsel, S., and Keller, H. U. Selective responses (actin polymerization, shape changes locomotion, pinocytosis) to the PKC inhibitor Ro 31-8220 suggest that PKC discriminately regulates function of human blood lymphocytes. J. Leukocyte Biol., 57: 587-591, 1995.
25. Hug, H., and Sarre, T. F. Protein kinase C isoenzymes: divergence in signal transduction? Biochem. J., 291: 329-343, 1993.
26. Pears, C., and Parker, P. J. Down-regulation of a kinase defective PKC-α. FEBS Lett., 284: 120-122, 1991.
27. Helmke, S., and Pfenninger, K. H. Growth cone enrichment and cytoskeletal association of non-receptor tyrosine kinases. Cell Motil. Cytoskeleton, 30: 194-207, 1995.
28. Maness, P. F., Aubry, M., Shores, C. G., Frame, L., and Pfenninger, K. H. c-Src gene product in developing rat brain is enriched in growth cone membranes. Proc. Natl. Acad. Sci. USA, 85: 5001-5005, 1988.
29. Strittmatter, S. M., Fankhauser, C., Huang, P. L., Mashimo, H., and Fishman, M. C. Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43. Cell, 80: 445-452, 1995.
30. Aigner, L., Arber, S., Kapfhammer, J. P., Laux, T., Schneider, C., Botteri, F., Brenner, H-R., and Caroni, P. Overexpression of the neuronal growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell, 83: 269-278, 1995.
31. Widmer, F., and Caroni, P. Phosphorylation-site mutagenesis of the growth-associated protein GAP-43 modulates its effects on cell spreading and morphology. J. Cell Biol., 120: 503-512, 1993.
32. Tonetti, D. A., Henning-Chubb, C., Yamanishi, D. T., and Huberman, E. Protein kinase C-β is required for macrophage differentiation of human HL-60 leukemia cells. J. Biol. Chem., 269: 23230-23235, 1994.
33. Macfarlane, D. E., and Manzel, L. Activation of β-isozyme of protein kinase C (PKC β) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC β-defective PET mutant. J. Biol. Chem., 269: 4327-4331, 1994.
34. Cornet, M. E., Sanz, L., and Moscat, J. Evidence for a role of protein kinase C ζ subspecies in maturation of Xenopus laevis oocytes. Mol. Cell. Biol., 12: 3776-3783, 1992.
35. Berra, E., Diaz-Meco, M. T., Dominguez, I., Municio, M. M., Sanz, L., Lozano, J., Chapkin, R. S., and Moscat, J. Protein kinase C ζ isoform is critical for mitogenic signal transduction. Cell, 74: 555-563, 1993.
36. Ways, D. K., Posekany, K., deVente, J., Garris, T., Chen, J., Hooker, J., Qin, W., Cook, P., Fletcher, D., and Parker, P. Overexpression of protein kinase C-ζ stimulates leukemic cell differentiation. Cell Growth & Differ., 5: 1195-1203, 1994.
37. Liao, L., and Jaken, S. Effect of α-protein kinase C neutralizing antibodies and the pseudosubstrate peptide on phosphorylation, migration, and growth of REF52 cells. Cell Growth & Differ., 4: 309-316, 1993.
38. Liao, L., Ramsay, K., Jaken, S. Protein kinase C isozymes in progressively transformed rat embryo fibroblasts. Cell Growth & Differ., 5: 1185-1194, 1994.
39. Ahmad, S., Mineta, T., Martuza, R. L., Glazer, R. I. Antisense expression of protein kinase C-α inhibits the growth and tumorigenicity of human glioblastoma cells. Neurasurgery (Baltimore), 35: 904-909, 1994.
40. Genot, E. M., Parker, P. J., and Cantrell, D. A. Analysis of the role of protein kinase C-α-ε and -ζ in T cell activation. J. Biol. Chem., 270: 9833-9839, 1995.
41. Biedler, J., Helson, L., and Spengler, B. Morphology and growth, tumorigenicity and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res., 33: 2643-2652, 1973.
42. Biedler, J., Roffler-Tarlov, S., Schachner, M., and Freedman, L. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res., 38: 3751-3757, 1978.
43. Meyerson, G., Parrow, V., Gestblom, C., Johansson, I., and Påhlman, S. Protein synthesis and mRNA in isolated growth cones from differentiating SH-SY5Y neuroblastoma cells. J. Neurosci. Res., 37: 303-312, 1994.
44. Ranefall, P., Nordin, B., and Bengtsson, E. A new metric in colour space used for supervised and unsupervised image segmentation. In: K. Malmquist (ed.), Proceedings of Swedish Society for Automated Image Analysis: Symposium on Image Analysis, pp. 77-80. Högskolan Halmstad, Halmstad, Sweden, 1994.
45. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162: 156-159, 1987.
46. Sambrook, J., Fritsch, E., and Maniatis, T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
47. Minth, C., Andrews, P., and Dixon, J. Characterization, sequence, and expression of the cloned human neuropeptide Y gene. J. Biol. Chem., 261: 11974-11979, 1986.
48. Örtoft, E., Påhlman, S., Andersson, G., Parrow, V., Betsholtz, C., and Hammerling, U. Human GAP-43 gene expression. Multiple start sites for initiation of transcription in differentiating human neuroblastoma cells. Mol. Cell. Neurosci., 4: 549-561, 1993.
49. Tso, J., Sun, X-H., Kao, T-H., Reese, K., and Wu, R. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res., 13: 2485-2502, 1985.
50. Lowry, O., Rosebrough, N., Farr, A., and Randall, R. Protein measurement with the folin phenol reagent. J. Biol. Chem., 193: 265-275, 1951.
51. Laemmli, U. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
52. Towbin, H., Staehelin, T., and Gordon, J. Electrophoretic transfer of proteins from polyacrylamide to nitrocellulose sheets: procedures and some applications. Proc. Natl. Acad. Sci. USA, 76: 4350-4354, 1979.