Heparin inhibits thrombin-induced mitogen-activated protein kinase signaling in arterial smooth muscle cells

Journal of Vascular Surgery

Volumn 27, Issue 3, 1998, Pages 512-520

  Hedin, U ^a   Daum, G ^a   Clowes, A W ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ENDOTHELIN 1; HEPARIN; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; THROMBIN;

ANIMAL CELL; ARTERY INJURY; ARTERY INTIMA PROLIFERATION; ARTICLE; BABOON; CELL PROLIFERATION; DNA SYNTHESIS; ENZYME ACTIVATION; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SURGERY;

EID: 0031956019     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-5214(98)70326-X     Document Type: Article

References (38)

1. R Ross Cell biology of atherosclerosis Ann Rev Physiol 57 1995 791 804
2. RL Hoover R Rosenberg W Haering MJ Karnovsky Inhibition of rat arterial smooth muscle cell proliferation by heparin.II. In vitro studies Circ Res 47 1980 578 583
3. AW Clowes MJ Karnovsky Suppression by heparin of smooth muscle cell proliferation in injured arteries Nature 265 1977 625 626
4. MW Majesky SM Schwartz MM Clowes AW Clowes Heparin regulates smooth muscle S-phase entry in injured rat carotid artery Circ Res 61 1987 296 304
5. CF Reilly MS Kindy KE Brown RD Rosenberg GE Soneshein Heparin prevents vascular smooth muscle cell progression through the G1 phase of the cell cycle J Biol Chem 264 1989 6990 6995
6. JJ Castellot LA Pukac BL Caleb TC Wright MJ Karnovsky Heparin selectively inhibits a protein kinase C-dependent mechanism of cell cycle progression in calf aortic smooth muscle cells J Cell Biol 109 1989 3147 3155
7. LA Pukac ME Ottlinger MJ Karnovsky Heparin suppresses specific second messenger pathways for protooncogene expression in rat vascular smooth muscle cells J Biol Chem 267 1992 3707 3711
8. T Miralem A Wang CI Whiteside DM Templeton Heparin inhibits mitogen-activated protein kinase-dependent and -independent c-fos induction in mesangial cells J Biol Chem 271 1996 17100 17106
9. SJ Busch GA Martin RL Barnhart M Mano AD Cardin RL Jackson Trans-repressor activity of nuclear glycosaminoglycans on Fos and Jun/AP-1 oncoprotein-mediated transcription J Cell Biol 116 1992 31 42
10. V Lindner NE Olson AW Clowes MA Reidy Inhibition of smooth muscle cell proliferation in injured rat arteries. Interaction of heparin with basic fibroblast growth factor J Clin Invest 90 1992 2044 2049
11. ME Ottlinger LA Pukac MJ Karnovsky Heparin inhibits mitogen-activated protein kinase activation in intact rat vascular smooth muscle cells J Biol Chem 268 1993 19173 19176
12. MJ Robinson MH Cobb Mitogen-activated protein kinase pathways Curr Opin Cell Biol 9 1997 180 186
13. mapk (ERK1) by growth factors: correlation between late phase activation and mitogenicity Mol Biol Cell 3 1992 63 71
14. mapkk ) in fibroblasts J Cell Biol 122 1993 1079 1088
15. G Daum U Hedin T Wang Y Wang AW Clowes Diverse effects of heparin on mitogen-activated protein kinase dependent signal transduction in vascular smooth muscle cells Circ Res 81 1997 17 23
16. GR Post JH Brown G protein-coupled receptors and signaling pathways regulating growth responses FASEB J 10 1996 741 749
17. GE Deibler RE Martenson MW Kies Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species Prep Biochem 2 1972 139 165
18. DJ Robbins E Zhen H Owaki CA Vanderbilt D Ebert TD Geppert Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro J Biol Chem 268 1993 5097 5106
19. R Seger D Seger AA Reszka ES Munar H Eldar-Finkelman G Dobrowolska Overexpression of mitogen-activated protein kinase kinase (MAPKK) and its mutants in NIH 3T3 cells. Evidence that MAPKK involvement in cellular proliferation is regulated by phosphorylation of serine residues in its kinase subdomains VII and VIII J Biol Chem 269 1994 25699 25709
20. I Kameshita H Fujisawa A sensitive method for detection of calmodulin-dependent protein kinase II in sodium dodecyl sulfate-polyacrylamide gel Anal Biochem 183 1989 139 143
21. Y Gotoh E Nishida T Yamashita M Hoshi M Kawakami H Sakai Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells Eur J Biochem 193 1990 661 669
22. U Hedin S Frebelius J Sanchez M Dryjski J Swedenborg Antithrombin III inhibits thrombin-induced proliferation in human arterial smooth muscle cells Arterioscler Thromb 14 1994 254 260
23. P Chan M Patel L Betteridge E Munro M Schachter J Wolfe Abnormal growth regulation of vascular smooth muscle cells by heparin in patients with restenosis Lancet 341 1993 341 342
24. RL Geary N Koyma TW Wang S Vergel AW Clowes Failure of heparin to inhibit intimal hyperplasia in injured baboon arteries: the role of heparin-sensitive and -insensitive pathways in the stimulation of smooth muscle cell migration and proliferation Circulation 91 1995 2972 2981
25. q-mediated mitogen-activated protein kinase activation J Biol Chem 270 1995 17148 17153
26. JM Herbert M Clowes H Lea M Pascal AW Clowes Protein kinase Cα expression is required for heparin inhibition of rat smooth muscle cell proliferation in vitro and in vivo J Biol Chem 271 1996 25928 25935
27. CJ Molloy JE Pawlowski DT Taylor CE Turner H Weber M Peluso Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the Raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells J Clin Invest 97 1996 1173 1183
28. mapk are required for fibroblast proliferation Proc Natl Acad Sci USA 90 1993 8319 8323
29. mapk (ERK1) by α-thrombin and thrombin-receptor agonist peptide Biochem J 289 1993 209 214
30. CA McNamara IJ Sarembock LW Gimple JW Fenton SR Coughlin GK Owens Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor J Clin Invest 91 1993 94 98
31. G Fager Thrombin and proliferation of vascular smooth muscle cells Circ Res 77 1995 645 650
32. SM Schwartz D deBlois ER O'Brien The intima. Soil for atherosclerosis and restenosis Circ Res 77 1995 445 465
33. D Baykal JF Schmedtje MS Runge Role of thrombin receptor in restenosis and atherosclerosis Am J Cardiol 75 1995 82B 87B
34. SM Schwartz Serum-derived growth factor is thrombin? J Clin Invest 91 1993 4
35. MA Bogoyevitch A Clerk PH Sugden Activation of the mitogen-activated protein kinase cascade by pertussistoxin-sensitive and -insensitive pathways in cultured ventricular cardiomyocytes Biochem J 309 1995 437 443
36. JL Duff MB Marrero WG Paxton B Schieffer KE Bernstein BC Berk Angiotensin II signal transduction and the mitogen-activated protein kinase pathway Cardiovasc Res 30 1995 511 517
37. JS Powell JP Clozel RK Muller H Kuhn F Hefti M Hosang Inhibitors of angiotensin-converting enzyme prevent myointimal proliferation after vascular injury Science 245 1989 186 188
38. IJ Sarembock SD Gertz LW Gimple RM Owen ER Powers WC Roberts Effectiveness of recombinant desulphatohirudin (CGP 39393) in reducing restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits Circulation 84 1991 232 243