Stimulus dependence of oxygenation-sensitive MRI responses to sustained visual activation

NMR in Biomedicine

Volumn 11, Issue 2, 1998, Pages 75-79

  Kruger G ^a   Kleinschmidt, A ^a   Frahm, J ^a  

^a Biomedizinische NMR Forschungs GmbH   (Germany)

Author keywords

Functional anatomy; Human brain; Magnetic resonance imaging; Oxidative metabolism; Visual responses

Indexed keywords

ADULT; ARTICLE; BLOOD OXYGENATION; BRAIN OXYGEN CONSUMPTION; CONTRAST; CONTROLLED STUDY; DARKNESS; HUMAN; HUMAN EXPERIMENT; LIGHT EXPOSURE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; VISUAL STIMULATION;

ADULT; BRAIN MAPPING; HEMOGLOBINS; HUMANS; MAGNETIC RESONANCE IMAGING; OXYGEN; PHOTIC STIMULATION; TIME FACTORS; VISUAL CORTEX;

EID: 0031955871     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199804)11:2<75::AID-NBM504>3.0.CO;2-7     Document Type: Article

References (18)

1. Hathout G. M., Kirlew K. A. T., So G. J. K., Hamilton D. R., Zhang J. X., Sinha U., Sinha S., Sayre J., Gozal D., Harper R. M. and Lufkin R. B. MR imaging signal response to sustained stimulation in human visual cortex. J. Magn. Reson. Imag. 4, 537-543 (1994).
2. Frahm J., Krüger G., Merboldt K. D. and Kleinschmidt A. Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man. Magn. Reson. Med. 35, 143-148 (1996).
3. Bandettini P. A., Davis T. L., Kwong K. K., Fox P. T., Jiang A., Baker J. R., Belliveau J. W., Weisskoff R. M. and Rosen B. R. FMRI and PET demonstrate sustained blood oxygenation and flow enhancement during extended visual stimulation durations. 3rd Annual Meeting of the Society of Magnetic resonance. Abstr., p. 453 (1995).
4. Krüger G., Kleinschmidt A. and Frahm J. Dynamic MRI sensitized to cerebral blood oxygenation and flow during sustained activation of human visual cortex. Magn. Reson. Med. 35, 797-800 (1996).
5. Howseman A. M., Josephs O., Porter D., Müller E., Frackowiak R. S. J. and Turner R. Sustained activation in visual cortex using EPI and FLASH fMRI. Neuroimage 3, Abstr., S8 (1996).
6. Fransson P., Krüger G., Merboldt K. D. and Frahm J. A comparative FLASH and EPI study of repetitive and sustained visual activation. NMR Biomed. 10, 204-207 (1997).
7. Krüger G., Frahm J. and Kleinschmidt A. The cerebral blood oxygenation response to functional challenge: differences between motor and visual cortex. 4th Annual Meeting of the International Society of Magnetic Resonance in Medicine. Abstr., p. 1757 (1996).
8. Krüger G., Kleinschmidt A. and Frahm J. Stimulus-dependence of cerebral blood oxygenation changes during sustained activation of human visual cortex. Neuroimage 5, Abstr., S36 (1997).
9. Vafaee M., Meyer E., Marrett S., Paus T., Evans A. C. and Gjedde A. Frequency-dependent changes of cerebral metabolic rate of oxygen (CMRO2) in the human striate cortex. Neuroimage 5, Abstr., S35 (1997).
10. Bandettini P. A., Jesmanowicz A., Wong E. C. and Hyde J. S. Processing strategies for time-course data sets in functional MRI of the human brain. Magn. Reson. Med. 30, 161-173 (1993).
11. Kleinschmidt A., Requardt M., Merboldt K. D. and Frahm J. On the use of temporal correlation coefficients for magnetic resonance mapping of functional brain activation. Individualized thresholds and spatial response delineation. Intern. J. Imag. Sys. Technol 6, 238-244 (1995).
12. Obrig H., Heekeren H. R., Eberle K., Ramshorn A., Wenzel R., v. Pannwitz W., Villringer K., Schwiemann J., Kurth R. and Villringer A. Hemoglobin oxygenation changes during prolonged visual stimulation. Neuroimage 5, Abstr., S39 (1997).
13. Bandettini P. A., Kwong K. K., Davis T. L., Tootell R. B. H., Wong E. C., Fox P. T., Belliveau J. W., Weisskoff R. M. and Rosen B. R. Characterization of cerebral blood oxygenation and flow changes during prolonged brain activation. Human Brain Mapping 5, 93-109 (1997).
14. Kleinschmidt A., Gruber O., Posse S., Jäncke L., Grosse-Ruyken M., Müller-Gärtner H. W. and Freund H. J. Deriving stimulus-response functions from cerebral blood oxygenation - Optimizing timing and design of sensory activation paradigms. Neuroimage 5, Abstr., S38 (1997).
15. Buxton R. B., Wong E. C. and Frank L. R. A biomechanical interpretation of the BOLD signal time course: the balloon model. 5th Annual Meeting of the International Society of Magnetic Resonance in Medicine. Abstr., p. 743 (1997).
16. 1H NMR in human visual cortex during physiologic stimulation. Proc. Natl Acad. Sci. USA 88, 5829-5831 (1991).
17. Fox P. T., Raichle M. E., Mintun M. A. and Dence C. Nonoxidative glucose consumption during focal physiologic neural activity. Science, 241, 462-464 (1988).
18. Marrett S., Meyer E., Kuwabara H., Evans A. and Gjedde A. Differential increases of oxygen metabolism in visual cortex. J. Cereb. Blood Flow Metab. 15, Abstr., S80 (1995).