-
1
-
-
0020408957
-
Isolation and structure of bryostatin 1
-
Pettit, G. R., Herald, C. L., Doubek, D. L., Herald, D. L., Arnold, E., and Clardy, J. Isolation and structure of bryostatin 1. J. Am. Chem. Soc., 104: 6846-6948, 1982.
-
(1982)
J. Am. Chem. Soc.
, vol.104
, pp. 6846-6948
-
-
Pettit, G.R.1
Herald, C.L.2
Doubek, D.L.3
Herald, D.L.4
Arnold, E.5
Clardy, J.6
-
2
-
-
0023698185
-
Activation of human T lymphocytes by bryostatin 1
-
Hess, A. D., Silankis, M. K., Esa, A. H., Pettit, G. R., and May, W. S. Activation of human T lymphocytes by bryostatin 1. J. Immunol., 141: 3263-3269, 1988.
-
(1988)
J. Immunol.
, vol.141
, pp. 3263-3269
-
-
Hess, A.D.1
Silankis, M.K.2
Esa, A.H.3
Pettit, G.R.4
May, W.S.5
-
3
-
-
0026602830
-
Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines
-
Kennedy, M. J., Prestigiacomo, L. J., Tyler, G., May, W. S., and Davidson, N. E. Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines. Cancer Res., 52: 1278-1283, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1278-1283
-
-
Kennedy, M.J.1
Prestigiacomo, L.J.2
Tyler, G.3
May, W.S.4
Davidson, N.E.5
-
4
-
-
0024552224
-
Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cells
-
Dale, I. L., and Gescher, A. Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cells. Int. J. Cancer, 43: 158-163, 1989.
-
(1989)
Int. J. Cancer
, vol.43
, pp. 158-163
-
-
Dale, I.L.1
Gescher, A.2
-
5
-
-
0025961690
-
Successful treatment of murine melanoma with bryostatin 1
-
Schuchter, L. M., Esa, A. H., May, S., Laulis, M. K., Pettit, G. R., and Hess, A. D. Successful treatment of murine melanoma with bryostatin 1. Cancer Res., 51: 682-687, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 682-687
-
-
Schuchter, L.M.1
Esa, A.H.2
May, S.3
Laulis, M.K.4
Pettit, G.R.5
Hess, A.D.6
-
6
-
-
0026532012
-
Preclinical evaluation of bryostatin as an anticancer agent against several murine tumor cell lines: In vitro versus in vivo activity
-
Hornung, R. L., Pearson, J. W., Beckwith, M., and Longo, D. L. Preclinical evaluation of bryostatin as an anticancer agent against several murine tumor cell lines: in vitro versus in vivo activity. Cancer Res., 52: 101-107, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 101-107
-
-
Hornung, R.L.1
Pearson, J.W.2
Beckwith, M.3
Longo, D.L.4
-
7
-
-
0025264496
-
Bryostatin 1, a unique biologic response modifier: Antileukemic activity in vitro
-
Jones, R. J., Sharkis, S. J., Miller, C. B., Rowinsky, E. K., Burke, P. J., and May, W. S. Bryostatin 1, a unique biologic response modifier: antileukemic activity in vitro. Blood, 75: 1319-1323, 1990.
-
(1990)
Blood
, vol.75
, pp. 1319-1323
-
-
Jones, R.J.1
Sharkis, S.J.2
Miller, C.B.3
Rowinsky, E.K.4
Burke, P.J.5
May, W.S.6
-
8
-
-
0010050058
-
Antineoplastic bryostatins are multipotent stimulators of human hematopoietic progenitor cells
-
May, W. S., Sharkis, S. S., Esa, A. H., Gebbia, V., Kraft, A. S., Pettit, G. R., and Sensenbrenner, L. L. Antineoplastic bryostatins are multipotent stimulators of human hematopoietic progenitor cells. Proc. Natl. Acad. Sci. USA, 84: 8483-8487, 1987.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 8483-8487
-
-
May, W.S.1
Sharkis, S.S.2
Esa, A.H.3
Gebbia, V.4
Kraft, A.S.5
Pettit, G.R.6
Sensenbrenner, L.L.7
-
9
-
-
0025076580
-
The action of bryostatin 1 on normal human hematopoietic progenitors is mediated by accessory cell release of growth factors
-
Sharkis, S. J., Jones, R. J., Bellis, M. L., Demetri, G. D., Griffin, J. D., Civin, C., and May, W. S. The action of bryostatin 1 on normal human hematopoietic progenitors is mediated by accessory cell release of growth factors. Blood, 76: 716-721, 1990.
-
(1990)
Blood
, vol.76
, pp. 716-721
-
-
Sharkis, S.J.1
Jones, R.J.2
Bellis, M.L.3
Demetri, G.D.4
Griffin, J.D.5
Civin, C.6
May, W.S.7
-
10
-
-
0027489606
-
Phase I study of bryostatin 1 : Assessment of interleukin-6 and tumor necrosis factor α in vivo
-
Philip, P. A., Rea, D., Thavasu, P., Carmichael, J., Stuart, N. S., Rockett, H., Talbot, D. C., Ganesan, T., Pettit, G. R., Balkwill, F., and Harris, A. L. Phase I study of bryostatin 1 : assessment of interleukin-6 and tumor necrosis factor α in vivo. J. Natl. Cancer Inst., 85: 1812-1818, 1993.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 1812-1818
-
-
Philip, P.A.1
Rea, D.2
Thavasu, P.3
Carmichael, J.4
Stuart, N.S.5
Rockett, H.6
Talbot, D.C.7
Ganesan, T.8
Pettit, G.R.9
Balkwill, F.10
Harris, A.L.11
-
11
-
-
0027326957
-
A Phase I study of intravenous bryostatin 1 in patients with advanced cancer
-
Prendiville, J., Crowther, D., Thatcher, N., Woll, P. J., Fox, B. W., McGown, A., Testa, N., Stern, P., McDermott, R., Potter, M., and Pettit, G. R. A Phase I study of intravenous bryostatin 1 in patients with advanced cancer. Br. J. Cancer, 68: 418-424, 1993.
-
(1993)
Br. J. Cancer
, vol.68
, pp. 418-424
-
-
Prendiville, J.1
Crowther, D.2
Thatcher, N.3
Woll, P.J.4
Fox, B.W.5
McGown, A.6
Testa, N.7
Stern, P.8
McDermott, R.9
Potter, M.10
Pettit, G.R.11
-
12
-
-
0029084804
-
A Phase I trial of bryostatin 1 in patients with advanced malignancy using a 24-hour intravenous infusion
-
Jayson, G. C., Crowther, D., Prendiville, J., McGown, A. T., Scheid, C., Stern, P., Young, R., Brenchley, P., Chang, J., Owens, S., and Pettit, G. R. A Phase I trial of bryostatin 1 in patients with advanced malignancy using a 24-hour intravenous infusion. Br. J. Cancer, 72: 461-468, 1995.
-
(1995)
Br. J. Cancer
, vol.72
, pp. 461-468
-
-
Jayson, G.C.1
Crowther, D.2
Prendiville, J.3
McGown, A.T.4
Scheid, C.5
Stern, P.6
Young, R.7
Brenchley, P.8
Chang, J.9
Owens, S.10
Pettit, G.R.11
-
13
-
-
0027988081
-
Immunomodulation in patients receiving bryostatin 1 in a Phase I clinical study: Comparison with effects of bryostatin 1 on lymphocyte function in vitro
-
Scheid, C., Prendiville, J., Jayson, G., Crowther, D., Fox, B., Pettit, G. R., and Stern, P. L. Immunomodulation in patients receiving bryostatin 1 in a Phase I clinical study: comparison with effects of bryostatin 1 on lymphocyte function in vitro. Cancer Immunol. Immunother., 39: 223-230, 1994.
-
(1994)
Cancer Immunol. Immunother.
, vol.39
, pp. 223-230
-
-
Scheid, C.1
Prendiville, J.2
Jayson, G.3
Crowther, D.4
Fox, B.5
Pettit, G.R.6
Stern, P.L.7
-
14
-
-
0022410234
-
Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60
-
Berkow, R. L., and Kraft, A. S. Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60. Biochem. Biophys. Res. Commun., 131: 1109-1116, 1985.
-
(1985)
Biochem. Biophys. Res. Commun.
, vol.131
, pp. 1109-1116
-
-
Berkow, R.L.1
Kraft, A.S.2
-
15
-
-
0010543768
-
Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60
-
Kraft, A. S., Smith, J. B., and Berkow, R. L. Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60. Proc. Natl. Acad. Sci. USA, 83: 1334-1338, 1986.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 1334-1338
-
-
Kraft, A.S.1
Smith, J.B.2
Berkow, R.L.3
-
16
-
-
0023253596
-
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin
-
Lond.
-
Hennings, H., Blumberg, P. M., Pettit, G. R., Herald, C. L., Shores, R. A., and Yuspa, S. H. Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin. Carcinogenesis (Lond.), 8: 1343-1346, 1987.
-
(1987)
Carcinogenesis
, vol.8
, pp. 1343-1346
-
-
Hennings, H.1
Blumberg, P.M.2
Pettit, G.R.3
Herald, C.L.4
Shores, R.A.5
Yuspa, S.H.6
-
17
-
-
0026660771
-
Two protein kinase activators, bryostatin I and phorbol-12-myristate-13-acetate, have different effects on haemopoietic cell proliferation and differentiation
-
Ng, S. B., and Guy, G. R. Two protein kinase activators, bryostatin I and phorbol-12-myristate-13-acetate, have different effects on haemopoietic cell proliferation and differentiation. Cell Signalling, 4: 405-416, 1992.
-
(1992)
Cell Signalling
, vol.4
, pp. 405-416
-
-
Ng, S.B.1
Guy, G.R.2
-
18
-
-
0028055160
-
Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts
-
Szallasi, Z., Smith, C. B., Pettit, G. R., and Blumberg, P. M. Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts. J. Biol. Chem., 269: 2118-2124, 1994.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2118-2124
-
-
Szallasi, Z.1
Smith, C.B.2
Pettit, G.R.3
Blumberg, P.M.4
-
19
-
-
0026067787
-
II-protein kinase C to the nucleus of human promyelocytic (HL-60) leukemia cells
-
II-protein kinase C to the nucleus of human promyelocytic (HL-60) leukemia cells. J. Biol. Chem., 266: 28-33, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 28-33
-
-
Hocevar, B.A.1
Fields, A.P.2
-
20
-
-
0027322773
-
Inhibition of phorbol ester-induced T cell proliferation by bryostatin 1 is associated with rapid degradation of protein kinase C
-
Isakov, N., Galron, D., Mustelin, T., Pettit, G. R., and Altman, A. Inhibition of phorbol ester-induced T cell proliferation by bryostatin 1 is associated with rapid degradation of protein kinase C. J. Immunol., 150: 1195-1204, 1993.
-
(1993)
J. Immunol.
, vol.150
, pp. 1195-1204
-
-
Isakov, N.1
Galron, D.2
Mustelin, T.3
Pettit, G.R.4
Altman, A.5
-
21
-
-
0029812896
-
Ubiquitination of protein kinase C-α and degradation by the proteosome
-
Lee, H-W., Smith, L., Pettit, G. R., Vinitsky, A., and Smith, J. B. Ubiquitination of protein kinase C-α and degradation by the proteosome. J. Biol. Chem., 271: 20973-20976, 1996.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20973-20976
-
-
Lee, H.-W.1
Smith, L.2
Pettit, G.R.3
Vinitsky, A.4
Smith, J.B.5
-
22
-
-
0021288161
-
2+-sensitive, phospholipid-dependent kinase activity in phorbol ester-treated 3T3 cells
-
2+-sensitive, phospholipid-dependent kinase activity in phorbol ester-treated 3T3 cells. Biochem. Biophys. Res. Commun., 120: 1053-1059, 1984.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.120
, pp. 1053-1059
-
-
Rodriguez-Pena, R.1
Rozengurt, E.2
-
23
-
-
0026481364
-
Potentiation of the activity of 1-β-D-arabinofuranosylcytosine by the macrocyclic lactone PKC activator bryostatin 1 in HL-60 cells: Association with enhanced fragmentation of mature DNA
-
Grant, S., Jarvis, D., Swerdlow, P., Turner, A., Traylor, R., Wallace, H., Lin, P-S., Pettit, G. R., and Gewirtz, D. A. Potentiation of the activity of 1-β-D-arabinofuranosylcytosine by the macrocyclic lactone PKC activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA. Cancer Res., 52: 6270-6278, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 6270-6278
-
-
Grant, S.1
Jarvis, D.2
Swerdlow, P.3
Turner, A.4
Traylor, R.5
Wallace, H.6
Lin, P.-S.7
Pettit, G.R.8
Gewirtz, D.A.9
-
24
-
-
0028181584
-
Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-β-D-arabinofuranosylcytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells
-
Jarvis, W. D., Gewirtz, D. A., Povirk, L., Turner, A., Traylor, R., Pettit, G. R., and Grant, S. Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-β-D-arabinofuranosylcytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells. Biochem. Pharmacol., 47: 839-852, 1994.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 839-852
-
-
Jarvis, W.D.1
Gewirtz, D.A.2
Povirk, L.3
Turner, A.4
Traylor, R.5
Pettit, G.R.6
Grant, S.7
-
25
-
-
0026049659
-
Rescue from programmed cell death in leukemia and normal myeloid cells
-
Lotem, J., Cragoe, E. J., and Sachs, L. Rescue from programmed cell death in leukemia and normal myeloid cells. Blood, 78: 953-960, 1991.
-
(1991)
Blood
, vol.78
, pp. 953-960
-
-
Lotem, J.1
Cragoe, E.J.2
Sachs, L.3
-
26
-
-
0024402595
-
Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C
-
McConkey, D. J., Hartzell, P., Jondal, M., and Orrenius, S. Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C. J. Biol. Chem., 264: 13399-13402, 1989.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13399-13402
-
-
McConkey, D.J.1
Hartzell, P.2
Jondal, M.3
Orrenius, S.4
-
27
-
-
0028360309
-
Induction of a common pathway of apoptosis by staurosporine
-
Bertrand, R., Solary, E., O'Connor, P., Kohn, K. W., and Pommier, Y. Induction of a common pathway of apoptosis by staurosporine. Exp. Cell Res., 211: 314-321, 1994.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 314-321
-
-
Bertrand, R.1
Solary, E.2
O'Connor, P.3
Kohn, K.W.4
Pommier, Y.5
-
28
-
-
0028170263
-
Modulation of 1-β-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C
-
Grant, S., Turner, A., Bartimole, T. M., Nelms, P. A., Joe, V. C., and Jarvis, W. D. Modulation of 1-β-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C. Oncol. Res., 6: 87-99, 1994.
-
(1994)
Oncol. Res.
, vol.6
, pp. 87-99
-
-
Grant, S.1
Turner, A.2
Bartimole, T.M.3
Nelms, P.A.4
Joe, V.C.5
Jarvis, W.D.6
-
29
-
-
0024470862
-
Induction of endonucleolytic DNA cleavage by in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer agents: A cautionary note
-
Kauffman, S. H. Induction of endonucleolytic DNA cleavage by in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer agents: a cautionary note. Cancer Res., 49: 5870-5878, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 5870-5878
-
-
Kauffman, S.H.1
-
30
-
-
0027205172
-
Induction of DNA strand breaks associated with apoptosis during treatment of leukemias
-
Baltimore
-
Gorczyca, W., Bigman, K., Mittelman, A., Ahmed, T., Gong, J., Melamed, M. R., and Darzynkiewicz, Z. Induction of DNA strand breaks associated with apoptosis during treatment of leukemias. Leukemia (Baltimore), 7: 659-670, 1993.
-
(1993)
Leukemia
, vol.7
, pp. 659-670
-
-
Gorczyca, W.1
Bigman, K.2
Mittelman, A.3
Ahmed, T.4
Gong, J.5
Melamed, M.R.6
Darzynkiewicz, Z.7
-
31
-
-
0342748172
-
Bryostatin 1 induces long-term depletion of protein kinase C in vivo following a single intravenous injection
-
Bear, H. D., McFadden, A., Turner, A. J., and Grant, S. Bryostatin 1 induces long-term depletion of protein kinase C in vivo following a single intravenous injection. Anticancer Res., 6: 384-391, 1995.
-
(1995)
Anticancer Res.
, vol.6
, pp. 384-391
-
-
Bear, H.D.1
McFadden, A.2
Turner, A.J.3
Grant, S.4
-
32
-
-
0014385564
-
Isolation of mononuclear cells and granulocytes from human blood
-
Boyum, A. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest., 21: 77-84, 1968.
-
(1968)
Scand. J. Clin. Lab. Invest.
, vol.21
, pp. 77-84
-
-
Boyum, A.1
-
33
-
-
0030579076
-
Modulation of protein kinase C activity and calcium-sensitive isoform expression in human myeloid leukemia cells by bryostatin 1: Relationship to differentiation and ara-C-induced apoptosis
-
Grant, S., Turner, A. J., Freemerman, A. J., Wang, Z., Kramer, L., and Jarvis, W. D. Modulation of protein kinase C activity and calcium-sensitive isoform expression in human myeloid leukemia cells by bryostatin 1: relationship to differentiation and ara-C-induced apoptosis. Exp. Cell Res., 228: 65-75, 1996.
-
(1996)
Exp. Cell Res.
, vol.228
, pp. 65-75
-
-
Grant, S.1
Turner, A.J.2
Freemerman, A.J.3
Wang, Z.4
Kramer, L.5
Jarvis, W.D.6
-
34
-
-
0029039809
-
A sensitive platelet activation-based functional assay for the antileukemic agent bryostatin 1
-
Carr, M. E., Jr., Carr, S. L., and Grant, S. A sensitive platelet activation-based functional assay for the antileukemic agent bryostatin 1. Anticancer Drugs, 6: 384-391, 1995.
-
(1995)
Anticancer Drugs
, vol.6
, pp. 384-391
-
-
Carr Jr., M.E.1
Carr, S.L.2
Grant, S.3
-
35
-
-
0023903442
-
Phenotype of tumor-specific cytotoxic T-lymphocytes and requirements for their in vitro generation from tumor-bearing host and immune spleens
-
Bear, H. D., Susskind, B. M., Close, K. A., and Barrett, S. K. Phenotype of tumor-specific cytotoxic T-lymphocytes and requirements for their in vitro generation from tumor-bearing host and immune spleens. Cancer Res., 48: 1422-1427, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 1422-1427
-
-
Bear, H.D.1
Susskind, B.M.2
Close, K.A.3
Barrett, S.K.4
-
36
-
-
0025883791
-
+ cytotoxic T lymphocytes via CD3-ε differs from triggering via α/β T cell receptor: CD3-ε-induced cytotoxicity occurs in the absence of protein kinase C and does not result in exocytosis of serine esterases
-
+ cytotoxic T lymphocytes via CD3-ε differs from triggering via α/β T cell receptor: CD3-ε-induced cytotoxicity occurs in the absence of protein kinase C and does not result in exocytosis of serine esterases. J. Immunol., 147: 1115-1120, 1991.
-
(1991)
J. Immunol.
, vol.147
, pp. 1115-1120
-
-
Hengel, H.1
Wagner, H.2
Heeg, K.3
-
37
-
-
0025193495
-
Feε RII/CD23. The low affinity receptor for for IgE
-
Conrad, D. H. Feε RII/CD23. The low affinity receptor for for IgE. Annu. Rev. Immunol., 8: 623-645, 1990.
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 623-645
-
-
Conrad, D.H.1
-
38
-
-
0343182793
-
Effect of a combined exposure to 1-β-D-arabinofuranosylcytosine, bryostatin 1, and rGM-CSF on the in vitro clonogenic growth of normal and leukemic human hematopoietic progenitor cells
-
Baltimore
-
Grant, S., Traylor, R., Bhalla, K., McCrady, C., and Pettit, G. R. Effect of a combined exposure to 1-β-D-arabinofuranosylcytosine, bryostatin 1, and rGM-CSF on the in vitro clonogenic growth of normal and leukemic human hematopoietic progenitor cells. Leukemia (Baltimore), 5: 432-439, 1993.
-
(1993)
Leukemia
, vol.5
, pp. 432-439
-
-
Grant, S.1
Traylor, R.2
Bhalla, K.3
McCrady, C.4
Pettit, G.R.5
-
39
-
-
0028089047
-
Successful treatment of human Waldenstrom's macroglobulinemia with combination biological and chemotherapy agents
-
Mohammad, R. M., Al-Katib, A., Pettit, G. R., and Sensenbrenner, L. L. Successful treatment of human Waldenstrom's macroglobulinemia with combination biological and chemotherapy agents. Cancer Res., 54: 165-168, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 165-168
-
-
Mohammad, R.M.1
Al-Katib, A.2
Pettit, G.R.3
Sensenbrenner, L.L.4
-
40
-
-
0029892167
-
The bryostatins inhibit growth of B16/F10 melanoma cells in vitro though a protein kinase C-independent mechanism: Dissociation of activities using 26-epi-bryostatin 1
-
Szallasi, Z., Du, L., Levine, R., Lewin, N. E., Nguyen, P. N., Williams, M. D., Pettit, G. R., and Blumberg, P. M. The bryostatins inhibit growth of B16/F10 melanoma cells in vitro though a protein kinase C-independent mechanism: dissociation of activities using 26-epi-bryostatin 1. Cancer Res., 56: 2105-2111, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 2105-2111
-
-
Szallasi, Z.1
Du, L.2
Levine, R.3
Lewin, N.E.4
Nguyen, P.N.5
Williams, M.D.6
Pettit, G.R.7
Blumberg, P.M.8
-
41
-
-
0012623854
-
Phase I trial of bryostatin 1 in relapsed lymphoma and CLL
-
Varterasian, M., Eilender, D., Mohammad, R., Chen, B., Hulburd, K., Rodriguez, D., Pluda, J., Valdivieso, M., and Al-Katib, A. Phase I trial of bryostatin 1 in relapsed lymphoma and CLL. Proc. Am. Soc. Clin. Oncol., 15: 481, 1996.
-
(1996)
Proc. Am. Soc. Clin. Oncol.
, vol.15
, pp. 481
-
-
Varterasian, M.1
Eilender, D.2
Mohammad, R.3
Chen, B.4
Hulburd, K.5
Rodriguez, D.6
Pluda, J.7
Valdivieso, M.8
Al-Katib, A.9
-
42
-
-
0030448021
-
Functions of ceramide in coordinating cellular responses to stress
-
Washington DC
-
Hannun, Y. A. Functions of ceramide in coordinating cellular responses to stress. Science (Washington DC), 274: 1855-1859, 1996.
-
(1996)
Science
, vol.274
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
43
-
-
0029948396
-
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
-
Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P. G., Coso, O. A., Gutkind, J. S., and Spiegel, S. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature (Lond.), 381: 800-803, 1996.
-
(1996)
Nature (Lond.)
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Pirianov, G.2
Kleuser, B.3
Vanek, P.G.4
Coso, O.A.5
Gutkind, J.S.6
Spiegel, S.7
-
44
-
-
0030471559
-
Modulation of drug-induced apoptosis by interruption of the protein kinase C signal transduction pathway: A new therapeutic strategy
-
Grant, S., and Jarvis, W. D. Modulation of drug-induced apoptosis by interruption of the protein kinase C signal transduction pathway: a new therapeutic strategy. Clin. Cancer Res., 2: 1915-1920, 1996.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1915-1920
-
-
Grant, S.1
Jarvis, W.D.2
-
45
-
-
0027315073
-
In vivo administration of the anticancer agent bryostatin 1 activates platelets and neutrophils and modulates protein kinase C activity
-
Berkow, R. L., Schlabach, L., Dodson, R., Benjamin, W. H., Jr., Pettit, G. R., Rustagi, P., and Kraft, A. S. In vivo administration of the anticancer agent bryostatin 1 activates platelets and neutrophils and modulates protein kinase C activity. Cancer Res., 53: 2810-2815. 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 2810-2815
-
-
Berkow, R.L.1
Schlabach, L.2
Dodson, R.3
Benjamin Jr., W.H.4
Pettit, G.R.5
Rustagi, P.6
Kraft, A.S.7
-
46
-
-
0030063389
-
Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C
-
Zhang, X., Zhang, R., Zhao, H., Cai, H., Gush, K. A., Kerr, R. G., Pettit, G. R., and Kraft, A. S. Preclinical pharmacology of the natural product anticancer agent bryostatin 1, an activator of protein kinase C. Cancer Res., 56: 802-808, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 802-808
-
-
Zhang, X.1
Zhang, R.2
Zhao, H.3
Cai, H.4
Gush, K.A.5
Kerr, R.G.6
Pettit, G.R.7
Kraft, A.S.8
-
47
-
-
0026645396
-
In vivo administration of bryostatin 1, a protein kinase C activator, decreases murine resistance to Salmonella typhimurium
-
Kraft, A. S., Adler, V., Hall, P., Pettit, G. R., Benjamin, W. H., and Briles, D. E. In vivo administration of bryostatin 1, a protein kinase C activator, decreases murine resistance to Salmonella typhimurium. Cancer Res., 52: 2143-2147, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 2143-2147
-
-
Kraft, A.S.1
Adler, V.2
Hall, P.3
Pettit, G.R.4
Benjamin, W.H.5
Briles, D.E.6
|