메뉴 건너뛰기




Volumn 128, Issue 4, 1998, Pages 733-739

In vivo glucose contribution to glutamate synthesis is maintained while its contribution to acetyl CoA is lowered in adult mice fed a diet with a high fat:carbohydrate ratio

Author keywords

Acetyl CoA synthesis; Dietary glucose metabolism; Glutamate synthesis; Mice; Stable isotopes

Indexed keywords

ACETYL COENZYME A; ALANINE; AMINO ACID; CARBOHYDRATE; CARBON 13; GLUCOSE; GLUTAMIC ACID;

EID: 0031953833     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/128.4.733     Document Type: Article
Times cited : (6)

References (25)
  • 1
    • 0022352027 scopus 로고
    • Regulation of flux through pyruvate dehydrogenase and pyruvate carboxylase in rat hepatocytes. Effects of fatty acids and glucagon
    • Agius, L. & Alberti, K. G. (1985) Regulation of flux through pyruvate dehydrogenase and pyruvate carboxylase in rat hepatocytes. Effects of fatty acids and glucagon. Eur. J. Biochem. 152: 699-707.
    • (1985) Eur. J. Biochem. , vol.152 , pp. 699-707
    • Agius, L.1    Alberti, K.G.2
  • 2
    • 0028831328 scopus 로고
    • Oxidation of glutamic acid by the splanchnic bed in humans
    • Battezzati, A., Brillon, D. J. & Matthews, D. E. (1995) Oxidation of glutamic acid by the splanchnic bed in humans. Am. J. Physiol. 269: E269-E276.
    • (1995) Am. J. Physiol. , vol.269
    • Battezzati, A.1    Brillon, D.J.2    Matthews, D.E.3
  • 3
    • 0028948918 scopus 로고
    • Isotopic evidence for the differential regulation of arginine and praline synthesis in man
    • Berthold, H. K., Reeds, P. J. & Klein, P. D. (1995) Isotopic evidence for the differential regulation of arginine and praline synthesis in man. Metabolism 44: 466-473.
    • (1995) Metabolism , vol.44 , pp. 466-473
    • Berthold, H.K.1    Reeds, P.J.2    Klein, P.D.3
  • 4
    • 0000837057 scopus 로고
    • Least squares analysis and simplification of multi-isotope mass spectra
    • Brauman, J. I. (1966) Least squares analysis and simplification of multi-isotope mass spectra. Anal. Chem. 38: 607-610.
    • (1966) Anal. Chem. , vol.38 , pp. 607-610
    • Brauman, J.I.1
  • 5
    • 0024409822 scopus 로고
    • Physiologic importance of glutamine
    • Bulus, N., Cerosimo, E., Ghishan, F. & Abumrad, N. (1989) Physiologic importance of glutamine. Metabolism 38 (suppl. 1): 1-5.
    • (1989) Metabolism , vol.38 , Issue.1 SUPPL. , pp. 1-5
    • Bulus, N.1    Cerosimo, E.2    Ghishan, F.3    Abumrad, N.4
  • 6
    • 0017865631 scopus 로고
    • The metabolic fates of amino acids and the formation of glutamine in skeletal muscle
    • Ghang, T. S. & Goldberg, A. L. (1978) The metabolic fates of amino acids and the formation of glutamine in skeletal muscle. J. Biol. Chem. 253: 3685-3696.
    • (1978) J. Biol. Chem. , vol.253 , pp. 3685-3696
    • Ghang, T.S.1    Goldberg, A.L.2
  • 8
    • 0028154225 scopus 로고
    • Growth and metabolism of gastrointestinal and skeletal muscle tissues in protein malnourished neonatal pigs
    • Ebner, S., Schoknecht, P., Reeds, P. J. & Burrin, D. G. (1994) Growth and metabolism of gastrointestinal and skeletal muscle tissues in protein malnourished neonatal pigs. Am. J. Physiol. 266: R1736-R1743.
    • (1994) Am. J. Physiol. , vol.266
    • Ebner, S.1    Schoknecht, P.2    Reeds, P.J.3    Burrin, D.G.4
  • 9
    • 0028901694 scopus 로고
    • 13C mass isotopomer distribution analysis of intermediates
    • 13C mass isotopomer distribution analysis of intermediates. J. Biol. Chem. 270: 10037-10042.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10037-10042
    • Fernandez, C.A.1    Des Rosiers, C.2
  • 10
    • 0027292150 scopus 로고
    • Dietary fat, carbohydrate balance, and weight maintenance
    • Flatt, J. P. (1993) Dietary fat, carbohydrate balance, and weight maintenance. Ann. N. Y. Acad. Sci. 683: 122-140.
    • (1993) Ann. N. Y. Acad. Sci. , vol.683 , pp. 122-140
    • Flatt, J.P.1
  • 11
    • 0029159657 scopus 로고
    • Quantification of carbohydrate oxidation by respiratory gas exchange and isotopic tracers
    • Glamour, T. S., McCullough, A. J., Sauer, P.J.J. & Kalhan, S. C. (1995) Quantification of carbohydrate oxidation by respiratory gas exchange and isotopic tracers. Am. J. Physiol. 268: E789-E796.
    • (1995) Am. J. Physiol. , vol.268
    • Glamour, T.S.1    McCullough, A.J.2    Sauer, P.J.J.3    Kalhan, S.C.4
  • 12
    • 0027997162 scopus 로고
    • Measurement of plasma protein synthesis rate in the infant pig: An investigation of alternative tracer approaches
    • Jahoor, F., Burrin, D. G., Reeds, P. J. & Frazer, M. (1994) Measurement of plasma protein synthesis rate in the infant pig: an investigation of alternative tracer approaches. Am. J. Physiol. 267: R221-R227.
    • (1994) Am. J. Physiol. , vol.267
    • Jahoor, F.1    Burrin, D.G.2    Reeds, P.J.3    Frazer, M.4
  • 13
    • 0031032537 scopus 로고    scopus 로고
    • Glucose production and gluconeogenesis are negatively related to body weight in mechanically ventilated, very low birth weight neonates
    • Keshen, T., Miller, R., Jahoor, F., Jaksic, T. & Reeds, P. (1997) Glucose production and gluconeogenesis are negatively related to body weight in mechanically ventilated, very low birth weight neonates. Pediatr. Res. 41: 132-138.
    • (1997) Pediatr. Res. , vol.41 , pp. 132-138
    • Keshen, T.1    Miller, R.2    Jahoor, F.3    Jaksic, T.4    Reeds, P.5
  • 14
    • 0025475371 scopus 로고
    • Is glutamine a conditionally essential amino acid?
    • Lacey, J. M. & Wilmore, D. W. (1990) Is glutamine a conditionally essential amino acid? Nutr. Rev. 48: 297-309.
    • (1990) Nutr. Rev. , vol.48 , pp. 297-309
    • Lacey, J.M.1    Wilmore, D.W.2
  • 17
    • 0027223159 scopus 로고
    • Splanchnic bed utilization of glutamine and glutamic acid in humans
    • Matthews, D. E., Marano, M. A. & Campbell, R. G. (1993) Splanchnic bed utilization of glutamine and glutamic acid in humans. Am. J. Physiol. 264: E848-E854.
    • (1993) Am. J. Physiol. , vol.264
    • Matthews, D.E.1    Marano, M.A.2    Campbell, R.G.3
  • 18
    • 0030861629 scopus 로고    scopus 로고
    • Dietary glucose is extensively recycled in the splanchnic bed of fed adult mice
    • Pascual, M., Jahoor, F., Reeds, P. J. (1997) Dietary glucose is extensively recycled in the splanchnic bed of fed adult mice. J. Nutr. 127: 1480-1489.
    • (1997) J. Nutr. , vol.127 , pp. 1480-1489
    • Pascual, M.1    Jahoor, F.2    Reeds, P.J.3
  • 20
    • 0029883954 scopus 로고    scopus 로고
    • Enteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs
    • Reeds, P. J., Burrin, D. G., Jahoor, F., Wykes, L., Henry, J. & Frazer, E. M. (1996) Enteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs. Am. J. Physiol. 270: E413-E418.
    • (1996) Am. J. Physiol. , vol.270
    • Reeds, P.J.1    Burrin, D.G.2    Jahoor, F.3    Wykes, L.4    Henry, J.5    Frazer, E.M.6
  • 21
    • 0029999869 scopus 로고    scopus 로고
    • Regulation of hepatic pyruvate dehydrogenase kinase by insulin and dietary manipulation in vivo. Studies with the euglycaemic-hyperinsulinaemic clamp
    • Sugden, M. C., Fryer, L. G. & Holness, M. J. (1996) Regulation of hepatic pyruvate dehydrogenase kinase by insulin and dietary manipulation in vivo. Studies with the euglycaemic-hyperinsulinaemic clamp. Biochim. Biophys. Acta 1316: 114-120.
    • (1996) Biochim. Biophys. Acta , vol.1316 , pp. 114-120
    • Sugden, M.C.1    Fryer, L.G.2    Holness, M.J.3
  • 22
    • 0031967119 scopus 로고    scopus 로고
    • Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk-replacer fed piglets
    • Stoll, B., Henry, J., Reeds, P. J., Yu, H., Jahoor, F. & Burrin, D. G. (1997) Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk-replacer fed piglets J. Nutr. 128: 606-614.
    • (1997) J. Nutr. , vol.128 , pp. 606-614
    • Stoll, B.1    Henry, J.2    Reeds, P.J.3    Yu, H.4    Jahoor, F.5    Burrin, D.G.6
  • 23
    • 0028358197 scopus 로고
    • Glutamine metabolism in rat small intestine: Synthesis of three-carbon products in isolated enterocytes
    • Watford, M. (1994) Glutamine metabolism in rat small intestine: synthesis of three-carbon products in isolated enterocytes. Biochim. Biophys. Acta 1200: 73-78.
    • (1994) Biochim. Biophys. Acta , vol.1200 , pp. 73-78
    • Watford, M.1
  • 24
    • 0016830873 scopus 로고
    • Intestinal metabolism of glutamine and glutamate from the lumen as compared to glutamine from blood
    • Windmueller, H. G. & Spaeth, A. E. (1975) Intestinal metabolism of glutamine and glutamate from the lumen as compared to glutamine from blood. Arch. Biochem. Biophys. 171: 662-672.
    • (1975) Arch. Biochem. Biophys. , vol.171 , pp. 662-672
    • Windmueller, H.G.1    Spaeth, A.E.2
  • 25
    • 0018898289 scopus 로고
    • Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats
    • Windmueller, H. G. & Spaeth, A. E. (1980) Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats. J. Biol. Chem. 22: 107-112.
    • (1980) J. Biol. Chem. , vol.22 , pp. 107-112
    • Windmueller, H.G.1    Spaeth, A.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.