A case of cicatricial pemphigoid with simultaneous IgG autoantibodies against the 180 kd bullous pemphigoid antigen and laminin 5

Journal of the American Academy of Dermatology

Volumn 38, Issue 4, 1998, Pages 624-627

  Kawahara, Y ^a   Amagai, M ^a   Ohata, Y ^a   Ishii, K ^a   Hasegawa, Y ^a   Hsu, R ^a   Yee, C ^a   Yancey, K B ^a   Nishikawa, T ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; IMMUNOGLOBULIN G;

AGED; ANTIBODY DETECTION; ARTICLE; AUTOIMMUNE DISEASE; CASE REPORT; HUMAN; MALE; MUCOUS MEMBRANE PEMPHIGOID; PENIS GLANS; PRIORITY JOURNAL; SKIN BIOPSY; SYMBLEPHARON;

EID: 0031953372     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0190-9622(98)70129-X     Document Type: Article

References (20)

1. P Bernard C Prost N Durepaire N Basset-Seguin L Didierjean J-H. Saurat The major cicatricial pemphigoid antigen is a 180-kd protein that shows immunologic cross-reactivities with the bullous pemphigoid antigens J Invest Dermatol 99 1992 174 179
2. SD Balding C Prost LA Diaz P Bernard C Bedane D Aberdam Cicatricial pemphigoid autoantibodies react with multiple sites on the BP180 extracellular domain J Invest Dermatol 106 1996 141 146
3. N Domologe-Hultsch WR Gammon RA Briggaman SG Gil WG Carter KB. Yancey Epiligrin, the major human keratinocyte integrin ligand, is a target in both an acquired autoimmune and an inherited subepidermal blistering skin disease J Clin Invest 90 1992 1628 1633
4. T Hashimoto H Murakami Y Senboshi H Kanzaki J Arata KB Yancey Antiepiligrin cicatricial pemphigoid: the first case report from Japan J Am Acad Dermatol 34 1996 940 942
5. LS Chan AA Majmudar HH Tran F Meier G Schaumburg-Lever M Chen Laminin-6 and laminin-5 are recognized by autoantibodies in a subset of cicatricial pemphigoid J Invest Dermatol 108 1997 848 853
6. Z Lazarova R Hsu C Yee KB. Yancey IgG autoantibodies in patients with antiepiligrin cicatricial pemphigoid recognize the alpha subunits of laminins 5 and 6 [abstract] J Invest Dermatol 108 1997 592a
7. Yancey KB. Cicatricial pemphigoid. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, et al., editors. Dermatology in general medicine. 5th ed. New York: McGraw-Hill. In press.
8. EP Smith TB Taylor LJ Meyer JJ. Zone Identification of a basement membrane zone antigen reactive with circulating IgA antibody in ocular cicatricial pemphigoid J Invest Dermatol 101 1993 619 623
9. RF Ghohestani JF Nicolas P Rousselle AL. Claudy Identification of a 168-kd mucosal antigen in a subset of patients with cicatricial pemphigoid J Invest Dermatol 107 1996 136 139
10. K Matsumura T Hashimoto M Amagai T. Nishikawa The majority of bullous pemphigoid and herpes gestationis serum samples react with NC16a domain of the 180 kd bullous pemphigoid antigen Arch Dermatol Res 288 1996 507 509
11. Y Kawahara K Matsumura T Hashimoto T. Nishikawa Immunoblot analysis of autoantigens in localized pemphigoid and pemphigoid nodularis Acta Derm Venereol (Stockh) 77 1997 187 190
12. T Masunaga H Shimizu C Yee L Borradori Z Lazarova T Nishikawa The extracellular domain of BPAG2 localizes to anchoring filaments and its carboxyl terminus extends to the lamina densa of normal human epidermal basement membrane J Invest Dermatol 109 1997 200 206
13. Z Lazarova C Yee T Darling RA Briggaman KB. Yancey Passive transfer of antilaminin 5 antibodies induces subepidermal blisters in neonatal mice J Clin Invest 98 1996 1509 1518
14. G Kirtschig MP Marinkovich RA Burgeson KB. Yancey Antibasement–membrane autoantibodies in patients with antiepiligrin cicatricial pemphigoid bind the a subunit of laminin 5 J Invest Dermatol 105 1995 543 548
15. GJ Giudice DJ Emery LA. Diaz Cloning and primary structural analysis of the bullous pemphigoid autoantigen, BP180 J Invest Dermatol 99 1992 243 250
16. GJ Giudice DJ Emery BD Zelickson GJ Anhalt Z Liu LA. Diaz Bullous pemphigoid and herpes gestationis autoantibodies recognize a common noncollagenous site on the BP180 ectodomain J Immunol 151 1993 5742 5750
17. C Bedane JR McMillan SD Balding P Bernard C Prost J-M Bonnetblanc Bullous pemphigoid and cicatricial pemphigoid autoantibodies react with ultrastructurally separable epitopes on the BP180 ectodomain: evidence that BP180 spans the lamina lucida J Invest Dermatol 108 1997 901 907
18. WG Carter MC Ryan PJ. Gahr Epiligrin, a new cell adhesion ligand for integrin a3b1 in epithelial basement membranes Cell 65 1991 599 610
19. T Masunaga H Shimizu A Ishiko T Tomita D Aberdam J-P Ortonne Localization of laminin 5 in the epidermal basement membrane J Histochem Cytochem 44 1996 1223 1230
20. JA McGrath B Gatalica AM Christiano K Li K Owaribe JR McMillan Mutations in the 180-kd bullous pemphigoid antigen (BPAG2), a transmembrane hemidesmosomal collagen (COL17A1), in generalized atrophic benign epidermolysis bullosa Nature Genet 11 1995 83 86