-
1
-
-
0028983198
-
Prognostic value of cathepsin-D expression in female breast cancer
-
Aaltonen M, Lipponen P, Kosma M, Aaltomaa S, Syrjanen K. 1995. Prognostic value of cathepsin-D expression in female breast cancer. Anticancer Res 15: 1033-1038.
-
(1995)
Anticancer Res
, vol.15
, pp. 1033-1038
-
-
Aaltonen, M.1
Lipponen, P.2
Kosma, M.3
Aaltomaa, S.4
Syrjanen, K.5
-
2
-
-
0029094486
-
Comparisons of the three-dimensional structures, specificities and glycosylation of renin, yeast proteinase a and cathepsin D
-
Takuhashi K, ed. New York: Plenum Press
-
Aguilar CF, Dhanaraj V, Guruprasad K, Dealwis C, Badasso M, Cooper JB, Wood SP, Blundell TL. 1995. Comparisons of the three-dimensional structures, specificities and glycosylation of renin, yeast proteinase A and cathepsin D. In: Takuhashi K, ed. Aspanic proteinases: Structure, function, biology, and biomedical implications 362. New York: Plenum Press, pp 155-166.
-
(1995)
Aspanic Proteinases: Structure, Function, Biology, and Biomedical Implications
, vol.362
, pp. 155-166
-
-
Aguilar, C.F.1
Dhanaraj, V.2
Guruprasad, K.3
Dealwis, C.4
Badasso, M.5
Cooper, J.B.6
Wood, S.P.7
Blundell, T.L.8
-
3
-
-
0027518526
-
X-ray crystallographic studies of complexes of pepstatin a and a Statine containing human renin inhibitor with endothiapepsin
-
Bailey D, Cooper JB, Veerapandian B, Blundell TL, Atrash B, Jones DM, Szelke M. 1993. X-ray crystallographic studies of complexes of pepstatin A and a Statine containing human renin inhibitor with endothiapepsin. Biochemical J 259:363-71.
-
(1993)
Biochemical J
, vol.259
, pp. 363-371
-
-
Bailey, D.1
Cooper, J.B.2
Veerapandian, B.3
Blundell, T.L.4
Atrash, B.5
Jones, D.M.6
Szelke, M.7
-
4
-
-
0027165319
-
Crystal structures of native and inhibited forms of human cathepsin D: Implications for lysosomal targeting and drug design
-
Baldwin ET, Bhat TN, Gulnik S, Hosur MV, Sowder RC, Cachau RE, Collins J, Silva AM. Erickson JW. 1993. Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design. Proc Natl Acad Sci 90:6769-6800.
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 6769-6800
-
-
Baldwin, E.T.1
Bhat, T.N.2
Gulnik, S.3
Hosur, M.V.4
Sowder, R.C.5
Cachau, R.E.6
Collins, J.7
Silva, A.M.8
Erickson, J.W.9
-
5
-
-
0001310293
-
Cathepsin D and other carboxyl proteinases
-
Amsterdam: Elsevier
-
Barrett AJ. 1977. Cathepsin D and other carboxyl proteinases. In: Proteinases of mammalian cells and tissues. Amsterdam: Elsevier. pp 209-248.
-
(1977)
Proteinases of Mammalian Cells and Tissues
, pp. 209-248
-
-
Barrett, A.J.1
-
6
-
-
0029953972
-
Self activation of recombinant human cathepsin D at a newly engineered cleavage junction: "Short" pseudocathepsin D
-
Beyer BM, Dunn BM. 1996. Self activation of recombinant human cathepsin D at a newly engineered cleavage junction: "Short" pseudocathepsin D. J Biol Chem 277:15590-15596.
-
(1996)
J Biol Chem
, vol.277
, pp. 15590-15596
-
-
Beyer, B.M.1
Dunn, B.M.2
-
7
-
-
0026608412
-
Isolation and characterization of a stable activation intermediate of the lysosomal aspartyl protease cathepsin D
-
Conner GE, Richo G. 1992. Isolation and characterization of a stable activation intermediate of the lysosomal aspartyl protease cathepsin D. Biochemistry 31:1142-1147.
-
(1992)
Biochemistry
, vol.31
, pp. 1142-1147
-
-
Conner, G.E.1
Richo, G.2
-
8
-
-
0028278857
-
X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen
-
Dealwis CG, Frazao C, Badasso M, Cooper JP, Tickle IJ, Driessen H, Blundell TL, Murakami K, Miyazaki H, Sueiras-Diaz J. 1994. X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen. J Mol Biol 256:342-360.
-
(1994)
J Mol Biol
, vol.256
, pp. 342-360
-
-
Dealwis, C.G.1
Frazao, C.2
Badasso, M.3
Cooper, J.P.4
Tickle, I.J.5
Driessen, H.6
Blundell, T.L.7
Murakami, K.8
Miyazaki, H.9
Sueiras-Diaz, J.10
-
9
-
-
0023943263
-
Cathepsin D is membrane-associated in macrophage endosomes
-
Diment S, Leech M, Stahl P. 1988. Cathepsin D is membrane-associated in macrophage endosomes. J Biol Chem 265:6901-6908.
-
(1988)
J Biol Chem
, vol.265
, pp. 6901-6908
-
-
Diment, S.1
Leech, M.2
Stahl, P.3
-
10
-
-
0028695485
-
Analysis of proteinase specificity by studies of peptide substrates: The use of UV and fluorescence spectroscopy to quantitate rates of enzymatic cleavage
-
Pennington M. Dunn BM, eds. Totowa, New Jersey: Humana Press Inc.
-
Dunn BM, Scarborough PE, Davenport R, Swietnicki W. 1994. Analysis of proteinase specificity by studies of peptide substrates: The use of UV and fluorescence spectroscopy to quantitate rates of enzymatic cleavage. In: Pennington M. Dunn BM, eds. Peptide analysis protocols. Totowa, New Jersey: Humana Press Inc. pp 225-243.
-
(1994)
Peptide Analysis Protocols
, pp. 225-243
-
-
Dunn, B.M.1
Scarborough, P.E.2
Davenport, R.3
Swietnicki, W.4
-
11
-
-
0029147617
-
Comparison of the active site specificity of the aspartic proteinases based on a systematic series of peptide substrates
-
Takahashi K, ed. New York: Plenum Press
-
Dunn BM, Scarborough PE, Lowther T, Rao-Naik C. 1995. Comparison of the active site specificity of the aspartic proteinases based on a systematic series of peptide substrates. In: Takahashi K, ed. Aspartic proteinases: Structure, function, biology, and biomedical implications 362. New York: Plenum Press, pp 1-10.
-
(1995)
Aspartic Proteinases: Structure, Function, Biology, and Biomedical Implications
, vol.362
, pp. 1-10
-
-
Dunn, B.M.1
Scarborough, P.E.2
Lowther, T.3
Rao-Naik, C.4
-
12
-
-
0024520745
-
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
-
Ho SN, Hunt HD, Horton RM, Pullen JK, Pease LR. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77:51-59.
-
(1989)
Gene
, vol.77
, pp. 51-59
-
-
Ho, S.N.1
Hunt, H.D.2
Horton, R.M.3
Pullen, J.K.4
Pease, L.R.5
-
13
-
-
0029015319
-
The initial step in the conformational folding of disulfide-intact ribonuclease A
-
Houry WA, Rothwarf DM, Scheraga HA. 1995. The initial step in the conformational folding of disulfide-intact ribonuclease A. Nat Struct Biol 2:495-503.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 495-503
-
-
Houry, W.A.1
Rothwarf, D.M.2
Scheraga, H.A.3
-
14
-
-
0027170695
-
Model peptides to study the effects of P2 and P3 substitutions in statine-containing HIV proteinase inhibitors
-
Hui KY, Hermann RB, Manetta JV, Gygi T, Angleton EL. 1993. Model peptides to study the effects of P2 and P3 substitutions in statine-containing HIV proteinase inhibitors. FEBS Lett 527:355-360.
-
(1993)
FEBS Lett
, vol.527
, pp. 355-360
-
-
Hui, K.Y.1
Hermann, R.B.2
Manetta, J.V.3
Gygi, T.4
Angleton, E.L.5
-
15
-
-
2642660087
-
Folding and association versus misfolding and aggregation of proteins
-
Jaenicke R. 1995. Folding and association versus misfolding and aggregation of proteins. Protein Folding 25:1221-1345.
-
(1995)
Protein Folding
, vol.25
, pp. 1221-1345
-
-
Jaenicke, R.1
-
16
-
-
0028277270
-
Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-beta by cathepsin D
-
Ladror US, Snyder SW, Wang GT, Holzman TF, Krafft GA. 1994. Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-beta by cathepsin D. J Bio Chem 269:18422-18428.
-
(1994)
J Bio Chem
, vol.269
, pp. 18422-18428
-
-
Ladror, U.S.1
Snyder, S.W.2
Wang, G.T.3
Holzman, T.F.4
Krafft, G.A.5
-
18
-
-
0023009774
-
Production of biologically active fragments of parathyroid hormone by isolated Kupffer cells
-
Pillai S, Zull J. 1986. Production of biologically active fragments of parathyroid hormone by isolated Kupffer cells. J Biol Chem 261:14919-14923.
-
(1986)
J Biol Chem
, vol.261
, pp. 14919-14923
-
-
Pillai, S.1
Zull, J.2
-
19
-
-
0027428527
-
Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: Analysis of P2-P1-P1′-P2′ variation
-
Rao C, Scarborough PE, Kay J, Batley B, Rapundalo S, Klutchko S, Taylor MD, Lunney EA, Humblet CC, Dunn BM. 1993. Specificity in the binding of inhibitors to the active site of human/primate aspartic proteinases: Analysis of P2-P1-P1′-P2′ variation. J Med Chem 36:2614-2620.
-
(1993)
J Med Chem
, vol.36
, pp. 2614-2620
-
-
Rao, C.1
Scarborough, P.E.2
Kay, J.3
Batley, B.4
Rapundalo, S.5
Klutchko, S.6
Taylor, M.D.7
Lunney, E.A.8
Humblet, C.C.9
Dunn, B.M.10
-
20
-
-
2642590659
-
Mechanism of the overexpression of the cathepsin D gene in breast cancer and consequences in the metastatic process
-
Rochefort, H. 1990. Mechanism of the overexpression of the cathepsin D gene in breast cancer and consequences in the metastatic process. Breast Can Res and Treatment 16:1-13.
-
(1990)
Breast Can Res and Treatment
, vol.16
, pp. 1-13
-
-
Rochefort, H.1
-
21
-
-
0028280553
-
Redesign of the substrate specificity of human cathepsin D: The dominant role of position 287 in the S2 subsite
-
Scarborough PE, Dunn BM. 1994. Redesign of the substrate specificity of human cathepsin D: The dominant role of position 287 in the S2 subsite. Protein Eng 7:495-502.
-
(1994)
Protein Eng
, vol.7
, pp. 495-502
-
-
Scarborough, P.E.1
Dunn, B.M.2
-
22
-
-
0027400775
-
Exploration of subsite binding specificity of human cathepsin D through kinetics and rule-based molecular modeling
-
Scarborough PE, Guruprasad K, Topham C, Richo GR, Conner GE, Blundell TL, Dunn BM. 1993. Exploration of subsite binding specificity of human cathepsin D through kinetics and rule-based molecular modeling. Protein Sci 2:264-276.
-
(1993)
Protein Sci
, vol.2
, pp. 264-276
-
-
Scarborough, P.E.1
Guruprasad, K.2
Topham, C.3
Richo, G.R.4
Conner, G.E.5
Blundell, T.L.6
Dunn, B.M.7
-
23
-
-
0027250352
-
Processing of the beta-amyloid precursor. Multiple proteases generate and degrade potentially amyloidogenic fragments
-
Siman R, Mistretta JT, Durkin MJ, Savage LT, Trusko S, Scott RW. 1993. Processing of the beta-amyloid precursor. Multiple proteases generate and degrade potentially amyloidogenic fragments. J Biol Chem 268:16602-16609.
-
(1993)
J Biol Chem
, vol.268
, pp. 16602-16609
-
-
Siman, R.1
Mistretta, J.T.2
Durkin, M.J.3
Savage, L.T.4
Trusko, S.5
Scott, R.W.6
-
24
-
-
0024412693
-
The selectivity of cathepsin D suggests an involvement of the enzyme in the generation of T-cell epitopes
-
van der Drift ACM, van Noort JM. 1989. The selectivity of cathepsin D suggests an involvement of the enzyme in the generation of T-cell epitopes. J Biol Chem 264:14159-14165.
-
(1989)
J Biol Chem
, vol.264
, pp. 14159-14165
-
-
Van Der Drift, A.C.M.1
Van Noort, J.M.2
|