Identification of macrophage populations expressing tumor necrosis factor-α mRNA in acute multiple sclerosis

Acta Neuropathologica

Volumn 95, Issue 4, 1998, Pages 373-377

  Bitsch, Andreas ^a   Da Costa, Cristiane ^a   Bunkowski, Stephanie ^a   Weber, Frank ^a   Rieckmann, Peter ^b   Brück, Wolfgang ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Macrophage; Microglia; MRP14; Multiple sclerosis; Tumor necrosis factor

Indexed keywords

CELL MARKER; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ACUTE DISEASE; ADULT; ARTICLE; CASE REPORT; CELL SUBPOPULATION; DEMYELINATION; HUMAN; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM; PRIORITY JOURNAL;

ACUTE DISEASE; ADULT; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACROPHAGES; MALE; MULTIPLE SCLEROSIS; RNA PROBES; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031952236     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050813     Document Type: Article

References (20)

1. Bauer J, Ruuls SR, Huitinga I, Dijkstra CD (1996) The role of macrophage subpopulations in autoimmune disease of the central nervous system. Histochem J 28: 83-97
2. Bhardwaj RS, Zotz C, Zwadlo Klarwasser G, Roth J, Goebeler M, Mahnke K, Falk M, Meinardus Hager G, Sorg C (1992) The calcium-binding proteins MRP8 and MRP14 form a membrane-associated heterodimer in a subset of monocytes/macrophages present in acute but absent in chronic inflammatory lesions. Eur J Immunol 22: 1891-1897
3. Breitschopf H, Suchanek G, Gould RM, Coleman DR, Lassmann H (1992) In situ hybridization with digoxigenine-labelled probes: sensitive and reliable detection method applied to myelinating rat brain. Acta Neuropathol 84: 581-587
4. Brück W, Schmied M, Suchanek G, Brück Y, Breitschopf H, Poser S, Piddlesden S, Lassmann H (1994) Oligodendrocytes in the early course of multiple sclerosis. Ann Neurol 35: 65-73
5. Brück W, Porada P, Poser S, Rieckmann P, Hanefeld F, Kretzschmar HA, Lassmann H (1995) Monocyle/macrophage differentiation in early multiple sclerosis lesions. Ann Neurol 38: 788-796
6. Brück W, Sommermeier N, Bergmann M, Zettl U, Goebel HH, Kretzschmar HA, Lassmann H (1996) Macrophages in multiple sclerosis. Immunobiology 195: 588-600
7. Cannella B, Raine CS (1995) The adhesion molecule and cytokine profile of multiple sclerosis lesions. Ann Neurol 37: 424-435
8. Hessian PA, Edgeworth J, Hogg N (1993) MRP-8 and MRP-14, two abundant Ca(2+)-binding proteins of neutrophils and monocytes. J Leukoc Biol 53: 197-204
9. Logel J, Dill D, Leonard S (1992) Synthesis of cRNA probes from PCR-generated DNA. Biotechniques 13: 604-610
10. Mahnke K, Bhardwaj R, Sorg C (1995) Heterodimers of the calcium-binding proteins MRP8 and MRP14 are expressed on the surface of human monocytes upon adherence to fibronectin and collagen. Relation to TNF-α, IL-6, and Superoxide production. J Leukoc Biol 57: 63-71
11. Odink K, Cerietti N, Bruggen J, Clerc RG, Tarcsay L, Zwadlo G, Gerhards G, Schlegel R, Sorg C (1987) Two calcium-binding proteins in infiltrate macrophages of rheumatoid arthritis. Nature 330: 80-82
12. Radzun HJ, Hansmann ML, Heidebrecht HJ, et al (1991) Detection of a monocyte/macrophage differentiation antigen in routinely processed paraffin-embedded tissues by monoclonal antibody KiM1P. Lab Invest 65: 306-315
13. Rieckmann P, Albrecht M, Ehrenreich H, Weber T, Michel U (1995) Semi-quantitative analysis of cytokine gene expression in blood and cerebrospinal fluid cells by reverse transcriptase polymerase chain reaction. Res Exp Med (Berl) 195: 17-29
14. Rieckmann P, Albrecht M, Kitze B, Weber T, Tumani H, Broocks A, Luer W, Helwig A, Poser S (1995) Tumor necrosis factor-alpha messenger RNA expression in patients with relapsing-remitting multiple sclerosis is associated with disease activity. Ann Neurol 37: 82-88
15. Ruddle NH, Bergman CM, McGrath KM, Lingenheld EG, Grunnet ML, Padula SJ, Clark RB (1990) An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J Exp Med 172: 1193-1200
16. Selmaj KW, Raine CS (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23: 339-346
17. Selmaj K, Raine CS, Cannella B, Brosnan CF (1991) Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin luvest 87: 949-954
18. Selmaj K, Raine CS, Cross AH (1991) Anti-tumor necrosis factor therapy abrogates autoimmune demyelination. Ann Neurol 30: 694-700
19. Selmaj K, Papierz W, Glabinski A, Kohno T (1995) Prevention of chronic relapsing experimental autoimmune encephalo-myelitis by soluble tumor necrosis factor receptor I. J Neuroimmunol 56: 135-141
20. Woodroofe MM, Cuzner ML (1993) Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization. Cytokine 5: 583-588