Relevance of kinetochore size and microtubule-binding capacity for stable chromosome attachment during mitosis in PtK1 cells

Chromosome Research

Volumn 6, Issue 2, 1998, Pages 123-132

  McEwen, Bruce F ^a,b   Ding, Ye ^a   Heagle, Amy B ^a  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Cell division; Chromosome; Kinetochore; Microtubule; Mitosis; Vertebrate cell

Indexed keywords

PACLITAXEL;

ANAPHASE; ANIMAL CELL; ARTICLE; CENTROMERE; CHROMOSOME; CHROMOSOME SIZE; ELECTRON MICROSCOPY; METAPHASE CHROMOSOME; MICROTUBULE; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CHROMOSOMES; EPITHELIAL CELLS; IMAGE PROCESSING, COMPUTER-ASSISTED; KINETOCHORES; MACROPODIDAE; METAPHASE; MICROTUBULES; MITOSIS;

EID: 0031952218     PISSN: 09673849     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009239013215     Document Type: Article

References (38)

1. Belmont LD, Hyman AA, Sawin KE, Mitchison TJ (1990) Realtime visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts. Cell 62: 579-589.
2. Bickel PJ, Doksum KA (1977) Mathematical Statistics: Basic Ideas & Selected Topics. Oakland, CA: Holden Day.
3. Carminati JL, Stearns T (1997) Microtubules orient the mitotic spindle in yeast through dynein-dependent interactions with the cell cortex. J Cell Biol 138: 629-641.
4. 1 cells. J Cell Sci 96: 9-15.
5. Cherry LM, Johnston DA (1987) Size variation in kinetochores of human chromosomes. Hum Genet 75: 155-158.
6. Cherry LM, Faulkner AJ, Grossberg LA, Balczon R (1989) Kinetochore size variation in mammalian chromosomes: an image analysis study with evolutionary implications. J Cell Sci 92: 281-289.
7. Ding R, McDonald KL, McIntosh R (1993) Three-dimensional reconstruction and analysis of mitotic spindles from the yeast, Schizosaccharomyces pombe. J Cell Biol 120: 141-151.
8. Frank J, Radermacher M, Penczek P et al. (1996) SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol 116: 190-199.
9. Fuge H (1978) Ultrastructure of the mitotic spindle. Int Rev Cytol 6 (Suppl.): 1-58.
10. Gorbsky GJ, Sammak PJ, Borisy GG (1988) Microtubule dynamics and chromosome motion visualized in living anaphase cells. J Cell Biol 106: 1185-1192.
11. Hayden JH, Bowser, SS, Rieder, CL (1990) Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cells. J Cell Biol 111: 1039-1045.
12. Hays TS, Salmon ED (1990) Poleward force at the kinetochore in metaphase depends on the number of kinetochore microtubules. J Cell Biol 110: 391-404.
13. Inoue S, Salmon ED (1995) Force generation by microtubule assembly/disassembly in mitosis and related movements. Mol Biol Cell 6: 1619-1640.
14. Jensen CG (1982) Dynamics of spindle microtubule organization: kinetochore fiber microtubules of plant endosperm. J Cell Biol 92: 540-558.
15. Levan A, Nichols WW, Peluse M, Coriell LL (1966) The stemline chromosomes of three cell lines representing different vertebrate classes. Chromosoma (Berl) 18: 343-358.
16. Levan G (1970) Contributions to the chromosomal characterization of the PTK 1 rat-kangaroo cell line. Hereditas 64: 85-96.
17. Li X, Nicklas RB (1995) Mitotic forces control a cell-cycle checkpoint. Nature 373: 630-632.
18. Lin H-P P, Ault JG, Church K (1981) Meiosis in Drosophila melanogaster. I. Chromosome identification and kinetochore microtubule numbers during the first and second meiotic divisions in males. Chromosoma (Berl) 83: 507-521.
19. McDonald KL, O'Toole ET, Mastronarde DN, McIntosh JR (1992) Kinetochore microtubules in PTK cells. J Cell Biol 118: 369-383.
20. 1 cells and its implications for the mechanisms of chromosome congression and anaphase onset. J Cell Biol 137: 1567-1580.
21. Mitchison TJ, Salmon ED (1992) Poleward kinetochore fiber movement occurs during both metaphase and anaphase-A in newt lung cell mitosis. J Cell Biol 119: 569-582.
22. Moens PB (1978) Kinetochores of grasshoppers with Robertsonian chromosome fusions. Chromosoma (Berl) 67: 41-54.
23. Moens PB (1979) Kinetochore microtubule numbers of different sized chromosomes. J Cell Biol 83: 556-561.
24. Nicklas RB (1989) The motor for poleward chromosome movement in anaphase is in or near the kinetochore. J Cell Biol 109: 2245-2255.
25. Pearson ES, Hartley HO (1972) Biometrika Tables for Statisticians, Vol. I, 3rdedn. Cambridge: Cambridge University Press.
26. Peterson JB, Ris H (1976) Electron microscopic study of the spindle and chromosome movement in the yeast Saccharomyces cerevisiae. J Cell Sci 22: 219-242.
27. Pierre RV (1985) Age and loss of the Y chromosome. In: Sanberg AA, ed. The Y Chromosome, pt B: Clinical aspects of Y Chromosome Abnormalities. New York: Liss, pp 53-60.
28. Rieder CL (1982) The formation, structure and composition of the mammalian kinetochore and kinetochore fiber. Int Rev Cytol 79: 1-58.
29. Rieder CL, Alexander SP (1990) Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells. J Cell Biol 110: 81-95.
30. Rieder CL, Salmon ED (1994) Motile kinetochores and polar ejection forces dictate chromosome position on the vertebrate mitotic spindle. J Cell Biol 124: 223-233.
31. Rieder CL, Schultz A, Cole R, Sluder G (1994) Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle. J Cell Biol 127: 1301-1310.
32. Rieder CL, Cole RW, Khodjakov A, Sluder G (1995) The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores. J Cell Biol 130: 941-948.
33. Roos U-P (1973) Light and electron microscopy of rat kangaroo cells in mitosis. II. Kinetochore structure and function. Chromosoma (Berl) 41: 195-220.
34. Skibbens RV, Petrie Skeen V, Salmon ED (1993) Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism. J Cell Biol 122: 859-875.
35. Wendell KL, Wilson L, Jordan MA (1993) Mitotic block in HeLa cells by vinblastine: ultrastructural changes in kinetochore-microtubule attachment and in centrosomes. J Cell Sci 104: 261-274.
36. Zhai Y, Kronebusch PJ, Borisy GG (1995) Kinetochore microtubule dynamics and the metaphase-anaphase transition. J Cell Biol 131: 721-734.
37. Zhang D, Nicklas RB (1997) Chromosome congression in minispindles containing a single chromosome. Mol Biol Cell 8: 171a.
38. Zinkowski RP, Meyne J, Brinkley BR (1991) The centromere-kinetochore complex: a repeat subunit model. J Cell Biol 113: 1091-1110.