-
2
-
-
0025948280
-
Molecular mechanism of slow acetylation of drugs and carcinogens in humans
-
Blum M, Demierre A, Grant DM, Heim M, Meyer UA (1991) Molecular mechanism of slow acetylation of drugs and carcinogens in humans. Proc Natl Acad Sci USA 88: 5237
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5237
-
-
Blum, M.1
Demierre, A.2
Grant, D.M.3
Heim, M.4
Meyer, U.A.5
-
3
-
-
0001679798
-
Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid
-
Breitmann T, Selenick S, Collins S (1980) Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci USA 77: 2936
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 2936
-
-
Breitmann, T.1
Selenick, S.2
Collins, S.3
-
4
-
-
0025201879
-
All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia I. Clinical results
-
Castaigne S, Chomienne C, Daniel MT, Ballerini P, Berger R, Fenaux P, Degos L (1990) All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia I. Clinical results. Blood 76: 1704
-
(1990)
Blood
, vol.76
, pp. 1704
-
-
Castaigne, S.1
Chomienne, C.2
Daniel, M.T.3
Ballerini, P.4
Berger, R.5
Fenaux, P.6
Degos, L.7
-
5
-
-
0026040363
-
A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients
-
Chen Z-X, Xue Y-Q, Zhang R, Tao R-F, Xia X-M, Li C, Wang W, Zu W-Y, Yao X-Z, Ling B-J (1991) A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients. Blood 78: 1413
-
(1991)
Blood
, vol.78
, pp. 1413
-
-
Chen, Z.-X.1
Xue, Y.-Q.2
Zhang, R.3
Tao, R.-F.4
Xia, X.-M.5
Li, C.6
Wang, W.7
Zu, W.-Y.8
Yao, X.-Z.9
Ling, B.-J.10
-
6
-
-
0027222561
-
Induction of differentiation in myeloid leukemia cell lines and acute promyelocytic leukemia cells by liposomal all-trans-retinoic acid
-
Drach J, Lopez-Berestein G, McQueen T, Andreeff M, Mehta K (1993) Induction of differentiation in myeloid leukemia cell lines and acute promyelocytic leukemia cells by liposomal all-trans-retinoic acid. Cancer Res 53: 2100
-
(1993)
Cancer Res
, vol.53
, pp. 2100
-
-
Drach, J.1
Lopez-Berestein, G.2
McQueen, T.3
Andreeff, M.4
Mehta, K.5
-
7
-
-
0030005161
-
Improved high performance liquid Chromatographic determination of debrisoquine and 4-hydroxydebrisoquine in human urine following direct injection
-
Frye RF, Branch RA (1996) Improved high performance liquid Chromatographic determination of debrisoquine and 4-hydroxydebrisoquine in human urine following direct injection. J Chromatogr 677: 178
-
(1996)
J Chromatogr
, vol.677
, pp. 178
-
-
Frye, R.F.1
Branch, R.A.2
-
8
-
-
0030712276
-
Validation of the "Pittsburgh Cocktail" approach to assess selective regulation of drug metabolizing enzymes
-
in press
-
Frye RF, Matzke GR, Adedoyin A, Porter JA, Branch RA (1997) Validation of the "Pittsburgh Cocktail" approach to assess selective regulation of drug metabolizing enzymes. Clin Pharmacol Ther (in press)
-
(1997)
Clin Pharmacol Ther
-
-
Frye, R.F.1
Matzke, G.R.2
Adedoyin, A.3
Porter, J.A.4
Branch, R.A.5
-
9
-
-
6844265349
-
A sensitive method of simultaneous determination of caffeine and its dimethylxanthine metabolites in human plasma and saliva
-
in press
-
Frye RF, Stiff DD, Branch RA, Matzke GR (1996) A sensitive method of simultaneous determination of caffeine and its dimethylxanthine metabolites in human plasma and saliva. J Chromatogr (in press)
-
(1996)
J Chromatogr
-
-
Frye, R.F.1
Stiff, D.D.2
Branch, R.A.3
Matzke, G.R.4
-
10
-
-
0028336745
-
Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva
-
Fuhr U, Rost KL (1994) Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva. Pharmacogenetics 4: 109
-
(1994)
Pharmacogenetics
, vol.4
, pp. 109
-
-
Fuhr, U.1
Rost, K.L.2
-
12
-
-
0025114258
-
Identification of the primary gene defect at the cytochrome P450 CYP2D locus
-
Gough AC, Miles JS, Spurr NK, Moss JE, Gaedigk A, Eichelbaum M, Wolf CR (1990) Identification of the primary gene defect at the cytochrome P450 CYP2D locus. Nature 347: 773
-
(1990)
Nature
, vol.347
, pp. 773
-
-
Gough, A.C.1
Miles, J.S.2
Spurr, N.K.3
Moss, J.E.4
Gaedigk, A.5
Eichelbaum, M.6
Wolf, C.R.7
-
13
-
-
0026035519
-
Role of cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
-
Guengerich FP, Kim D-H, Iwasaki M (1991) Role of cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4: 168
-
(1991)
Chem Res Toxicol
, vol.4
, pp. 168
-
-
Guengerich, F.P.1
Kim, D.-H.2
Iwasaki, M.3
-
14
-
-
0023752982
-
Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
-
Huang M-E, Ye Y-C, Chen S-R, Chai J-R, Lu J-Z, Zhoa L, Gu L-J, Wang Z-Y (1988) Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72: 567
-
(1988)
Blood
, vol.72
, pp. 567
-
-
Huang, M.-E.1
Ye, Y.-C.2
Chen, S.-R.3
Chai, J.-R.4
Lu, J.-Z.5
Zhoa, L.6
Gu, L.-J.7
Wang, Z.-Y.8
-
15
-
-
0023193252
-
Genetic predisposition to bladder cancer: Ability to hydroxylate debrisoquine and mephenytoin as risk factors
-
Kaisary A, Smith P, Jacqz E, McAllister CB, Wilkinson GR, Ray WA, Branch RA (1987) Genetic predisposition to bladder cancer: ability to hydroxylate debrisoquine and mephenytoin as risk factors. Cancer Res 47: 5488
-
(1987)
Cancer Res
, vol.47
, pp. 5488
-
-
Kaisary, A.1
Smith, P.2
Jacqz, E.3
McAllister, C.B.4
Wilkinson, G.R.5
Ray, W.A.6
Branch, R.A.7
-
16
-
-
0026486899
-
Cytochrome P4502E1 genetic polymorphism, racial variation and lung cancer
-
Kato S, Shields PG, Caporaso NE, Hoover RN, Trump BF, Sugimura H, Weston A, Harris CC (1992) Cytochrome P4502E1 genetic polymorphism, racial variation and lung cancer. Cancer Res 52: 6712
-
(1992)
Cancer Res
, vol.52
, pp. 6712
-
-
Kato, S.1
Shields, P.G.2
Caporaso, N.E.3
Hoover, R.N.4
Trump, B.F.5
Sugimura, H.6
Weston, A.7
Harris, C.C.8
-
17
-
-
6844257990
-
Phase II trial of all-trans retinoic acid in patients with adenocarcinoma
-
Kelly WK, Scher HI, Muindi J, Bajorin D, O'Moore P, Renter V, Young CW, Curley T, Liebertz C (1993) Phase II trial of all-trans retinoic acid in patients with adenocarcinoma. Proc Annu Meet Am Soc Clin Oncol 34: 1210
-
(1993)
Proc Annu Meet Am Soc Clin Oncol
, vol.34
, pp. 1210
-
-
Kelly, W.K.1
Scher, H.I.2
Muindi, J.3
Bajorin, D.4
O'Moore, P.5
Renter, V.6
Young, C.W.7
Curley, T.8
Liebertz, C.9
-
18
-
-
0020506009
-
Induction of differentiation of human acute myelogenous leukemia cells: Therapeutic implications
-
Koeffler H (1986) Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications. Blood 62: 709
-
(1986)
Blood
, vol.62
, pp. 709
-
-
Koeffler, H.1
-
19
-
-
0021680776
-
Retinoic acid metabolism by a system reconstituted with cytochrome P-450
-
Leo MA, Iida S, Lieber CS (1984) Retinoic acid metabolism by a system reconstituted with cytochrome P-450. Arch Biochem Biophys 234: 305
-
(1984)
Arch Biochem Biophys
, vol.234
, pp. 305
-
-
Leo, M.A.1
Iida, S.2
Lieber, C.S.3
-
20
-
-
0025608201
-
The contribution of N-hydroxylation and acetylation to dapsone pharmacokinetics in normal subjects
-
May G, Porter JA, Uetrecht JP, Wilkinson GR, Branch RA (1990) The contribution of N-hydroxylation and acetylation to dapsone pharmacokinetics in normal subjects. Clin Pharmacol Ther 48: 619
-
(1990)
Clin Pharmacol Ther
, vol.48
, pp. 619
-
-
May, G.1
Porter, J.A.2
Uetrecht, J.P.3
Wilkinson, G.R.4
Branch, R.A.5
-
21
-
-
0026749315
-
Influence of cirrhosis on the disposition of dapsone
-
May DG, Arns PA, Richards WO, Porter JA, Ryder D, Fleming CM, Wilkinson GR, Branch RA (1992) Influence of cirrhosis on the disposition of dapsone. Clin Pharmacol Ther 51: 689
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 689
-
-
May, D.G.1
Arns, P.A.2
Richards, W.O.3
Porter, J.A.4
Ryder, D.5
Fleming, C.M.6
Wilkinson, G.R.7
Branch, R.A.8
-
22
-
-
0026690689
-
Clinical pharmacology of oral all-trans-retinoic acid in patients with acute promyelocytic leukemia
-
Muindi JRF, Frankel SR, Huselton C, DeGrazia F, Garland WA, Young CW, Warrell RP Jr (1992) Clinical pharmacology of oral all-trans-retinoic acid in patients with acute promyelocytic leukemia. Cancer Res 52: 2138
-
(1992)
Cancer Res
, vol.52
, pp. 2138
-
-
Muindi, J.R.F.1
Frankel, S.R.2
Huselton, C.3
DeGrazia, F.4
Garland, W.A.5
Young, C.W.6
Warrell Jr., R.P.7
-
23
-
-
0026536835
-
Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: Implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia
-
Muindi J, Frankel SR, Miller WH Jr, Jakubowski A, Scheinberg DA, Young CW, Dmitrovsky E, Warrell RP Jr (1992) Continuous treatment with all-trans retinoic acid causes a progressive reduction in plasma drug concentrations: implications for relapse and retinoid "resistance" in patients with acute promyelocytic leukemia. Blood 79: 299
-
(1992)
Blood
, vol.79
, pp. 299
-
-
Muindi, J.1
Frankel, S.R.2
Miller Jr., W.H.3
Jakubowski, A.4
Scheinberg, D.A.5
Young, C.W.6
Dmitrovsky, E.7
Warrell Jr., R.P.8
-
24
-
-
0027462860
-
Lipid hydroperoxides greatly increase the rate of oxidutive catabolism of all-trans-retinoic acid by human cell culture microsomes genetically enriched in specified cytochrome P-450 isoforms
-
Muindi JF, Young CW (1993) Lipid hydroperoxides greatly increase the rate of oxidutive catabolism of all-trans-retinoic acid by human cell culture microsomes genetically enriched in specified cytochrome P-450 isoforms. Cancer Res 53: 1226
-
(1993)
Cancer Res
, vol.53
, pp. 1226
-
-
Muindi, J.F.1
Young, C.W.2
-
26
-
-
0027524546
-
Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole
-
Rigas JR, Francis PA, Muindi JRF, Kris MG, Huselton C, DeGrazia F, Orazem JP, Young CW, Warrell RP Jr (1993) Constitutive variability in the pharmacokinetics of the natural retinoid, all-trans-retinoic acid, and its modulation by ketoconazole. J Natl Cancer Inst 85: 1921
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1921
-
-
Rigas, J.R.1
Francis, P.A.2
Muindi, J.R.F.3
Kris, M.G.4
Huselton, C.5
DeGrazia, F.6
Orazem, J.P.7
Young, C.W.8
Warrell Jr., R.P.9
-
27
-
-
0018876924
-
Metabolism of all-trans-retinoic acid in hamster liver microsomes: Oxidation of 4-hydroxy- To 4-keto-retinoic acid
-
Roberts AB, Lamb LC, Sporn MB (1980) Metabolism of all-trans-retinoic acid in hamster liver microsomes: oxidation of 4-hydroxy- to 4-keto-retinoic acid. Arch Biochem Biophys 199: 374
-
(1980)
Arch Biochem Biophys
, vol.199
, pp. 374
-
-
Roberts, A.B.1
Lamb, L.C.2
Sporn, M.B.3
-
28
-
-
0020064215
-
Increased metabolism of retinoic acid after chronic ethanol consumption in rat liver microsomes
-
Sato M, Lieber CS (1982) Increased metabolism of retinoic acid after chronic ethanol consumption in rat liver microsomes. Arch Biochem Biophys 213: 517
-
(1982)
Arch Biochem Biophys
, vol.213
, pp. 517
-
-
Sato, M.1
Lieber, C.S.2
-
29
-
-
0001964818
-
Retinoids and epithelial differentiation
-
Sherman M (ed) CRC Press, Boca Raton
-
Shapiro S (1986) Retinoids and epithelial differentiation. In: Sherman M (ed) Retinoids and cell differentiation. CRC Press, Boca Raton, pp 25-59
-
(1986)
Retinoids and Cell Differentiation
, pp. 25-59
-
-
Shapiro, S.1
-
30
-
-
0027081810
-
Phase I and pharmacokinetic evaluation of all-trans-retinoic acid in pediatric patients with cancer
-
Smith MA, Adamson PC, Balis FM, Feusner J, Aromson L, Murphy RF, Horowitz ME, Reaman G, Hammond GD, Fenton RM, Connaghan GD, Hiettelman WN, Poplack DG (1992) Phase I and pharmacokinetic evaluation of all-trans-retinoic acid in pediatric patients with cancer. J Clin Oncol 10: 1666
-
(1992)
J Clin Oncol
, vol.10
, pp. 1666
-
-
Smith, M.A.1
Adamson, P.C.2
Balis, F.M.3
Feusner, J.4
Aromson, L.5
Murphy, R.F.6
Horowitz, M.E.7
Reaman, G.8
Hammond, G.D.9
Fenton, R.M.10
Connaghan, G.D.11
Hiettelman, W.N.12
Poplack, D.G.13
-
31
-
-
0027393924
-
Sensitive high-performance liquid Chromatographic determination of chlorzoxazone and 6-hydroxychlorzoxazone in plasma
-
Stiff DD, Frye RF, Branch RA (1993) Sensitive high-performance liquid Chromatographic determination of chlorzoxazone and 6-hydroxychlorzoxazone in plasma. J Chromatogr 613: 127
-
(1993)
J Chromatogr
, vol.613
, pp. 127
-
-
Stiff, D.D.1
Frye, R.F.2
Branch, R.A.3
-
32
-
-
0028607257
-
Retinoids in bladder cancer, testis and prostate cancer: Epidemiologic, preclinical and clinical observations
-
Trump DL (1994) Retinoids in bladder cancer, testis and prostate cancer: epidemiologic, preclinical and clinical observations. Leukemia 8: S50
-
(1994)
Leukemia
, vol.8
-
-
Trump, D.L.1
-
33
-
-
0031014516
-
A phase two trial of all-transretinoic acid in hormone refractory prostate cancer: A clinical trial with detailed pharmacokinetic study
-
Trump DL, Smith DC, Stiff D, Adedoyin A, Day R, Whiteside T, Bahnson RC, Hofacker J, Branch RA (1997) A phase two trial of all-transretinoic acid in hormone refractory prostate cancer: a clinical trial with detailed pharmacokinetic study. Cancer Chemother Pharmacol 39: 349
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 349
-
-
Trump, D.L.1
Smith, D.C.2
Stiff, D.3
Adedoyin, A.4
Day, R.5
Whiteside, T.6
Bahnson, R.C.7
Hofacker, J.8
Branch, R.A.9
-
34
-
-
0023916061
-
Ketoconazole inhibits the in vitro and in vivo metabolism of all-transretinoic acid
-
Van Wauwe JP, Coene MC, Goossens J, Van Nyen G, Cools W, Lauwers W (1988) Ketoconazole inhibits the in vitro and in vivo metabolism of all-transretinoic acid. J Pharmacol Exp Ther 245: 718
-
(1988)
J Pharmacol Exp Ther
, vol.245
, pp. 718
-
-
Van Wauwe, J.P.1
Coene, M.C.2
Goossens, J.3
Van Nyen, G.4
Cools, W.5
Lauwers, W.6
-
35
-
-
0025089911
-
Effects of cytochrome P-450 inhibitors on the in vivo metabolism of all-transretinoic acid in rats
-
Van Wauwe JP, Coene MC, Goosens J, Cools W, Monbaliu J (1990) Effects of cytochrome P-450 inhibitors on the in vivo metabolism of all-transretinoic acid in rats. J Pharmacol Exp Ther 252: 365
-
(1990)
J Pharmacol Exp Ther
, vol.252
, pp. 365
-
-
Van Wauwe, J.P.1
Coene, M.C.2
Goosens, J.3
Cools, W.4
Monbaliu, J.5
-
36
-
-
0026659954
-
Liarozole, an inhibitor of retinoic acid metabolism, exerts retinoid-mimetic effects in vivo
-
Van Wauwe J, Van Nyen G, Coene MC, Stoppie P, Cools W, Goossens J, Borghgraef P, Janssen PAT (1992) Liarozole, an inhibitor of retinoic acid metabolism, exerts retinoid-mimetic effects in vivo. J Pharmacol Exp Ther 261: 773
-
(1992)
J Pharmacol Exp Ther
, vol.261
, pp. 773
-
-
Van Wauwe, J.1
Van Nyen, G.2
Coene, M.C.3
Stoppie, P.4
Cools, W.5
Goossens, J.6
Borghgraef, P.7
Janssen, P.A.T.8
-
37
-
-
0028831941
-
Nomenclature for N-acetyltransferases
-
Vatsis KP, Weber WW, Bell DA, Dupret J-M, Price Evans DA, Grant DM, Hein DW, Lin HJ, Meyer UA, Relling MV, Sim E, Suzuki T, Yamazoe Y (1995) Nomenclature for N-acetyltransferases. Pharmacogenetics 5: 1
-
(1995)
Pharmacogenetics
, vol.5
, pp. 1
-
-
Vatsis, K.P.1
Weber, W.W.2
Bell, D.A.3
Dupret, J.-M.4
Price Evans, D.A.5
Grant, D.M.6
Hein, D.W.7
Lin, H.J.8
Meyer, U.A.9
Relling, M.V.10
Sim, E.11
Suzuki, T.12
Yamazoe, Y.13
-
38
-
-
0025882306
-
Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-transretinoic acid)
-
Warrell RP Jr, Frankel SR, Miller WH Jr, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M, Tafuri A, Jakubowski A, Gabrilove J, Gordon MS, Dmitrovsky E (1991) Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-transretinoic acid). New Engl J Med 324: 1385
-
(1991)
New Engl J Med
, vol.324
, pp. 1385
-
-
Warrell Jr., R.P.1
Frankel, S.R.2
Miller Jr., W.H.3
Scheinberg, D.A.4
Itri, L.M.5
Hittelman, W.N.6
Vyas, R.7
Andreeff, M.8
Tafuri, A.9
Jakubowski, A.10
Gabrilove, J.11
Gordon, M.S.12
Dmitrovsky, E.13
-
39
-
-
0021684926
-
Mephenytoin hydroxylation deficiency in Caucasians: Frequency of a new oxidative drug metabolism polymorphism
-
Wedlund PJ, Aslanian WA, Jacqz E, McAllister CB, Wilkinson GR, Branch RA (1984) Mephenytoin hydroxylation deficiency in Caucasians: frequency of a new oxidative drug metabolism polymorphism. Clin Pharmacol Ther 36: 773
-
(1984)
Clin Pharmacol Ther
, vol.36
, pp. 773
-
-
Wedlund, P.J.1
Aslanian, W.A.2
Jacqz, E.3
McAllister, C.B.4
Wilkinson, G.R.5
Branch, R.A.6
-
40
-
-
0021359112
-
Direct enantiomeric resolution of mephenytoin and its N-demethylated metabolite in plasma and blood using chiral capillary gas chromatography
-
Wedlund PJ, Sweetman BJ, McAllister CB, Branch RA, Wilkinson GR (1984) Direct enantiomeric resolution of mephenytoin and its N-demethylated metabolite in plasma and blood using chiral capillary gas chromatography. J Chromatogr 307: 121
-
(1984)
J Chromatogr
, vol.307
, pp. 121
-
-
Wedlund, P.J.1
Sweetman, B.J.2
McAllister, C.B.3
Branch, R.A.4
Wilkinson, G.R.5
-
41
-
-
0345067787
-
Metabolism of retinoic acid and retinol during differentiation of F9 embryonal cells
-
Williams JB, Napoli JL (1985) Metabolism of retinoic acid and retinol during differentiation of F9 embryonal cells. Proc Natl Acad Sci USA 82: 4658
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4658
-
-
Williams, J.B.1
Napoli, J.L.2
-
42
-
-
0023212895
-
Inhibition of retinoic acid metabolism by imidazole antimycotics in F9 embryonal carcinoma cells
-
Williams JB, Napoli JL (1987) Inhibition of retinoic acid metabolism by imidazole antimycotics in F9 embryonal carcinoma cells. Biochem Pharmacol 36: 1386
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 1386
-
-
Williams, J.B.1
Napoli, J.L.2
|