-
1
-
-
0015142234
-
Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axon
-
Armstrong, C.M. 1971. Interaction of tetraethylammonium ion derivatives with the potassium channels of giant axon. J. Gen. Physiol. 58:413-437.
-
(1971)
J. Gen. Physiol.
, vol.58
, pp. 413-437
-
-
Armstrong, C.M.1
-
2
-
-
0017743723
-
Inactivation of the sodium channel. II. Gating current experiments
-
Armstrong, C.M., and F. Bezanilla. 1977. Inactivation of the sodium channel. II. Gating current experiments. J. Gen. Physiol. 70:567-590.
-
(1977)
J. Gen. Physiol.
, vol.70
, pp. 567-590
-
-
Armstrong, C.M.1
Bezanilla, F.2
-
3
-
-
0026315160
-
Molecular basis of gating charge immobilization in Shaker potassium channels
-
Bezanilla, F., E. Perozo, D.M. Papazian, and E. Stefani. 1991. Molecular basis of gating charge immobilization in Shaker potassium channels. Science. 254:679-683.
-
(1991)
Science
, vol.254
, pp. 679-683
-
-
Bezanilla, F.1
Perozo, E.2
Papazian, D.M.3
Stefani, E.4
-
4
-
-
0028213205
-
+ channels: II. The components of gating currents and a model of channel activation
-
+ channels: II. The components of gating currents and a model of channel activation. Biophys. J. 66:1011-1021.
-
(1994)
Biophys. J.
, vol.66
, pp. 1011-1021
-
-
Bezanilla, F.1
Perozo, E.2
Stefani, E.3
-
5
-
-
0029586384
-
Closed and open state binding of 4-aminopyridine to the cloned human potassium channel Rv1.5
-
Bouchard, R.A., and D. Fedida. 1995. Closed and open state binding of 4-aminopyridine to the cloned human potassium channel Rv1.5. J. Pharmacol. Exp. Ther. 275:864-876.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.275
, pp. 864-876
-
-
Bouchard, R.A.1
Fedida, D.2
-
6
-
-
0027308678
-
The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes. II. Closed state reverse use-dependent block by 4-aminopyridine
-
Campbell, D.L., Y. Qu, R.L. Rasmusson, and H.C. Strauss. 1993. The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes. II. Closed state reverse use-dependent block by 4-aminopyridine. J. Gen. Physiol. 101:603-626.
-
(1993)
J. Gen. Physiol.
, vol.101
, pp. 603-626
-
-
Campbell, D.L.1
Qu, Y.2
Rasmusson, R.L.3
Strauss, H.C.4
-
7
-
-
0028575644
-
4-Aminopyridine binding and slow inactivation are mutually exclusive in rat Kv1.1 and Shaker potassium channels
-
Castle, N.A., S.R. Fadous, D.E. Logothetis, and G.K. Wang. 1994. 4-aminopyridine binding and slow inactivation are mutually exclusive in rat Kv1.1 and Shaker potassium channels. Mol. Pharmacol. 46:1175-1181.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 1175-1181
-
-
Castle, N.A.1
Fadous, S.R.2
Logothetis, D.E.3
Wang, G.K.4
-
10
-
-
14444273017
-
Gating current measurements show that 4-aminopyridine prevents open channel block of Kv1.5 by quinidine
-
Abstr.
-
Cheti, F.S.P., and D. Fedida. 1996. Gating current measurements show that 4-aminopyridine prevents open channel block of Kv1.5 by quinidine. Neuropharmacology. 35:82. (Abstr.)
-
(1996)
Neuropharmacology
, vol.35
, pp. 82
-
-
Cheti, F.S.P.1
Fedida, D.2
-
11
-
-
0026522529
-
Mechanism of 4-aminopyridine action on voltage-gated potassium channels in lymphocytes
-
Choquet, D., and H. Korn. 1992. Mechanism of 4-aminopyridine action on voltage-gated potassium channels in lymphocytes. J. Gen. Physiol. 99:217-240.
-
(1992)
J. Gen. Physiol.
, vol.99
, pp. 217-240
-
-
Choquet, D.1
Korn, H.2
-
13
-
-
0021916040
-
Evidence for a specific receptor site for lidocaine, quinidine, and bupivacaine assodated with cardiac sodium channels in guinea pig ventricular myocardium
-
Abstr.
-
Clarkson, C.W., and L.M. Hondeghem. 1985. Evidence for a specific receptor site for lidocaine, quinidine, and bupivacaine assodated with cardiac sodium channels in guinea pig ventricular myocardium. Circ. Res. 56:496-506.(Abstr.)
-
(1985)
Circ. Res.
, vol.56
, pp. 496-506
-
-
Clarkson, C.W.1
Hondeghem, L.M.2
-
14
-
-
0020059648
-
Mechanisms of action of lidocaine and quinidine on action potential duration in rabbit cardiac Purkinje fibers
-
Abstr.
-
Colatsky, T.J. 1982. Mechanisms of action of lidocaine and quinidine on action potential duration in rabbit cardiac Purkinje fibers. Circ. Res. 50:17-27.(Abstr.)
-
(1982)
Circ. Res.
, vol.50
, pp. 17-27
-
-
Colatsky, T.J.1
-
15
-
-
0026045545
-
+ channel behaves like an open-channel blocker
-
+ channel behaves like an open-channel blocker. Neuron. 7:743-753.
-
(1991)
Neuron
, vol.7
, pp. 743-753
-
-
Demo, S.D.1
Yellen, G.2
-
17
-
-
0029798467
-
Slow gating charge immobilization in the human potassium channel Kv1.5 and its prevention by 4-aminopyridine
-
Fedida, D., R. Bouchard, and F.S.P. Chen. 1996. Slow gating charge immobilization in the human potassium channel Kv1.5 and its prevention by 4-aminopyridine. J. Physiol. (Camb.). 494:377-387.
-
(1996)
J. Physiol. (Camb.)
, vol.494
, pp. 377-387
-
-
Fedida, D.1
Bouchard, R.2
Chen, F.S.P.3
-
19
-
-
0016574636
-
Proceedings: The actions of 4-aminopyridine on the delayed potassium current in skeletal muscle fibres
-
Gillespie, J.I., and O.F. Hutter. 1975. Proceedings: the actions of 4-aminopyridine on the delayed potassium current in skeletal muscle fibres. J. Physiol. (Camb.). 252:70P-71P.
-
(1975)
J. Physiol. (Camb.)
, vol.252
-
-
Gillespie, J.I.1
Hutter, O.F.2
-
20
-
-
0030956162
-
+ channels: Evidence for a trap door mechanism of activation gating
-
+ channels: evidence for a trap door mechanism of activation gating. J. Gen. Physiol. 109:527-535.
-
(1997)
J. Gen. Physiol.
, vol.109
, pp. 527-535
-
-
Holmgren, M.1
Smith, P.L.2
Yellen, G.3
-
21
-
-
0029896356
-
Molecular determinants of external barium block in Shaker potassium channels
-
Hurst, R.S., L. Toro, and E. Stefani. 1996. Molecular determinants of external barium block in Shaker potassium channels. FEBS Lett. 388:59-65.
-
(1996)
FEBS Lett.
, vol.388
, pp. 59-65
-
-
Hurst, R.S.1
Toro, L.2
Stefani, E.3
-
22
-
-
0031037598
-
External barium influences the gating charge movement of Shaker potassium channels
-
Hurst, R.S., M.J. Roux, L. Toro, and E. Stefani. 1997. External barium influences the gating charge movement of Shaker potassium channels. Biophys. J. 72:77-84.
-
(1997)
Biophys. J.
, vol.72
, pp. 77-84
-
-
Hurst, R.S.1
Roux, M.J.2
Toro, L.3
Stefani, E.4
-
23
-
-
0023611290
-
Quinidine-induced inhibition of a transient outward current in cardiac muscle
-
Imaizumi, Y., and W.R. Giles. 1987. Quinidine-induced inhibition of a transient outward current in cardiac muscle. Am. J. Physiol. 253:H704-H709.
-
(1987)
Am. J. Physiol.
, vol.253
-
-
Imaizumi, Y.1
Giles, W.R.2
-
24
-
-
0025689759
-
+ current in rat melanotrophs
-
+ current in rat melanotrophs. J. Physiol. (Camb.). 431:515-528.
-
(1990)
J. Physiol. (Camb.)
, vol.431
, pp. 515-528
-
-
Kehl, S.J.1
-
25
-
-
0025869350
-
+ current in rat melanotrophs
-
+ current in rat melanotrophs. Br. J. Pharmacol. 103: 1807-1813.
-
(1991)
Br. J. Pharmacol.
, vol.103
, pp. 1807-1813
-
-
Kehl, S.J.1
-
26
-
-
0018394187
-
4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers
-
Kenyon, J.L., and W.R. Gibbons. 1979. 4-Aminopyridine and the early outward current of sheep cardiac Purkinje fibers. J. Gen. Physiol. 73:139-157.
-
(1979)
J. Gen. Physiol.
, vol.73
, pp. 139-157
-
-
Kenyon, J.L.1
Gibbons, W.R.2
-
28
-
-
0027428410
-
Gating-dependent mechanism of 4-aminopyridine block in two related potassium channels
-
Kirsch, G.E., and J.A. Drewe. 1993. Gating-dependent mechanism of 4-aminopyridine block in two related potassium channels. J. Gen. Physiol. 102:797-816.
-
(1993)
J. Gen. Physiol.
, vol.102
, pp. 797-816
-
-
Kirsch, G.E.1
Drewe, J.A.2
-
29
-
-
0020520663
-
Site of action and active form of aminopyridines in squid axon membranes
-
Kirsch, G.E., and T. Narahashi. 1983. Site of action and active form of aminopyridines in squid axon membranes. J. Pharmacol. Exp. Ther. 226:174-179.
-
(1983)
J. Pharmacol. Exp. Ther.
, vol.226
, pp. 174-179
-
-
Kirsch, G.E.1
Narahashi, T.2
-
33
-
-
0027379844
-
Functional and biochemical characterization of the human potassium channel Kv1.5 with a transplanted carboxyl-terminal epitope in stable mammalian cell lines
-
Philipson, L.H., A. Malayev, A. Kuznetsov, C. Chang, and D.J. Nelson. 1993. Functional and biochemical characterization of the human potassium channel Kv1.5 with a transplanted carboxyl-terminal epitope in stable mammalian cell lines. Biochim. Biophys. Acta. 1153:111-121.
-
(1993)
Biochim. Biophys. Acta.
, vol.1153
, pp. 111-121
-
-
Philipson, L.H.1
Malayev, A.2
Kuznetsov, A.3
Chang, C.4
Nelson, D.J.5
-
36
-
-
0024386303
-
Use-dependent effects of 4-aminopyridine on transient outward current in dog ventricular muscle
-
Simurda, J., M. Simurdová, and G. Christe. 1989. Use-dependent effects of 4-aminopyridine on transient outward current in dog ventricular muscle. Pflügers Arch. 415:244-246.
-
(1989)
Pflügers Arch.
, vol.415
, pp. 244-246
-
-
Simurda, J.1
Simurdová, M.2
Christe, G.3
-
37
-
-
0028325440
-
+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes
-
Abstr.
-
+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes. J. Pharmacol. Exp. Ther. 269:66-74.(Abstr.)
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 66-74
-
-
Slawsky, M.T.1
Castle, N.A.2
-
38
-
-
0026603450
-
Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel
-
Snyders, D.J., K.M. Knoth, S.L. Roberds, and M.M. Tamkun. 1992. Time-, voltage-, and state-dependent block by quinidine of a cloned human cardiac potassium channel. Mol. Pharmacol. 41:322-330.
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 322-330
-
-
Snyders, D.J.1
Knoth, K.M.2
Roberds, S.L.3
Tamkun, M.M.4
-
39
-
-
0029130666
-
Determinants of antiarrhythmic drug action: Electrostatic and hydro-phobic components of block of the human cardiac hKv1.5 channel
-
Snyders, D.J., and S.W. Yeola. 1995. Determinants of antiarrhythmic drug action: electrostatic and hydro-phobic components of block of the human cardiac hKv1.5 channel. Circ. Res. 77:575-583.
-
(1995)
Circ. Res.
, vol.77
, pp. 575-583
-
-
Snyders, D.J.1
Yeola, S.W.2
-
41
-
-
0028364122
-
On the mechanism of 4-aminopyridine action on the cloned mouse brain potassium channel mKv1.1
-
Stephens, G.J., J.C. Garratt, B. Robertson, and D.G. Owen. 1994. On the mechanism of 4-aminopyridine action on the cloned mouse brain potassium channel mKv1.1. J. Physiol. (Camb.). 477: 187-196.
-
(1994)
J. Physiol. (Camb.)
, vol.477
, pp. 187-196
-
-
Stephens, G.J.1
Garratt, J.C.2
Robertson, B.3
Owen, D.G.4
-
42
-
-
0025736634
-
Gating currents of inactivating and non-inactivating potassium channel expressed in Xenopus oocytes
-
Stühmer, W., F. Conti, M. Stocker, O. Pongs, and S.H. Heinemann. 1991. Gating currents of inactivating and non-inactivating potassium channel expressed in Xenopus oocytes. Pflügers Arch. 410: 423-429.
-
(1991)
Pflügers Arch.
, vol.410
, pp. 423-429
-
-
Stühmer, W.1
Conti, F.2
Stocker, M.3
Pongs, O.4
Heinemann, S.H.5
-
44
-
-
0019945876
-
Aminopyridine block of transient potassium current
-
Thompson, S. 1982. Aminopyridine block of transient potassium current. J. Gen. Physiol. 80:1-18.
-
(1982)
J. Gen. Physiol.
, vol.80
, pp. 1-18
-
-
Thompson, S.1
-
45
-
-
0030432376
-
Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively
-
Tseng, G.N., B. Zhu, S. Ling, and J.A. Yao. 1996. Quinidine enhances and suppresses Kv1.2 from outside and inside the cell, respectively. J. Pharmacol. Exp. Ther. 279:844-855.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.279
, pp. 844-855
-
-
Tseng, G.N.1
Zhu, B.2
Ling, S.3
Yao, J.A.4
-
46
-
-
0017097170
-
Block of potassium channels of the nodal membrane by 4-aminopyridine and its partial removal on depolarization
-
Ulbricht, W., and H.H. Wagner. 1976. Block of potassium channels of the nodal membrane by 4-aminopyridine and its partial removal on depolarization. Pflügers Arch. 367:77-87.
-
(1976)
Pflügers Arch.
, vol.367
, pp. 77-87
-
-
Ulbricht, W.1
Wagner, H.H.2
-
47
-
-
0025604975
-
Aminopyridines block an inactivating potassium current having slow recovery kinetics
-
Wagoner, P.K., and G.S. Oxford. 1990. Aminopyridines block an inactivating potassium current having slow recovery kinetics. Biophys. J. 58:1481-1489.
-
(1990)
Biophys. J.
, vol.58
, pp. 1481-1489
-
-
Wagoner, P.K.1
Oxford, G.S.2
-
48
-
-
0028838977
-
Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes
-
Wang, Z., B. Fermini, and S. Nattel. 1995. Effects of flecainide, quinidine, and 4-aminopyridine on transient outward and ultrarapid delayed rectifier currents in human atrial myocytes. J. Pharmacol. Exp. Ther. 272:184-196.
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.272
, pp. 184-196
-
-
Wang, Z.1
Fermini, B.2
Nattel, S.3
-
50
-
-
0017089418
-
Dynamics of aminopyridine block of potassium channels in squid axon membrane
-
Yeh, J.Z., G.S. Oxford, and C.H. Wu. 1976. Dynamics of aminopyridine block of potassium channels in squid axon membrane. J. Gen. Physiol. 68:519-535.
-
(1976)
J. Gen. Physiol.
, vol.68
, pp. 519-535
-
-
Yeh, J.Z.1
Oxford, G.S.2
Wu, C.H.3
-
52
-
-
0028140472
-
Shaker potassium channel gating. III. Evaluation of kinetic models for activation
-
Zagotta, W.N., T. Hoshi, and R.W. Aldrich. 1994a. Shaker potassium channel gating. III. Evaluation of kinetic models for activation. J. Gen. Physiol. 103:321-362.
-
(1994)
J. Gen. Physiol.
, vol.103
, pp. 321-362
-
-
Zagotta, W.N.1
Hoshi, T.2
Aldrich, R.W.3
-
53
-
-
0028085276
-
Shaker potassium channel gating. II. Transitions in the activation pathway
-
Zagotta, W.N., T. Hoshi, J. Dittman, and R.W. Aldrich. 1994b. Shaker potassium channel gating. II. Transitions in the activation pathway. J. Gen. Physiol. 103:279-319.
-
(1994)
J. Gen. Physiol.
, vol.103
, pp. 279-319
-
-
Zagotta, W.N.1
Hoshi, T.2
Dittman, J.3
Aldrich, R.W.4
|