Microsatellite instability and loss of heterozygosity in gastric carcinoma in comparison to family history

American Journal of Pathology

Volumn 152, Issue 5, 1998, Pages 1281-1289

  Keller, Gisela ^a   Rudelius, Martina ^a   Vogelsang, Holger ^a   Grimm, Volker ^a   Wilhelm, Manfred Gerald ^b   Mueller, James ^a   Siewert, Jörg Rüdiger ^a   Höfler, Heinz ^c  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DINUCLEOTIDE; DNA; PROTEIN P53;

ADULT; AGED; ARTICLE; CHROMOSOME 17P; CLINICAL ARTICLE; DINUCLEOTIDE REPEAT; FAMILY HISTORY; FEMALE; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FAMILY HEALTH; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0031945119     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Boring CC, Squires TS, Tong T, Montgomery S: Cancer statistics 1994. Ca Cancer J Clin 1994, 44:7-26
2. Correa P: Human gastric carcinogenesis: a multistep and multifactorial process - First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. Cancer Res 1992, 52:6735-6740
3. Zanghieri G, di Gregorio C, Sacchetti C, Fante R, Sassatelli R, Cannizzo G, Carriero A, Ponz de Leon M: Familial occurence of gastric cancer in the 2-year experience of a population-based registery. Cancer 1990, 66:2047-2051
4. La Vecchia C, Negri E, Franceschi S, Gentile A: Family history and the risk of stomach and colorectal cancer. Cancer 1992, 70:50-55
5. Palli D, Galli M, Caporaso NE, Cipriani F, Decarli A, Saieva C, Fraumeni JF, Buiatti E: Family history and risk of stomach cancer in Italy. Cancer Epidemiol Biomarkers Prev 1994, 3:15-18
6. Lethola J: Family study of gastric carcinoma with special reference to histological types. Scand J Gastroenterol 1978, 13(Suppl 50):1-73
7. Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, Cavalieri J, Boland RC: Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 1993, 104:1535-1549
8. Peltomäki P, Vasen HF: Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. The International Collaborative Group on Hereditary Nonpolyposis Cancer. Gastroenterology 1997, 113:1146-1158
9. Eshleman JR, Markowitz SD: Mismatch repair defects in human carcinogenesis. Hum Mol Genet 1996, 5:1489-1494
10. Aaltonen LA, Peltomäki P, Leach FS, Sistonen P, Pylkkänen L, Mecklin J-P, Järvinen H, Powell SM, Jen J, Hamilton SR, Petersen GM, Kinzler KW, Vogelstein B, de la Chapelle A: Clues to the pathogenesis of familial colorectal cancer. Science 1993, 260:812-816
11. Peltomäkie P, Lothe RA, Aaaltonen LA, Pylkkänen L, Nyström-Lathi M, Seruca R, David L, Holm R, Ryberg D, Haugen A, Brogger A, Borresen AL, de la Chapelle A: Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res 1993, 53:5853-5855
12. Han HJ, Yanagisawa A, Kato Y, Park JG, Nakamura Y: Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res 1993, 53:5078-5089
13. Rhyu MG, Park WS, Meltzer SJ: Microsatellite instability occurs frequently in human gastric carcinoma. Oncogene 1994, 9:29-32
14. n DNA repeats and tumor suppressor genes in human gastric cancer. Cancer Res 1994, 54:41-44
15. Chong JM, Fukayama M, Hayashi Y, Takizawa T, Koike M, Konishi M, Kikuchi-Yanoshita R, Miyaki M: Microsatellite instability in the progression of gastric carcinoma. Cancer Res 1994, 54:4595-4597
16. Strickler JG, Zheng J, Shu Q, Burgart LJ, Alberts SR, Shibata D: p53 mutations and microsatellite instability in sporadic gastric cancer: when guardians fail. Cancer Res 1994, 54:4750-4755
17. Tamura G, Sakata K, Maesawa C, Suzuki Y, Terashima M, Satoh K, Seliyama S, Suzuki A, Eda Y, Satodate R: Microsatellite alterations in adenoma and differentiated adenocarcinoma of the stomach Cancer Res 1995, 55:1933-1936
18. Lin JT, Wu MS, Shun CT, Lee WJ, Wang JT, Wang TH, Sheu JC: Microsatellite instability in gastric carcinoma with special references to histopathology and cancer stages. Eur J Cancer 1995, 31A:1879-1882
19. Keller G, Rotter M, Vogelsang H, Bischoff P, Becker K-F, Mueller J, Brauch H, Siewert JR, Höfler H: Microsatellite instability in adenocarcinomas of the upper gastrointestinal tract. Am J Pathol 1995, 147: 593-600
20. dos Santos NR, Seruca R, Constancia M, Seixas M, Sobrinho-Simoes M: Microsatellite instability at multiple loci in gastric carcinoma: clinicopathologic implications and prognosis. Gastroenterology 1996, 110:38-44
21. Chung YJ, Song JM, Lee JY, Jung YT, Seo EJ, Choi SW, Rhyu MG: Microsatellite instability-associated mutations associate preferentially with the intestinal type of primary gastric carcinomas in a high-risk population. Cancer Res 1996, 56:4662-4665
22. Renault B, Calistri D, Buonsanti G, Nanni O, Amadori D, Ranzani GN: Microsatellite instability and mutations of p53 and TGF-β Rll genes in gastric cancer. Hum Genet 1996, 98:601-607
23. Semba S, Yokozaki H, Yamamoto S, Yasui W, Tahara E: Microsatellite instability in precancerous lesions and adenocarcinomas of the stomach. Cancer 1996, 77:1620-1627
24. Buonsanti G, Calistri D, Padovan L, Luinette O, Fiocca R, Solicia E, Ranzani GN: Microsatellite instability in intestinal- and diffuse-type gastric carcinoma. J Pathol 1997, 182:167-173
25. Ottini L, Palli D, Falchetti M, D'Amico C, Amorosi A, Saieva C, Calzolari A, Cimoli F, Taraelli C, De Marchis L, Masala G, Mariani-Costantini R, Cama A: Microsatellite instability in gastric cancer is associated with tumor location and family history in a high-risk population from Tuscany. Cancer Res 1997, 57:4523-4529
26. Keller G, Grimm V, Vogelsang H, Bischoff P, Mueller J, Siewert JR, Höfler H: Analysis for microsatellite instability and mutations of the DNA mismatch repair gene hMLH1 in familial gastric cancer. Int J Cancer 1996, 68:571-576
27. Tahara E: Genetic alterations in human gastrointestinal cancers. Cancer 1995, 75:1410-1417
28. Becker KFM, Atkinson U, Reich I, Becker H, Nekarda J, Sievert JR, Höfler H: E-cadherin gene mutations provide clues to diffuse type gastric carcinomas Cancer Res 54:3845-3852
29. UICC International Union Against Cancer: TNM Atlas. Edited by B Spiessl, OH Beahrs, P Hermanek, RVP Hutter, O Scheibe, LH Sobin, G Wagner. Berlin, Heidelberg, Springer-Verlag, 1992
30. World Health Organization: Histological Typing of Oesophageal and Gastric Tumours. Edited by H Watanabe, JR Jass, LH Sobin. Berlin, Heidelberg, Springer-Verlag, 1990
31. Laurén P: The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type of carcinoma. Acta Pathol Microbiol Scand 1965, 64:31-49
32. Beckmann MW, Picard F, An HX, van Roeyen CRC, Dominik SI, Mosny DS, Schnürch HG, Bender HG, Niederacher D: Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer. Br J Cancer 1996, 73:1220-1226
33. Gleeson CM, Sloan JM, McGuigan JA, Ritchie AJ, Weber JL, Russell SEH: Widespread microsatellite instability occurs infrequently in adenocarcinoma of the gastric cardia Oncogene 1996, 12:1653-1662
34. Thiobodeau SN, Bren G, Schaid D: Microsatellite instability in cancer of the proximal colon. Science 1993, 260:816
35. Honchel R, Hailing KC, Thiobodeau SN: Genomic instability in neoplasia. Semin Cell Biol 1995, 6:45-52
36. Papadopoulos N, Nicolaides NC, Liu B, Parsons R, Lengauer C, Palombo F, D'Arrigo A, Markowitz S, Willson JKV, Kinzler KW, Jiricny J, Vogelstein B: Mutations of GTBP in genetically unstable cells. Science 1995, 268:1915-1917
37. Simpson AJ: The natural somatic mutation frequency and human carcinogenesis. Adv Cancer Res 1997, 71:209-240
38. Amos W, Sawcer SJ, Feakes RW, Rubinsztein DC: Microsatellites show mutational bias and heterozygote instability. Nat Genet 1996, 13:390-391
39. Glebov OK, McKenzie KE, White CA, Sukumar S: Frequent p53 gene mutations and novel alleles in familial breast cancer. Cancer Res 1994, 54:3703-3709
40. Ryberg D, Lindstedt BA, Zienolddiny S, Haugen A: A hereditary genetic factor closely associated with microsatellite instability in lung cancer. Cancer Res 1995, 55:3996-3999
41. Lindstedt BA, Ryberg D, Haugen A: Rare alleles at different VNTR loci among lung-cancer patients with microsatellite instability in tumours, Int J Cancer 1997, 70:412-415
42. Shinmura K, Yin W, Isogaki J, Saitoh K, Kanazawa K, Koda K, Yokota J, Kino I, Arai T, Sugimura H: Stage-dependent evaluation of microsatellite instability in gastric carcinoma with familial clustering. Cancer Epidemiol Biomarkers Prev 1997, 6:693-697
43. Fey MF, Hesketh C, Wainscoat JS, Gendler S, Thein SL: Clonal allele loss in gastrointestinal cancer. Br J Cancer 1989, 59:750-754
44. Sano T, Tsujino T, Yoshida K, Nakayama H, Haruma K, Ito H, Nakamura Y, Kajiyama G, Tahara E: Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas. Cancer Res 1991, 51:2926-2931
45. Ranzani GN, Renault B, Pellegata NS, Fattorini P, Magni E, Bacci F, Amadori D: Loss of heterozygosity and K-ras mutations in gastric cancer. Hum Genet 1993, 92:244-249
46. Baker SJ, Fearon ER, Nigro JM, Hamilton SR, Preisinger AC, Jessup JM, van Tuinen P, Ledbetter DH, Baker DF, Nakamura Y, White R, Vogelstein B: Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 1989, 244:217-221
47. Lim BHG, Soong R, Grieu F, Robbins PD, House AK, Iacopetta BJ: p53 accumulation and mutation are prognostic indicators of poor survival in human gastric carcinoma. Int J Cancer 1996, 69:200-204
48. Gabbert HE, Müller W, Schneiders A, Meier S, Hommel G: The relationship of p53 expression to the prognosis of 418 patients with gastric carcinoma. Cancer 1995, 76:720-726
49. Soong R, Robbins PD, Dix BR, Grieu F, Lim B, Knowles S, Williams KE, Turbett GR, House AK, lacopetta BJ: Concordance between p53 protein overexpression and gene mutation in a large series of common human carcinomas. Hum Pathol 1996, 27:1050-1055
50. Baas IO, Mulder JWR, Offerhaus JA, Vogelstein B, Hamilton SR: An evaluation of six antibodies for immunhistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994, 172: 5-12