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Volumn 257, Issue 6, 1998, Pages 662-671

Switch-domain mutations in the Saccharomyces cerevisiae G protein α-subunit Gpa1p identify a receptor subtype-biased mating defect

Author keywords

G proteins; Mating; Pheromone response

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; PHEROMONE; PROTEIN SUBUNIT; RAS PROTEIN;

EID: 0031945024     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050695     Document Type: Article
Times cited : (3)

References (75)
  • 1
    • 0024966005 scopus 로고
    • Constitutive mutants in the yeast pheromone response: Ordered function of the gene products
    • Blinder D, Bouvier S, Jenness DD (1989) Constitutive mutants in the yeast pheromone response: ordered function of the gene products. Cell 56:479-486
    • (1989) Cell , vol.56 , pp. 479-486
    • Blinder, D.1    Bouvier, S.2    Jenness, D.D.3
  • 2
    • 0021668558 scopus 로고
    • A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance
    • Boeke JD, LaCrouto F, Fink GR (1984) A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet 197:345-346
    • (1984) Mol Gen Genet , vol.197 , pp. 345-346
    • Boeke, J.D.1    LaCrouto, F.2    Fink, G.R.3
  • 3
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos JL (1989) ras oncogenes in human cancer: a review. Cancer Res 40:4682-4689
    • (1989) Cancer Res , vol.40 , pp. 4682-4689
    • Bos, J.L.1
  • 4
    • 0020040057 scopus 로고
    • Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a-factor and α-factor pheromones
    • Chan RK, Otte CA (1982) Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a-factor and α-factor pheromones. Mol Cell Biol 2:11-20
    • (1982) Mol Cell Biol , vol.2 , pp. 11-20
    • Chan, R.K.1    Otte, C.A.2
  • 5
    • 0030923134 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Mpt5p interacts with Sst2p and plays roles in pheromone sensitivity and recovery from pheromone arrest
    • Chen T, Kurjan J (1997) Saccharomyces cerevisiae Mpt5p interacts with Sst2p and plays roles in pheromone sensitivity and recovery from pheromone arrest. Mol Cell Biol 17:3429-3439
    • (1997) Mol Cell Biol , vol.17 , pp. 3429-3439
    • Chen, T.1    Kurjan, J.2
  • 7
    • 0027434614 scopus 로고
    • Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating
    • Clark KL, Dignard D, Thomas DY, Whiteway M (1993) Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating. Mol Cell Biol 13:1-8
    • (1993) Mol Cell Biol , vol.13 , pp. 1-8
    • Clark, K.L.1    Dignard, D.2    Thomas, D.Y.3    Whiteway, M.4
  • 9
    • 0027318238 scopus 로고
    • Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors
    • Conklin BR, Bourne HR (1993) Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors. Cell 73:631-641
    • (1993) Cell , vol.73 , pp. 631-641
    • Conklin, B.R.1    Bourne, H.R.2
  • 10
    • 0022471217 scopus 로고
    • Biological and biochemical properties of human rasH genes mutated at codon 61
    • Der CJ, Finkel T, Cooper GM (1986) Biological and biochemical properties of human rasH genes mutated at codon 61. Cell 44:167-176
    • (1986) Cell , vol.44 , pp. 167-176
    • Der, C.J.1    Finkel, T.2    Cooper, G.M.3
  • 11
    • 0023664976 scopus 로고
    • The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway
    • Dietzel C, Kurjan J (1987a) The yeast SCG1 gene: a Gα-like protein implicated in the a- and α-factor response pathway. Cell 50:1001-1010
    • (1987) Cell , vol.50 , pp. 1001-1010
    • Dietzel, C.1    Kurjan, J.2
  • 12
    • 0023460928 scopus 로고
    • Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: A model for desensitization to pheromone
    • Dietzel C, Kurjan J (1987b) Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: a model for desensitization to pheromone. Mol Cell Biol 7:4169-4177
    • (1987) Mol Cell Biol , vol.7 , pp. 4169-4177
    • Dietzel, C.1    Kurjan, J.2
  • 13
    • 0031041306 scopus 로고    scopus 로고
    • RGS proteins and signaling by heterotrimeric G proteins
    • Dohlman HG, Thorner J (1997) RGS proteins and signaling by heterotrimeric G proteins. J Biol Chem 272:3871-3874
    • (1997) J Biol Chem , vol.272 , pp. 3871-3874
    • Dohlman, H.G.1    Thorner, J.2
  • 14
    • 0028805208 scopus 로고
    • Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients
    • Dorer R, Pryciak PM, Hartwell LH (1995) Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients. J Cell Biol 131:845-861
    • (1995) J Cell Biol , vol.131 , pp. 845-861
    • Dorer, R.1    Pryciak, P.M.2    Hartwell, L.H.3
  • 16
    • 0024522512 scopus 로고
    • The mechanism of guanosine nucleotide hydrolysis by p21 c-Ha-ras: The stereo-chemical course of the GTPase reaction
    • Feuerstein J, Goody RS, Webb MR (1989) The mechanism of guanosine nucleotide hydrolysis by p21 c-Ha-ras: the stereo-chemical course of the GTPase reaction. J Biol Chem 264:6188-6190
    • (1989) J Biol Chem , vol.264 , pp. 6188-6190
    • Feuerstein, J.1    Goody, R.S.2    Webb, M.R.3
  • 17
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields S, Song O (1989) A novel genetic system to detect protein-protein interactions. Nature 340:245-246
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 19
    • 0000689283 scopus 로고    scopus 로고
    • Immunoblotting and immunodetection
    • Ausubel FA, Brent R, Kingston RE, Moore DM, Seidman JG, Smith JA, Struhl K (eds) John Wiley and Sons, New York
    • Gallagher S, Winston S, Fuller S, Hurrell YGR (1997) Immunoblotting and immunodetection. In: Ausubel FA, Brent R, Kingston RE, Moore DM, Seidman JG, Smith JA, Struhl K (eds) Current protocols in molecular biology. John Wiley and Sons, New York, pp 10.8.1-10.8.21
    • (1997) Current Protocols in Molecular Biology , pp. 1081-10821
    • Gallagher, S.1    Winston, S.2    Fuller, S.3    Hurrell, Y.G.R.4
  • 20
    • 0000811664 scopus 로고
    • Intrinsic GTPasc activity distinguishes normal and oncogenic ras p21 molecules
    • Gibbs JB, Sigal IS, Poe M, Scolnick EM (1984) Intrinsic GTPasc activity distinguishes normal and oncogenic ras p21 molecules. Proc Natl Acad Sci USA 81:5704-5708
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 5704-5708
    • Gibbs, J.B.1    Sigal, I.S.2    Poe, M.3    Scolnick, E.M.4
  • 21
    • 0024425826 scopus 로고
    • Synthesis in Escherichia coli of GTPase-deficient mutants of Gsα
    • Graziano MP, Gilman AG (1989) Synthesis in Escherichia coli of GTPase-deficient mutants of Gsα. J Biol Chem 264:15475-15482
    • (1989) J Biol Chem , vol.264 , pp. 15475-15482
    • Graziano, M.P.1    Gilman, A.G.2
  • 22
    • 0027940228 scopus 로고
    • Recombinant proteins attached to a nickel-NTA column: Use in affinity purification of antibodies
    • Gu J, Stephenson CG, Iadarola MJ (1994) Recombinant proteins attached to a nickel-NTA column: use in affinity purification of antibodies. BioTechnology 17:257-262
    • (1994) BioTechnology , vol.17 , pp. 257-262
    • Gu, J.1    Stephenson, C.G.2    Iadarola, M.J.3
  • 24
  • 25
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ (1993) The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 27
    • 0026083213 scopus 로고
    • The carboxyl terminus of Scg1, the Gα subunit involved in yeast mating, is implicated in interactions with the pheromone receptors
    • Hirsch JP, Dietzel C, Kurjan J (1991) The carboxyl terminus of Scg1, the Gα subunit involved in yeast mating, is implicated in interactions with the pheromone receptors. Genes Dev 5:467-474
    • (1991) Genes Dev , vol.5 , pp. 467-474
    • Hirsch, J.P.1    Dietzel, C.2    Kurjan, J.3
  • 28
    • 0027208625 scopus 로고
    • Identification of amino acids in p21 ras involved in exchange factor interaction
    • Howe LR, Marshall C-J (1993) Identification of amino acids in p21 ras involved in exchange factor interaction. Oncogene 8:2583-2590
    • (1993) Oncogene , vol.8 , pp. 2583-2590
    • Howe, L.R.1    Marshall, C.-J.2
  • 29
    • 0031027064 scopus 로고    scopus 로고
    • There are GAPS and there are GAPS
    • Iyengar R (1997) There are GAPS and there are GAPS. Science 275:42-43
    • (1997) Science , vol.275 , pp. 42-43
    • Iyengar, R.1
  • 30
    • 0025598073 scopus 로고
    • Courtship in S. cerevisiae: Both cell types choose mating partners by responding to the strongest pheromone signal
    • Jackson CL, Hartwell LH (1990) Courtship in S. cerevisiae: both cell types choose mating partners by responding to the strongest pheromone signal. Cell 63:1039-1051
    • (1990) Cell , vol.63 , pp. 1039-1051
    • Jackson, C.L.1    Hartwell, L.H.2
  • 31
    • 0030455820 scopus 로고    scopus 로고
    • Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast
    • James P, Halladay J, Craig EA (1996) Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics 144:1425-1436
    • (1996) Genetics , vol.144 , pp. 1425-1436
    • James, P.1    Halladay, J.2    Craig, E.A.3
  • 32
    • 0031002349 scopus 로고    scopus 로고
    • α subunit involved in the yeast pheromone response pathway
    • α subunit involved in the yeast pheromone response pathway. Mol Cell Biol 17:2897-2907
    • (1997) Mol Cell Biol , vol.17 , pp. 2897-2907
    • Kallal, L.1    Kurjan, J.2
  • 33
    • 0025353702 scopus 로고
    • Effects of expression of mammalian Gα and hybrid mammalian-yeast Gα proteins on the yeast pheromone response signal transduction pathway
    • Kang Y-S, Kane J, Kurjan J, Stadel JM, Tipper DJ (1990) Effects of expression of mammalian Gα and hybrid mammalian-yeast Gα proteins on the yeast pheromone response signal transduction pathway. Mol Cell Biol 10:2582-2590
    • (1990) Mol Cell Biol , vol.10 , pp. 2582-2590
    • Kang, Y.-S.1    Kane, J.2    Kurjan, J.3    Stadel, J.M.4    Tipper, D.J.5
  • 35
    • 0030907376 scopus 로고    scopus 로고
    • A new family of G-protein regulators the RGS proteins
    • Koelle MR (1997) A new family of G-protein regulators the RGS proteins. Curr Opin Cell Biol 9:143-147
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 143-147
    • Koelle, M.R.1
  • 36
    • 0027144459 scopus 로고
    • The pheromone response pathway in Saccharomyces cerevisiae
    • Kurjan J (1993) The pheromone response pathway in Saccharomyces cerevisiae. Ann Rev Genet 27:147-179
    • (1993) Ann Rev Genet , vol.27 , pp. 147-179
    • Kurjan, J.1
  • 37
    • 0026028177 scopus 로고
    • Mutations in the guanine nucleotide-binding domains of a yeast Gα protein confer a constitutive or uninducible state to the pheromone response pathway
    • Kurjan J, Hirsch JP, Dietzel C (1991) Mutations in the guanine nucleotide-binding domains of a yeast Gα protein confer a constitutive or uninducible state to the pheromone response pathway. Genes Dev 5:475-483
    • (1991) Genes Dev , vol.5 , pp. 475-483
    • Kurjan, J.1    Hirsch, J.P.2    Dietzel, C.3
  • 38
    • 0023058301 scopus 로고
    • Ras p21 proteins with high or low GTPase activity can efficiently transform NIH/3T3 cells
    • Lacal JC, Srivastava SK, Anderson PS, Aaronson SA (1986) Ras p21 proteins with high or low GTPase activity can efficiently transform NIH/3T3 cells. Cell 44:609-617
    • (1986) Cell , vol.44 , pp. 609-617
    • Lacal, J.C.1    Srivastava, S.K.2    Anderson, P.S.3    Aaronson, S.A.4
  • 39
    • 0028237708 scopus 로고
    • Structural determinants for activation of the α-subunit of a heterotrimeric G protein
    • Lambright DG, Noel JP, Hamm HE, Sigler PB (1994) Structural determinants for activation of the α-subunit of a heterotrimeric G protein. Nature 369:621-628
    • (1994) Nature , vol.369 , pp. 621-628
    • Lambright, D.G.1    Noel, J.P.2    Hamm, H.E.3    Sigler, P.B.4
  • 42
    • 0029106731 scopus 로고
    • α16 contribute to the specificity of activation by the C5a receptor
    • α16 contribute to the specificity of activation by the C5a receptor. Mol Pharm 47:218-223
    • (1995) Mol Pharm , vol.47 , pp. 218-223
    • Lee, C.H.1    Katz, A.2    Simon, M.I.3
  • 43
    • 0023666078 scopus 로고
    • RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C
    • Mann C, Buhler J, Treich I, Sentenac A (1987) RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C. Cell 48:627-637
    • (1987) Cell , vol.48 , pp. 627-637
    • Mann, C.1    Buhler, J.2    Treich, I.3    Sentenac, A.4
  • 45
    • 0025117674 scopus 로고
    • Molecular switch for signal transduction: Structural differences between active and inactive forms of protooncogenic ras proteins
    • Milburn MV, Tong L, deVos AM, Brunger A, Yamaizumi Z, Nisimura S, Kim S-H (1990) Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins. Science 247:939-945
    • (1990) Science , vol.247 , pp. 939-945
    • Milburn, M.V.1    Tong, L.2    DeVos, A.M.3    Brunger, A.4    Yamaizumi, Z.5    Nisimura, S.6    Kim, S.-H.7
  • 47
    • 0023665139 scopus 로고
    • GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction
    • Miyajima I, Nakafuku M, Nakayama N, Brenner C, Miyajima A, Kaibuchi K, Arai K, Kaziro Y, Matsumoto K (1987) GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction. Cell 50:1011-1019
    • (1987) Cell , vol.50 , pp. 1011-1019
    • Miyajima, I.1    Nakafuku, M.2    Nakayama, N.3    Brenner, C.4    Miyajima, A.5    Kaibuchi, K.6    Arai, K.7    Kaziro, Y.8    Matsumoto, K.9
  • 48
    • 0024678964 scopus 로고
    • Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae
    • Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae. Mol Cell Biol 9:2289-2297
    • (1989) Mol Cell Biol , vol.9 , pp. 2289-2297
    • Miyajima, I.1    Arai, K.-I.2    Matsumoto, K.3
  • 49
    • 0028178179 scopus 로고
    • Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors
    • Mosteller RD, Han J, Broek D (1994) Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors. Mol Cell Biol 14:1104-1112
    • (1994) Mol Cell Biol , vol.14 , pp. 1104-1112
    • Mosteller, R.D.1    Han, J.2    Broek, D.3
  • 50
    • 0344801103 scopus 로고
    • Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the α subunit of mammalian G proteins
    • Nakafuku M, Itoh H, Nakamura S, Kaziro Y (1987) Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the α subunit of mammalian G proteins. Proc Natl Acad Sci USA 84:2140-2144
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 2140-2144
    • Nakafuku, M.1    Itoh, H.2    Nakamura, S.3    Kaziro, Y.4
  • 51
    • 0023729456 scopus 로고
    • Role of STE genes in the mating-factor signaling pathway mediated by GPA1 in Saccharomyces cerevisiae
    • Nakayama N, Kaziro Y, Arai K-I, Matsumoto K (1988) Role of STE genes in the mating-factor signaling pathway mediated by GPA1 in Saccharomyces cerevisiae. Mol Cell Biol 8:3777-3783
    • (1988) Mol Cell Biol , vol.8 , pp. 3777-3783
    • Nakayama, N.1    Kaziro, Y.2    Arai, K.-I.3    Matsumoto, K.4
  • 52
    • 0028860268 scopus 로고
    • Heterotrimeric G proteins: Organizers of transmembrane signals
    • Neer EJ (1995) Heterotrimeric G proteins: organizers of transmembrane signals. Cell 80:249-257
    • (1995) Cell , vol.80 , pp. 249-257
    • Neer, E.J.1
  • 53
    • 0027132717 scopus 로고
    • The 2.2 Å crystal structure of transducin-α complexed with GTPγS
    • Noel JP, Hamm HE, Sigler PB (1993) The 2.2 Å crystal structure of transducin-α complexed with GTPγS. Nature 366:654-663
    • (1993) Nature , vol.366 , pp. 654-663
    • Noel, J.P.1    Hamm, H.E.2    Sigler, P.B.3
  • 54
    • 0025759030 scopus 로고
    • s mutant is rescued by secondary mutation of the α chain amino terminus
    • s mutant is rescued by secondary mutation of the α chain amino terminus. J Biol Chem 266:4673-4676
    • (1991) J Biol Chem , vol.266 , pp. 4673-4676
    • Osawa, S.1    Johnson, G.L.2
  • 55
    • 0025310575 scopus 로고
    • Refined crystal structure of the triphosphate conformation of H-ras at 1.35 Å resolution: Implications for the mechanism of GTP hydrolysis
    • Pai EF, Krengel U, Petsko GA, Goody RS, Kabsch W, Wittinghofer A (1990) Refined crystal structure of the triphosphate conformation of H-ras at 1.35 Å resolution: implications for the mechanism of GTP hydrolysis. EMBO J 9:2351-2359
    • (1990) EMBO J , vol.9 , pp. 2351-2359
    • Pai, E.F.1    Krengel, U.2    Petsko, G.A.3    Goody, R.S.4    Kabsch, W.5    Wittinghofer, A.6
  • 56
    • 0028046412 scopus 로고
    • Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade
    • Printen JA, Sprague GF. (1994) Protein-protein interactions in the yeast pheromone response pathway: Ste5p interacts with all members of the MAP kinase cascade. Genetics 138:609-619
    • (1994) Genetics , vol.138 , pp. 609-619
    • Printen, J.A.1    Sprague, G.F.2
  • 57
    • 0026596419 scopus 로고
    • X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis
    • Privé GG, Milburn MV, Tong L, deVos AM, Yamaizumi Z, Nishimura S, Kim S-H (1992) X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis. Proc Natl Acad Sci USA 89:3649-3653
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3649-3653
    • Privé, G.G.1    Milburn, M.V.2    Tong, L.3    DeVos, A.M.4    Yamaizumi, Z.5    Nishimura, S.6    Kim, S.-H.7
  • 59
    • 0000848663 scopus 로고    scopus 로고
    • Yeast vector and assays for expression of cloned genes
    • Ausubel FA, Brent R, Kingston RE, Moore DM, Seidman JE, Smith JA, Struhl K (eds) John Wiley and Sons, New York
    • Reynolds A, Lundblad V, Dorris D, Keaveney M (1997) Yeast vector and assays for expression of cloned genes. In: Ausubel FA, Brent R, Kingston RE, Moore DM, Seidman JE, Smith JA, Struhl K (eds) Current protocols in molecular biology. John Wiley and Sons, New York, pp 13.6.1-13.6.6
    • (1997) Current Protocols in Molecular Biology , pp. 1361-1366
    • Reynolds, A.1    Lundblad, V.2    Dorris, D.3    Keaveney, M.4
  • 60
    • 0023464708 scopus 로고
    • Vectors for selective expression of cloned DNAs by T7 RNA polymerase
    • Rosenberg AH, Lade BN, Chui D-S, Lin SW (1987) Vectors for selective expression of cloned DNAs by T7 RNA polymerase. Gene 56:125-135
    • (1987) Gene , vol.56 , pp. 125-135
    • Rosenberg, A.H.1    Lade, B.N.2    Chui, D.-S.3    Lin, S.W.4
  • 62
    • 0025971103 scopus 로고
    • Assay of yeast mating reaction
    • Sprague GF (1991) Assay of yeast mating reaction. Methods Enzymol 194:77-93
    • (1991) Methods Enzymol , vol.194 , pp. 77-93
    • Sprague, G.F.1
  • 63
    • 0001134626 scopus 로고
    • Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae
    • Jones EW, Pringle JR, Broach JR (eds) Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Sprague GF, Thorner J (1992) Pheromone response and signal transduction during the mating process of Saccharomyces cerevisiae. In: Jones EW, Pringle JR, Broach JR (eds) The Molecular and cellular biology of the yeast Saccharomyces (vol 2). Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp 657-744
    • (1992) The Molecular and Cellular Biology of the Yeast Saccharomyces , vol.2 , pp. 657-744
    • Sprague, G.F.1    Thorner, J.2
  • 64
    • 0025937311 scopus 로고
    • N-myristoylation is required for function of the pheromone-responsive Gα protein of yeast: Conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase
    • Stone DE, Cole GM, de Barros Lopes M, Goebl M. Reed SI (1991) N-myristoylation is required for function of the pheromone-responsive Gα protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase. Genes Dev 5:1969-1981
    • (1991) Genes Dev , vol.5 , pp. 1969-1981
    • Stone, D.E.1    Cole, G.M.2    De Barros Lopes, M.3    Goebl, M.4    Reed, S.I.5
  • 68
    • 0023376280 scopus 로고
    • Two genes required for cell fusion during yeast conjugation: Evidence for a pheromone-induced surface protein
    • Trueheart J, Boeke JD, Fink GR (1987) Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol Cell Biol 7:2316-2328
    • (1987) Mol Cell Biol , vol.7 , pp. 2316-2328
    • Trueheart, J.1    Boeke, J.D.2    Fink, G.R.3
  • 71
    • 0024087042 scopus 로고
    • Expression of MFα1 in MATa cells supersensitive to α-factor leads to self-arrest
    • Whiteway MS, Hougan L, Thomas DY (1988) Expression of MFα1 in MATa cells supersensitive to α-factor leads to self-arrest. Molec Gen Genet 214:85-88
    • (1988) Molec Gen Genet , vol.214 , pp. 85-88
    • Whiteway, M.S.1    Hougan, L.2    Thomas, D.Y.3
  • 72
  • 75
    • 0030751510 scopus 로고    scopus 로고
    • Val50 mutant occurs through the default mating pathway and a suggestion of a role for ubiquitin-mediated proteolysis
    • Val50 mutant occurs through the default mating pathway and a suggestion of a role for ubiquitin-mediated proteolysis. Mol Biol Cell 8:1649-1664
    • (1997) Mol Biol Cell , vol.8 , pp. 1649-1664
    • Xu, B.-E.1    Kurjan, J.2


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