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Volumn 50, Issue 3, 1998, Pages 275-278

Pharmacokinetic assessment of the sites of first-pass metabolism of BMS-181101, an antidepressant agent, in rats

Author keywords

[No Author keywords available]

Indexed keywords

5 FLUORO 3 [3 [4 (5 METHOXY 4 PYRIMIDINYL) 1 PIPERAZINYL]PROPYL] 1H INDOLE; ANTIDEPRESSANT AGENT;

EID: 0031940567     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1998.tb06860.x     Document Type: Article
Times cited : (4)

References (17)
  • 1
    • 0030002504 scopus 로고    scopus 로고
    • Intestinal drug metabolism and anti-transport processes: A potential paradigm shift in oral drug delivery
    • Benet, L. Z., Wu, C.-Y., Hebert, M. F., Wacher, V. J. (1996) Intestinal drug metabolism and anti-transport processes: a potential paradigm shift in oral drug delivery. J. Contr. Rel. 39: 139-143
    • (1996) J. Contr. Rel. , vol.39 , pp. 139-143
    • Benet, L.Z.1    Wu, C.-Y.2    Hebert, M.F.3    Wacher, V.J.4
  • 2
    • 0019828356 scopus 로고
    • The systemic bioavailability of buprenorphine by various routes of administration
    • Brewster, D., Humphrey, M. J., McLeavy, M. A. (1981) The systemic bioavailability of buprenorphine by various routes of administration. J. Pharm. Pharmacol. 33: 500-506
    • (1981) J. Pharm. Pharmacol. , vol.33 , pp. 500-506
    • Brewster, D.1    Humphrey, M.J.2    McLeavy, M.A.3
  • 3
    • 0018903748 scopus 로고
    • In vivo assessment of extrahepatic conjugative metabolism of first-pass effects using the model compound phenol
    • Cassidy, M. K., Houston, J. B. (1980) In vivo assessment of extrahepatic conjugative metabolism of first-pass effects using the model compound phenol. J. Pharm. Pharmacol. 32: 57-59
    • (1980) J. Pharm. Pharmacol. , vol.32 , pp. 57-59
    • Cassidy, M.K.1    Houston, J.B.2
  • 4
    • 0026023416 scopus 로고
    • Pharmacokinetics of butixocort 21-propionate, budesonide, and beclomethasone dipropionate in the rat after intratracheal, intravenous and oral treatments
    • Chanoine, F., Grenot, C., Heidmann, P., Junien, J. L. (1991) Pharmacokinetics of butixocort 21-propionate, budesonide, and beclomethasone dipropionate in the rat after intratracheal, intravenous and oral treatments. Drug Metab. Dispos. 19: 546-553
    • (1991) Drug Metab. Dispos. , vol.19 , pp. 546-553
    • Chanoine, F.1    Grenot, C.2    Heidmann, P.3    Junien, J.L.4
  • 5
    • 0015691676 scopus 로고
    • The effect of route of administration on the metabolic fate of terbutaline in the rat
    • Conway, W. D., Singhvi, S. M., Gibaldi, M., Boyes, R. N. (1973) The effect of route of administration on the metabolic fate of terbutaline in the rat. Xenobiotica 3: 813-821
    • (1973) Xenobiotica , vol.3 , pp. 813-821
    • Conway, W.D.1    Singhvi, S.M.2    Gibaldi, M.3    Boyes, R.N.4
  • 7
    • 0025057187 scopus 로고
    • Metabolism of drugs and other xenobiotics in the gut lumen and wall
    • Ilett, K. F., Tee, L. B. G., Reeves, P. T., Minchin, R. F. (1990) Metabolism of drugs and other xenobiotics in the gut lumen and wall. Pharmacol. Ther. 46: 67-93
    • (1990) Pharmacol. Ther. , vol.46 , pp. 67-93
    • Ilett, K.F.1    Tee, L.B.G.2    Reeves, P.T.3    Minchin, R.F.4
  • 10
    • 0025719746 scopus 로고
    • First-pass metabolism of cyclosporin by gut
    • Kolars, J. C., Awni, W. M., Merion, R. M., Watkins, P. B. (1991) First-pass metabolism of cyclosporin by gut. Lancet 338: 1488-1490
    • (1991) Lancet , vol.338 , pp. 1488-1490
    • Kolars, J.C.1    Awni, W.M.2    Merion, R.M.3    Watkins, P.B.4
  • 11
    • 0025734921 scopus 로고
    • Sites of first-pass bioactivation (hydrolysis) of orally administered zofenopril calcium in dogs
    • Morrison, R. A., Burkett, D. E., Arnold, M. E., D'Arienzo, C. J., Weinstein, S. H. (1991) Sites of first-pass bioactivation (hydrolysis) of orally administered zofenopril calcium in dogs. Pharm. Res. 8: 370-375
    • (1991) Pharm. Res. , vol.8 , pp. 370-375
    • Morrison, R.A.1    Burkett, D.E.2    Arnold, M.E.3    D'Arienzo, C.J.4    Weinstein, S.H.5
  • 12
    • 0019274427 scopus 로고
    • The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time
    • Riegelman, S., Collier, P. (1980) The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time. J. Pharmacokin. Biopharm. 8: 509-534
    • (1980) J. Pharmacokin. Biopharm. , vol.8 , pp. 509-534
    • Riegelman, S.1    Collier, P.2
  • 13
    • 0029885898 scopus 로고    scopus 로고
    • High-performance liquid chromatographic-ultraviolet assay for the simultaneous determination of BMS-181101 and its putative hydroxy metabolites in rat and monkey plasma
    • Shah, V. R., Srinivas, N. R., Campbell, D. A., Mantha, S., Duncan, G., Schuster, A., Whigan, D. B., Shyu, W. C. (1996) High-performance liquid chromatographic-ultraviolet assay for the simultaneous determination of BMS-181101 and its putative hydroxy metabolites in rat and monkey plasma. Biomed. Chromatogr. 10: 135-138
    • (1996) Biomed. Chromatogr. , vol.10 , pp. 135-138
    • Shah, V.R.1    Srinivas, N.R.2    Campbell, D.A.3    Mantha, S.4    Duncan, G.5    Schuster, A.6    Whigan, D.B.7    Shyu, W.C.8
  • 15
    • 0029028792 scopus 로고
    • Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and p-glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
    • Wacher, V. J., Wu, C-Y., Benet, L. Z. (1995) Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and p-glycoprotein: implications for drug delivery and activity in cancer chemotherapy. Mol. Carcinogenesis 13: 129-134
    • (1995) Mol. Carcinogenesis , vol.13 , pp. 129-134
    • Wacher, V.J.1    Wu, C.-Y.2    Benet, L.Z.3
  • 16
    • 0023588109 scopus 로고
    • Identification of glucocorticoid-inducible cytochrome P-450 in the intestinal mucosa of rats and man
    • Watkins, P. B., Wrighton, S. A., Schuetz, E. G., Molowa, D. T., Guzelian, P. S. (1987) Identification of glucocorticoid-inducible cytochrome P-450 in the intestinal mucosa of rats and man. J. Clin. Invest. 80: 1029-1036
    • (1987) J. Clin. Invest. , vol.80 , pp. 1029-1036
    • Watkins, P.B.1    Wrighton, S.A.2    Schuetz, E.G.3    Molowa, D.T.4    Guzelian, P.S.5
  • 17
    • 0027949097 scopus 로고
    • First-pass effect of cis-3,4-dichloro-N-rnethyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzamide (U-54494) in rats - A model with multiple cannulas for investigation of gastrointestinal and hepatic metabolism
    • Zhong, W.-Z., Williams, M. G., Cook, K. J., VandeGiessen, T. L., Jones, B. W., Rousch, K. E. (1994) First-pass effect of cis-3,4-dichloro-N-rnethyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzamide (U-54494) in rats - a model with multiple cannulas for investigation of gastrointestinal and hepatic metabolism. Pharm. Res. 11: 1524-1529
    • (1994) Pharm. Res. , vol.11 , pp. 1524-1529
    • Zhong, W.-Z.1    Williams, M.G.2    Cook, K.J.3    VandeGiessen, T.L.4    Jones, B.W.5    Rousch, K.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.