Three-dimensional matrix primes mesangial cells to down-regulation of α-smooth muscle actin via deactivation of CArG box elements

Kidney International

Volumn 53, Issue 3, 1998, Pages 690-697

  Kitamura, Masanori ^a   Ishikawa, Yoshihisa ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

CArG box element; Extracellular matrix; Mesangial cell; Serum response element; smooth muscle actin

Indexed keywords

ALPHA ACTIN; BETA GALACTOSIDASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; MALE; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INDUCTION; RAT; SMOOTH MUSCLE;

EID: 0031940490     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1998.00806.x     Document Type: Article

References (49)

1. KITAMURA M, MITARAI T, MARUYAMA N, NAGASAWA R, YOSHIDA H, SAKAI O: Mesangial cell behavior in a three-dimensional extracellular matrix. Kidney Int 40:653-661, 1991
2. KITAMURA M, SHIRASAWA T, MARUYAMA N: Gene transfer of metalloproteinase transin induces aberrant behavior of cultured mesangial cells. Kidney Int 45:1580-1586, 1994
3. KITAMURA M, MITARAI T, NAGASAWA R, MARUYAMA N: Differentiated phenotype of glomerular mesangial cells in nodular culture. Am J Physiol 270:F614-F622, 1996
4. STERZEL RB, LOVETT DH, FOELLMER HG, PERFETTO M, BIEMESDERFER D, KASHGARIAN M: Mesangial cell hillocks. Nodular foci of exaggerated growth of cells and matrix in prolonged culture. Am J Pathol 125:130-140, 1986
5. JOHNSON RJ, FLOEGE J, YOSHIMURA A, IIDA H, COUSER WG, ALPERS CE: The activated mesangial cell: A glomerular "myofibroblast"? J Am Soc Nephrol 2(Suppl):S190-S197, 1992
6. ALPERS CE, HUDKINS KL, GOWN AM, JOHNSON RJ: Enhanced expression of "muscle-specific" actin in glomerulonephritis. Kidney Int 41:1134-1142, 1992
7. ELGER M, DRENCKHAHN D, NOBILING R, MUNDEL P, KRIZ W: Cultured rat mesangial cells contain smooth muscle α-actin not found in vivo. Am J Pathol 142:497-509, 1993
8. JOHNSON RJ, IIDA H, ALPERS CE, MAJESKY MW, SCHWARTZ SM, PRITZL P, GORDON K, GOWN AM: Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis: α-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest 87:847-858, 1991
9. MACPHERSON BR, LESLIE KO, LIZASO KV, SCHWARZ JE: Contractile cells of the kidney in primary glomerular disorders: An immunohistochemical study using an anti-alpha smooth muscle actin monoclonal antibody. Hum Pathol 24:710-716, 1993
10. FLOEGE J, JOHNSON RJ, GORDON K, IIDA H, PRITZL P, YOSHIMURA A, CAMPBELL C, ALPERS CE, COUSER WG: Increased synthesis of extracellular matrix in mesangial proliferative nephritis. Kidney Int 40:477-488, 1991
11. KIMURA K, HIROI J, TOJO A, SUZUKI N, OHBA S, MISE N, OMATA M, NAGAI R: Multiplicity of phenotypic modulation in glomerular cells during development of different glomerular diseases. (abstract) J Am Soc Nephrol 6:871, 1995
12. BLANK RS, MCQUINN TC, YIN KC, THOMPSON MM, TAKEYASU K, SCHWARTZ RJ, OWENS GK: Elements of the smooth muscle α-actin promoter required in cis for transcriptional activation in smooth muscle. J Biol Chem 267:984-989, 1992
13. KIM J-H, BUSHEL PR, KUMAR CC: Smooth muscle α-actin promoter activity is induced by serum stimulation of fibroblast cells. Biochem Biophys Res Commun 190:1115-1121, 1993
14. MIN B, FOSTER DN, STRAUCH AR: The 5′-flanking region of the mouse vascular smooth muscle α-actin gene contains evolutionarily conserved sequence motifs within a functional promoter. J Biol Chem 265:16667-16675, 1990
15. TREISMAN R: The serum response element. Trends Biochem Sci 17:423-426, 1992
16. SIMONSON MS, WALSH K, KUMAR CC, BUSHEL P, HERMAN WH: Two proximal CArG elements regulate SM α-actin promoter, a genetic marker of activated phenotype of mesangial cells. Am J Physiol 268:F760-F769, 1995
17. KITAMURA M, TAYLOR S, UNWIN R, BURTON S, SHIMIZU F, FINE LG: Gene transfer into the rat renal glomerulus via a mesangial cell vector: Site-specific delivery, in situ amplification and sustained expression of an exogenous gene in vivo. J Clin Invest 94:497-505, 1994
18. KITAMURA M, BURTON S, ENGLISH J, KAWACHI H, FINE LG: Transfer of a mutated gene encoding active transforming growth factor-β1 suppresses mitogenesis and IL-1 response in the glomerulus. Kidney Int 48:1747-1757, 1995
19. MEINKOTH J, ALBERTS A, FERAMISCO J: Construction of mammalian cell lines with indicator genes driven by regulated promoters. CIBA Foundation Symp 150:47-56, 1990
20. KITAMURA M: Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus. Proc Natl Acad Sci USA 93:7387-7391, 1996
21. KITAMURA M, KAWACHI H: Creation of an in vivo cytosensor using engineered mesangial cells: Automatic sensing of glomerular inflammation controls transgene activity. J Clin Invest 100:1394-1399, 1997
22. KLUNDER I, HULSER DF: β-Galactosidase activity in transfected Ltk-cells is differentially regulated in monolayer and in spheroid cultures. Exp Cell Res 207:155-162, 1993
23. KIM J-H, JOHANSEN F-E, ROBERTSON N, CATINO JJ, ORYWES R, KUMAR CC: Suppression of Ras transformation by serum response factor. J Biol Chem 269:13740-13743, 1994
24. YOKOO T, KITAMURA M: Dual regulation of IL-1β-mediated matrix metalloproteinase-9 expression in mesangial cells by NF-κB and AP-1. Am J Physiol 270:F123-F130, 1996
25. MIKAWA T, FISCHMAN DA, DOUGHERTY JP, BROWN AMC: In vivo analysis of a new lacZ retrovirus vector suitable for cell lineage marking in avian and other species. Exp Cell Res 195:516-523, 1991
26. WHITMARSH AJ, SHORE P, SHARROCKS AD, DAVIS RJ: Integration of MAP kinase signal transduction pathways at the serum response element. Science 269:403-407, 1995
27. KITAMURA M, ISHIKAWA Y: Functional inactivation of signalling molecules via transdominant negative mutants. Exp Nephrol 5:435-438, 1997
28. KUMAR CC, BUSHEL P, MOHAN-PETERSON S, RAMIREZ F: Regulation of smooth muscle α-actin promoter in ras-transformed cells: Usefulness for setting up reporter gene-based assay system for drug screening. Cancer Res 52:6877-6884, 1992
29. ARGENTON F, ARAVA Y, ARONHEIM A, WALKER MD: An activation domain of the helix-loop-helix transcription factor E2A shows cell type preference in vivo in microinjected Zebra Fish embryo. Mol Cell Biol 16:1714-1721, 1996
30. KITAMURA M, MARUYAMA N, YOSHIDA H, NAGASAWA R, MITARAI T, SAKAI O: Extracellular matrix contraction by cultured mesangial cells: An assay system for mesangial cell-matrix interaction. Exp Mol Pathol 54:181-200, 1991
31. KITAMURA M, SÜTÖ T, YOKOO T, SHIMIZU F, FINE LG: Transforming growth factor-β1 is the predominant paracrine inhibitor of macrophage cytokine synthesis produced by glomerular mesangial cells. J Immunol 156:2964-2971, 1996
32. MCHUGH KM, LESSARD JL: The nucleotide sequence of a rat vascular smooth muscle α-actin cDNA. Nucleic Acids Res 16:4167, 1988
33. PRICE J, TURNER D, CEPKO C: Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer. Proc Natl Acad Sci USA 84:156-160, 1987
34. TREISMAN R: The SRE: A growth factor responsive transcriptional regulator. Semin Cancer Biol 1:47-58, 1990
35. GABBIANI G: The biology of the myofibroblast. Kidney Int 41:530-532, 1992
36. ANDRAWIS NS, RULEY EH, ABERNETHY DR: Angiotensin II regulates human vascular smooth muscle α-actin gene expression. Biochem Biophys Res Commun 196:962-968, 1993
37. HAHN AW, RESINK TJ, KERN F, BUHLER FR: Effects of endothelin-1 on vascular smooth muscle cell phenotypic differentiation. J Cardiovasc Pharmacol 20:S33-S36, 1992
38. VAN PUTTEN V, LI X, MASELLI J, NEMENOFF RA: Regulation of smooth muscle actin promoter by vasopressin and platelet-derived growth factor in rat aortic vascular smooth muscle cells. Circ Res 75:1126-1130, 1994
39. ARCINIEGAS E, SUTTON AB, ALLEN TD, SCHOR AM: Transforming growth factor beta-1 promotes the differentiation of endothelial cells into smooth muscle-like cells in vitro. J Cell Sci 103:521-529, 1992
40. RUBBIA-BRANDT L, SAPPINO A-P, GABBIANI G: Locally applied GM-CSF induces the accumulation of α-smooth muscle actin containing myofibroblasts. Virchows Archiv B Cell Pathol 60:73-82, 1991
41. HANSSON GK, HELLSTRAND M, RYMO L, RUBBIA L, GABBIANI G: Interferon γ inhibits both proliferation and expression of differentiation-specific α-smooth muscle actin in arterial smooth muscle cells. J Exp Med 170:1595-1608, 1989
42. JULIANO RL, HASKILL S: Signal transduction from the extracellular matrix. J Cell Biol 120:577-585, 1993
43. MARX M, DANIEL TO, KASHGARIAN M, MADRI JA: Spatial organization of the extracellular matrix modulates the expression of PDGF-receptor subunits in mesangial cells. Kidney Int 43:1027-1041, 1993
44. RUPPRECHT HD, SUKHATME VP, LACY J, STERZEL RB, COLEMAN DL: PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements. Am J Physiol 265:F351-F360, 1993
45. FAK, a structurally distinctive protein-tyrosine kinase associated with focal adhesion. Proc Natl Acad Sci USA 89:5192-5196, 1992
46. HANKS SK, POLTE TR: Signaling through focal adhesion kinase. BioEssay 19:137-145, 1997
47. ISHIKAWA Y, KITAMURA M: Unpredicted suppression of the ERK-Elk1-SRE pathway by v-Src tyrosine kinase in cultured mesangial cells. (abstract) J Am Soc Nephrol 8:440A, 1997
48. JOHNSON RJ, FLOEGE J, COUSER WG, ALPERS CE: Role of platelet-derived growth factor in glomerular disease. J Am Soc Nephrol 4:119-128, 1993
49. HOFER G, GRIMMER C, SUKHATME VP, STERZEL RB, RUPPRECHT HD: Transcription factor Egr-1 regulates glomerular mesangial cell proliferation. J Biol Chem 271:28306-28310, 1996