Endothelins - Vasoactive peptides and growth factors

Cell and Tissue Research

Volumn 292, Issue 1, 1998, Pages 1-9

  Stjernquist, Martin ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Blood vessels; Endothelin; Endothelium; Hypertension; Preeclampsia

Indexed keywords

ENDOTHELIN; ENDOTHELIN RECEPTOR; GROWTH FACTOR;

BRAIN ISCHEMIA; FETUS DEVELOPMENT; HYPERTENSION; ISCHEMIC HEART DISEASE; PATHOPHYSIOLOGY; PREECLAMPSIA; PRIORITY JOURNAL; REVIEW; SUBARACHNOID HEMORRHAGE; VASCULAR DISEASE;

AMINO ACID SEQUENCE; ANIMALS; ENDOTHELINS; GROWTH SUBSTANCES; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES; VASOCONSTRICTION;

EID: 0031940161     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410051028     Document Type: Review

References (104)

1. Arai H, Hori S, Aramori I, Ohkuhi H, Nakanishi S (1990) Cloning and expression of a cDNA coding an endothelin receptor. Nature 348:730
2. Baley PA, Resink TJ, Eppenberger U, Hahn AW (1990) Endothelin messenger RNA and receptors are differently expressed in cultured human breast epithelial and stromal cells. J Clin Invest 85:1320-1323
3. Barone FC, White RF, Elliot JD, Feurstein GZ, Ohlstein EH (1995) The endothelin receptor antagonist SB 217242 reduces cerebral focal ischemic brain injury. J Cardiovasc Pharmacol 26 [Suppl 3]:S404-S407
4. Battistini B, Botting R, Warner TD (1995) Endothelin: a knock out in London. Trends Pharmacol Sci 16:217-222
5. Bax WA, Saxena PR (1994) The current endothelin receptor classification: time for reconsideration? Trends Pharmacol Sci 15: 379-386
6. Baynash AG, Hosoda K, Giaid A, Richardson JA, Emoto N, Hammer RE (1994) Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons. Cell 79:1277-1285
7. Benigni A, Gaspari F, Orisio S, Bellizi L, Amuso G, Frusca T, Remuzzi G (1991) Human placenta expresses endothelin gene and corresponding protein is excreted in urine in increasing amounts during normal pregnancy. Am J Obstet Gynecol 164:844-848
8. Bird JE, Moreland S, Waldron TL, Powell JR (1995) Antihypertensive effects of a novel endothelin-A receptor antagonist in rats. Hypertension 25:1191-1195
9. 125I-endothelin-1 binding sites in human umbilical artery. Eur J Pharmacol 249:299-305
10. Bodelsson G, Sjöberg N, Stjernquist M (1992) Contractile effect of endothelin in the human uterine artery and autoradiographic localization of its binding sites. Am J Obstet Gynecol 167:745-750
11. Bodelsson G, Marsal K, Stjernquist M (1995) Reduced contractile effect of endothelin-1 and noradrenalin in human umbilical artery from pregnancies with abnormal umbilical artery flow velocity waveforms. Early Hum Dev 42:15-28
12. Bodelsson G, Laursen M, Stjernquist M (1996) Oxygen promotes contraction by endothelin-1 in human umbilical artery. Hum Reprod 11:2767-2768
13. Cameron IT, Bacon CR, Collett GP, Davenport AP (1995) Endothelin expression in the uterus. J Steroid Biochem Mol Biol 53: 209-214
14. Casasco A, Calligaro A, Casasco M, Springall DR, Tenti P, Marchetti P, Poggi P, Polak JM (1991) Immunohistochemical localization of endothelin-like immunoreactivity in human tooth germe and mature dental pulp. Anat Embryol 183:515-520
15. Casey ML, Word RA, MacDonald PC (1991) Endothelin 1 expression and regulation of endothelin mRNA and protein biosynthesis in avascular human amnion. Potential source of amniotic flu id endothelin. J Biol Chem 266:5762-5768
16. Clozel J-P, Clozel M (1989) Effects of endothelin on the coronary vascular bed in open chest dogs. Circ Res 65:1193-1200
17. Clozel M, Breu V, Burri K, Cassai JM, Fishli W, Gray GA, Hirth G, Loffler B, Muller M, Neidhart W, Ramuz H (1993) Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature 365:759-761
18. Douglas SA, Louden L, Vickery-Clark LM (1994) A role for endogenous endothelin-1 in intimal formation after rat carotid artery balloon angioplasty. Cardiovasc Res 75:190-197
19. Economos K, MacDonald PC, Casey ML (1992) Endothelin 1 gene expression and protein biosynthesis in human endometrium: potential modulator of endometrial blood flow. J Clin Endocrinol Metab 74:14-19
20. Eddahibi S, Raffestin B, Clozel M, Levame M, Adnot S (1995) Protection from pulmonary hypertension with an orally active endothelin receptor antagonist in hypoxic rats. Am J Physiol 268: H828-H835
21. Eguchi S, Hirata Y, Imai T, Kanno K, Akiba T, Sakamoto A, Yanagisawa M, Masaki T, Marumo F (1992) Endothelin receptors in human parathyroid gland. Biochem Biophys Res Commun 184:1448-1455
22. Ehrenreich H, Andersson RW, Fox CH, Rieckman P, Hoffman GS, Travis WD, Coligan JE, Kehrl JH, Fauci AS (1990) Endothelins, peptides with potent vasoactive properties are produced by macrophages. J Exp Med 172:1741-1748
23. Ehrenreich H, Lange M, Near KA, Anneser F, Schmid R, Schoeller LAC (1992) Long term monitoring of immunoreactive endothelin-1 and endothelin-3 in ventricular cerebrospinal fluid, plasma, and 24-h urine of patients with subarachnoid hemorrhage. Res Exp Med 192:257-268
24. Furchgott RF, Zawadzki JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373-376
25. Giaid A, Gibson SJ, Herrero MT, Gentleman S, Legon S, Yanagisawa M, Masaki T, Ibrahim NB, Roberts GW, Rossi ML (1991) Topographical localization of endothelin mRNA and peptide immunoreactivity in neurons of the human brain. Histochemistry 95:303-314
26. Greer IA, Leask R, Hodson BA, Dawes J, KIlpatrick DC, Liston WA (1991) Endothelin, elasatse, and endothelial dysfunction in pre-eclampsia. Lancet 337:558
27. Grover GJ, Ezwonczyk S, Parham CS (1993) The endothelin-1 receptor antagonist BQ-123 reduces infarct size in a canine model of coronary occlusion and reperfusion. Cardiovasc Res 27: 1613-1618
28. Haegerstrand A, Hemsén A, Gillis C, Larsson O, Lundberg JM (1989) Endothelin: presence in human umbilical vessels, high levels in fetal blood and potent constrictor effect. Acta Physiol Scand 137:541-542
29. Haynes WG, Webb DJ (1994) Contribution of endogenous generation of endothelin-1 to vascular tone. Lancet 344:852-854
30. Haynes WG, Davenport AP, Webb DJ (1993) Endothelin: progress in pharmacology and physiology. Trends Pharmacol Sci 14:225-228
31. Hickey KA, Rubanyi GM, Paul RJ, Highsmith RF (1985) Characterization of a coronary vasoconstriction produced by cultured endothelial cells. Am J Physiol 248:C550-C556
32. Hiley CR (1995) Endothelin receptor ligands. Neurotransmissions 11:1-6
33. Hosoda K, Hammer RE, Richardson JA, Baynash AG, Cheung JC, Giaid A (1994) Targeted and neutral (Pibald-Lethal) mutations of endothelin-B receptor gene produces megacolon associated with spotted coat color in mice. Cell 79:1267-1276
34. A receptor. Life Sci 50:247
35. Inoue A, Yanagisawa M, Kimura S, Kasuya Y, Miyachi T, Goto K, Masaki T (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 86:2863-2867
36. Ishikawa T, Yanagisawa M, Kimura S, Goto K, Masaki T (1988) Positive inotropic action of novel vasoconstrictor peptide endothelin on guinea pig atria. Am J Physiol 255:H970-H973
37. Itoh Y, Yanagisawa M, Ohkubo S, Kimura C, Inoue A, Ishida N, Mitsui Y, Onda H, Fujino M, Masaki T (1988) Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin; identity of human and porcine endothelin. FEBS Lett 231:440-444
38. Kanazawa H, Kurihara N, Hirata K, Fujiwara H, Matsushita H, Takeda T (1992) Low concentration endothelin 1 enhanced histamine mediated bronchial contractions of guinea pigs in vivo. Biochem Biophys Res Commun 187:717-721
39. Kasuya Y, Dobayashi H, Uemura H (1991) Endothelin like immunoreactivity in the nervous system of invertebrates and fish. J Cardiovasc Pharmacol 17 [Suppl 7]:S463-S466
40. Keiji H (1991) Eur Patent Appl 457 195 A2
41. Kimura S, Kasuya Y, Sawamura T, Shinmi O, Sugita Y, Yanagisawa M, Goto K, Masaki T (1988) Structure-activity relationships of endothelin: importance of the C-terminal moiety. Biochem Biophys Res Commun 156:1182-1186
42. Kiowski W, Sütsch G, Hunziker P, Müller P, Kim J, Oeschlin E (1995) Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet 346:732-736
43. 2 accumulation in rat IMCD. Am J Physiol 265:670-676
44. Kurihara Y, Kurihara H, Suzuki H, Kodama T, Maemura K, Nagai R (1994) Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature 368:703-710
45. A receptor antagonist reduces myocardial infarction induced by coronary artery occlusion and reperfusion in the rat. Pharmacology 49:319-314
46. Lee ME, De la Monte SM, Ng SC, Bloch KD, Quertermous T (1990) Expression of the potent vasoconstrictor endothelin in the human central nervous system. J Clin Invest 86:141-147
47. Lerman A, Edwards BS, Hallett JW, Heublein DM, Sandberg SN, Burnett JC (1991) Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis. N Engl J Med 325:997-1001
48. Li XS, Wang QD, Pernow J (1995) Beneficial effects of the endothelin receptor antagonist bosentan on myocardial and endothelial injury following ischaemia/reperfusion in the rat. Eur J Pharmacol 283:161-168
49. Masaki T, Kimura S, Yanagisawa M, Goto K (1991) Molecular and cellular effects of endothelin regulation. Implications for vascular function. Circulation 84:1457-1468
50. Masaki T, Yanagisawa M, Goto K (1992) Physiology and pharmacology of endothelins. Med Res Rev 12:391-421
51. Matsumura Y, Ikegawa R, Suzuki Y, Takaoka M, Uchida T, Kido H, Shinyama H, Hayashi K, Watanabe M, Morimoto S (1991) Phosphoramidon prevents cerebral vasospasm following subarachnoidal hemorrhage in dogs: the relationship to endothelin 1 levels in the cerebrospinal fluid. Life Sci 49:841-848
52. Matsuyiama K, Yasue H, Okumura K, Saito Y, Nakao K, Shirakami G, Imura H (1991) Increased plasma level of endothelin 1 like immunoreactivity during coronary vasospasm in patients with coronary spastic angina. Am J Cardiol 68:991-995
53. Mattoli S, Soloperto M, Marini M, Fasoli A (1991) Levels of endothelin in the bronchoalveolar lavage fluid of patients with symptomatic asthma reversible airflow obstruction. J Allergy Clin Immunol 88:376-384
54. McMahon EG, Palomo MA, Moore WM (1991a) Phosphoramidon blocks the pressor activity of big endothelin [1-39] and lowers blood pressure in spontaneously hypertensive rats. J Cardiovasc Pharmacol 17 [Suppl 7]:S29-S33
55. McMahon EG, Palomo MA, Moore WM, McDonald JF, Stern MK (1991b) Phosphoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39) to endothelin-1-(1-21) in vitro. Proc Natl Acad Sci USA 88:703-707
56. A receptor-specific effect of 50-235, a nonpeptide endothelin antagonist. Eur J Pharmacol 246:33-38
57. Mitchell MD, Lundin-Schiller S, Edwin SS (1991) Endothelin production by amnion and its regulation by cytokines. Am J Obstet Gynecol 165:120-124
58. Miyauchi T, Yanagisawa M, Tomizawa T (1989) Increased plasma concentrations of endothelin-1 and big endothelin-1 in acute myocardial infarction. Lancet 2:53-54
59. Miyauchi T, Tomobe Y, Shiba R (1990) Involvement of endothelin in the regulation of human vascular tonus: potent vasoconstrictor effect and existence in endothelial cells. Circulation 81:1874-1880
60. Moncada S, Gryglewski R, Bunting S, Vane JR (1976) An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable sustance that inhibits platelet aggregation. Nature 263:663-665
61. B-like receptors. Biochem Biophys Res Commun 184:100
62. Neubauer S, Zimmerman S, Hirsch A, Pulzer F, Tian R, Bauer W, Bauer B, Ertl G (1991) Effects of endothelin 1 in the isolated heart in ischemia/reperfusion and hypoxia/reoxygenation injury. J Mol Cell Cardiol 23:1397-1409
63. Nisell H, Hemsén A, Lunell N, Wolff K, Lundberg J (1990) Maternal and fetal levels of a novel polypeptide, endothelin: evidence for release during pregnancy and delivery. Gynecol Obstet Invest 30:129
64. Nishikibe M, Tsuchida S, Okada M, Fukuoda T, Shimamoto K, Yano M, Ischikaa K, Ikemoto F (1993) Antihypertensive effect of a newly synthesized endothelin antagonist, BQ123, in a genetic hypertensive model. Life Sci 52:717-724
65. O'Reilly G, Charnock Jones DS, Davenport AP, Cameron IT, Smith SK (1992) Presence of messenger ribonueleic acid for endothelin 1, endothlin 2 and endothelin 3 in human endometrium and change in the ratio of ETA and ETB subtype across the menstrual cycle. J Clin Endocrinol Metab 75:1545-1549
66. Offermans S, Segulitz G (1994) Complex information processing by the transmembrane signalling system involving G-proteins. Naunyn Schimiedebergs Arch Pharmacol 350:329-338
67. Okada M, Yamashita C, Okada K (1995) Endothelin receptor antagonist in a beagle model of pulmonary hypertension: contribution to possible potential therapy? J Am Coll Cardiol 25:1213-1217
68. Oparil S, Chen SJ, Cheng Meng O, Elton TS, Yano M, Chen YF (1995) Endothelin - a receptor antagonist prevents acute hypoxia-induced pulmonary hypertension in the rat. Am J Physiol 268:L95-L100
69. Opgenorth TJ, Wu-Wong JR, Shiosaki K (1992) Endothelin-converting enzymes. FASEB J 6:2653-2659
70. Palmer RMJ, Ferrige AG, Moncada S (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526
71. Patel TR, Galbraith SL, McAuley MA, Doherty AM, Graham DI, McCulloch J (1995) Therapeutic potential of endothelin receptor antagonist in experimental stroke. J Cardiovasc Pharmacol 26 [Suppl 3]:S404-S415
72. Randall M (1994) Endothelins: from laboratory to clinic? Lancet 344:832-833
73. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK (1989) Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 161:1200-1204
74. Rubanyi GM (1989) Maintenance of "basal" vascular tone may represent a physiological role for endothelin. J Vasc Med Biol 1:315-316
75. Rubanyi GM, Polokoff MA (1994) Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 46:325-415
76. Rubanyi GM, Shepherd JT (1992) Hypothetical role of endothelin in the control of the cardiovascular system. In: Rubanyi GM (ed) Endothelin. Oxford University Press, Oxford, pp 258-271
77. B agonistic activity. Biochem Biophys Res Commun 179:286-292
78. Saenz de Tejada I, Carson MP, De las Morenas A, Goldstein I, Traish AM (1991) Endothelin: localization, synthesis, activity, and receptor types in human penile corpus cavernosum. Am J Physiol 261:H1078-H1085
79. Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, Masaki T (1990) Cloning of a cDNA encoding a non-isopeptide selective subtype of the endothelin receptor. Nature 348:732
80. Schiff E, Galron R, Ben-Baruch G, Mashiach S, Sokolovsky M (1993) Endothelin-1 receptors on the human placenta and fetal membrnnes: evidence for different binding properties in preeclamptic pregnancies. Gynecol Endocrinol 35:67-72
81. Schiffrin E (1995) Endothelin: potential role in hypertension and vascular hypertrophy. Hypertension 25:1135-1143
82. Shichiri M, Hirata Y, Nakajima T, Ando K, Imai T, Yanagisawa M, Masaki T, Marumo F (1991) Endothelin 1 is an autocrine/paracrine growth factor for human cancer cell lines. J Clin Invest 87:1867-1871
83. Shigeno T, Clozel M, Sakai S, Saito AS, Goto K (1995) The effect of bosentan, a new potent endothelin receptor antagonist, on the pathogenesis of cerebral vasospasm. Neurosurgery 37:87-91
84. Stewart DJ, Levy RD, Cernacek P, Langleben D (1991) Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? Ann Intern Med 114:464-169
85. Suzuki R, Masoaka H, Hirata Y, Marumo F, Isotani E, Hirakawa K (1992) The role of endothelin 1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid haemorrhage. J Neurosurg 77:96-100
86. Taylor RN, Varma M, Teng NNH, Roberts JM (1990) Women with preeclampsia have higher plasma endothelin levels than women with normal pregnancies. Endocrinol Metab 71:1675-1677
87. Tokunaga O, Fan J, Watanabe T, Kobayashi M, Kumazaki T, Mitsui Y (1992) Endothelin. Immunohistological localization in aorta and biosynthesis by cultured human aortic endothelial cells. Lab Invest 67:210-217
88. Tönnessen T, Giaid A, Saleh D, Naess PA, Yanagisawa M, Christensen G (1995) Increased in vivo expression and production of endothelin-1 by porcine cardiomyocytes subjected to ischemia. Circ Res 76:767-772
89. Wang QD, Hemsén A, Li XS, Lundberg JM, Urida Y, Pernow J (1995a) Local overflow and enhanced tissue content of endothelin following myocardial ischaemia and reperfusion in the pig: modulation by L-arginine. Cardiovasc Res 29:44-49
90. Wang QD, Li XS, Lundberg JM, Pernow J (1995b) Protective effects of non-peptide endothelin receptor antagonist bosentan on myocardial ischaemic and reperfusion injury in the pig. Cardiovasc Res 29:805-812
91. Warner TD, Elliot JD, Ohlstein EH (1996) California dreamin' 'bout endothelin: emerging new therapeutics. Trends Pharmacol Sci 17:177-181
92. Watanabe T, Kusumoto K, Kitayoshi T, Shimamoto N (1989) Positive inotropic and vasoconstrictive effects of endothelin 1 in in vivo and in vitro experiments: characteristics and the role of L type calcium channels. J Cardiovasc Pharmacol 13 [Suppl 5]:S108-S111
93. B receptor antagonist, TAK-044 and the inhibition of myocardial infarct size in rats. Br J Pharmacol 114:949-954
94. Weitzberg E, Hémsen A, Rudehill A, Modin A, Wanecek M, Lundberg JM (1996) Bosentan improves cardiopulmonary vascular performance and increases plasma levels of endothelin-1 in porcine endotoxin shock. Br J Pharmacol 118:617-626
95. Widimsky JJ, Horky K, Dvorakova J (1991) Plasma endothelin 1,2 levels in mild and severe hypertension. J Hypertens [Suppl] 9:S194-S195
96. Wolff K, Carlström K, Kublickiene K, Hemsén A, Lunell N-O, Nisell H, Lindblom B (1996a) Endothelin-1 and big endothelin-1 levels in normal term pregnancy and in preeclampsia. Regul Pept 67:211-216
97. Wolff K, Faxén M, Lunell N-O, Nisell H, Lindblom B (1996b) Endothelin receptor type A and B gene expression in human non-pregnant, term pregnant and preeclamptic uterus. Am J Obstet Gynecol 175:1295-1300
98. A receptor antagonist BQ-123 on resistance arteries from normal pregnant and preeclamptic women. Acta Obstet Gynecol Scand 75:432-438
99. Yanagisawa M (1994) The endothelin system. A new target for therapeutic intervention. Circulation 89:1320-1322
100. Yanagisawa M, Masaki T (1989) Endothelin, a novel endothelium-derived peptide, regulation and possible roles in cardiovascular control. Biochem Pharmacol 12:1877-1883
101. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415
102. Yohn JJ, Morelli JG, Walchac SJ, Rundell KB, Norris DA, Zamora MR (1993) Cultured human keratinocytes synthesize and secrete endothelin 1. J Invest Dermatol 100:23-26
103. Zeiher AM, Goebel H, Sehächinger V, Ihling C (1995) Tissue endothelin-1 immunoreactivity in the active coronary atherosclerotic plaque. Circulation 91:941-947
104. Ziv I, Fleminger G, Djaldetti R, Achiron A, Melamed E, Sokolovsky M (1992) Increased plasma endothelin 1 in acute ischemic stroke. Stroke 23:1014-1016