Hypersusceptibility to DMCM-induced seizures during diazepam withdrawal in mice: Evidence for upregulation of NMDA receptors

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 357, Issue 3, 1998, Pages 309-315

  Tsuda, Makoto ^a   Shimizu, Norifumi ^a   Yajima, Yoshinori ^a   Suzuki, Tsutomu ^a   Misawa, Miwa ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

7 Chlorokynurenic acid; 3H MK 801 binding; Cerebral cortex; Diazepam withdrawal; Ifenprodil; MK 801; NMDA receptor

Indexed keywords

4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; BENZODIAZEPINE RECEPTOR INVERSE STIMULATING AGENT; DIAZEPAM; DIZOCILPINE; IFENPRODIL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DEPENDENCE; DRUG EFFECT; DRUG WITHDRAWAL; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MOUSE; NONHUMAN; SEIZURE; SEIZURE THRESHOLD;

ANIMALS; ANTICONVULSANTS; CARBOLINES; CEREBRAL CORTEX; CONVULSANTS; DIAZEPAM; DIZOCILPINE MALEATE; MALE; MEMBRANES; MICE; NEUROPROTECTIVE AGENTS; RECEPTORS, N-METHYL-D-ASPARTATE; SEIZURES; SPERMIDINE; SUBSTANCE WITHDRAWAL SYNDROME; UP-REGULATION;

EID: 0031938953     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005172     Document Type: Article

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