Downregulation of 5′-nucleotidase in rabbit heart during coronary underperfusion

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 274, Issue 2 43-2, 1998, Pages

  Gustafson, Lori A ^a,b   Kroll, Keith ^a  

^a University of Washington   (United States)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Adenosine; Ischemia; Nuclear magnetic resonance; Nucleotides; Phosphoenergetics

Indexed keywords

5' NUCLEOTIDASE; ADENOSINE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; INOSINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOWN REGULATION; ENERGY METABOLISM; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; INDICATOR DILUTION CURVE; KINETICS; MATHEMATICAL MODEL; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RABBIT;

5'-NUCLEOTIDASE; ADENOSINE KINASE; ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; CORONARY CIRCULATION; CORONARY VESSELS; CYTOSOL; DOWN-REGULATION; ENERGY METABOLISM; HYDROLYSIS; KINETICS; LACTIC ACID; MAGNETIC RESONANCE SPECTROSCOPY; MATHEMATICS; MODELS, BIOLOGICAL; MYOCARDIUM; PHOSPHOCREATINE; PURINES; RABBITS;

EID: 0031938685     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.274.2.h529     Document Type: Article

References (33)

1. Arch, J. R. S., and E. A. Newsholme. The control of the metabolism and the hormonal role of adenosine. Essays Biochem. 14: 82-123, 1978.
2. Bak, M. I., and J. S. Ingwall. Acidosis during ischemia promotes adenosine triphosphate resynthesis in postischemic rat heart. In vivo regulation of 5′-nucleotidase. J. Clin. Invest. 93: 40-49, 1994.
3. Bradamante, S., F. Piccinini, C. Delu, M. Janssen, and J. W. de Jong. NMR evaluation of changes in myocardial high energy metabolism produced by repeated short periods of ischemia. Biochim. Biophys. Acta 1243: 1-8, 1995.
4. Darvish, A., R. W. Pomerantz, P. G. Zografides, and P. J. Metting. Contribution of cytosolic and membrane-bound 5′-nucleotidase to cardiac adenosine production. Am. J. Physiol. 271 (Heart Circ. Physiol. 40): H2162-H2167, 1996.
5. Decking, U. K., G. Schlieper, K. Kroll, and J. Schrader. Hypoxia-induced inhibition of adenosine kinase potentiates adenosine release. Circ. Res. 81: 154-164, 1997.
6. 15O]oxygen tracer data for estimating oxygen consumption. Am. J. Physiol. 270 (Heart Circ. Physiol. 39): H1115-H1130, 1996.
7. Downey, J. M., G. S. Liu, and J. D. Thorton. Adenosine and the anti-infarct effects of preconditioning. Cardiovasc. Res. 27: 3-8, 1993.
8. Forman, M. B., C. E. Velasco, and E. K. Jackson. Adenosine attenuates reperfusion injury following regional myocardial ischemia. Cardiovasc. Res. 27: 9-17, 1993.
9. Gorman, M. W., M. X. He, C. S. Hall, and H. V. Sparks. Inorganic phosphate as a regulator of adenosine formation in the isolated guinea pig heart. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H913-H920, 1997.
10. Goto, M., M. V. Cohen, D. G. L. van Wylen, and J. M. Downey. Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection. J. Mol. Cell Cardiol. 28: 447-454, 1996.
11. He, M. X., M. W. Gorman, G. D. Romig, R. A. Meyer, and H. V. Sparks. Adenosine formation and energy status during hypoperfusion and 2-deoxyglucose infusion. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H917-H926, 1991.
12. Heineman, F. W., J. Eng, B. A. Berkowitz, and R. S. Balaban. NMR spectral analysis of kinetic data using natural lineshapes. Magn. Reson. Med. 13: 490-497, 1990.
13. Henrichs, K. J., H. Matsuoka, and J. Schaper. Influence of repetitive coronary occlusions on myocardial adenine nucleosides, high energy phosphates and ultrastructure. Basic Res. Cardiol. 82: 557-565, 1987.
14. Itoh, R., J. Oka, and H. Ozasa. Regulation of rat heart cytosol 5′-nucleotidase by adenylate energy charge. Biochem. J. 235: 847-851, 1986.
15. Jennings, R. B., H. K. Hawkins, J. E. Lowe, M. L. Hill, S. Klotman, and K. A. Reimer. Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog. Am. J. Pathol. 92: 203-216, 1978.
16. King, R. B., A. Deussen, G. R. Raymond, and J. B. Bassingthwaighte. A vascular transport operator. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H2196-H2208, 1993.
17. Kitakaze, M., M. Hori, and T. Kamada. Role of adenosine and its interaction with α-adrenoceptor activity in ischaemic and reperfusion injury of the myocardium. Cardiovasc. Res. 27: 18-27, 1993.
18. 1-Adrenoceptor activation mediates the infarct size-limiting effect of ischemic preconditioning through augmentation of 5′-nucleotidase activity. J. Clin. Invest. 93: 2197-2205, 1994.
19. Kitakaze, M., M. Hori, S. Takashima, H. Sato, M. Inoue, and T. Kamada. Ischemic preconditioning increases adenosine release and 5′-nucleotidase activity during myocardial ischemia and reperfusion in dogs. Implications for myocardial salvage. Circulation 87: 208-215, 1993.
20. Kitakaze, M., T. Minamino, K. Node, K. Komamura, and M. Hori. Activation of ecto-5′-nucleotidase and cardioprotection by ischemic preconditioning. Basic Res. Cardiol. 91: 23-26, 1996.
21. Kroll, K., U. K. M. Decking, K. Dreikorn, and J. Schrader. Rapid turnover of the AMP-adenosine metabolic cycle in the guinea pig heart. Circ. Res. 73: 846-856, 1993.
22. Kroll, K., D. J. Kinzie, and L. A. Gustafson. Open system kinetics of myocardial phosphoenergetics during coronary underperfusion. Am. J. Physiol. 272 (Heart Circ. Physiol. 41): H2563-H2576, 1997.
23. Mallet, R. T., Y. H. Kang, N. Mukohara, and R. Bunger. Use of cytosolic metabolite patterns to estimate free magnesium in normoxic myocardium. Biochim. Biophys. Acta 1139: 239-247, 1992.
24. Matherne, G. P., J. P. Headrick, S. Berr, and R. M. Berne. Metabolic and functional responses of immature and mature rabbit hearts to hypoperfusion, ischemia, and reperfusion. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H2141-H2153, 1993.
25. Murry, C. E., V. J. Richard, K. A. Reimer, and R. B. Jennings. Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode. Circ. Res. 66: 913-931, 1990.
26. Newby, A. C. The interaction of inhibitors with adenosine metabolizing enzymes in intact isolated cells. Biochem. Pharmacol. 30: 2611-2615, 1981.
27. Newby, A. C. The pigeon heart 5′-nucleotidase responsible for ischaemia-induced adenosine formation. Biochem. J. 253: 123-130, 1988.
28. Reimer, K. A., C. E. Murry, I. Yamasawa, M. L. Hill, and R. B. Jennings. Four brief periods of myocardial ischemia cause no cumulative ATP loss or necrosis. Am. J. Physiol. 251 (Heart Circ. Physiol. 20): H1306-H1315, 1986.
29. Swain, J. L., R. L. Sabina, J. J. Hines, J. C. Greenfield, Jr., and E. W. Holmes. Repetitive episodes of brief ischaemia (12 min) do not produce a cumulative depletion of high energy phosphate compounds. Cardiovasc. Res. 18: 264-269, 1984.
30. Vary, T. C., E. T. Angelakos, and S. W. Schaffer. Relationship between adenine nucleotide metabolism and irreversible ischemic tissue damage in isolated perfused rat heart. Circ. Res. 45: 218-225, 1979.
31. 0-ATPase. Circulation 91: 2810-2818, 1995.
32. Wagner, D. R., F. Bontemps, and G. van den Berghe. The AMP-adenosine cycle is active during normoxia and impaired in ATP depletion in isolated rabbit cardiomyocytes. Adv. Exp. Med. Biol. 370: 323-326, 1994.
33. Yamazaki, Y., V. L. Truong, and J. M. Lowenstein. 5′-Nucleotidase I from rabbit heart. Biochemistry 30: 1503-1509, 1991.