Activation of ecto-5′-nucleotidase and cardioprotection by ischemic preconditioning

Basic Research in Cardiology

Volumn 91, Issue 1, 1996, Pages 23-26

  Kitakaze, M ^a   Minamino, T ^a   Node, K ^a   Komamura, K ^a   Hori, M ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

1 adrenoceptor; Adenosine; Ischemia; Myocardial infarction; Protein kinase C

Indexed keywords

ADENOSINE; ECTO 5' NUCLEOTIDASE; PROTEIN KINASE C;

CONDITIONING; ENZYME ACTIVATION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; NONHUMAN; SHORT SURVEY;

5'-NUCLEOTIDASE; ADENOSINE; ANIMALS; ENZYME ACTIVATION; HUMANS; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION;

EID: 0030031450     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Hori M. Kitakaze M (1991) Adenosine. the heart and coronary circulation (Brief Review). Hypertension 18: 565-574
2. 1-Adrenoceptor activity regulates release of adenosine from the ischemic myocardium in dogs. Circ Res 60: 631-639
3. Kitakaze M, Hori M, Kamada T (1993) The role of adenosine and its interaction with alpha-adrenoceptor activity in myocardial ischemic and repefusion injury (Brief Review). Cardiovasc Res 27: 18-27
4. Kitakaze M, Hori M, Takashima S, Sato H. Inoue M, Kamada T (1993) Ischemic preconditioning increases adenosine release and 5′-nucleotidase activity during myocardial ischemia and reperfusion in dogs: Implication for myocardial salvage. Circulation 87: 208-215
5. Kitakaze M, Hori M, Morioka T, Minamino T, Takashima S, Sato H, Shinozaki Y, Chujo M, Mori H, Inoue M, Kamada T (1994) The infarct size-limiting effect of ischemic preconditioning is blunted by inhibition of 5′-nucleotidase activity and attenuation of adenosine release. Circulation 89: 1237-1246
6. 1-adrenoceptor activation mediates the infarct size limiting effect of ischemic preconditioning through augmentation of 5′-nucleotidase activity. J Clin Invest 93: 2197-2207
7. 1-adrenoceptor activation increases ectosolic 5′-nucleotidase activity and adenosine release in rat cardiomyocytes by activing protein kinase C. Circulation 91: 2226-2234
8. Kitakaze M, Node K, Minamino T, Komamura K, Funaya H, Shinozaki Y, Chujo M, Mori H, Inoue M, Hori M, Kamada T. The role of activation of protein kinase C in the infarct size-limiting effect of ischemic preconditioning through activation of ecto-5′-nucleotidase. Circulation (in press)
9. Komamura K, Kitakaze M, Nishida M, Naka K, Tamai J, Uematsu M, Koretsune Y, Nanto S, Hori M, Inoue M, Kamada T, Kodama K (1994) Progressive decreases in coronary vein flow during reperfusion in acute myocardial infarction: A clinical documentation of no-reflow phenomenon following successful thrombolysis. J Am Coll Cardiol 24: 370-377
10. 1 adenosine receptors in rabbit heart. Circulation 84: 350-356
11. Murry CE, Jennings RB. Reimer KA (1986) Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136
12. Nakagawa Y. Ito H, Kitakaze M, Kusuoka H, Hon M, Kuzuya T, Higashino Y, Fujii K, Minamino T (1995) Effect of angina pectoris on myocardial protection in patients with reperfused anterior wall myocardial infarction: Retrospective evidence of "preconditioning". J Am Coll Cardiol 25: 1076-1083