The effects of nitric oxide and peroxynitrite on interleukin-8 and elastase from lipopolysaccharide-stimulated whole blood

Anesthesia and Analgesia

Volumn 86, Issue 2, 1998, Pages 427-431

  Cuthbertson, Brian H ^a   Galley, Helen F ^a   Webster, Nigel R ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE; INTERLEUKIN 8; NITRIC OXIDE; PEROXYNITRITE;

ARTICLE; DRUG EFFECT; ENZYME RELEASE; HUMAN; HUMAN EXPERIMENT; HYPOXEMIA; INFLAMMATION; LUNG INJURY; MALE; NORMAL HUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PULMONARY HYPERTENSION;

FREE RADICAL SCAVENGERS; HUMANS; INTERLEUKIN-8; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDES; MALE; MOLSIDOMINE; NITRATES; NITRIC OXIDE; TRIAZOLES;

EID: 0031938482     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199802000-00039     Document Type: Article

References (26)

1. Rossaint R, Falke KJ, Lopez F, et al. Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 1993;328: 399-405.
2. Cuthbertson BH, Stott S, Webster NR. Use of inhaled nitric oxide in British ICU. Br J Anaesth 1997;78:696-700.
3. Donnelly SC, Strieter RM, Kunkel SL, et al. Chemotactic cytokines in the established adult respiratory distress syndrome and at-risk patients. Chest 1994;105:98S-9S.
4. Miller EJ, Cohen AB, Nagao S, et al. Elevated levels of NAP-1/ interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. Am Rev Respir Dis 1992;146:427-32.
5. Chollet-Martin S, Gatecel C, Kermarrec N, et al. Alveolar neutrophil functions and cytokine levels in patients with the adult respiratory distress syndrome during nitric oxide inhalation. Am J Respir Crit Care Med 1996;153:985-90.
6. Lengas A, Poletti V, Pacifico L, et al. Acute lung inflammation: neutrophil elastase versus neutrophils in the bronchoalveolar lavage-neutrophil elastase reflects better inflammatory intensity. Intensive Care Med 1994;20:354-59.
7. Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996; 271:C1424-37.
8. Kooy NW, Royal JA, Ye YZ, et al. Evidence for in vivo peroxynitrite in human acute lung injury. Am J Respir Crit Care Med 1995;151:1250-4.
9. Cuthbertson BH, Galley HF, Webster NR. Effect of exogenous nitric oxide and superoxide on interleukin-8 from human polymorphonuclear leucocytes. Br J Anaesth 1997;78:714-7.
10. Moilanen E, Vuorinen P, Kankaanranta H, et al. Inhibition by nitric oxide-donors of human polymorphonuclear leucocyte functions. Br J Pharmacol 1993;109:852-8.
11. Cassatella MA, Bazzoni F, Ceska M, et al. IL-8 production by human polymorphonuclear leukocytes. J Immunol 1992;148: 3216-20.
12. Darius H, Grodzinska L, Meyer J. The effects of the nitric oxide donors molsidomine and SIN-I on human polymorphonuclear leucocyte function in vitro and ex vivo. Eur J Clin Pharmacol 1992;43:629-33.
13. Petersen F, Van Damme J, Flad HD, Brandt E. Neutrophil-activating polypeptides IL-8 and NAP-2 induce identical signal transduction pathways in the regulation of lysosomal enzyme release. Lymph Cytokine Res 1991;10:35-41.
14. Nogare AR, Yarbrough WC Jr. A comparison of the effects of intact and deacylated lipopolysaccharide on human polymorphonuclear leukocytes. J Immunol 1990;144:1404-10.
15. Gow AJ, Eu JP, McMahon TJ, et al. Nitric oxide in the respiratory cycle [abstract]. Jpn J Pharmacol 1997;75(Suppl 1):18P.
16. Andrew PJ, Harant H, Lindley IJ. Nitric oxide regulates IL-8 expression in melanoma cells at the transcriptional level. Biochem Biophys Res Commun 1995;214:949-56.
17. Villarete LH, Remick DG. Nitric oxide regulation of IL-8 expression in human endothelial cells. Biochem Biophys Res Commun 1995;211:671-6.
18. Peng HB, Libby P, Liao JK. Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NF-kappa B. J Biol Chem 1995;270:14214-9.
19. Pieper GM, Clarke GA, Gross GJ. Stimulatory and inhibitory action of nitric oxide donor agents versus nitrovasodilators on reactive oxygen production by isolated polymorphonuclear leukocytes. J Pharmacol Exp Ther 1994;269:451-6.
20. Forslund T, Sundqvist T. Nitric oxide reduces hydrogen peroxide production from human polymorphonuclear neutrophils. Eur J Clin Invest 1995;25:9-14.
21. Murad F. Signal transduction using nitric oxide and cyclic guanosine monophosphate. JAMA 1996;276:1189-92.
22. Eckle I, Kolb G, Havemann K. Regulation of neutrophil functions by elastase-generated IgG fragments. Arch Immunol Ther Exp 1992;40:43-7.
23. Groeneveld AB, Raijmakers PG, Hack CE, Thijs LG. Interleukin 8-related neutrophil elastase and the severity of the adult respiratory distress syndrome. Cytokine 1995;7:46-52.
24. Jorens PG, Richman-Eisenstat JB, Housset BP, et al. Interleukin-8 induces neutrophil accumulation but not protease secretion in the canine trachea. Am J Physiol 1992;263:L708-13.
25. Endo S, Inada K, Yamashita H, et al. The inhibitory actions of protease inhibitors on the production of polymorphonuclear leukocyte elastase and interleukin 8. Res Commun Chem Pathol Pharmacol 1993;82:27-33.
26. Padrines M, Wolf M, Walz A, Baggiolini M. Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3. FEBS Letts 1994;352:231-35.