메뉴 건너뛰기




Volumn 26, Issue 1, 1998, Pages 1-12

Steroid formation in osteoblast-like cells

Author keywords

Enzyme activity; Osteoblast like cells; Osteoporosis; Reverse transcription polymerase reaction; Steroid formation

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANDROGEN RECEPTOR; AROMATASE; ESTROGEN RECEPTOR; MESSENGER RNA; PROGESTERONE RECEPTOR; STEROID 5ALPHA REDUCTASE; STERYL SULFATASE; TESTOSTERONE 17BETA DEHYDROGENASE;

EID: 0031936448     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/030006059802600101     Document Type: Article
Times cited : (51)

References (30)
  • 1
    • 0018263644 scopus 로고
    • Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal male
    • Baran DT, Bergfeld MA, Teitelbaum SL, et al: Effect of testosterone therapy on bone formation in an osteoporotic hypogonadal male. Calcif Tissue Res 1978; 26: 103-106.
    • (1978) Calcif Tissue Res , vol.26 , pp. 103-106
    • Baran, D.T.1    Bergfeld, M.A.2    Teitelbaum, S.L.3
  • 2
    • 0023148432 scopus 로고
    • Osteoporosis in men with idiopathic hypogonadotropic hypogonadism
    • Finkelstein JS, Klibanski A, Neer RM, et al: Osteoporosis in men with idiopathic hypogonadotropic hypogonadism. Ann Intern Med 1987; 106: 354-361.
    • (1987) Ann Intern Med , vol.106 , pp. 354-361
    • Finkelstein, J.S.1    Klibanski, A.2    Neer, R.M.3
  • 3
    • 0024461620 scopus 로고
    • Increases in bone density during treatment of men with idiopathic hypogonadotropic hypogonadism
    • Finkelstein JS, Klibanski A, Neer RM, et al: Increases in bone density during treatment of men with idiopathic hypogonadotropic hypogonadism. J - Clin Endocrinol Metab 1989; 69: 776-783.
    • (1989) J - Clin Endocrinol Metab , vol.69 , pp. 776-783
    • Finkelstein, J.S.1    Klibanski, A.2    Neer, R.M.3
  • 4
    • 0025185656 scopus 로고
    • Steroid receptors in human osteoblast-like cells
    • Etienne MC, Fishel JL, Milano G, et al: Steroid receptors in human osteoblast-like cells. Eur J Cancer 1990; 26: 807-810.
    • (1990) Eur J Cancer , vol.26 , pp. 807-810
    • Etienne, M.C.1    Fishel, J.L.2    Milano, G.3
  • 5
    • 0023909432 scopus 로고
    • Evidence of estrogen receptors in normal osteoblast-like cells
    • Eriksen EF, Colvard DS, Berg NJ, et al: Evidence of estrogen receptors in normal osteoblast-like cells. Science 1988; 241: 84-86.
    • (1988) Science , vol.241 , pp. 84-86
    • Eriksen, E.F.1    Colvard, D.S.2    Berg, N.J.3
  • 6
    • 0025954856 scopus 로고
    • Androgen receptors in osteoblast-like cell lines
    • Orwoll ES, Stribrska L, Ramsey EF, et al: Androgen receptors in osteoblast-like cell lines. Calcif Tissue Int 1991; 49: 183-187.
    • (1991) Calcif Tissue Int , vol.49 , pp. 183-187
    • Orwoll, E.S.1    Stribrska, L.2    Ramsey, E.F.3
  • 7
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man
    • Smith EP, Boyd J, Frank GR, et al: Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man. N Engl J Med 1994; 331: 1056-1061.
    • (1994) N Engl J Med , vol.331 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank, G.R.3
  • 8
    • 0028792229 scopus 로고
    • Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens
    • Morishima A, Grumbach MM, Simpson ER, et al: Aromatase deficiency in male and female siblings caused by a novel mutation and the physiological role of estrogens. J Clin Endocrinol Metab 1995; 80: 3689-3698.
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3689-3698
    • Morishima, A.1    Grumbach, M.M.2    Simpson, E.R.3
  • 9
    • 0029133122 scopus 로고
    • Aromatase in hone cell: Association with osteoporosis in postmenopausal women
    • Nawata H, Tanaka S, Tanaka S, et al: Aromatase in hone cell: association with osteoporosis in postmenopausal women. J Steroid Biochem Mol Biol 1995; 53: 165-174.
    • (1995) J Steroid Biochem Mol Biol , vol.53 , pp. 165-174
    • Nawata, H.1    Tanaka, S.2    Tanaka, S.3
  • 10
    • 0026666656 scopus 로고
    • Estrogen synthesis by osteoblast cell lines
    • Purohit A, Flanagan AM, Reed MJ: Estrogen synthesis by osteoblast cell lines. Endocrinology 1992; 131: 2027-2029.
    • (1992) Endocrinology , vol.131 , pp. 2027-2029
    • Purohit, A.1    Flanagan, A.M.2    Reed, M.J.3
  • 11
    • 0029930671 scopus 로고    scopus 로고
    • Osteoblast cells (MG 63 and HOS) have aromatase and 5α-reductase activities
    • Shimodaira K, Fujikawa H, Okura F, et al: Osteoblast cells (MG 63 and HOS) have aromatase and 5α-reductase activities. Biochem Mol Biol Int 1996; 39: 109-116.
    • (1996) Biochem Mol Biol Int , vol.39 , pp. 109-116
    • Shimodaira, K.1    Fujikawa, H.2    Okura, F.3
  • 13
    • 0026772423 scopus 로고
    • Androstenedione metabolism in cultured human osteoblast-like cells
    • Bruch HR, Wolf L, Budde R, et al: Androstenedione metabolism in cultured human osteoblast-like cells. J Endocrinol Metab 1992; 75: 101-105.
    • (1992) J Endocrinol Metab , vol.75 , pp. 101-105
    • Bruch, H.R.1    Wolf, L.2    Budde, R.3
  • 14
    • 0029648983 scopus 로고
    • Effect of estradiol on 5α-reductase activity in osteoblast-like cell (UMR 106-01)
    • Suwa H, Fujikawa H, Shimodaira K, et al: Effect of estradiol on 5α-reductase activity in osteoblast-like cell (UMR 106-01) [In Japanese] Nippon Naibunpi Gakkai Zasshi; 1995; 71: 651-658.
    • (1995) Nippon Naibunpi Gakkai Zasshi , vol.71 , pp. 651-658
    • Suwa, H.1    Fujikawa, H.2    Shimodaira, K.3
  • 15
    • 0031283502 scopus 로고    scopus 로고
    • 3β-hydroxysteroid dehydrogenase activity in human osteoblast-like cells
    • in press
    • Kuwano Y, Fujikawa H, Watanabe A, et al: 3β-hydroxysteroid dehydrogenase activity in human osteoblast-like cells. Endocr J 1997; (in press).
    • (1997) Endocr J
    • Kuwano, Y.1    Fujikawa, H.2    Watanabe, A.3
  • 16
    • 0023277545 scopus 로고
    • Single-step of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N: Single-step of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 17
    • 0024513718 scopus 로고
    • Androgens directly stimulate proliferation of bone cells in vitro
    • Kasperk CH, Wergedal JE, Farley JR et al: Androgens directly stimulate proliferation of bone cells in vitro. Endocrinology 1989; 124: 1576-1578.
    • (1989) Endocrinology , vol.124 , pp. 1576-1578
    • Kasperk, C.H.1    Wergedal, J.E.2    Farley, J.R.3
  • 18
    • 0025881025 scopus 로고
    • High-affinity androgen and androgenic regulation of steady state messenger ribonucleic acid levels of α1(I)-procollagen and transforming factor β in human osteoblast-like osteosarcomaz cells
    • Benz DJ, Haussler MR, Thomas MA, et al: High-affinity androgen and androgenic regulation of steady state messenger ribonucleic acid levels of α1(I)-procollagen and transforming factor β in human osteoblast-like osteosarcomaz cells. Endocrinology 1991; 128: 2723-2730.
    • (1991) Endocrinology , vol.128 , pp. 2723-2730
    • Benz, D.J.1    Haussler, M.R.2    Thomas, M.A.3
  • 19
    • 0025303307 scopus 로고
    • Structural and biochemical properties of cloned and expressed human and rat steroid 5α-reductases
    • Andersson S, Russell DW: Structural and biochemical properties of cloned and expressed human and rat steroid 5α-reductases. Proc Natl Acad Sci USA 1990; 87: 3640-3644.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3640-3644
    • Andersson, S.1    Russell, D.W.2
  • 20
    • 0029096372 scopus 로고
    • The molecular biology of androgenic 17β-hydroxysteroid dehydrogenases
    • Andersson S, Geissler WM, Patel S, et al: The molecular biology of androgenic 17β-hydroxysteroid dehydrogenases. J Steroid Biochem Mol Biol 1995; 53: 37-39.
    • (1995) J Steroid Biochem Mol Biol , vol.53 , pp. 37-39
    • Andersson, S.1    Geissler, W.M.2    Patel, S.3
  • 21
    • 0028173037 scopus 로고
    • 17β-hydroxysteroid dehydrogenase type 2: Chromosomal assignment and progestin regulation of gene expression in human endometrium
    • Casey ML, MacDonald PC, Andersson S: 17β-hydroxysteroid dehydrogenase type 2: chromosomal assignment and progestin regulation of gene expression in human endometrium. J Clin Invent 1994; 94: 2135-2141.
    • (1994) J Clin Invent , vol.94 , pp. 2135-2141
    • Casey, M.L.1    MacDonald, P.C.2    Andersson, S.3
  • 22
    • 0027225486 scopus 로고
    • Expression cloning and characterization of human 17β-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteroid dehydrogenase activity
    • Wu L, Einstein M, Geissler WM, et al: Expression cloning and characterization of human 17β-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20α-hydroxysteroid dehydrogenase activity. J Biol Chem 1993; 268: 12964-12969.
    • (1993) J Biol Chem , vol.268 , pp. 12964-12969
    • Wu, L.1    Einstein, M.2    Geissler, W.M.3
  • 23
    • 0027930787 scopus 로고
    • Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3
    • Geissler WM, Davis DL, Wu L, et al: Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3. Nature Genetics 1994; 7: 34-39.
    • (1994) Nature Genetics , vol.7 , pp. 34-39
    • Geissler, W.M.1    Davis, D.L.2    Wu, L.3
  • 24
    • 0028847134 scopus 로고
    • Molecular cloning of a novel widely expressed human 80 KDa 17β-hydroxysteroid dehydrogenase
    • Adamski J, Normand T, Leenders F, et al: Molecular cloning of a novel widely expressed human 80 KDa 17β-hydroxysteroid dehydrogenase. Biochem J 1995; 311: 437-443.
    • (1995) Biochem J , vol.311 , pp. 437-443
    • Adamski, J.1    Normand, T.2    Leenders, F.3
  • 25
    • 0028905564 scopus 로고
    • Functional estrogen receptors in a human preosteoclastic cell line
    • Fiorelli G, Goli F, Petilli M, et al: Functional estrogen receptors in a human preosteoclastic cell line. Proc Natl Acad Sci USA 1995; 92: 2672-2676.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2672-2676
    • Fiorelli, G.1    Goli, F.2    Petilli, M.3
  • 26
    • 0026777433 scopus 로고
    • Increased osteoclast development after estrogen loss: Mediation by interleukin-6
    • Jilka RL, Hangoc G, Girasole G, et al: Increased osteoclast development after estrogen loss: mediation by interleukin-6. Science 1992; 257: 88-91.
    • (1992) Science , vol.257 , pp. 88-91
    • Jilka, R.L.1    Hangoc, G.2    Girasole, G.3
  • 27
    • 0028245512 scopus 로고
    • Analysis of gene expression in human bone biopsies by polymerase chain reaction: Evidence for enhanced cytokine expression in postmenopausal osteoporosis
    • Ralston SH: Analysis of gene expression in human bone biopsies by polymerase chain reaction: evidence for enhanced cytokine expression in postmenopausal osteoporosis. J Bone Miner Res 1994; 9: 883-890.
    • (1994) J Bone Miner Res , vol.9 , pp. 883-890
    • Ralston, S.H.1
  • 28
    • 0026516415 scopus 로고
    • 17β-Estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoclasts in vitro: A potential mechanism for the antiosteoporotic effect of estrogens
    • Girasole G, Jilka RL, Passeri G, et al: 17β-Estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoclasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens. J Clin Invest 1992; 89: 883-891.
    • (1992) J Clin Invest , vol.89 , pp. 883-891
    • Girasole, G.1    Jilka, R.L.2    Passeri, G.3
  • 29
    • 0029023837 scopus 로고
    • The role of cytokines and sulfatase inhibitors in regulating estrogen synthesis in breast tumors
    • Reed MJ, Purohit A, Duncan LJ, et al: The role of cytokines and sulfatase inhibitors in regulating estrogen synthesis in breast tumors. J Steroid Biochem Mol Biol 1995; 53: 413-420.
    • (1995) J Steroid Biochem Mol Biol , vol.53 , pp. 413-420
    • Reed, M.J.1    Purohit, A.2    Duncan, L.J.3
  • 30
    • 0028322040 scopus 로고
    • The interaction of cytokines in regulating oestradiol 17 beta-hydroxysteroid dehydrogenase activity in MCF-7
    • Duncan LJ, Coldham NG, Reed MJ: The interaction of cytokines in regulating oestradiol 17 beta-hydroxysteroid dehydrogenase activity in MCF-7. J Steroid Biochem Mol Biol 1994; 49: 63-68.
    • (1994) J Steroid Biochem Mol Biol , vol.49 , pp. 63-68
    • Duncan, L.J.1    Coldham, N.G.2    Reed, M.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.