Monitoring adenoviral p53 transduction efficiency by yeast functional assay

Gene Therapy

Volumn 5, Issue 3, 1998, Pages 339-344

  Tada, M ^a   Sakuma, S ^a   Iggo, R D ^b   Saya, H ^c   Sawamura, Y ^a   Fujiwara, T ^d   Roth, J A ^e  

^a HOKKAIDO UNIVERSITY   (Japan)

^b SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

^c KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^d OKAYAMA UNIVERSITY   (Japan)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Adenovirus; p53; Transcripts; Transduction efficiency; Yeast p53 functional assay

Indexed keywords

MESSENGER RNA; PROTEIN P21; PROTEIN P53; VIRUS VECTOR;

ADENOVIRUS; ARTICLE; CONTROLLED STUDY; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; GLIOBLASTOMA; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; YEAST;

ADENOVIRIDAE; DNA VIRUSES;

EID: 0031933020     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300605     Document Type: Article

References (14)

1. Liu T-J et al. Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus Cancer Res 1994; 54: 3662-3667.
2. Gannon JV, Greaves R, Iggo R, Lane DP. Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J 1990, 9: 15951602.
3. Sakuma S et al. Receptor protein tyrosine kinase DDR is upregulated by p53 protein. FEBS Lett 1996; 398: 165-169.
4. Macleod KF et al. p53-Dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 1995; 9: 935-944.
5. Canman CE, Gilmer TM, Courts SB, Kastan MB. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev 1995; 9: 600-611
6. Wu X, Bayle JH, Olson D, Levine AJ. The p53-mdm-2 autoregulatory feedback loop. Genes Dev 1993; 7: 1126-1132.
7. Flaman J-M et al. A simple p53 functional assay for screening cell lines, blood, and tumors. Proc Natl Acad Sci USA 1995; 92: 3963-3967.
8. el-Deiry WS et al WAF 1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817-825
9. Tada M et al. Clonality and stability of the p53 gene in human astrocytic tumor cells - quantitative analysis of p53 gene mutations by yeast functional assay. Int J Cancer 1996; 67: 447-450.
10. Fujiwara T et al. Induction of chemosensitivity in human lung cancer cells in vivo by adenovirus-mediated transfer of the wildtype p53 gene. Cancer Res 1994; 54: 2287-2291.
11. Liebermann DA, Hoffman B, Steinman RA. Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways Oncogene 1995; 11: 199-210.
12. Waridel F et al. Field cancerisation and polyclonal p53 mutation in the upper aerodigestive tract. Oncogene 1997; 14: 163-169.
13. Bodell WJ, Aida T, Berger MS, Rosenblum ML. Increased repair of O6-aIkylguanine DNA adducts in glioma-derived human cells resistant to the cytotoxic and cytogenetic effects of l,3-bis(2chloroethyl)-l-nitrosourea. Carcinogenesis 1986; 7: 879-883.
14. Osborn M et al. Expression of glial and vimentin type intermediate filaments in cultures derived from human glial material. Differentiation 1981; 19: 161-167