Preemptive intrathecal ketamine delays mechanical hyperalgesia in the neuropathic rat

Anesthesia and Analgesia

Volumn 86, Issue 3, 1998, Pages 557-560

  Hartrick, Craig T ^a   Wise, Jeffrey J ^a   Patterson, Jon S ^b  

^a WILLIAM BEAUMONT HOSPITAL   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KETAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; HYPERALGESIA; INTRATHECAL DRUG ADMINISTRATION; NONHUMAN; PAIN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SCIATIC NERVE;

ANESTHETICS, DISSOCIATIVE; ANIMALS; FEMALE; HYPERALGESIA; INJECTIONS, SPINAL; KETAMINE; NERVE COMPRESSION SYNDROMES; PAIN; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; STRESS, MECHANICAL;

EID: 0031932846     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199803000-00022     Document Type: Article

References (25)

1. Roberts WJ. A hypothesis on the physiological basis for causalgia and related pains. Pain 1986;24:297-311.
2. Seltzer Z, Cohn S, Ginzgurg R, Berlin B. Modulation of neuropathic pain behavior in rats by spinal disinhibition and NMDA receptor blockade of injury discharge. Pain 1991;45:69-75.
3. Woolf CJ, Thompson SWN. The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation: implications for treatment of post-injury pain hypersensitivity states. Pain 1991;44:293-9.
4. Mao J, Price DD, Mayer DJ, Hayes RL. Intrathecal MK-801 and local nerve anesthesia synergistically reduce nociceptive behaviors in rats with experimental peripheral mononeuropathy. Brain Res 1992;576:254-62.
5. Mao J, Price DD, Hayes RL, et al. Intrathecal treatment with dextrophan or ketamine potently reduces pain-related behaviors in a rat model of peripheral mononeuropathy. Brain Res 1993;605:164-8.
6. Smith GD, Wiseman J, Harrison SM, et al. Pretreatment with MK-801, a non-competitive NMDA antagonist, prevents development of mechanical hyperalgesia in a rat model of chronic neuropathy, but not in a model of chronic inflammation. Neurosci Lett 1993;165:79-83.
7. Munglani R, Bond A, Smith GD, et al. Changes in neuronal markers in a mononeuropathic rat model: relationship between neuropeptide Y, pre-emptive drug treatment and long-term mechanical hyperalgesia. Pain 1995;63:21-31.
8. Smith GD, Harrison SM, Birch PJ. Peri-administration of clonidine or MK801 delays but does not prevent the development of mechanical hyperalgesia in a model of mononeuropathy in the rat. Neurosci Lett 1995;192:33-6.
9. Bennett GJ, Xie YK. A peripheral mononeuropathy in rats that produces disorders of pain sensation like those seen in man. Pain 1988;33:87-107.
10. Elliot KJ, Brodsky M, Hynansky AD, et al. Dextromethorphan suppresses both formalin-induced nociceptive behavior and formalin-induced increase in spinal cord c-fos mRNA. Pain 1995;61:401-9.
11. Rice AS, McMahon SB. Pre-emptive intrathecal administration of an NMDA receptor antagonist (AP-5) prevents hyper-reflexia in a model of persistent visceral pain. Pain 1994;57:335-40.
12. Davar G. MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathy. Brain Res 1991;553:327-30.
13. Qian J, Brown SD, Carlton SM. Systemic ketamine attenuates nociceptive behaviors in a rat model of peripheral neuropathy. Brain Res 1996;715:51-62.
14. Brockmeyer DM, Kendig JJ. Selective effects of ketamine on aminoacid-mediated pathways in neonatal rat spinal cord. Br J Anaesth 1995;74:79-84.
15. Ren K, Williams GM, Hylden JL, et al. The intrathecal administration of excitatory aminoacid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats. Eur J Pharmacol 1992;219:235-43.
16. Yamakura T, Mori H, Masaki H, et al. Different sensitivities of NMDA receptor channel subtypes to non-competitive antagonists. Neuroreport 1993;4:687-90.
17. Orser BA, Pennefather PS, MacDonald JF. Multiple mechanisms of ketamine blockade of N-methyl-D-aspartate receptors. Anesthesiology 1997;86:903-17.
18. Tao R, Auerbach SB. Anesthetics block morphine-induced increases in serotonin release in rat CNS. Synapse 1994;18:307-14.
19. Frenkel C, Urban BW. Molecular actions of racemic ketamine on human CNS sodium channels. Br J Anaesth 1992;69:292-7.
20. Coyle DE, Sehlhorst CS, Mascari C. Female rats are more susceptible to the development of neuropathic pain using the partial sciatic nerve ligation (PSNL) model. Neurosci Lett 1995;186: 135-8.
21. Dickenson AH, Sullivan AF. Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurones. Neurosci Lett 1987;83:207-11.
22. Dickenson AH, Sullivan AF. Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurons in the rat. Brain Res 1990;506:31-9.
23. Rockermann MG, Seeling W, Bischof C, et al. Prophylactic use of epidural mepivacaine/morphine, systemic diclofenac, and metamizole reduces postoperative morphine consumption after major abdominal surgery. Anesthesiology 1996;84:1027-34.
24. Choe H, Choi Y-S, Kim Y-H, et al. Epidural morphine plus ketamine for upper abdominal surgery: improved analgesia from preincisional versus postincisional administration. Anesth Analg 1997;84:560-3.
25. Malinovsky JM, Cozian A, Lepage JY. Ketamine and midazolam neurotoxicity in the rabbit. Anesthesiology 1991;75:91-7.