Cationic proteins of neutrophil azurophilic granules: Protein-protein interaction and blockade of NADPH oxidase activation

Journal of Leukocyte Biology

Volumn 63, Issue 3, 1998, Pages 305-311

  Tal, Tal ^a   Michaela, Sharabani ^a   Irit, Aviram ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Lysozyme; Proteinase; Subcellular fractionation

Indexed keywords

BENZYLSULFONYL FLUORIDE; LYSOZYME; PHORBOL 13 ACETATE 12 MYRISTATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SERINE PROTEINASE; SERINE PROTEINASE 3; UNCLASSIFIED DRUG;

ARTICLE; CELL FRACTIONATION; CELL FREE SYSTEM; CELL GRANULE; ENZYME INHIBITION; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0031932518     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.63.3.305     Document Type: Article

References (32)

1. Badwey, J. A., Karnovsky, M. J. (1980) Active oxygen species and the functions of phagocytic leukocytes. Annu. Rev. Biochem. 49, 635-726.
2. Klebanoff, S. J. (1992) Oxygen metabolites from phagocytes. In Inflammation: Basic Principles and Clinical Correlates, 2nd ed. (J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds.) New York: Raven Press, 541-587.
3. Elsbach, P., Weiss, J. (1992) Oxygen-independent antimicrobial systems of phagocytes. In Inflammation: Basic Principles and Clinical Correlates, 2nd ed. (J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds.) New York: Raven Press, 603-636.
4. Morel, F., Doussiere, J., Vignais, P. V. (1991) The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspects. Eur. J. Biochem. 201, 523-546.
5. Segal, A. W., Abo, A. (1993) The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem. Sci. 18, 43-47.
6. Chanock, S., El Benna, J., Smith, R. M., Babior, B. M. (1994) The respiratory burst oxidase. J. Biol. Chem. 269, 24519-2452.
7. Borregaard, N. (1996) Current concepts about neutrophil granule physiology. Curr. Op. Hematol. 3, 11-18.
8. Aviram, I., Faber, A. (1990) A protein of neutrophil granules interferes with activation of NADPH oxidase in a cell-free system. Biochem. Biophys. Res. Commun. 169, 198-202.
9. Ganz, T., Selsted, M. E., Lehrer, R. I. (1990) Defensins. Eur. J. Haematol. 44, 1-8.
10. Lehrer, R. I., Barton, A., Gaher, K. A., Harwig, S. S. J., Ganz, T., Selsted, M. E. (1989) Interaction of human defensins with Escherichia coli: Mechanism of bactericidal activity. J. Clin. Invest. 84, 553-561.
11. Tal, T., Aviram, I. (1993) Defensin interferes with the activation of NADPH oxidase in a cell-free system. Biochem. Biophys. Res. Commun. 196, 636-641.
12. Klinger, E., Aviram, I. (1992) Involvement of GTP in cell-free activation of neutrophil NADPH oxidase: studies with GTP analogs. Biochem. J. 285, 635-639.
13. Philips, M. R., Abramson, S. B., Kolasinski, S. L., Haines, K. A., Weissmann, G., Rosenfeld, M. G. (1991) Low molecular weight GTP-binding proteins in human neutrophil membranes. J. Biol. Chem. 266, 1289-1298.
14. Babior, B. M., Cohen, H. J. (1981) Measurement of neutrophil function: phagocytosis, degranulation, the respiratory burst and bacterial killing. In Methods in Haematology 3, Leukocyte Function (M. J. Cline, ed.), Churchill Livingstone, New York 1-38.
15. Parkos, C. A., Cochrane, C. G., Schmitt, M., Jesaitis, A. J. (1985) Regulation of the oxidative response of human granulocytes to chemoattractants. J. Biol. Chem. 260, 6541-6547.
16. Laemmli, U. K. (1970) Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature [London] 227, 680-685.
17. Hoidal, J. R., Rao, N. V., Gray, B. (1994) Myeloblastin: leukocyte proteinase 3. Methods Enzymol. 244, 61-67.
18. Falk, R. J., Jennette, J. C. (1991) Wegener's granulomatosis, systemic vasculitis, and antineutrophil cytoplasmic autoantibodies. Annu. Rev. Med. 42, 459-469.
19. Gross W. L., Schmitt, W., Csernok, E. (1993) ANCA and associated diseases: immunodiagnostic and pathogenetic aspects. Clin. Exp. Immunol. 91, 1-12.
20. Bories, D., Raynal, M. C., Solomon, D. H., Darzynkiewicz, Z., Cayre, Y. E. (1989) Down-regulation of a serine protease, myeloblastin, causes growth arrest and differentiation of promyelocytic leukemia cells. Cell 59, 959-968.
21. Gabay, Y. E., Scott, R. W., Campanelli, D., Griffith, J., Wilde, C., Marra, M. N., Seeger, M., Nathan, C. F. (1989) Antibiotic proteins of human polymorphonuclear leukocytes. Proc. Natl. Acad. Sci. USA 86, 5610-5614.
22. Csernok, E., Ernst, M., Schmitt, W., Bainton, D. F., Gross, W. L. (1994) Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo. Clin. Exp. Immunol. 95, 244-250.
23. Halbwachs-Mecarelli, L., Bessou, G., Lesavre, P., Lopez, S., Vitko-Sarsat, V. (1995) Bimodal distribution of proteinase 3 (PR3) surface expression reflects a constitutive heterogeneity in the polymorphonuclear neutrophil pool. FEBS Lett. 374, 29-33.
24. Falk, R. J., Terrell, R. S., Charles, L. A., Jennette, J. C. (1990) Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc. Natl. Acad. Sci. USA 87, 4115-4119.
25. Bini, P., Gabay, J. E., Teitel, A., Melchior, M., Zhou, J-L., Elkon, K. B. (1992) Antineutrophil cytoplasmic autoantibodies in Wegener's granulomatosis recognize conformational epitope(s) on proteinase 3. J. Immunol. 149, 1409-1415.
26. Ludemann, J., Utecht, B., Gross, W. L. (1988) Detection and quantitation of anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis by ELISA using affinity-purified antigen. J. Immunol. Meth. 114, 167-174.
27. Dewald, B., Bretz, U., Baggiolini, M. (1983) Exocytosis induced in neutrophils by chemotactic agents and other stimuli. Agents Actions 12, 371-382.
28. Egesten, A., Breton-Gorius, J., Guichard, J., Gullberg, U., Olsson, I. (1994) The heterogeneity of azurophil granules in neutrophil promyelocytes: immunogold localization of myeloperoxidase, cathepsin G, elastase, proteinase 3, and bactericidal/permeability increasing protein. Blood 83, 2985-2994.
29. Owen, C. A., Campbell, M. A., Sannes, P. L., Boukedes, S. S., Campbell, E. J. (1995) Cell-surface-bound elastase and cathepsin G on neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteases. J. Cell Biol. 131, 775-789.
30. Avila, J. L., Convit, J. (1976) Inhibition of leukocytic lysosomal enzymes by glycosaminoglycans in vitro. Biochem. J. 160, 129-138.
31. Van Berkel, P. H. C., Geerts, M. E. J., Van Veen, H. A., Kooiman, P. M., Pieper, F. R., De Boer, H. A., Nuijens, J. H. (1995) Glycosylated and unglycosylated human lactoferrins bind iron and show identical affinities towards human lysozyme and bacterial lipopolysaccharide, but differ in their susceptibilities toward tryptic proteolysis. Biochem. J. 312, 107-114.
32. Ellison, T. T., III, Giehl, T. J. (1991) Killing of Gram-negative bacteria by lactoferrin and lysozyme. J. Clin. Invest. 88, 1080-1091.