European stroke prevention study-2 results: Serendipitous demonstration of neuroprotection induced by endogenous adenosine accumulation?

Trends in Pharmacological Sciences

Volumn 19, Issue 1, 1998, Pages 14-16

  Picano, E ^a   Abbracchio, M P ^b  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE; ANTITHROMBOCYTIC AGENT; CYCLIC AMP; CYCLIC GMP; DIPYRIDAMOLE; HYPOXANTHINE; INOSINE; PLACEBO; PROPENTOFYLLINE; SOLUFLAZINE; XANTHINE;

BLOOD BRAIN BARRIER; BRAIN PROTECTION; CLINICAL TRIAL; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; EUROPE; HUMAN; MAJOR CLINICAL STUDY; NEUROPROTECTION; PRIORITY JOURNAL; REVIEW; SECONDARY PREVENTION; STROKE; TRANSIENT ISCHEMIC ATTACK;

EID: 0031930356     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(97)01148-6     Document Type: Article

References (21)

1. Diner H. C. et al. J. Neurol. Sci. 143:1996;1-13.
2. Fitzgerald G. A. New Engl. J. Med. 316:1987;1247-1257.
3. Fredholm B. B. et al. Pharmacol. Rev. 46:1994;143-156.
4. Rudolphi K. A., Schubert P. Belardinelli L., Pelleg A. Adenosine and Adenine Nucleotides: From Molecular Biology to Integrative Physiology. 1996;391-398 Kluwer Academic Press.
5. Neary J. T., Rathbone M. P., Cattabeni F., Abbracchio M. P., Burnstock G. Trends Neurosci. 19:1996;13-18.
6. Abbracchio M. P. Drug Dev. Res. 39:1996;393-406.
7. Picano E., Michelassi C. Cardiovasc. Res. 33:1997;666-670.
8. Fischer S., Sharma H. S., Karliczek G. F., Schaper W. Mol. Brain Res. 28:1995;141-148.
9. Sollevi A. Prog. Neurobiol. 27:1986;319-349.
10. Phillis J. W., O'Regan M. H., Walter G. A. Brain Res. 481:1989;309-316.
11. Betz A. L. J. Neurochem. 44:1985;574-579.
12. Mistry G., Drummond G. I. J. Mol. Cell Cardiol. 18:1986;13-22.
13. Sage J. L., Van Uitert R. L., Duffy T. E. Stroke. 15:1984;46-50.
14. Juurlink B. H. J., Sweeney M. Neurosci. Behav. Rev. 21:1997;121-128.
15. Heistad D. D., Marcus M. L., Gourley J. K., Busija D. W. Am. J. Physiol. 239:1981;H775-H780.
16. Cornford E. M., Oldendorf W. H. Biochim. Biophys. Acta. 394:1975;211-219.
17. Colli S., Tremoli E. J. Lab. Clin. Med. 118:1991;136-145.
18. Iuliano L. et al. Free Radic. Bio. Med. 18:1995;239-247.
19. Di Perri T., Laghi Pasini F. Fisiologia e Farmacologia del Sistema Adenosinico. 1991;179-189 Edizioni Luigi Pozzi.
20. German D. C., Kredich N. M., Bjornsson T. D. Clin. Pharmacol. Ther. 45:1989;80-84.
21. Grilli M., Pizzi M., Memo M., Spano P. Science. 274:1996;1383-1385.