Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthase activity

Shock

Volumn 9, Issue 5, 1998, Pages 359-363

  Durando, Mary ^a   Fernando, Lawrence ^a   Ashton, Sarah ^a   Halushka, Perry ^a   Cook, James ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ISOENZYME; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN SYNTHASE; PTGS1 PROTEIN, HUMAN; PTGS2 PROTEIN, HUMAN; THROMBOXANE A2;

ARTICLE; BIOSYNTHESIS; CELL LINE; DRUG EFFECT; ENZYME INDUCTION; GENETIC TRANSCRIPTION; HUMAN; KINETICS; MONOCYTE; SALMONELLA ENTERITIDIS;

ARACHIDONIC ACID; CELL LINE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENZYME INDUCTION; HUMANS; ISOENZYMES; KINETICS; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MONOCYTES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; SALMONELLA ENTERITIDIS; TETRADECANOYLPHORBOL ACETATE; THROMBOXANE A2; TRANSCRIPTION, GENETIC;

EID: 0032062331     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199805000-00008     Document Type: Article

References (36)

1. Tracey KJ, Lowry SF, Cerami A: Cachetin/TNF-alpha in septic shock and septic adult respiratory distress syndrome. Am Rev Respir Dis 138:1377-1379, 1988.
2. Hack CE, De GE, Felt BR, Nuijens JH, Strack VSR, Eerenberg BA, Thijs LG, Aarden LA: Increased plasma levels of interleukin-6 in sepsis. Blood 74:1704-1710, 1989.
3. Szabó C, Thiemermann C: Invited opinion: role of nitric oxide in hemorrhagic, traumatic, and anaphylactic shock and thermal injury. Shock 2:145-155, 1994.
4. Simmons T, Halushka P, Cook J: Role of cyclo-oxygenase products in septic shock. Handbook on Mediators in Septic Shock 395-418:1993.
5. Martich GD, Boujoukos AJ, Suffredini AF: Response of man to endotoxin. Immunobiology 187:403-416, 1993.
6. Han J, Lee JD, Tobias PS, Ulevitch RJ: Endotoxin induces rapid protein tyrosine phosphorylation in 70Z/3 cells expressing CD14. J Biol Chem 268:25009-250014, 1993.
7. Sweet M, Hume D: Endotoxin signal transduction in macrophages. J Leukoc Biol 60:8-26, 1996.
8. Natarajan V, Iwamoto GK: Lipopolysaccharide-mediated signal transduction through phospholipase D activation in monocytic cell lines. Biochim Biophys Acta 1213:14-20, 1994.
9. 2 synthesis in cultured rat mesangial cells. Biochim Biophys Acta 963:429-435, 1988.
10. i2, in the promonocytic cell line U937. J Biol Chem 264:20240-20247, 1989.
11. Durando M, Makhlouf M, Simmons-Wagner R, Halushka PV, Cook JA: Endotoxin-induced desensitization of THP-1 cells is not associated with altered G protein binding or content. J Endo Res 4:97-103, 1997.
12. Geppert D, Whitehurst C, Thompson P, Beutler B: Lipopolysaccharide signals activation of tumor necrosis factor biosynthesis through the Ras/ Raf-1/MEK/MAPK pathway. Molec Med 1:93-103, 1994.
13. Geng Y, Zhang B, Lotz M: Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes. J Immunol 151:6692-6700, 1993.
14. Mukaida N, Ishikawa Y, Ikeda N, Fujioka N, Watanabe S, Kuno K, Matsushima K: Novel insight into molecular mechanism of endotoxin shock: Biochemical analysis of LPS receptor signaling in a cell-free system targeting NF-kappaB and regulation of cytokine production/action through beta2 integrin in vivo. J Leukoc Biol 59:145-151, 1996.
15. Geisel J, Cook JA, Coffee KA, Wise WC, Halushka PV: Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation. Biochim Biophys Acta 1085:15-20, 1991.
16. 2-activating peptide-induced contraction of smooth muscle is mediated by protein kinase C-MAP kinase cascade. Biochem Biophys Res Commun 217:203-210, 1995.
17. Greisman SE, Woodward WE: Mechanisms of endotoxin tolerance. III. The refractory state during continuous intravenous infusions of endotoxin. J Exp Med 121:911-933, 1965.
18. Zhang X, Morrison DC: Lipopolysaccharide-induced selective priming effects on tumor necrosis factor alpha and nitric oxide production in mouse peritoneal macrophages. J Exp Med 177:511-516, 1993.
19. Fahmi H, Chaby R: Desensitization of macrophages to endotoxin effects is not correlated with a down-regulation of lipopolysaccharide-binding sites. Cell Immunol 150:219-229, 1993.
20. Hass JG, Baeuerle PA, Riethmuller G, Ziegler HH: Molecular mechanisms in down-regulation of tumor necrosis factor expression. Proc Natl Acad Sci USA 87:9563-9567, 1990.
21. Labeta MO, Durieux JJ, Spagnoli G, Fernandez N, Wijdenes J, Herrmann R: CD14 and tolerance to lipopolysaccharide: Biochemical and functional analysis. Immuno 80:415-423, 1993.
22. Coffee KA, Halushka PV, Wise WC, Cook JA: Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance. Biochim Biophys Acta 1035:201-205, 1990.
23. Makhlouf M, Ashton SH, Hildebrandt J, Mehta N, Gettys TW, Halushka PV, Cook JA: Alterations in macrophage G proteins are associated with endotoxin tolerance. Biochim Biophys Acta 1312:163-168, 1996.
24. Rogers TS, Halushka PV, Wise WC, Cook JA: Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance. Prostaglandins 31:639-650, 1986.
25. Pueringer RJ, Hunninghake GW: Lipopolysaccharide stimulates de novo synthesis of PGHS in human alveolar macrophages. Am J Physiol 262: L78-85, 1992.
26. Funk CD, Funk LB, Kennedy ME, Pong AS, Fitzgerald GA: Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment. Federation of American Society of Experimental Biology Journal 5:2304-2312, 1991.
27. Han J, Lee JD, Tobias PS, Ulevitch RJ: Endotoxin induces rapid protein-tyrosine phosphorylation in 70Z/3 cells expressing CD14. J Biol Chem 268:25009-25014, 1993.
28. Wu KK, Hatzakis H, Lo SS, Seong DC, Sanduja SK, Tai HH: Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester. J Biol Chem 263:19043-19047, 1988.
29. Simonson MS, Wolfe JA, Konieczkowski M, Sedor JR, Dunn MJ: Regulation of prostaglandin endoperoxide synthase gene expression in cultured rat mesangial cells: Induction by serum via a protein kinase-C-dependent mechanism. Mol Endocrinol 5:441-451, 1991.
30. Laemmli UK: Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685, 1970.
31. LaRue KE., and McCall CE: A Labile transcriptional repressor modulates endotoxin tolerance. J Co-op Med 180:2269-2275, 1994.
32. Sambrook J, Fritsch, EF, Maniatis T: Molecular Cloning. A Laboratory Manual. 2nd Edition. Cold Spring Harbor Laboratory Press, pp 740-752, 1989.
33. Scherzer JA, Lin Y, McLeish KR, Klein JB: TNF translationally modulates the expression of G protein αi2 subunits in human polymorphonuclear leukocytes. J Immunol 158:913-918, 1997.
34. Geisel J, Cook JA, Ashton SH, Wise WC, Halushka PV: Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2. Am J Physiol 267:C1067-72, 1994.
35. Coffee KA, Halushka PV, Ashton SH, Tempel GE, Wise WC, Cook JA: Endotoxin tolerance is associated with altered GTP-binding protein function. J Appl Physiol 73:1008-1013, 1992.
36. Durando MM, Halushka PV, Cook JA: Diminished activation of mitogen activated protein kinase (MAPK) induced by endotoxin (LPS) desensitization in THP-1 cells. Shock 7:67, 1996.