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Volumn 66, Issue 5, 1998, Pages 2170-2179

Generation of neutralizing antipeptide antibodies to the enzymatic domain of Pseudomonas aeruginosa exotoxin A

Author keywords

[No Author keywords available]

Indexed keywords

EXOTOXIN A ANTIBODY; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEPTIDE ANTIBODY; PSEUDOMONAS EXOTOXIN; UNCLASSIFIED DRUG;

EID: 0031924786     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.5.2170-2179.1998     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 0022540281 scopus 로고
    • Structure of exotoxin A of Pseudomonas aeruginosa at 3.0 angstrom resolution
    • Allured, V. S., R. J. Collier, and D. B. McKay. 1986. Structure of exotoxin A of Pseudomonas aeruginosa at 3.0 angstrom resolution. Proc. Natl. Acad. Sci. USA 83:1320-1324.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1320-1324
    • Allured, V.S.1    Collier, R.J.2    McKay, D.B.3
  • 2
    • 0029856407 scopus 로고    scopus 로고
    • Investigation into the catalytic role for the tryptophan residues within domain III of Pseudomonas aeruginosa exotoxin A
    • Beattie, B. K., G. A. Prentice, and A. R. Merrill. 1996. Investigation into the catalytic role for the tryptophan residues within domain III of Pseudomonas aeruginosa exotoxin A. Biochemistry 35:15134-15142.
    • (1996) Biochemistry , vol.35 , pp. 15134-15142
    • Beattie, B.K.1    Prentice, G.A.2    Merrill, A.R.3
  • 3
    • 0020791999 scopus 로고
    • Analysis of 1,186 episodes of gram-negative bacteremia in non-university hospitals: The effect of antimicrobial therapy
    • Bryan, C. S., X. L. Reynolds, and E. R. Berner. 1983. Analysis of 1,186 episodes of gram-negative bacteremia in non-university hospitals: the effect of antimicrobial therapy. Rev. Infect. Dis. 5:629-638.
    • (1983) Rev. Infect. Dis. , vol.5 , pp. 629-638
    • Bryan, C.S.1    Reynolds, X.L.2    Berner, E.R.3
  • 4
    • 0023895895 scopus 로고
    • Role of domain II of Pseudomonas exotoxin in the secretion of proteins into the periplasm and medium of Escherichia coli
    • Chaudhary, V. K., Y. H. Xu, D. FitzGerald, S. Adhya, and I. Pastan. 1988. Role of domain II of Pseudomonas exotoxin in the secretion of proteins into the periplasm and medium of Escherichia coli. Proc. Natl. Acad. Sci. USA 85: 2939-2943.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 2939-2943
    • Chaudhary, V.K.1    Xu, Y.H.2    FitzGerald, D.3    Adhya, S.4    Pastan, I.5
  • 5
    • 0022602104 scopus 로고
    • Functionally distinct monoclonal antibodies reactive with enzymatically active and binding domains of Pseudomonas aeruginosa toxin A
    • Chia, J. K. S., M. Pollack, D. Avigan, and S. Steinbach. 1986. Functionally distinct monoclonal antibodies reactive with enzymatically active and binding domains of Pseudomonas aeruginosa toxin A. Infect. Immun. 52:756-762.
    • (1986) Infect. Immun. , vol.52 , pp. 756-762
    • Chia, J.K.S.1    Pollack, M.2    Avigan, D.3    Steinbach, S.4
  • 6
    • 0017754659 scopus 로고
    • Enzymatically active peptide from the adenosine diphosphate-ribosylating toxin of Pseudomonas aeruginosa
    • Chung, D. W., and R. J. Collier. 1977. Enzymatically active peptide from the adenosine diphosphate-ribosylating toxin of Pseudomonas aeruginosa. Infect. Immun. 16:832-841.
    • (1977) Infect. Immun. , vol.16 , pp. 832-841
    • Chung, D.W.1    Collier, R.J.2
  • 7
    • 0023930436 scopus 로고
    • Bacterial and host factors affecting Pseudomonas aeruginosa colonization versus bacteremia in granulocytopenic patients
    • Dick, J. D., V. Shull, J. E. Karp, and J. Valentine. 1988. Bacterial and host factors affecting Pseudomonas aeruginosa colonization versus bacteremia in granulocytopenic patients. Eur. J. Cancer Clin. Oncol. 25(Suppl. 1):S47-54.
    • (1988) Eur. J. Cancer Clin. Oncol. , vol.25 , Issue.1 SUPPL.
    • Dick, J.D.1    Shull, V.2    Karp, J.E.3    Valentine, J.4
  • 8
    • 0024499007 scopus 로고
    • The acidic triggered entry pathway of Pseudomonas exotoxin A
    • Farahbakhsh, Z. T., and B. J. Wisnieski. 1987. The acidic triggered entry pathway of Pseudomonas exotoxin A. Biochemistry 28:580-585.
    • (1987) Biochemistry , vol.28 , pp. 580-585
    • Farahbakhsh, Z.T.1    Wisnieski, B.J.2
  • 9
    • 0016725038 scopus 로고
    • Opportunistic infection in children. in the compromised host
    • Feigin, R. D., and W. T. Shearer. 1975. Opportunistic infection in children. In the compromised host. J. Pediatr. 87:677-694.
    • (1975) J. Pediatr. , vol.87 , pp. 677-694
    • Feigin, R.D.1    Shearer, W.T.2
  • 10
    • 0029837629 scopus 로고    scopus 로고
    • What is the mechanism of action of anti-tumor necrosis factor alpha antibody in rheumatoid arthritis?
    • Feldman, M. 1996. What is the mechanism of action of anti-tumor necrosis factor alpha antibody in rheumatoid arthritis? Int. Arch. Allergy Immunol. 111:362-365.
    • (1996) Int. Arch. Allergy Immunol. , vol.111 , pp. 362-365
    • Feldman, M.1
  • 11
    • 0027197807 scopus 로고
    • Comparison of mortality rates in mice with endogenous septicemia due to Pseudomonas aeruginosa isolates from different clinical sources
    • Furuya, N., Y. Hirakata, K. Tomono, T. Matsumoto, K. Takeda, M. Kaker, and K. Yamaguchi. 1993. Comparison of mortality rates in mice with endogenous septicemia due to Pseudomonas aeruginosa isolates from different clinical sources. J. Med. Microbiol. 39:141-146.
    • (1993) J. Med. Microbiol. , vol.39 , pp. 141-146
    • Furuya, N.1    Hirakata, Y.2    Tomono, K.3    Matsumoto, T.4    Takeda, K.5    Kaker, M.6    Yamaguchi, K.7
  • 13
    • 0021223821 scopus 로고
    • Cloning, nucleotide sequence and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa
    • Gray, G. L., D. H. Smith, J. S. Baldridge, R. N. Harkins, M. L. Vasil, E. Y. Chan, and H. L. Heyneker. 1984. Cloning, nucleotide sequence and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA 81:2645-2649.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 2645-2649
    • Gray, G.L.1    Smith, D.H.2    Baldridge, J.S.3    Harkins, R.N.4    Vasil, M.L.5    Chan, E.Y.6    Heyneker, H.L.7
  • 14
    • 2642679314 scopus 로고
    • Elastase activity of Pseudomonas aeruginosa isolates from hospital patients
    • Hedberg, M., J. K. Miller, and V. N. Tompkins. 1969. Elastase activity of Pseudomonas aeruginosa isolates from hospital patients. Am. J. Clin. Pathol. 52:631-633.
    • (1969) Am. J. Clin. Pathol. , vol.52 , pp. 631-633
    • Hedberg, M.1    Miller, J.K.2    Tompkins, V.N.3
  • 16
    • 0026770197 scopus 로고
    • Pseudomonas aeruginosa exotoxin A: Its role in retardation of wound healing: The 1992 Lindberg award
    • Heggers, J. P., S. Haydon, F. Ko, P. G. Hayward, S. Carp, and M. Robson. 1992. Pseudomonas aeruginosa exotoxin A: its role in retardation of wound healing: the 1992 Lindberg award. J. Wound Care Rehabil. 13:512-518.
    • (1992) J. Wound Care Rehabil. , vol.13 , pp. 512-518
    • Heggers, J.P.1    Haydon, S.2    Ko, F.3    Hayward, P.G.4    Carp, S.5    Robson, M.6
  • 17
    • 0001522617 scopus 로고    scopus 로고
    • Treatment of infections in burns
    • D. N. Herndon (ed.), W. B. Saunders Co., Ltd., London, England
    • Heggers, J. P., et al. 1996. Treatment of infections in burns, p. 98-135. In D. N. Herndon (ed.), Total burn care. W. B. Saunders Co., Ltd., London, England.
    • (1996) Total Burn Care , pp. 98-135
    • Heggers, J.P.1
  • 18
    • 0023657391 scopus 로고
    • Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli
    • Hwang, J., D. J. P. Fitzgerald, S. Adhya, and I. Pastan. 1987. Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli. Cell 48:129-136.
    • (1987) Cell , vol.48 , pp. 129-136
    • Hwang, J.1    Fitzgerald, D.J.P.2    Adhya, S.3    Pastan, I.4
  • 19
    • 0000838807 scopus 로고
    • NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin
    • Iglewski, B. H., and D. Kabat. 1975. NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin. Proc. Natl. Acad. Sci. USA 72: 2284-2288.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , pp. 2284-2288
    • Iglewski, B.H.1    Kabat, D.2
  • 20
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 226:680-685.
    • (1970) Nature , vol.226 , pp. 680-685
    • Laemmli, U.K.1
  • 21
    • 0013879137 scopus 로고
    • The role of various fractions of Pseudomonas aeruginosa in its pathogenesis. II. Effects of lecithinase and protease
    • Liu, P. V. 1966. The role of various fractions of Pseudomonas aeruginosa in its pathogenesis. II. Effects of lecithinase and protease. J. Infect. Dis. 116: 112-116.
    • (1966) J. Infect. Dis. , vol.116 , pp. 112-116
    • Liu, P.V.1
  • 22
    • 0015910040 scopus 로고
    • Exotoxins of Pseudomonas aeruginosa. I. Factors that influence the production of exotoxin A
    • Liu, P. V. 1973. Exotoxins of Pseudomonas aeruginosa. I. Factors that influence the production of exotoxin A. J. Infect. Dis. 128:506-513.
    • (1973) J. Infect. Dis. , vol.128 , pp. 506-513
    • Liu, P.V.1
  • 23
    • 0015895709 scopus 로고
    • Exotoxins of Pseudomonas aeruginosa. II. Concentration, purification, and characterization of exotoxin A
    • Liu, P. V., S. Yoshii, and H. Hsieh. 1974. Exotoxins of Pseudomonas aeruginosa. II. Concentration, purification, and characterization of exotoxin A. J. Infect. Dis. 128:514-519.
    • (1974) J. Infect. Dis. , vol.128 , pp. 514-519
    • Liu, P.V.1    Yoshii, S.2    Hsieh, H.3
  • 24
    • 0016273458 scopus 로고
    • Extracellular toxins of Pseudomonas aeruginosa
    • Liu, P. V. 1974. Extracellular toxins of Pseudomonas aeruginosa. J. Infect. Dis. 130(Suppl.):S94-99.
    • (1974) J. Infect. Dis. , vol.130 , Issue.SUPPL.
    • Liu, P.V.1
  • 25
    • 0017350046 scopus 로고
    • Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtherias: Differential cytotoxicity
    • Middlebrook, J. L., and R. B. Dorland. 1977. Response of cultured mammalian cells to the exotoxins of Pseudomonas aeruginosa and Corynebacterium diphtherias: differential cytotoxicity. Can. J. Microbiol. 23:183-189.
    • (1977) Can. J. Microbiol. , vol.23 , pp. 183-189
    • Middlebrook, J.L.1    Dorland, R.B.2
  • 26
    • 0025219117 scopus 로고
    • Induction of interleukin-1 from murine peritoneal macrophages by Pseudomonas aeruginosa exotoxin A
    • Misfeldt, M. L., P. X. Legaard, S. E. Howell, M. H. Fornella, and R. D. LeGrand. 1990, Induction of interleukin-1 from murine peritoneal macrophages by Pseudomonas aeruginosa exotoxin A. Infect. Immun. 58:978-982.
    • (1990) Infect. Immun. , vol.58 , pp. 978-982
    • Misfeldt, M.L.1    Legaard, P.X.2    Howell, S.E.3    Fornella, M.H.4    LeGrand, R.D.5
  • 27
    • 0028324229 scopus 로고
    • The effect of anti-exotoxin A on the adherence of Pseudomonas aeruginosa to hamster tracheal epithelial cells in vitro
    • Moller, P. C., M. J. Evans, R. C. Faden, L. C. Henson, B. Rogers, and J. P. Heggers. 1994. The effect of anti-exotoxin A on the adherence of Pseudomonas aeruginosa to hamster tracheal epithelial cells in vitro. Tissue Cell 26:181-188.
    • (1994) Tissue Cell , vol.26 , pp. 181-188
    • Moller, P.C.1    Evans, M.J.2    Faden, R.C.3    Henson, L.C.4    Rogers, B.5    Heggers, J.P.6
  • 28
    • 0001663398 scopus 로고
    • Production of elastase and proteinase by Pseudomonas aeruginosa
    • Morihara, K. 1964. Production of elastase and proteinase by Pseudomonas aeruginosa. J. Bacteriol. 88:745-757.
    • (1964) J. Bacteriol. , vol.88 , pp. 745-757
    • Morihara, K.1
  • 29
    • 0015640268 scopus 로고
    • Burn wounds: Microbiology, local host defenses and current therapy
    • Nathan, P., I. A. Holder, and B. G. MacMillan. 1973. Burn wounds: microbiology, local host defenses and current therapy. Crit. Rev. Clin. Lab. Sci. 4: 61-100.
    • (1973) Crit. Rev. Clin. Lab. Sci. , vol.4 , pp. 61-100
    • Nathan, P.1    Holder, I.A.2    MacMillan, B.G.3
  • 30
    • 0026099098 scopus 로고
    • Analysis of Pseudomonas exotoxin activation and conformational changes by using monoclonal antibodies as probes
    • Ogata, M., I. Pastan, and D. Fitzgerald. 1991. Analysis of Pseudomonas exotoxin activation and conformational changes by using monoclonal antibodies as probes. Infect. Immun. 59:407-414.
    • (1991) Infect. Immun. , vol.59 , pp. 407-414
    • Ogata, M.1    Pastan, I.2    Fitzgerald, D.3
  • 31
    • 0025114420 scopus 로고
    • Identification of functional epitopes of Pseudomonas aeruginosa exotoxin A using synthetic peptides and subclone products
    • Olson, J. C., A. N. Hammod, T. S. Vincent, E. H. Beachey, and B. H. Iglewsky. 1990. Identification of functional epitopes of Pseudomonas aeruginosa exotoxin A using synthetic peptides and subclone products. Mol. Immunol. 27:981-993.
    • (1990) Mol. Immunol. , vol.27 , pp. 981-993
    • Olson, J.C.1    Hammod, A.N.2    Vincent, T.S.3    Beachey, E.H.4    Iglewsky, B.H.5
  • 32
    • 0018597344 scopus 로고
    • Consensus summary on infection
    • Polk, H. C. 1979. Consensus summary on infection. J. Trauma 19:894.
    • (1979) J. Trauma , vol.19 , pp. 894
    • Polk, H.C.1
  • 33
    • 0017947049 scopus 로고
    • Toxicity of Pseudomonas aeruginosa exotoxin A for human macrophages
    • Pollack, M., and S. E. Anderson, Jr. 1978. Toxicity of Pseudomonas aeruginosa exotoxin A for human macrophages. Infect. Immun. 19:1092-1096.
    • (1978) Infect. Immun. , vol.19 , pp. 1092-1096
    • Pollack, M.1    Anderson Jr., S.E.2
  • 34
    • 0017340178 scopus 로고
    • Exotoxin production by clinical isolates of Pseudomonas aeruginosa
    • Pollack, M., N. S. Taylor, and L. T. Callahan III. 1975. Exotoxin production by clinical isolates of Pseudomonas aeruginosa. Infect. Immun. 15:776-780.
    • (1975) Infect. Immun. , vol.15 , pp. 776-780
    • Pollack, M.1    Taylor, N.S.2    Callahan III, L.T.3
  • 35
    • 0020853430 scopus 로고
    • The role of exotoxin A in disease and immunity
    • Pollack, M. 1983. The role of exotoxin A in disease and immunity. Rev. Infect. Dis. 5:s979-s984.
    • (1983) Rev. Infect. Dis. , vol.5
    • Pollack, M.1
  • 36
    • 0028149318 scopus 로고
    • Primate antibody response to immunotoxin: Scrological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin
    • Roscoe, D. M., S.-H. Jung, I. Benhar, L. Pai, B. K. Lee, and I. Pastan. 1994. Primate antibody response to immunotoxin: scrological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin. Infect. Immun. 62:5055-5065.
    • (1994) Infect. Immun. , vol.62 , pp. 5055-5065
    • Roscoe, D.M.1    Jung, S.-H.2    Benhar, I.3    Pai, L.4    Lee, B.K.5    Pastan, I.6
  • 38
    • 0026708594 scopus 로고
    • Induction of tumor necrosis factor (TNF) and interleukin-1 (IL-1) by Pseudomonas aeruginosa and exotoxin A-induced suppression of lymphoproliferation and TNF, lymphotoxin, gamma interferon, and Il-1 production in human leukocytes
    • Staugas, R. E. M., D. P. Harvey, A. Ferrante, M. Nandoskar, and A. C. Allison. 1992. Induction of tumor necrosis factor (TNF) and interleukin-1 (IL-1) by Pseudomonas aeruginosa and exotoxin A-induced suppression of lymphoproliferation and TNF, lymphotoxin, gamma interferon, and Il-1 production in human leukocytes. Infect. Immun. 60:3162-3168.
    • (1992) Infect. Immun. , vol.60 , pp. 3162-3168
    • Staugas, R.E.M.1    Harvey, D.P.2    Ferrante, A.3    Nandoskar, M.4    Allison, A.C.5
  • 39
    • 0020201574 scopus 로고
    • Pseudomonas aeruginosa exotoxin A inhibits proliferation of human bone marrow progenitor cells in vitro
    • Stuart, R. K., and M. Pollack. 1982. Pseudomonas aeruginosa exotoxin A inhibits proliferation of human bone marrow progenitor cells in vitro, Infect. Immun. 38:206-211.
    • (1982) Infect. Immun. , vol.38 , pp. 206-211
    • Stuart, R.K.1    Pollack, M.2
  • 40
    • 0013052969 scopus 로고
    • The pathology of burns and the fundamentals of burn wound sepsis
    • C. P. Artz et al. (ed.). W. B. Saunders, Philadelphia, Pa.
    • Teplitz, C. 1979. The pathology of burns and the fundamentals of burn wound sepsis, p. 45-94. In C. P. Artz et al. (ed.). Burns: a team approach. W. B. Saunders, Philadelphia, Pa.
    • (1979) Burns: A Team Approach , pp. 45-94
    • Teplitz, C.1
  • 42
    • 2642703499 scopus 로고
    • Molecular analysis of the exotoxin A gene of Pseudomonas species
    • abstr. D70, American Society for Microbiology, Washington, D.C.
    • Vasil. M. L., G. L. Gray, and C. C. Grant. 1984. Molecular analysis of the exotoxin A gene of Pseudomonas species, abstr. D70, p. 62. In Abstracts of the 84th Annual Meeting of the American Society for Microbiology 1984. American Society for Microbiology, Washington, D.C.
    • (1984) 84th Annual Meeting of the American Society for Microbiology 1984 , pp. 62
    • Vasil, M.L.1    Gray, G.L.2    Grant, C.C.3
  • 44
  • 45
    • 0025309247 scopus 로고
    • An improved conjugation method for controlled covalent coupling of synthetic peptides to proteins using glutaraldehyde in dialysis method
    • Zeggers, N., K. Gerritse, C. Deen, W. Boersma, and E. Claasen. 1990. An improved conjugation method for controlled covalent coupling of synthetic peptides to proteins using glutaraldehyde in dialysis method. J. Immunol. Methods 130:195-200.
    • (1990) J. Immunol. Methods , vol.130 , pp. 195-200
    • Zeggers, N.1    Gerritse, K.2    Deen, C.3    Boersma, W.4    Claasen, E.5


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