In vitro methionine oxidation of recombinant human leptin

Pharmaceutical Research

Volumn 15, Issue 4, 1998, Pages 632-640

  Liu, Jennifer L ^a   Lu, Kan V ^a   Eris, Tamer ^a   Katta, Viswanatham ^a   Westcott, Keith R ^a   Narhi, Linda O ^a   Lu, Hsieng S ^a  

^a AMGEN INC   (United States)

Author keywords

Leptin oxidation; Oxidation kinetics; Protein characterization; Protein structure; Recombinant human leptin

Indexed keywords

LEPTIN; METHIONINE; RECOMBINANT LEPTIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG OXIDATION; DRUG SYNTHESIS; HUMAN; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE, FUNCTION AND VARIABILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION; THERMOSTABILITY;

ADIPOSE TISSUE; DETERGENTS; ENDOPEPTIDASES; HUMANS; HYDROGEN PEROXIDE; LEPTIN; METALLOENDOPEPTIDASES; METHIONINE; OBESITY; OXIDATION-REDUCTION; PEPTIDE MAPPING; PEROXIDES; PROTEINS; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; TERT-BUTYLHYDROPEROXIDE;

EID: 0031924419     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011998331254     Document Type: Article

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